MGE detailed information
MGE type: Conjugative plasmid MGE length: 128761 bp
Accession: NZ_CP023959 Location: 1..128761 Organism: Escherichia coli strain FDAARGOS_448 Replicon: plasmid unnamed1
Accession: NZ_CP023959 Location: 1..128761 Organism: Escherichia coli strain FDAARGOS_448 Replicon: plasmid unnamed1
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| CRN68_RS00400 () | 782..1486 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| CRN68_RS00405 () | 1651..1944 | + | 294 | Protein_2 | IS30 family transposase ISAba125 | Transposase |
| CRN68_RS00410 () | 2045..2857 | + | 813 | WP_023408309.1 | Metallo-beta-lactamase type 2 | ARG |
| CRN68_RS00415 () | 2861..3226 | + | 366 | WP_004201167.1 | bleomycin binding protein Ble-MBL | - |
| CRN68_RS00420 () | 3231..3869 | + | 639 | WP_004201168.1 | phosphoribosylanthranilate isomerase | - |
| CRN68_RS00425 () | 3880..4911 | - | 1032 | WP_004201169.1 | protein-disulfide reductase DsbD N-terminal domain-containing protein | - |
| CRN68_RS00435 () | 5224..6765 | - | 1542 | WP_000050481.1 | IS91 family transposase ISVsa3 | Transposase |
| CRN68_RS00440 () | 7170..8009 | - | 840 | WP_000259031.1 | Dihydropteroate synthase | ARG |
| CRN68_RS00445 () | 8003..8350 | - | 348 | WP_000679427.1 | Multidrug transporter EmrE | ARG |
| CRN68_RS00450 () | 8514..9305 | - | 792 | WP_001206356.1 | Streptomycin 3''-adenylyltransferase | ARG |
| CRN68_RS28465 () | 9311..9601 | - | 291 | WP_001336345.1 | DUF1010 domain-containing protein | - |
| CRN68_RS00455 () | 9713..10210 | - | 498 | WP_001083725.1 | Dihydrofolate reductase | ARG |
| CRN68_RS28470 () | 10355..10654 | + | 300 | Protein_13 | class 1 integron integrase IntI1 | - |
| CRN68_RS28475 () | 10655..11008 | + | 354 | Protein_14 | chaperonin GroEL | - |
| CRN68_RS00465 () | 11235..12767 | + | 1533 | WP_001747814.1 | IS91 family transposase | - |
| CRN68_RS00475 () | 13024..13392 | + | 369 | WP_024475255.1 | mechanosensitive ion channel | - |
| CRN68_RS00480 () | 13420..14955 | - | 1536 | WP_064760451.1 | Antiseptic resistance protein | ARG |
| CRN68_RS00490 () | 15350..16030 | + | 681 | Protein_18 | IS91 family transposase ISAzo26 | Transposase |
| CRN68_RS00500 () | 16095..16799 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| CRN68_RS00505 () | 16865..17410 | + | 546 | Protein_20 | Tn3 family transposase TnpA_Tn3 | Transposase |
| CRN68_RS00510 () | 17446..17861 | - | 416 | Protein_21 | IS1 family transposase | - |
| CRN68_RS00520 () | 18110..18511 | - | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| CRN68_RS28480 () | 18444..18701 | - | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| CRN68_RS00525 () | 18794..19447 | - | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| CRN68_RS29175 () | 19545..19685 | - | 141 | WP_001333237.1 | hypothetical protein | - |
| CRN68_RS00535 () | 20386..21243 | - | 858 | WP_029702152.1 | incFII family plasmid replication initiator RepA | - |
| CRN68_RS00540 () | 21236..21310 | - | 75 | WP_001365705.1 | RepA leader peptide Tap | - |
| CRN68_RS00550 () | 21546..21803 | - | 258 | WP_000083833.1 | replication regulatory protein RepA | - |
| CRN68_RS00555 () | 22087..22293 | - | 207 | WP_032215358.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| - () | 22280..22341 | + | 62 | NuclAT_0 | - | Antitoxin Detail |
| - () | 22280..22341 | + | 62 | NuclAT_0 | - | Antitoxin Detail |
| - () | 22280..22341 | + | 62 | NuclAT_0 | - | Antitoxin Detail |
| - () | 22280..22341 | + | 62 | NuclAT_0 | - | Antitoxin Detail |
| CRN68_RS29375 () | 22480..22746 | - | 267 | WP_087757657.1 | hypothetical protein | - |
| CRN68_RS00570 () | 23121..23690 | - | 570 | WP_029702150.1 | DUF2726 domain-containing protein | - |
| CRN68_RS00575 () | 23842..24468 | - | 627 | WP_029702149.1 | hypothetical protein | - |
| CRN68_RS00580 () | 24880..25089 | - | 210 | WP_039023209.1 | hypothetical protein | - |
| CRN68_RS00585 () | 25220..25780 | - | 561 | WP_001567328.1 | fertility inhibition protein FinO | - |
| CRN68_RS00590 () | 25835..26581 | - | 747 | WP_052273601.1 | conjugal transfer pilus acetylase TraX | - |
| CRN68_RS00595 () | 26609..27355 | - | 747 | WP_001016257.1 | IS21 family transposase ISEc12 | Transposase |
| CRN68_RS00600 () | 27370..28910 | - | 1541 | Protein_37 | IS21 family transposase ISEc12 | Transposase |
| CRN68_RS00610 () | 29186..34456 | - | 5271 | WP_039052472.1 | Multifunctional conjugation protein TraI | Relaxase |
| CRN68_RS00615 () | 34538..34765 | + | 228 | WP_039023146.1 | toxin-antitoxin system antitoxin VapB | Antitoxin Detail |
| CRN68_RS00620 () | 34765..35163 | + | 399 | WP_039023147.1 | tRNA(fMet)-specific endonuclease VapC | Toxin Detail |
| CRN68_RS00625 () | 35172..37361 | - | 2190 | WP_073961454.1 | type IV conjugative transfer system coupling protein TraD | - |
| CRN68_RS00630 () | 37614..38345 | - | 732 | WP_000850422.1 | complement resistance protein TraT | - |
| CRN68_RS00635 () | 38377..38874 | - | 498 | WP_000605862.1 | entry exclusion protein | - |
| CRN68_RS00640 () | 38893..41712 | - | 2820 | WP_039023149.1 | conjugal transfer mating pair stabilization protein TraG | - |
| CRN68_RS00645 () | 41709..43082 | - | 1374 | WP_039023150.1 | conjugal transfer protein TraH | - |
| CRN68_RS00650 () | 43082..43444 | - | 363 | WP_071550055.1 | P-type conjugative transfer protein TrbJ | - |
| CRN68_RS00655 () | 43374..43919 | - | 546 | WP_039052470.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| CRN68_RS00660 () | 43906..44190 | - | 285 | WP_000624110.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| CRN68_RS00665 () | 44309..44656 | - | 348 | WP_001287894.1 | conjugal transfer protein TrbA | - |
| CRN68_RS00670 () | 44672..45415 | - | 744 | WP_001030376.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| CRN68_RS00675 () | 45408..45665 | - | 258 | WP_039023152.1 | conjugal transfer protein TrbE | - |
| CRN68_RS00680 () | 45692..47479 | - | 1788 | WP_039052473.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| CRN68_RS00685 () | 47790..48170 | - | 381 | WP_039052469.1 | hypothetical protein | - |
| CRN68_RS00690 () | 48167..48805 | - | 639 | WP_039052468.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| CRN68_RS00695 () | 48814..49806 | - | 993 | WP_000830835.1 | conjugal transfer pilus assembly protein TraU | - |
| CRN68_RS00700 () | 49803..50435 | - | 633 | WP_039052467.1 | type-F conjugative transfer system protein TraW | - |
| CRN68_RS00705 () | 50432..50818 | - | 387 | WP_000099693.1 | type-F conjugative transfer system protein TrbI | - |
| CRN68_RS00710 () | 50815..53442 | - | 2628 | WP_001064265.1 | type IV secretion system protein TraC | - |
| CRN68_RS00715 () | 53602..53823 | - | 222 | WP_001278685.1 | conjugal transfer protein TraR | - |
| CRN68_RS00720 () | 53958..54473 | - | 516 | WP_039052466.1 | type IV conjugative transfer system lipoprotein TraV | - |
| CRN68_RS00725 () | 54470..54721 | - | 252 | WP_039052465.1 | conjugal transfer protein TrbG | - |
| CRN68_RS00730 () | 54714..55082 | - | 369 | WP_071550054.1 | conjugal transfer protein TrbD | - |
| CRN68_RS00735 () | 55021..55602 | - | 582 | WP_052273600.1 | conjugal transfer protein TraP | - |
| CRN68_RS00740 () | 55571..57022 | - | 1452 | WP_039052463.1 | conjugal transfer protein TraB | - |
| CRN68_RS00745 () | 57022..57726 | - | 705 | WP_148936096.1 | type-F conjugative transfer system secretin TraK | - |
| CRN68_RS00750 () | 57737..58303 | - | 567 | WP_039052461.1 | type IV conjugative transfer system protein TraE | - |
| CRN68_RS00755 () | 58325..58636 | - | 312 | WP_000012106.1 | type IV conjugative transfer system protein TraL | - |
| CRN68_RS00760 () | 58641..59003 | - | 363 | WP_039052460.1 | type IV conjugative transfer system pilin TraA | - |
| CRN68_RS00765 () | 59036..59431 | - | 396 | WP_001309237.1 | conjugal transfer relaxosome protein TraY | - |
| CRN68_RS00770 () | 59530..60219 | - | 690 | WP_061856953.1 | conjugal transfer transcriptional regulator TraJ | - |
| CRN68_RS00775 () | 60406..60789 | - | 384 | WP_061856954.1 | relaxosome protein TraM | - |
| CRN68_RS00780 () | 61109..61711 | + | 603 | WP_077878371.1 | hypothetical protein | VF |
| CRN68_RS00785 () | 62007..62828 | - | 822 | WP_061856956.1 | DUF945 domain-containing protein | - |
| CRN68_RS00790 () | 62947..63234 | - | 288 | WP_061856957.1 | hypothetical protein | - |
| CRN68_RS29380 () | 63535..63863 | + | 329 | Protein_75 | hypothetical protein | - |
| CRN68_RS00805 () | 63854..63985 | + | 132 | Protein_76 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| CRN68_RS00810 () | 64065..64762 | - | 698 | Protein_77 | IS1 family transposase IS1G | Transposase |
| CRN68_RS00820 () | 64935..65552 | + | 618 | Protein_78 | ISL3 family transposase ISEc38 | Transposase |
| CRN68_RS00835 () | 66016..67023 | - | 1008 | WP_001232702.1 | LacI family DNA-binding transcriptional regulator | - |
| CRN68_RS00840 () | 67049..68458 | - | 1410 | WP_039052598.1 | sucrose-6-phosphate hydrolase | - |
| CRN68_RS00845 () | 68458..69828 | - | 1371 | WP_000344915.1 | sucrose-specific PTS transporter subunit IIBC | - |
| CRN68_RS00850 () | 69889..71406 | - | 1518 | WP_039052597.1 | carbohydrate porin | - |
| CRN68_RS00855 () | 71574..72494 | - | 921 | WP_039052596.1 | aminoimidazole riboside kinase | - |
| CRN68_RS29180 () | 72855..73213 | + | 359 | Protein_84 | pilus protein | - |
| CRN68_RS00870 () | 73194..73757 | - | 564 | WP_001377760.1 | class I SAM-dependent methyltransferase | - |
| CRN68_RS00875 () | 73805..75166 | - | 1362 | WP_039052595.1 | DUF3560 domain-containing protein | - |
| CRN68_RS00880 () | 75218..75447 | - | 230 | Protein_87 | hypothetical protein | - |
| CRN68_RS00900 () | 76400..76591 | - | 192 | WP_001027495.1 | hypothetical protein | - |
| CRN68_RS00905 () | 76640..76942 | - | 303 | WP_077878372.1 | antirestriction protein | - |
| CRN68_RS29385 () | 77481..77930 | - | 450 | Protein_90 | hypothetical protein | - |
| CRN68_RS00920 () | 78107..78463 | + | 357 | WP_039052614.1 | hypothetical protein | - |
| CRN68_RS00925 () | 78501..79154 | + | 654 | WP_039052615.1 | hypothetical protein | - |
| CRN68_RS00935 () | 79268..79965 | + | 698 | Protein_93 | IS1 family transposase IS1G | Transposase |
| CRN68_RS00940 () | 79986..80219 | - | 234 | Protein_94 | sodium/glutamate symporter | - |
| CRN68_RS00945 () | 80663..80983 | + | 321 | WP_000562370.1 | antibiotic biosynthesis monooxygenase | - |
| CRN68_RS00950 () | 80976..81362 | + | 387 | WP_000460651.1 | hypothetical protein | - |
| CRN68_RS00955 () | 81370..82056 | + | 687 | WP_001284954.1 | winged helix-turn-helix domain-containing protein | - |
| CRN68_RS00960 () | 82034..82657 | - | 624 | WP_000088605.1 | Tetracycline repressor protein class B from transposon Tn10 | VF |
| CRN68_RS00965 () | 82739..83944 | + | 1206 | WP_001089068.1 | Tetracycline resistance protein, class B | ARG |
| CRN68_RS00970 () | 84057..84650 | - | 594 | WP_000428546.1 | tetracyline resistance-associated transcriptional repressor TetC | - |
| CRN68_RS00975 () | 84783..85154 | + | 372 | WP_035689358.1 | Transposon Tn10 TetD protein | VF |
| CRN68_RS00980 () | 85164..86381 | - | 1218 | WP_061856962.1 | IS4 family transposase IS10R | Transposase |
| CRN68_RS00985 () | 86403..87523 | + | 1121 | WP_087758690.1 | IS3 family transposase ISSen4 | Transposase |
| CRN68_RS00995 () | 88506..89282 | + | 777 | WP_039052454.1 | hypothetical protein | - |
| CRN68_RS01000 () | 89284..91548 | + | 2265 | WP_039052447.1 | UvrD-helicase domain-containing protein | - |
| CRN68_RS01005 () | 91891..92871 | + | 981 | WP_039052448.1 | IS5 family transposase ISKpn26 | Transposase |
| CRN68_RS01015 () | 93285..94375 | + | 1091 | Protein_107 | translesion error-prone DNA polymerase V subunit UmuC | - |
| CRN68_RS01020 () | 94380..94772 | - | 393 | WP_039052449.1 | plasmid partitioning/stability family protein | - |
| CRN68_RS01025 () | 94777..95748 | - | 972 | WP_039052450.1 | plasmid segregation protein parM | - |
| CRN68_RS01030 () | 95977..96621 | + | 645 | WP_000633913.1 | AAA family ATPase | - |
| CRN68_RS01035 () | 96615..96890 | + | 276 | WP_000239529.1 | hypothetical protein | - |
| CRN68_RS01040 () | 97028..97528 | - | 501 | Protein_112 | IS91 family transposase ISAzo26 | Transposase |
| CRN68_RS01045 () | 97510..97749 | - | 240 | WP_157916581.1 | resolvase | - |
| CRN68_RS01050 () | 97856..98464 | - | 609 | WP_039052451.1 | hypothetical protein | - |
| CRN68_RS01055 () | 98534..98884 | - | 351 | WP_039052452.1 | hypothetical protein | - |
| CRN68_RS01060 () | 99562..100557 | + | 996 | WP_000246635.1 | hypothetical protein | - |
| CRN68_RS01065 () | 100561..101493 | + | 933 | WP_000991831.1 | hypothetical protein | - |
| CRN68_RS01070 () | 101786..101971 | + | 186 | WP_001586223.1 | hypothetical protein | - |
| CRN68_RS01075 () | 101972..102874 | + | 903 | WP_024187432.1 | hypothetical protein | - |
| CRN68_RS01080 () | 102876..103745 | + | 870 | WP_001586225.1 | hypothetical protein | - |
| CRN68_RS01085 () | 103802..105367 | - | 1566 | WP_001586226.1 | ATP-binding protein | - |
| CRN68_RS01090 () | 105654..106166 | + | 513 | WP_001586228.1 | hypothetical protein | - |
| CRN68_RS01095 () | 106200..107333 | - | 1134 | WP_000545985.1 | DUF3800 domain-containing protein | - |
| CRN68_RS29150 () | 107500..108272 | - | 773 | Protein_124 | hypothetical protein | - |
| CRN68_RS01110 () | 108301..108786 | - | 486 | WP_001403958.1 | hypothetical protein | - |
| CRN68_RS01115 () | 109177..111798 | + | 2622 | WP_001586230.1 | hypothetical protein | - |
| CRN68_RS01120 () | 111997..112227 | + | 231 | WP_001261274.1 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | Antitoxin Detail |
| CRN68_RS01125 () | 112316..112591 | + | 276 | WP_001403920.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| CRN68_RS28505 () | 112596..112813 | - | 218 | Protein_129 | transposase | - |
| CRN68_RS01130 () | 112814..113344 | - | 531 | WP_000348883.1 | GNAT family N-acetyltransferase | Toxin Detail |
| CRN68_RS01135 () | 113348..113617 | - | 270 | WP_001275013.1 | DUF1778 domain-containing protein | Antitoxin Detail |
| CRN68_RS01140 () | 114505..115494 | + | 990 | WP_123002471.1 | RepB family plasmid replication initiator protein | - |
| CRN68_RS01145 () | 115817..116557 | - | 741 | WP_001586233.1 | tyrosine-type recombinase/integrase | - |
| CRN68_RS01150 () | 116678..116860 | - | 183 | WP_042004909.1 | hypothetical protein | - |
| CRN68_RS01155 () | 116927..117088 | - | 162 | WP_001440647.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| CRN68_RS01160 () | 117204..117472 | - | 269 | Protein_136 | type II toxin-antitoxin system ParD family antitoxin | - |
| CRN68_RS01170 () | 117768..118508 | - | 741 | WP_029702141.1 | IS91 family transposase ISMno23 | Transposase |
| CRN68_RS01175 () | 118548..119245 | - | 698 | Protein_138 | IS1 family transposase IS1X2 | Transposase |
| CRN68_RS01185 () | 119461..119910 | - | 450 | WP_029702172.1 | hypothetical protein | - |
| CRN68_RS01190 () | 120437..120960 | + | 524 | Protein_140 | IS1 family transposase | - |
| CRN68_RS01195 () | 121052..121333 | - | 282 | Protein_141 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| CRN68_RS01205 () | 121589..122921 | - | 1333 | Protein_142 | group II intron reverse transcriptase/maturase | - |
| CRN68_RS01215 () | 123538..124398 | - | 861 | WP_000027057.1 | Beta-lactamase TEM | ARG |
| CRN68_RS01220 () | 124581..125138 | - | 558 | WP_001235713.1 | Tn3 family transposase TnpR_Tn3 | Transposase |
| CRN68_RS01230 () | 125440..126204 | + | 765 | WP_001389365.1 | IS6-like element IS6100 family transposase | - |
| CRN68_RS01240 () | 126697..127281 | - | 585 | WP_001137892.1 | TetR family transcriptional regulator | - |
| CRN68_RS01245 () | 127281..128519 | - | 1239 | WP_000004159.1 | MFS transporter | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|