MGE detailed information
MGE type: Conjugative plasmid MGE length: 143972 bp
Accession: NZ_CP018947 Location: 1..143972 Organism: Escherichia coli strain Ecol_224 Replicon: plasmid pEC224_1
Accession: NZ_CP018947 Location: 1..143972 Organism: Escherichia coli strain Ecol_224 Replicon: plasmid pEC224_1
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| BE957_RS01225 () | 1..219 | + | 219 | WP_000813634.1 | type II toxin-antitoxin system antitoxin CcdA | Antitoxin Detail |
| BE957_RS01230 () | 221..526 | + | 306 | WP_001159868.1 | type II toxin-antitoxin system toxin CcdB | Toxin Detail |
| BE957_RS01235 () | 527..1333 | + | 807 | WP_000016982.1 | site-specific integrase | - |
| BE957_RS01240 () | 2107..2862 | + | 756 | WP_000852146.1 | replication initiation protein RepE | - |
| BE957_RS01245 () | 3450..4616 | + | 1167 | WP_000772446.1 | Sporulation initiation inhibitor protein Soj | VF |
| BE957_RS01250 () | 4616..5587 | + | 972 | WP_000817036.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| BE957_RS01265 () | 6454..7356 | + | 903 | WP_001348615.1 | DUF1281 domain-containing protein | - |
| BE957_RS01270 () | 7360..7664 | + | 305 | Protein_7 | hypothetical protein | - |
| BE957_RS01275 () | 7741..8424 | + | 684 | WP_000086185.1 | DNA methylase | - |
| BE957_RS01280 () | 8425..8646 | + | 222 | WP_001104873.1 | hypothetical protein | - |
| BE957_RS01285 () | 8660..9094 | + | 435 | WP_000274437.1 | DUF1380 family protein | - |
| BE957_RS27790 () | 9145..9921 | + | 777 | WP_001753849.1 | hypothetical protein | - |
| BE957_RS01300 () | 10461..10763 | + | 303 | WP_001671341.1 | antirestriction protein | - |
| BE957_RS01305 () | 10810..11232 | + | 423 | WP_000271753.1 | DUF1380 family protein | - |
| BE957_RS01310 () | 11229..11420 | + | 192 | WP_001027516.1 | hypothetical protein | - |
| BE957_RS01325 () | 12455..12685 | + | 231 | WP_000218642.1 | hypothetical protein | - |
| BE957_RS01330 () | 12737..14098 | + | 1362 | WP_000170714.1 | DUF3560 domain-containing protein | - |
| BE957_RS01335 () | 14146..14709 | + | 564 | WP_001348621.1 | class I SAM-dependent methyltransferase | - |
| BE957_RS01340 () | 14735..14959 | + | 225 | WP_016238251.1 | hypothetical protein | - |
| BE957_RS01355 () | 16060..16629 | - | 570 | WP_089634947.1 | hypothetical protein | - |
| BE957_RS01370 () | 17933..18691 | + | 759 | Protein_21 | site-specific integrase | - |
| BE957_RS01375 () | 18849..19859 | + | 1011 | WP_000053332.1 | substrate-binding domain-containing protein | - |
| BE957_RS01380 () | 19955..22081 | + | 2127 | WP_000253905.1 | alpha-galactosidase | - |
| BE957_RS01385 () | 22144..23421 | + | 1278 | WP_001083369.1 | MFS transporter | - |
| BE957_RS01390 () | 23418..24851 | + | 1434 | WP_024170639.1 | glycoside hydrolase family 32 protein | - |
| BE957_RS01395 () | 25046..26440 | + | 1395 | WP_001037799.1 | carbohydrate porin | - |
| BE957_RS27800 () | 26686..26790 | - | 105 | Protein_27 | thiosulfate reductase cytochrome B subunit | - |
| BE957_RS01400 () | 26847..27540 | + | 694 | Protein_28 | IS1 family transposase IS1A | Transposase |
| BE957_RS01405 () | 27556..28179 | + | 624 | WP_000912556.1 | potassium channel family protein | - |
| BE957_RS01410 () | 28264..28515 | + | 252 | Protein_30 | iron-containing alcohol dehydrogenase | - |
| BE957_RS01415 () | 28804..29121 | - | 318 | Protein_31 | IS110 family transposase | - |
| BE957_RS01420 () | 29276..29381 | + | 106 | Protein_32 | plasmid SOS inhibition protein A | - |
| - () | 29350..29548 | + | 199 | NuclAT_0 | - | Antitoxin Detail |
| - () | 29350..29548 | + | 199 | NuclAT_0 | - | Antitoxin Detail |
| - () | 29350..29548 | + | 199 | NuclAT_0 | - | Antitoxin Detail |
| - () | 29350..29548 | + | 199 | NuclAT_0 | - | Antitoxin Detail |
| BE957_RS01425 () | 29613..29771 | + | 159 | WP_001302184.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| BE957_RS28245 () | 30439..30645 | + | 207 | WP_000275854.1 | hypothetical protein | - |
| BE957_RS01440 () | 30670..30957 | + | 288 | WP_000107242.1 | hypothetical protein | - |
| BE957_RS01445 () | 31076..31897 | + | 822 | WP_001234465.1 | DUF945 domain-containing protein | - |
| BE957_RS01450 () | 32193..32765 | - | 573 | WP_000949660.1 | hypothetical protein | VF |
| BE957_RS01455 () | 33135..33518 | + | 384 | WP_001063020.1 | relaxosome protein TraM | - |
| BE957_RS01460 () | 33709..34356 | + | 648 | WP_000332520.1 | conjugal transfer transcriptional regulator TraJ | - |
| BE957_RS01465 () | 34492..34707 | + | 216 | WP_001352842.1 | conjugal transfer relaxosome protein TraY | - |
| BE957_RS01470 () | 34750..35115 | + | 366 | WP_000340282.1 | type IV conjugative transfer system pilin TraA | - |
| BE957_RS01475 () | 35130..35441 | + | 312 | WP_000012106.1 | type IV conjugative transfer system protein TraL | - |
| BE957_RS01480 () | 35463..36029 | + | 567 | WP_000399790.1 | type IV conjugative transfer system protein TraE | - |
| BE957_RS28250 () | 36016..36201 | + | 186 | Protein_44 | traK family protein | - |
| BE957_RS01485 () | 36190..36600 | + | 411 | Protein_45 | conjugal transfer protein TraP | - |
| BE957_RS27810 () | 36587..36724 | + | 138 | WP_001553834.1 | conjugal transfer protein TrbD | - |
| BE957_RS01490 () | 36746..36907 | + | 162 | WP_000741714.1 | conjugal transfer protein TrbD | - |
| BE957_RS01495 () | 36900..37151 | + | 252 | WP_001038342.1 | conjugal transfer protein TrbG | - |
| BE957_RS01500 () | 37148..37663 | + | 516 | WP_000809832.1 | type IV conjugative transfer system lipoprotein TraV | - |
| BE957_RS01505 () | 37798..38019 | + | 222 | WP_001278692.1 | conjugal transfer protein TraR | - |
| BE957_RS01510 () | 38179..40806 | + | 2628 | WP_001064264.1 | type IV secretion system protein TraC | - |
| BE957_RS01515 () | 40803..41189 | + | 387 | WP_000099690.1 | type-F conjugative transfer system protein TrbI | - |
| BE957_RS01520 () | 41186..41818 | + | 633 | WP_001203720.1 | type-F conjugative transfer system protein TraW | - |
| BE957_RS01525 () | 41923..43113 | + | 1191 | Protein_54 | Multifunctional conjugation protein TraI | Relaxase |
| BE957_RS01530 () | 43133..43879 | + | 747 | WP_000205701.1 | conjugal transfer pilus acetylase TraX | - |
| BE957_RS01535 () | 43934..44494 | + | 561 | WP_000139363.1 | fertility inhibition protein FinO | - |
| BE957_RS01540 () | 44627..44839 | + | 213 | WP_005012601.1 | hypothetical protein | - |
| BE957_RS01550 () | 45140..45842 | - | 703 | Protein_58 | IS1 family transposase IS1S | Transposase |
| BE957_RS01560 () | 45943..46125 | + | 183 | WP_000968309.1 | hypothetical protein | - |
| - () | 46264..46325 | - | 62 | NuclAT_1 | - | - |
| - () | 46264..46325 | - | 62 | NuclAT_1 | - | - |
| - () | 46264..46325 | - | 62 | NuclAT_1 | - | - |
| - () | 46264..46325 | - | 62 | NuclAT_1 | - | - |
| BE957_RS01570 () | 46312..46518 | + | 207 | WP_015387399.1 | type I toxin-antitoxin system Hok family toxin | - |
| BE957_RS01575 () | 46802..47059 | + | 258 | WP_000083833.1 | replication regulatory protein RepA | - |
| BE957_RS01585 () | 47295..47369 | + | 75 | WP_001365705.1 | RepA leader peptide Tap | - |
| BE957_RS01590 () | 47362..47808 | + | 447 | Protein_63 | incFII family plasmid replication initiator RepA | - |
| BE957_RS01595 () | 47754..48236 | - | 483 | Protein_64 | VENN motif pre-toxin domain-containing protein | - |
| BE957_RS01600 () | 49129..50349 | + | 1221 | WP_000410951.1 | arginine deiminase | - |
| BE957_RS01605 () | 50360..51271 | + | 912 | WP_000440183.1 | carbamate kinase | - |
| BE957_RS01610 () | 51356..52360 | + | 1005 | WP_000154544.1 | Ornithine carbamoyltransferase | VF |
| BE957_RS01615 () | 52408..53811 | + | 1404 | WP_000514417.1 | YfcC family protein | - |
| BE957_RS01620 () | 53892..54371 | + | 480 | WP_001496175.1 | ArgR family transcriptional regulator | - |
| BE957_RS01625 () | 54435..54776 | - | 342 | Protein_70 | IS66 family transposase IS682 | Transposase |
| BE957_RS27815 () | 54728..54949 | - | 222 | WP_000080217.1 | hypothetical protein | - |
| BE957_RS01630 () | 54980..55330 | - | 351 | WP_000624725.1 | IS66 family insertion sequence element accessory protein TnpB | - |
| BE957_RS01635 () | 55327..55689 | - | 363 | WP_059330006.1 | IS66 family transposase ISEc23 | Transposase |
| BE957_RS01640 () | 55798..56491 | - | 694 | Protein_74 | IS1 family transposase IS1A | Transposase |
| BE957_RS01650 () | 56524..57102 | + | 579 | WP_032147503.1 | DUF2726 domain-containing protein | - |
| BE957_RS01655 () | 57515..57868 | - | 354 | WP_000005489.1 | hypothetical protein | - |
| BE957_RS01660 () | 58340..59362 | - | 1023 | WP_000156883.1 | IS110 family transposase ISSm1 | Transposase |
| BE957_RS01670 () | 59767..60024 | + | 258 | WP_000083821.1 | replication regulatory protein RepA | - |
| BE957_RS01680 () | 60260..60334 | + | 75 | WP_001365705.1 | RepA leader peptide Tap | - |
| BE957_RS01685 () | 60327..61184 | + | 858 | WP_000130948.1 | incFII family plasmid replication initiator RepA | - |
| BE957_RS01695 () | 61423..64440 | - | 3018 | WP_021740570.1 | Tn3 family transposase TnpA_IS3000 | Transposase |
| BE957_RS28255 () | 65126..65266 | + | 141 | WP_001333237.1 | hypothetical protein | - |
| BE957_RS01705 () | 65364..66017 | + | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| BE957_RS27820 () | 66110..66367 | + | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| BE957_RS01710 () | 66300..66701 | + | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| BE957_RS01715 () | 66838..69735 | - | 2898 | WP_001553819.1 | Tn3 family transposase TnpA_Tn5403 | Transposase |
| BE957_RS01720 () | 69830..70435 | + | 606 | WP_000509965.1 | Tn3 family transposase TnpR_Tn5403 | Transposase |
| BE957_RS01725 () | 70459..70971 | - | 513 | Protein_88 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| BE957_RS01735 () | 71037..71741 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| BE957_RS01740 () | 71795..72019 | + | 225 | Protein_90 | class A beta-lactamase | - |
| BE957_RS01745 () | 72180..72677 | + | 498 | Protein_91 | mercuric reductase | - |
| BE957_RS01750 () | 72695..73057 | + | 363 | WP_001277456.1 | mercury resistance co-regulator MerD | - |
| BE957_RS01755 () | 73054..73290 | + | 237 | WP_000993386.1 | broad-spectrum mercury transporter MerE | - |
| BE957_RS01760 () | 73326..73994 | + | 669 | WP_001300294.1 | putative signaling protein | VF |
| BE957_RS01770 () | 74069..75319 | + | 1251 | Protein_95 | transposase | - |
| BE957_RS01775 () | 75384..76088 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| BE957_RS01785 () | 76175..76375 | + | 201 | WP_000993264.1 | DUF3330 domain-containing protein | - |
| BE957_RS01790 () | 76501..77061 | + | 561 | WP_000147567.1 | Tn3 family transposase TnpR_TnAs3 | Transposase |
| BE957_RS01795 () | 77064..80030 | + | 2967 | WP_001138064.1 | Tn3 family transposase TnpA_TnAs3 | Transposase |
| BE957_RS01800 () | 80097..80474 | + | 378 | WP_000656305.1 | GNAT family N-acetyltransferase | - |
| BE957_RS01805 () | 80675..81334 | - | 660 | WP_000412211.1 | Chloramphenicol acetyltransferase | ARG |
| BE957_RS01820 () | 81613..82310 | + | 698 | Protein_102 | IS1 family transposase IS1R | Transposase |
| BE957_RS01825 () | 82307..82570 | + | 264 | WP_049802299.1 | antibiotic biosynthesis monooxygenase | - |
| BE957_RS01830 () | 82563..82949 | + | 387 | WP_000460651.1 | hypothetical protein | - |
| BE957_RS01835 () | 82957..83643 | + | 687 | WP_001284954.1 | winged helix-turn-helix domain-containing protein | - |
| BE957_RS01840 () | 83621..84244 | - | 624 | WP_000088605.1 | Tetracycline repressor protein class B from transposon Tn10 | VF |
| BE957_RS01845 () | 84326..85531 | + | 1206 | WP_001089068.1 | Tetracycline resistance protein, class B | ARG |
| BE957_RS01850 () | 85644..86237 | - | 594 | WP_000428546.1 | tetracyline resistance-associated transcriptional repressor TetC | - |
| BE957_RS01855 () | 86325..86726 | + | 402 | Protein_109 | Transposon Tn10 TetD protein | VF |
| BE957_RS01860 () | 86742..87439 | - | 698 | Protein_110 | IS1 family transposase IS1X2 | Transposase |
| BE957_RS28445 () | 87639..87752 | + | 114 | Protein_111 | IS6 family transposase | - |
| BE957_RS01875 () | 87902..88060 | + | 159 | WP_000449408.1 | DsbA family protein | - |
| BE957_RS01880 () | 88050..88556 | + | 507 | WP_000949452.1 | protein disulfide oxidoreductase | - |
| BE957_RS01885 () | 88739..89554 | + | 816 | WP_012372823.1 | Na(+)-translocating NADH-quinone reductase subunit C | - |
| BE957_RS01895 () | 89901..91787 | + | 1887 | WP_000118029.1 | FTR1 family iron permease | - |
| BE957_RS01900 () | 91828..92355 | + | 528 | WP_000178050.1 | iron transporter | - |
| BE957_RS01905 () | 92459..93838 | + | 1380 | WP_000119836.1 | DUF2318 domain-containing protein | - |
| BE957_RS01910 () | 93841..95124 | + | 1284 | WP_000964653.1 | ABC transporter permease | - |
| BE957_RS01915 () | 95114..96244 | + | 1131 | WP_000729220.1 | ABC transporter permease | - |
| BE957_RS01920 () | 96249..96944 | + | 696 | WP_000117262.1 | Lipoprotein-releasing system ATP-binding protein LolD | VF |
| BE957_RS01925 () | 96931..97416 | + | 486 | WP_001267177.1 | TlpA family protein disulfide reductase | - |
| BE957_RS01930 () | 97441..97926 | + | 486 | WP_000874189.1 | hypothetical protein | - |
| BE957_RS01935 () | 98048..98578 | + | 531 | Protein_123 | histidine-type phosphatase | - |
| BE957_RS01945 () | 98636..99340 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| BE957_RS01950 () | 99365..100561 | + | 1197 | Protein_125 | IS3 family transposase | - |
| BE957_RS01955 () | 100583..100816 | + | 234 | Protein_126 | Tn3 family transposase ISPsy39 | Transposase |
| BE957_RS01960 () | 100893..101201 | + | 309 | Protein_127 | IS4 family transposase ISEc13 | Transposase |
| BE957_RS01965 () | 101260..102570 | - | 1311 | WP_000476108.1 | ABC transporter substrate-binding protein | - |
| BE957_RS01970 () | 102563..103636 | - | 1074 | WP_000950177.1 | sn-glycerol-3-phosphate import ATP-binding protein UgpC | VF |
| BE957_RS01975 () | 103642..104466 | - | 825 | WP_000922702.1 | phosphodiesterase | - |
| BE957_RS01980 () | 104477..105364 | - | 888 | WP_001271561.1 | carbohydrate ABC transporter permease | - |
| BE957_RS01985 () | 105354..106232 | - | 879 | WP_000338039.1 | sugar ABC transporter permease | - |
| BE957_RS01990 () | 106363..106803 | - | 441 | Protein_133 | zinc-binding dehydrogenase | - |
| BE957_RS02000 () | 107204..108094 | + | 891 | WP_001077068.1 | dihydrodipicolinate synthase family protein | - |
| BE957_RS02005 () | 108119..108499 | + | 381 | WP_000710783.1 | Rid family detoxifying hydrolase | - |
| BE957_RS02010 () | 108532..109497 | + | 966 | WP_001022265.1 | 2-keto-3-deoxygluconate transporter | - |
| BE957_RS02015 () | 109543..110295 | - | 753 | WP_000562172.1 | IclR family transcriptional regulator | - |
| BE957_RS02020 () | 110900..111184 | + | 285 | WP_001387467.1 | ribbon-helix-helix domain-containing protein | Antitoxin Detail |
| BE957_RS02025 () | 111184..111459 | + | 276 | WP_000421272.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin Detail |
| BE957_RS02030 () | 111565..111858 | + | 294 | WP_001105060.1 | hypothetical protein | - |
| BE957_RS27825 () | 111893..112021 | - | 129 | Protein_141 | IS481 family transposase | - |
| BE957_RS02035 () | 112054..113223 | - | 1170 | WP_001072355.1 | hypothetical protein | - |
| BE957_RS02045 () | 113716..114023 | + | 308 | Protein_143 | type II toxin-antitoxin system ParD family antitoxin | - |
| BE957_RS27830 () | 114366..114548 | + | 183 | WP_042065278.1 | hypothetical protein | - |
| BE957_RS02060 () | 114669..115409 | + | 741 | WP_001066942.1 | tyrosine-type recombinase/integrase | - |
| BE957_RS02065 () | 115694..116671 | - | 978 | WP_000361612.1 | RepB family plasmid replication initiator protein | - |
| BE957_RS28260 () | 117792..118187 | + | 396 | WP_175188304.1 | hypothetical protein | - |
| BE957_RS02085 () | 118674..119371 | + | 698 | Protein_148 | IS1 family transposase IS1R | Transposase |
| BE957_RS02090 () | 119387..119716 | + | 330 | Protein_149 | TOBE domain-containing protein | - |
| BE957_RS02095 () | 119825..120757 | - | 933 | WP_000081352.1 | homocysteine S-methyltransferase | - |
| BE957_RS02100 () | 120744..122147 | - | 1404 | WP_001373486.1 | S-methylmethionine permease | - |
| BE957_RS02105 () | 122391..123371 | + | 981 | WP_000019407.1 | IS5 family transposase IS5D | Transposase |
| BE957_RS02110 () | 123599..123916 | + | 318 | WP_001513659.1 | hypothetical protein | - |
| BE957_RS02115 () | 123866..124279 | - | 414 | Protein_154 | IS3 family transposase ISLad1 | Transposase |
| BE957_RS02120 () | 124203..124562 | - | 360 | WP_001513660.1 | hypothetical protein | - |
| BE957_RS02125 () | 124590..124769 | - | 180 | WP_001513661.1 | hypothetical protein | - |
| BE957_RS02130 () | 124774..125154 | - | 381 | WP_001216034.1 | type II toxin-antitoxin system death-on-curing family toxin | Toxin Detail |
| BE957_RS02135 () | 125154..125375 | - | 222 | WP_001190712.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin Detail |
| BE957_RS02140 () | 125558..127114 | + | 1557 | WP_001553856.1 | type I restriction-modification system subunit M | - |
| BE957_RS02145 () | 127111..128394 | + | 1284 | WP_001553855.1 | restriction endonuclease subunit S | - |
| BE957_RS02150 () | 128516..131632 | + | 3117 | WP_001553854.1 | HsdR family type I site-specific deoxyribonuclease | - |
| BE957_RS02160 () | 131846..132543 | + | 698 | Protein_162 | IS1 family transposase IS1G | Transposase |
| BE957_RS02165 () | 132680..133612 | - | 933 | WP_000991832.1 | hypothetical protein | - |
| BE957_RS02170 () | 133616..134611 | - | 996 | WP_060614953.1 | hypothetical protein | - |
| BE957_RS02175 () | 135076..137214 | + | 2139 | WP_000350635.1 | AAA family ATPase | - |
| BE957_RS02180 () | 137376..137792 | - | 417 | WP_001044768.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| BE957_RS02185 () | 137789..138019 | - | 231 | WP_001261287.1 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | Antitoxin Detail |
| BE957_RS02195 () | 138326..141445 | + | 3120 | WP_001553851.1 | hypothetical protein | - |
| BE957_RS02200 () | 141708..142841 | + | 1134 | WP_000545983.1 | DUF3800 domain-containing protein | - |
| BE957_RS02205 () | 142861..143145 | + | 285 | WP_000642771.1 | hypothetical protein | - |
| BE957_RS02210 () | 143142..143339 | - | 198 | WP_000215657.1 | hypothetical protein | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|