MGE detailed information
MGE type: Conjugative plasmid MGE length: 129452 bp
Accession: NZ_CP019272 Location: 1..129452 Organism: Escherichia coli strain 13P460A Replicon: plasmid p13P460A-1
Accession: NZ_CP019272 Location: 1..129452 Organism: Escherichia coli strain 13P460A Replicon: plasmid p13P460A-1
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| BWI88_RS24435 () | 1..249 | + | 249 | WP_000083837.1 | replication regulatory protein RepA | - |
| BWI88_RS24445 () | 494..568 | + | 75 | WP_001375168.1 | RepA leader peptide Tap | - |
| BWI88_RS24450 () | 561..1418 | + | 858 | WP_032495102.1 | incFII family plasmid replication initiator RepA | - |
| BWI88_RS24460 () | 2357..3010 | + | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| BWI88_RS26655 () | 3103..3360 | + | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| BWI88_RS24465 () | 3293..3694 | + | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| BWI88_RS24480 () | 3943..4358 | + | 416 | Protein_6 | IS1 family transposase | - |
| BWI88_RS24485 () | 4394..4939 | - | 546 | Protein_7 | Tn3 family transposase TnpA_Tn3 | Transposase |
| BWI88_RS24490 () | 5005..5709 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| BWI88_RS24495 () | 5774..6454 | - | 681 | Protein_9 | IS91 family transposase ISAzo26 | Transposase |
| BWI88_RS24500 () | 6726..7430 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| BWI88_RS26660 () | 7436..7576 | + | 141 | WP_001044210.1 | hypothetical protein | - |
| BWI88_RS24510 () | 8062..8799 | + | 738 | WP_001446887.1 | Tn3 family transposase TnpR_TnEc1 | Transposase |
| BWI88_RS24515 () | 8796..9020 | + | 225 | WP_000743213.1 | hypothetical protein | - |
| BWI88_RS24520 () | 9231..10724 | + | 1494 | WP_001120888.1 | IS91 family transposase ISVsa3 | Transposase |
| BWI88_RS26825 () | 11193..11639 | + | 447 | Protein_15 | DUF3363 domain-containing protein | - |
| BWI88_RS24530 () | 11856..13070 | + | 1215 | WP_023300759.1 | Bicyclomycin resistance protein | ARG |
| BWI88_RS24535 () | 13098..13403 | + | 306 | WP_001255015.1 | HTH-type transcriptional regulator CynR | VF |
| BWI88_RS24540 () | 13515..13703 | + | 189 | Protein_18 | IS91 family transposase | - |
| BWI88_RS24545 () | 13670..14869 | - | 1200 | WP_032153701.1 | Tetracycline resistance protein, class C | ARG |
| BWI88_RS24550 () | 14975..15625 | + | 651 | WP_001493764.1 | tetracycline resistance transcriptional repressor TetR(A) | - |
| BWI88_RS24555 () | 15654..15899 | - | 246 | WP_058914914.1 | hypothetical protein | - |
| BWI88_RS24565 () | 16205..17041 | - | 837 | WP_000480968.1 | hypothetical protein | ARG |
| BWI88_RS24570 () | 17041..17844 | - | 804 | WP_001082319.1 | Aminoglycoside 3'-phosphotransferase | ARG |
| BWI88_RS24575 () | 17905..18720 | - | 816 | WP_001043260.1 | Dihydropteroate synthase | ARG |
| BWI88_RS24590 () | 19050..19226 | + | 177 | WP_000954592.1 | Arm DNA-binding domain-containing protein | - |
| BWI88_RS24595 () | 19408..20412 | - | 1005 | WP_000427619.1 | IS110 family transposase IS5075 | Transposase |
| BWI88_RS24600 () | 20491..22257 | - | 1767 | Protein_27 | Tn3 family transposase TnpA_ISPa38 | Transposase |
| BWI88_RS24610 () | 22309..23013 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| BWI88_RS24615 () | 23333..24508 | + | 1176 | WP_063865358.1 | Efflux pump periplasmic linker BepF | VF |
| BWI88_RS24620 () | 24532..27684 | + | 3153 | WP_058914901.1 | Efflux pump membrane transporter BepE | VF |
| BWI88_RS24625 () | 27754..28233 | - | 480 | WP_000888203.1 | Rrf2 family transcriptional regulator | - |
| BWI88_RS24630 () | 28322..29026 | - | 705 | WP_001067858.1 | IS6 family transposase IS15DI | Transposase |
| BWI88_RS24635 () | 29076..29312 | - | 237 | Protein_33 | hypothetical protein | - |
| BWI88_RS24640 () | 29333..30127 | - | 795 | WP_000572405.1 | Aminoglycoside 3'-phosphotransferase | ARG |
| BWI88_RS24645 () | 30156..31586 | - | 1431 | Protein_35 | IS4 family transposase IS50R | Transposase |
| BWI88_RS24650 () | 31706..31894 | + | 189 | WP_000957857.1 | hypothetical protein | - |
| BWI88_RS24655 () | 31904..33103 | + | 1200 | WP_000948429.1 | IS91 family transposase ISSbo1 | Transposase |
| BWI88_RS26665 () | 33269..33361 | + | 93 | Protein_38 | IS6 family transposase | - |
| BWI88_RS24665 () | 33600..33881 | - | 282 | WP_000220561.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin Detail |
| BWI88_RS24670 () | 33871..34122 | - | 252 | WP_000121743.1 | plasmid stabilization protein | Antitoxin Detail |
| BWI88_RS24680 () | 35357..36196 | + | 840 | WP_024129959.1 | replication initiation protein | - |
| BWI88_RS24685 () | 36217..37059 | + | 843 | WP_000435064.1 | replication initiation protein | - |
| BWI88_RS24690 () | 37063..37509 | + | 447 | WP_001074384.1 | hypothetical protein | - |
| BWI88_RS24695 () | 37577..37999 | + | 423 | WP_179292036.1 | DNA distortion polypeptide 3 | - |
| BWI88_RS24705 () | 38485..39684 | - | 1200 | WP_000948429.1 | IS91 family transposase ISSbo1 | Transposase |
| BWI88_RS24710 () | 39694..39882 | - | 189 | WP_000957857.1 | hypothetical protein | - |
| BWI88_RS26830 () | 40112..40216 | + | 105 | WP_032409716.1 | hypothetical protein | - |
| BWI88_RS24715 () | 40345..40602 | + | 258 | WP_000764642.1 | hypothetical protein | - |
| BWI88_RS24720 () | 40660..41436 | - | 777 | WP_000015958.1 | site-specific integrase | - |
| BWI88_RS24725 () | 41433..42176 | - | 744 | WP_000129823.1 | hypothetical protein | - |
| BWI88_RS24730 () | 42227..42577 | - | 351 | WP_000493378.1 | hypothetical protein | - |
| BWI88_RS24740 () | 43257..44252 | + | 996 | WP_000246635.1 | hypothetical protein | - |
| BWI88_RS24745 () | 44256..45206 | + | 951 | Protein_53 | hypothetical protein | - |
| BWI88_RS24750 () | 45482..46569 | + | 1088 | Protein_54 | transcriptional regulator | - |
| BWI88_RS24755 () | 46571..47437 | + | 867 | Protein_55 | hypothetical protein | - |
| BWI88_RS24760 () | 47494..49059 | - | 1566 | WP_000741348.1 | ATP-binding protein | - |
| BWI88_RS24770 () | 49367..49597 | + | 231 | WP_001261287.1 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | Antitoxin Detail |
| BWI88_RS24775 () | 49594..50010 | + | 417 | WP_001044768.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| BWI88_RS24780 () | 50172..52310 | - | 2139 | WP_000350635.1 | AAA family ATPase | - |
| BWI88_RS24785 () | 52664..52921 | + | 258 | WP_000343085.1 | hypothetical protein | - |
| BWI88_RS24790 () | 52921..53511 | + | 591 | WP_000194575.1 | hypothetical protein | - |
| BWI88_RS24795 () | 53774..55330 | + | 1557 | WP_024126035.1 | AAA family ATPase | - |
| BWI88_RS24800 () | 55521..56138 | + | 618 | WP_000521603.1 | hypothetical protein | - |
| BWI88_RS24805 () | 56431..57468 | - | 1038 | WP_044502555.1 | permease | - |
| BWI88_RS24810 () | 57573..57896 | + | 324 | WP_001175594.1 | helix-turn-helix domain-containing protein | - |
| BWI88_RS24815 () | 58095..58799 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| BWI88_RS24820 () | 58829..59533 | + | 705 | WP_032193599.1 | replication initiation protein | - |
| BWI88_RS24835 () | 60219..60815 | - | 597 | WP_000583524.1 | Tn3 family transposase TnpR_TnShfr1 | Transposase |
| BWI88_RS24845 () | 60872..61048 | - | 177 | Protein_69 | IS6 family transposase IS26 | Transposase |
| BWI88_RS24850 () | 61037..61840 | + | 804 | Protein_70 | Mobilization protein A | Relaxase |
| BWI88_RS24855 () | 61853..62437 | + | 585 | WP_023281055.1 | mobilization protein MobX | - |
| BWI88_RS24860 () | 62480..62932 | - | 453 | Protein_72 | restriction endonuclease | - |
| BWI88_RS24865 () | 62997..63701 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| BWI88_RS24875 () | 63711..64181 | + | 471 | WP_049824851.1 | TetR family transcriptional regulator | - |
| BWI88_RS24880 () | 64201..64989 | + | 789 | WP_014839978.1 | winged helix-turn-helix domain-containing protein | - |
| BWI88_RS24885 () | 64989..65507 | + | 519 | WP_014839979.1 | hypothetical protein | - |
| BWI88_RS24890 () | 65512..65928 | - | 417 | WP_014839980.1 | Glutathione transferase FosA | ARG |
| BWI88_RS24895 () | 66314..67018 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| BWI88_RS24900 () | 67068..67811 | + | 744 | Protein_79 | Beta-lactamase TEM | ARG |
| BWI88_RS24905 () | 68070..68546 | + | 477 | WP_013023839.1 | WbuC family cupin fold metalloprotein | - |
| BWI88_RS24910 () | 68593..69468 | - | 876 | WP_015387340.1 | Beta-lactamase CTX-M-1 | ARG |
| BWI88_RS24920 () | 69890..70594 | - | 705 | WP_001067858.1 | IS6 family transposase IS15DI | Transposase |
| BWI88_RS26835 () | 70660..70725 | + | 66 | Protein_83 | IS1 family transposase | - |
| BWI88_RS24940 () | 72174..72408 | + | 235 | Protein_84 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| BWI88_RS24945 () | 72536..72817 | + | 282 | WP_001333089.1 | hypothetical protein | - |
| BWI88_RS24950 () | 72940..73290 | - | 351 | WP_000361389.1 | plasmid partitioning/stability family protein | - |
| BWI88_RS24955 () | 73293..74255 | - | 963 | WP_000959884.1 | plasmid segregation protein ParM | - |
| BWI88_RS24960 () | 74402..74695 | + | 294 | WP_032146011.1 | hypothetical protein | - |
| BWI88_RS24970 () | 74772..75455 | + | 684 | WP_000085883.1 | DNA methylase | - |
| BWI88_RS24975 () | 75456..75677 | + | 222 | WP_001104881.1 | hypothetical protein | - |
| BWI88_RS24980 () | 75691..76125 | + | 435 | WP_000274503.1 | DUF1380 family protein | - |
| BWI88_RS26840 () | 76176..76952 | + | 777 | WP_001383963.1 | hypothetical protein | - |
| BWI88_RS24995 () | 77493..77795 | + | 303 | WP_001671341.1 | antirestriction protein | - |
| BWI88_RS25000 () | 77842..78264 | + | 423 | WP_000271762.1 | DUF1380 family protein | - |
| BWI88_RS25005 () | 78261..78452 | + | 192 | WP_001027493.1 | hypothetical protein | - |
| BWI88_RS25025 () | 79490..79720 | + | 231 | WP_000218642.1 | hypothetical protein | - |
| BWI88_RS25030 () | 79772..81133 | + | 1362 | WP_000170695.1 | DUF3560 domain-containing protein | - |
| BWI88_RS25035 () | 81180..81743 | + | 564 | WP_015059007.1 | class I SAM-dependent methyltransferase | - |
| BWI88_RS25060 () | 82580..83107 | + | 528 | WP_000290834.1 | single-stranded DNA-binding protein | - |
| BWI88_RS25065 () | 83165..83398 | + | 234 | WP_000006003.1 | DUF905 family protein | - |
| BWI88_RS25070 () | 83459..85482 | + | 2024 | Protein_101 | ParB/RepB/Spo0J family partition protein | - |
| BWI88_RS25075 () | 85551..85985 | + | 435 | WP_000845953.1 | conjugation system SOS inhibitor PsiB | - |
| BWI88_RS25080 () | 85982..86701 | + | 720 | WP_001276217.1 | plasmid SOS inhibition protein A | - |
| - () | 86713..86937 | + | 225 | NuclAT_0 | - | - |
| - () | 86713..86937 | + | 225 | NuclAT_0 | - | - |
| - () | 86713..86937 | + | 225 | NuclAT_0 | - | - |
| - () | 86713..86937 | + | 225 | NuclAT_0 | - | - |
| BWI88_RS26670 () | 86722..86901 | - | 180 | WP_001309233.1 | hypothetical protein | - |
| BWI88_RS25085 () | 86981..87139 | + | 159 | WP_001312861.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| BWI88_RS26845 () | 87377..87754 | - | 378 | Protein_106 | hypothetical protein | - |
| BWI88_RS25105 () | 88054..88350 | + | 297 | WP_001272251.1 | hypothetical protein | - |
| BWI88_RS25110 () | 88461..89282 | + | 822 | WP_001234445.1 | DUF945 domain-containing protein | - |
| BWI88_RS25115 () | 89579..90226 | - | 648 | WP_015059008.1 | hypothetical protein | VF |
| BWI88_RS25120 () | 90503..90886 | + | 384 | WP_000124981.1 | relaxosome protein TraM | - |
| BWI88_RS25125 () | 91077..91763 | + | 687 | WP_015059009.1 | PAS domain-containing protein | - |
| BWI88_RS25130 () | 91857..92084 | + | 228 | WP_001254386.1 | conjugal transfer relaxosome protein TraY | - |
| BWI88_RS25135 () | 92118..92483 | + | 366 | WP_021519752.1 | type IV conjugative transfer system pilin TraA | - |
| BWI88_RS25140 () | 92498..92809 | + | 312 | WP_000012106.1 | type IV conjugative transfer system protein TraL | - |
| BWI88_RS25145 () | 92831..93397 | + | 567 | WP_000399794.1 | type IV conjugative transfer system protein TraE | - |
| BWI88_RS25150 () | 93408..94112 | + | 705 | WP_072095570.1 | type-F conjugative transfer system secretin TraK | - |
| BWI88_RS25155 () | 94112..95539 | + | 1428 | WP_032297072.1 | conjugal transfer protein TraB | - |
| BWI88_RS25160 () | 95529..96119 | + | 591 | WP_000002778.1 | conjugal transfer protein TraP | - |
| BWI88_RS25165 () | 96073..96303 | + | 231 | WP_001352845.1 | conjugal transfer protein TrbD | - |
| BWI88_RS25170 () | 96315..96566 | + | 252 | WP_001038341.1 | conjugal transfer protein TrbG | - |
| BWI88_RS25175 () | 96563..97078 | + | 516 | WP_000809902.1 | type IV conjugative transfer system lipoprotein TraV | - |
| BWI88_RS25180 () | 97213..97434 | + | 222 | WP_001278692.1 | conjugal transfer protein TraR | - |
| BWI88_RS25185 () | 97594..100221 | + | 2628 | WP_015059012.1 | type IV secretion system protein TraC | - |
| BWI88_RS25190 () | 100218..100604 | + | 387 | WP_015059013.1 | type-F conjugative transfer system protein TrbI | - |
| BWI88_RS25195 () | 100601..101233 | + | 633 | WP_001203735.1 | type-F conjugative transfer system protein TraW | - |
| BWI88_RS25200 () | 101230..102222 | + | 993 | WP_000830838.1 | conjugal transfer pilus assembly protein TraU | - |
| BWI88_RS25205 () | 102249..102557 | + | 309 | WP_000412447.1 | hypothetical protein | - |
| BWI88_RS25210 () | 102620..103141 | + | 522 | WP_015059014.1 | hypothetical protein | - |
| BWI88_RS25215 () | 103168..103806 | + | 639 | WP_000087532.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| BWI88_RS25220 () | 103803..104174 | + | 372 | WP_000056336.1 | hypothetical protein | - |
| BWI88_RS25225 () | 104200..104622 | + | 423 | WP_001229309.1 | HNH endonuclease | - |
| BWI88_RS25230 () | 104619..106469 | + | 1851 | WP_015059015.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| BWI88_RS25235 () | 106496..106753 | + | 258 | WP_053913405.1 | conjugal transfer protein TrbE | - |
| BWI88_RS25240 () | 106746..107489 | + | 744 | WP_015059017.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| BWI88_RS25245 () | 107605..107886 | + | 282 | WP_000549793.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| BWI88_RS25250 () | 107873..108418 | + | 546 | WP_000059817.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| BWI88_RS25255 () | 108348..108722 | + | 375 | WP_071776752.1 | P-type conjugative transfer protein TrbJ | - |
| BWI88_RS25260 () | 108676..109068 | + | 393 | WP_000126338.1 | F-type conjugal transfer protein TrbF | - |
| BWI88_RS25265 () | 109055..110428 | + | 1374 | WP_000944325.1 | conjugal transfer protein TraH | - |
| BWI88_RS25270 () | 110425..113241 | + | 2817 | WP_015059018.1 | conjugal transfer mating pair stabilization protein TraG | - |
| BWI88_RS25275 () | 113274..113795 | + | 522 | WP_000632668.1 | conjugal transfer entry exclusion protein TraS | - |
| BWI88_RS25280 () | 113820..114551 | + | 732 | WP_021559024.1 | complement resistance protein TraT | - |
| BWI88_RS25285 () | 114754..115491 | + | 738 | WP_015059020.1 | hypothetical protein | - |
| BWI88_RS25290 () | 115542..117767 | + | 2226 | WP_000009363.1 | type IV conjugative transfer system coupling protein TraD | - |
| BWI88_RS25295 () | 117767..123037 | + | 5271 | WP_072648275.1 | Multifunctional conjugation protein TraI | Relaxase |
| BWI88_RS25300 () | 123057..123803 | + | 747 | WP_000205770.1 | conjugal transfer pilus acetylase TraX | - |
| BWI88_RS25305 () | 123858..124418 | + | 561 | WP_000139328.1 | fertility inhibition protein FinO | - |
| BWI88_RS25310 () | 124550..124750 | + | 201 | WP_015059022.1 | hypothetical protein | - |
| BWI88_RS25315 () | 125136..125735 | + | 600 | WP_032083981.1 | hypothetical protein | - |
| - () | 126330..126389 | - | 60 | NuclAT_1 | - | Antitoxin Detail |
| - () | 126330..126389 | - | 60 | NuclAT_1 | - | Antitoxin Detail |
| - () | 126330..126389 | - | 60 | NuclAT_1 | - | Antitoxin Detail |
| - () | 126330..126389 | - | 60 | NuclAT_1 | - | Antitoxin Detail |
| BWI88_RS25330 () | 126434..126583 | + | 150 | WP_001312851.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| BWI88_RS25335 () | 126870..127616 | - | 747 | WP_001016257.1 | IS21 family transposase ISEc12 | Transposase |
| BWI88_RS25340 () | 127631..129172 | - | 1542 | WP_001298859.1 | IS21 family transposase ISEc12 | Transposase |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|