MGE detailed information
MGE type: Conjugative plasmid MGE length: 147172 bp
Accession: NZ_CP021289 Location: 1..147172 Organism: Escherichia coli strain PA45B Replicon: plasmid pPA45B
Accession: NZ_CP021289 Location: 1..147172 Organism: Escherichia coli strain PA45B Replicon: plasmid pPA45B
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| PA45B_RS26285 () | 196..957 | - | 762 | WP_000020504.1 | Fe(3+) dicitrate transport ATP-binding protein FecE | VF |
| PA45B_RS26290 () | 957..1994 | - | 1038 | WP_001545318.1 | Hemin transport system permease protein HmuU | VF |
| PA45B_RS26295 () | 1994..2992 | - | 999 | WP_000756334.1 | ABC transporter substrate-binding protein | - |
| PA45B_RS27645 () | 3142..3255 | - | 114 | Protein_4 | integrase core domain-containing protein | - |
| PA45B_RS26300 () | 3248..3753 | - | 506 | Protein_5 | IS3 family transposase IS3H | Transposase |
| PA45B_RS26305 () | 4078..4869 | + | 792 | WP_000456855.1 | Virulence regulon transcriptional activator VirF | VF |
| PA45B_RS26310 () | 5074..5490 | - | 417 | WP_000466682.1 | SdiA-regulated domain-containing protein | - |
| PA45B_RS26315 () | 5702..6930 | + | 1229 | WP_106378881.1 | IS3 family transposase IS2 | Transposase |
| PA45B_RS26320 () | 7213..7698 | - | 486 | WP_001545321.1 | Dr family adhesin structural subunit | - |
| PA45B_RS26325 () | 7806..8228 | - | 423 | WP_021535642.1 | Protein AfaD | VF |
| PA45B_RS26330 () | 8244..10759 | - | 2516 | Protein_11 | F1 capsule-anchoring protein | VF |
| PA45B_RS26335 () | 10822..11574 | - | 753 | WP_000471454.1 | Chaperone protein caf1M | VF |
| PA45B_RS26345 () | 12057..12305 | + | 249 | Protein_13 | IS21 family transposase IS21 | Transposase |
| PA45B_RS26350 () | 12360..13099 | + | 740 | Protein_14 | IS3 family transposase IS629 | Transposase |
| PA45B_RS26360 () | 13772..15280 | + | 1509 | WP_001189111.1 | group II intron reverse transcriptase/maturase | - |
| PA45B_RS26365 () | 15370..15843 | + | 474 | Protein_16 | IS3 family transposase IS629 | Transposase |
| PA45B_RS26370 () | 15846..16415 | - | 570 | WP_001336919.1 | Serine protease EspC | VF |
| PA45B_RS26375 () | 16517..17496 | + | 980 | Protein_18 | IS5 family transposase ISKpn26 | Transposase |
| PA45B_RS26380 () | 17646..18278 | - | 633 | Protein_19 | histidine-type phosphatase | - |
| PA45B_RS26385 () | 18400..18885 | - | 486 | WP_000874189.1 | hypothetical protein | - |
| PA45B_RS26390 () | 18910..19395 | - | 486 | WP_001267176.1 | TlpA family protein disulfide reductase | - |
| PA45B_RS26395 () | 19382..20077 | - | 696 | WP_000117262.1 | Lipoprotein-releasing system ATP-binding protein LolD | VF |
| PA45B_RS26400 () | 20082..21212 | - | 1131 | WP_000729218.1 | ABC transporter permease | - |
| PA45B_RS26405 () | 21202..22485 | - | 1284 | WP_000964653.1 | ABC transporter permease | - |
| PA45B_RS26410 () | 22488..23867 | - | 1380 | WP_000119836.1 | DUF2318 domain-containing protein | - |
| PA45B_RS26415 () | 23971..24498 | - | 528 | WP_000178050.1 | iron transporter | - |
| PA45B_RS26420 () | 24539..26425 | - | 1887 | WP_001332815.1 | FTR1 family iron permease | - |
| PA45B_RS26430 () | 26772..27587 | - | 816 | WP_012372823.1 | Na(+)-translocating NADH-quinone reductase subunit C | - |
| PA45B_RS26435 () | 27920..28624 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| PA45B_RS27650 () | 28823..29173 | - | 351 | WP_000454193.1 | DUF3330 domain-containing protein | - |
| PA45B_RS26445 () | 29376..30389 | - | 1014 | WP_000845048.1 | IS91 family transposase ISAzo26 | Transposase |
| PA45B_RS26450 () | 30538..31329 | + | 792 | WP_001206316.1 | Streptomycin 3''-adenylyltransferase | ARG |
| PA45B_RS26455 () | 31493..31840 | + | 348 | WP_000679427.1 | Multidrug transporter EmrE | ARG |
| PA45B_RS26460 () | 31834..32673 | + | 840 | WP_000259031.1 | Dihydropteroate synthase | ARG |
| PA45B_RS26470 () | 32801..33301 | + | 501 | WP_000376623.1 | GNAT family N-acetyltransferase | - |
| PA45B_RS26475 () | 33477..34259 | - | 783 | WP_001163403.1 | IS21 family transposase IS1326 | Transposase |
| PA45B_RS26480 () | 34249..35772 | - | 1524 | WP_001324342.1 | IS21 family transposase IS1326 | Transposase |
| PA45B_RS26485 () | 35895..37439 | + | 1545 | WP_000287615.1 | IS3 family transposase IS1353 | Transposase |
| PA45B_RS26490 () | 37490..38350 | - | 861 | WP_000344784.1 | TniB family NTP-binding protein | - |
| PA45B_RS26495 () | 38353..40032 | - | 1680 | WP_021529834.1 | DDE-type integrase/transposase/recombinase | - |
| PA45B_RS26505 () | 40107..40775 | - | 669 | WP_001300294.1 | putative signaling protein | VF |
| PA45B_RS26510 () | 40811..41047 | - | 237 | WP_000993386.1 | broad-spectrum mercury transporter MerE | - |
| PA45B_RS26515 () | 41044..41406 | - | 363 | WP_001277456.1 | mercury resistance co-regulator MerD | - |
| PA45B_RS26520 () | 41424..41921 | - | 498 | Protein_44 | mercuric reductase | - |
| PA45B_RS26525 () | 42082..42942 | - | 861 | WP_000027057.1 | Beta-lactamase TEM | ARG |
| PA45B_RS26530 () | 43125..43682 | - | 558 | WP_021529835.1 | Tn3 family transposase TnpR_Tn3 | Transposase |
| PA45B_RS26535 () | 43846..46851 | + | 3006 | WP_095591311.1 | Tn3 family transposase TnpA_Tn3 | Transposase |
| PA45B_RS26540 () | 46885..46974 | - | 90 | Protein_48 | mercuric transport protein | - |
| PA45B_RS26545 () | 47046..47480 | + | 435 | WP_000429836.1 | IS607 family transposase ISChh1 | Transposase |
| PA45B_RS26550 () | 47587..48284 | - | 698 | Protein_50 | IS1 family transposase IS1R | Transposase |
| PA45B_RS26560 () | 48552..48953 | - | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| PA45B_RS27655 () | 48886..49143 | - | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| PA45B_RS26565 () | 49236..49889 | - | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| PA45B_RS27840 () | 49987..50127 | - | 141 | WP_198319705.1 | hypothetical protein | - |
| PA45B_RS26575 () | 50828..51685 | - | 858 | WP_001537577.1 | incFII family plasmid replication initiator RepA | - |
| PA45B_RS26580 () | 51678..51752 | - | 75 | WP_001365705.1 | RepA leader peptide Tap | - |
| PA45B_RS26590 () | 51986..52243 | - | 258 | WP_000084404.1 | replication regulatory protein RepA | - |
| PA45B_RS26595 () | 52528..52677 | - | 150 | WP_001336447.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| - () | 52725..52781 | + | 57 | NuclAT_1 | - | Antitoxin Detail |
| - () | 52725..52781 | + | 57 | NuclAT_1 | - | Antitoxin Detail |
| - () | 52725..52781 | + | 57 | NuclAT_1 | - | Antitoxin Detail |
| - () | 52725..52781 | + | 57 | NuclAT_1 | - | Antitoxin Detail |
| PA45B_RS26605 () | 52876..53313 | - | 438 | WP_000872609.1 | hypothetical protein | - |
| PA45B_RS26610 () | 53466..53849 | - | 384 | WP_001109264.1 | hypothetical protein | - |
| PA45B_RS26615 () | 53952..54413 | - | 462 | WP_000760080.1 | thermonuclease family protein | - |
| PA45B_RS26620 () | 55166..55369 | - | 204 | WP_001336517.1 | hypothetical protein | - |
| PA45B_RS26625 () | 55521..56078 | - | 558 | WP_000139329.1 | fertility inhibition protein FinO | - |
| PA45B_RS26630 () | 56133..56879 | - | 747 | WP_000205709.1 | conjugal transfer pilus acetylase TraX | - |
| PA45B_RS26635 () | 56899..62169 | - | 5271 | WP_001545323.1 | Multifunctional conjugation protein TraI | Relaxase |
| PA45B_RS26640 () | 62169..64430 | - | 2262 | WP_085435689.1 | type IV conjugative transfer system coupling protein TraD | - |
| PA45B_RS26645 () | 64481..65218 | - | 738 | WP_000199901.1 | hypothetical protein | - |
| PA45B_RS26650 () | 65421..66152 | - | 732 | WP_000850422.1 | complement resistance protein TraT | - |
| PA45B_RS26655 () | 66184..66681 | - | 498 | WP_000605862.1 | entry exclusion protein | - |
| PA45B_RS26660 () | 66700..69519 | - | 2820 | WP_001537571.1 | conjugal transfer mating pair stabilization protein TraG | - |
| PA45B_RS26665 () | 69516..70889 | - | 1374 | WP_000944331.1 | conjugal transfer protein TraH | - |
| PA45B_RS26670 () | 70876..71301 | - | 426 | WP_001336804.1 | F-type conjugal transfer protein TrbF | - |
| PA45B_RS26675 () | 71222..71596 | - | 375 | WP_071586940.1 | P-type conjugative transfer protein TrbJ | - |
| PA45B_RS26680 () | 71526..72071 | - | 546 | WP_000059830.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| PA45B_RS26685 () | 72058..72342 | - | 285 | WP_000624194.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| PA45B_RS26690 () | 72423..72683 | + | 261 | WP_000736412.1 | hypothetical protein | - |
| PA45B_RS26695 () | 72739..73080 | - | 342 | WP_000556795.1 | conjugal transfer protein TrbA | - |
| PA45B_RS26700 () | 73094..73837 | - | 744 | WP_001030371.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| PA45B_RS26705 () | 73830..74087 | - | 258 | WP_000864310.1 | conjugal transfer protein TrbE | - |
| PA45B_RS26710 () | 74114..75964 | - | 1851 | WP_000826177.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| PA45B_RS26715 () | 75961..76383 | - | 423 | WP_001229309.1 | HNH endonuclease | - |
| PA45B_RS26720 () | 76408..76779 | - | 372 | WP_000174465.1 | hypothetical protein | - |
| PA45B_RS26725 () | 76776..77414 | - | 639 | WP_000087539.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| PA45B_RS26730 () | 77441..77959 | - | 519 | WP_095591312.1 | hypothetical protein | - |
| PA45B_RS26735 () | 78022..78330 | - | 309 | WP_000412445.1 | hypothetical protein | - |
| PA45B_RS26740 () | 78357..79349 | - | 993 | WP_000830838.1 | conjugal transfer pilus assembly protein TraU | - |
| PA45B_RS26745 () | 79346..79978 | - | 633 | WP_001203720.1 | type-F conjugative transfer system protein TraW | - |
| PA45B_RS26750 () | 79975..80361 | - | 387 | WP_000214084.1 | type-F conjugative transfer system protein TrbI | - |
| PA45B_RS26755 () | 80358..82988 | - | 2631 | WP_000069771.1 | type IV secretion system protein TraC | - |
| PA45B_RS26770 () | 83653..84126 | - | 474 | WP_000549566.1 | hypothetical protein | - |
| PA45B_RS26775 () | 84119..84532 | - | 414 | WP_000549574.1 | hypothetical protein | - |
| PA45B_RS26780 () | 84525..84746 | - | 222 | WP_001278695.1 | conjugal transfer protein TraR | - |
| PA45B_RS26785 () | 84881..85396 | - | 516 | WP_000809872.1 | type IV conjugative transfer system lipoprotein TraV | - |
| PA45B_RS26790 () | 85396..85746 | - | 351 | WP_071586941.1 | conjugal transfer protein TrbD | - |
| PA45B_RS26795 () | 85700..86287 | - | 588 | WP_001309238.1 | conjugal transfer protein TraP | - |
| PA45B_RS26800 () | 86256..87707 | - | 1452 | WP_000146663.1 | conjugal transfer protein TraB | - |
| PA45B_RS26805 () | 87707..88435 | - | 729 | WP_001230767.1 | type-F conjugative transfer system secretin TraK | - |
| PA45B_RS26810 () | 88422..88988 | - | 567 | WP_000399780.1 | type IV conjugative transfer system protein TraE | - |
| PA45B_RS26815 () | 89010..89321 | - | 312 | WP_000012100.1 | type IV conjugative transfer system protein TraL | - |
| PA45B_RS26820 () | 89336..89695 | - | 360 | WP_001099001.1 | type IV conjugative transfer system pilin TraA | - |
| PA45B_RS26825 () | 89728..90123 | - | 396 | WP_001309237.1 | conjugal transfer relaxosome protein TraY | - |
| PA45B_RS26830 () | 90211..90900 | - | 690 | WP_000283387.1 | conjugal transfer transcriptional regulator TraJ | - |
| PA45B_RS26835 () | 91087..91470 | - | 384 | WP_001151538.1 | relaxosome protein TraM | - |
| PA45B_RS26840 () | 91791..92393 | + | 603 | Protein_104 | hypothetical protein | VF |
| PA45B_RS26845 () | 92690..93511 | - | 822 | WP_001234445.1 | DUF945 domain-containing protein | - |
| PA45B_RS26850 () | 93621..93917 | - | 297 | WP_001545326.1 | hypothetical protein | - |
| PA45B_RS27660 () | 94309..94513 | + | 205 | Protein_107 | pilus protein | - |
| PA45B_RS26865 () | 94814..94972 | - | 159 | WP_001312861.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| - () | 95016..95240 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - () | 95016..95240 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - () | 95016..95240 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - () | 95016..95240 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| PA45B_RS26870 () | 95052..95231 | + | 180 | WP_001309233.1 | hypothetical protein | - |
| PA45B_RS26875 () | 95252..95971 | - | 720 | WP_001276217.1 | plasmid SOS inhibition protein A | - |
| PA45B_RS26880 () | 95968..96402 | - | 435 | WP_021529837.1 | conjugation system SOS inhibitor PsiB | - |
| PA45B_RS26885 () | 96471..98435 | - | 1965 | WP_001537566.1 | ParB/RepB/Spo0J family partition protein | - |
| PA45B_RS26890 () | 98496..98729 | - | 234 | WP_000006003.1 | DUF905 family protein | - |
| PA45B_RS26895 () | 98787..99314 | - | 528 | WP_000290834.1 | single-stranded DNA-binding protein | - |
| PA45B_RS26915 () | 100145..100708 | - | 564 | WP_001309257.1 | class I SAM-dependent methyltransferase | - |
| PA45B_RS26920 () | 100755..102116 | - | 1362 | WP_000170705.1 | DUF3560 domain-containing protein | - |
| PA45B_RS26925 () | 102168..102398 | - | 231 | WP_001537563.1 | hypothetical protein | - |
| PA45B_RS27845 () | 103079..103387 | + | 309 | WP_050576143.1 | hypothetical protein | - |
| PA45B_RS26940 () | 103366..103557 | - | 192 | WP_001027049.1 | hypothetical protein | - |
| PA45B_RS26945 () | 103557..103976 | - | 420 | WP_000271761.1 | DUF1380 family protein | - |
| PA45B_RS26950 () | 104023..104325 | - | 303 | WP_001364029.1 | antirestriction protein | - |
| PA45B_RS27675 () | 104862..105632 | - | 771 | WP_001044390.1 | hypothetical protein | - |
| PA45B_RS26965 () | 105677..106111 | - | 435 | WP_000274451.1 | DUF1380 family protein | - |
| PA45B_RS26970 () | 106125..106346 | - | 222 | WP_001104892.1 | hypothetical protein | - |
| PA45B_RS26975 () | 106347..107030 | - | 684 | WP_000086171.1 | DNA methylase | - |
| PA45B_RS26980 () | 107106..107417 | - | 312 | WP_001309256.1 | hypothetical protein | - |
| PA45B_RS27850 () | 107481..107840 | - | 360 | WP_001336695.1 | DUF1281 domain-containing protein | - |
| PA45B_RS27855 () | 107847..107990 | - | 144 | WP_000270807.1 | DUF1281 domain-containing protein | - |
| PA45B_RS27000 () | 108157..108933 | - | 777 | Protein_129 | hypothetical protein | - |
| PA45B_RS27005 () | 109167..110129 | - | 963 | WP_000756328.1 | ParB/RepB/Spo0J family partition protein | - |
| PA45B_RS27010 () | 110126..111331 | - | 1206 | WP_000817635.1 | Plasmid partition protein A | VF |
| PA45B_RS27020 () | 112089..112340 | + | 252 | WP_001132895.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin Detail |
| PA45B_RS27025 () | 112337..112624 | + | 288 | WP_001270422.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin Detail |
| PA45B_RS27030 () | 112626..113037 | + | 412 | Protein_134 | DDE-type integrase/transposase/recombinase | - |
| PA45B_RS27040 () | 113681..114658 | + | 978 | WP_001309253.1 | RepB family plasmid replication initiator protein | - |
| PA45B_RS27045 () | 114901..115641 | - | 741 | WP_001066947.1 | IS91 family transposase ISMno23 | Transposase |
| PA45B_RS27050 () | 115762..115950 | - | 189 | WP_001332784.1 | hypothetical protein | - |
| PA45B_RS27055 () | 116317..117486 | + | 1170 | WP_001072358.1 | hypothetical protein | - |
| PA45B_RS27060 () | 117712..117887 | - | 176 | Protein_139 | IS3 family transposase | - |
| PA45B_RS27065 () | 118333..118605 | - | 273 | WP_001322642.1 | adhesin biosynthesis transcription regulatory family protein | - |
| PA45B_RS27070 () | 119130..119566 | - | 437 | Protein_141 | IS3 family transposase IS2 | Transposase |
| PA45B_RS27075 () | 119656..120135 | - | 480 | Protein_142 | IS3 family transposase IS629 | Transposase |
| PA45B_RS27080 () | 120219..121727 | - | 1509 | WP_032145081.1 | group II intron reverse transcriptase/maturase | - |
| PA45B_RS27090 () | 122400..122750 | - | 351 | Protein_144 | IS3 family transposase IS629 | Transposase |
| PA45B_RS27095 () | 122836..124335 | + | 1500 | WP_000143800.1 | IS21 family transposase ISEc10 | Transposase |
| PA45B_RS27100 () | 124332..125087 | + | 756 | WP_000065240.1 | IS21 family transposase ISEc10 | Transposase |
| PA45B_RS27105 () | 124978..125555 | - | 578 | Protein_147 | IS3 family transposase IS629 | Transposase |
| PA45B_RS27110 () | 125581..125886 | + | 306 | Protein_148 | IS91 family transposase ISSbo1 | Transposase |
| PA45B_RS27115 () | 126409..127584 | - | 1176 | WP_001020413.1 | putative protein YncE | VF |
| PA45B_RS27120 () | 127653..129914 | - | 2262 | WP_001100763.1 | TonB-dependent receptor | - |
| PA45B_RS27125 () | 130083..130859 | - | 777 | WP_000981091.1 | energy transducer TonB | - |
| PA45B_RS27130 () | 130867..131742 | - | 876 | WP_001537591.1 | ChaN family lipoprotein | - |
| PA45B_RS27135 () | 132074..132760 | - | 687 | Protein_153 | replication initiation protein | - |
| PA45B_RS27155 () | 134330..134548 | - | 219 | WP_001336934.1 | hypothetical protein | - |
| PA45B_RS27165 () | 134677..135024 | + | 348 | WP_000142452.1 | hypothetical protein | - |
| PA45B_RS27170 () | 135044..135553 | - | 510 | WP_000194542.1 | hypothetical protein | - |
| PA45B_RS27175 () | 135550..135810 | - | 261 | WP_000371883.1 | hypothetical protein | - |
| PA45B_RS27180 () | 135912..136651 | + | 740 | Protein_158 | IS3 family transposase IS629 | Transposase |
| PA45B_RS27190 () | 137324..138832 | + | 1509 | WP_032145081.1 | group II intron reverse transcriptase/maturase | - |
| PA45B_RS27195 () | 139061..140095 | - | 1035 | Protein_160 | IS3 family transposase IS3 | Transposase |
| PA45B_RS27200 () | 140211..140615 | + | 405 | WP_000839179.1 | IS66 family transposase ISEc22 | Transposase |
| PA45B_RS27205 () | 140612..140959 | + | 348 | WP_000612626.1 | IS66 family transposase ISKpn24 | Transposase |
| PA45B_RS27210 () | 141008..142546 | + | 1539 | WP_000099150.1 | IS66 family transposase ISEc22 | Transposase |
| PA45B_RS27680 () | 142585..142734 | + | 150 | Protein_164 | IS3 family transposase | - |
| PA45B_RS27220 () | 142850..143698 | + | 849 | WP_001057995.1 | 3'-5' exonuclease | - |
| PA45B_RS27225 () | 143815..144297 | + | 483 | WP_001337004.1 | hypothetical protein | - |
| PA45B_RS27230 () | 144507..144767 | + | 261 | WP_001545316.1 | hypothetical protein | - |
| PA45B_RS27235 () | 144874..145137 | + | 264 | WP_001089474.1 | hypothetical protein | - |
| PA45B_RS27240 () | 145127..145426 | + | 300 | WP_000119542.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| PA45B_RS27245 () | 145784..146059 | + | 276 | WP_000877662.1 | bacteriocin immunity protein | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|