MGE detailed information
MGE type: Conjugative plasmid MGE length: 147225 bp
Accession: NZ_CP017221 Location: 1..147225 Organism: Escherichia coli strain FAM21845 Replicon: plasmid pFAM21845_1
Accession: NZ_CP017221 Location: 1..147225 Organism: Escherichia coli strain FAM21845 Replicon: plasmid pFAM21845_1
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| BHT24_RS25825 () | 1..978 | + | 978 | WP_000361612.1 | RepB family plasmid replication initiator protein | - |
| BHT24_RS25830 () | 1257..1997 | - | 741 | WP_001066941.1 | tyrosine-type recombinase/integrase | - |
| BHT24_RS25835 () | 2118..2306 | - | 189 | WP_032141192.1 | hypothetical protein | - |
| BHT24_RS25840 () | 2673..3842 | + | 1170 | WP_001072359.1 | hypothetical protein | - |
| BHT24_RS27725 () | 4068..4243 | - | 176 | Protein_4 | IS3 family transposase | - |
| BHT24_RS25845 () | 4689..4961 | - | 273 | WP_071526560.1 | Major pilu subunit operon regulatory protein PapB | VF |
| BHT24_RS25850 () | 5091..6703 | - | 1613 | Protein_6 | IS66 family transposase ISEc43 | Transposase |
| BHT24_RS25855 () | 6734..7084 | - | 351 | WP_000624688.1 | IS66 family transposase ISEc47 | Transposase |
| BHT24_RS25860 () | 7081..7515 | - | 435 | WP_001309734.1 | IS66 family transposase ISEc43 | Transposase |
| BHT24_RS25870 () | 7846..9816 | + | 1971 | WP_001298664.1 | Hemin receptor | VF |
| BHT24_RS25875 () | 9823..10614 | + | 792 | WP_000977395.1 | DUF4198 domain-containing protein | - |
| BHT24_RS25880 () | 10673..11428 | - | 756 | Protein_11 | IS66 family transposase ISEc23 | Transposase |
| BHT24_RS25890 () | 11491..12195 | + | 705 | WP_001067858.1 | IS6 family transposase IS15DI | Transposase |
| BHT24_RS25900 () | 12477..13691 | + | 1215 | WP_001532073.1 | type II site-specific deoxyribonuclease | - |
| BHT24_RS25905 () | 13725..15128 | - | 1404 | WP_072135327.1 | DNA cytosine methyltransferase | - |
| BHT24_RS25910 () | 15252..15524 | + | 273 | Protein_15 | IS1 family transposase IS1X2 | Transposase |
| BHT24_RS25915 () | 15518..15880 | - | 363 | WP_000275181.1 | Transposon Tn10 TetD protein | VF |
| BHT24_RS25920 () | 15968..16561 | + | 594 | WP_000428546.1 | tetracyline resistance-associated transcriptional repressor TetC | - |
| BHT24_RS25925 () | 16674..17879 | - | 1206 | WP_001089064.1 | Tetracycline resistance protein, class B | ARG |
| BHT24_RS25930 () | 17961..18584 | + | 624 | WP_000088605.1 | Tetracycline repressor protein class B from transposon Tn10 | VF |
| BHT24_RS25935 () | 18562..19248 | - | 687 | WP_001284954.1 | winged helix-turn-helix domain-containing protein | - |
| BHT24_RS25940 () | 19256..19642 | - | 387 | WP_000460651.1 | hypothetical protein | - |
| BHT24_RS25945 () | 19635..19955 | - | 321 | WP_000562370.1 | antibiotic biosynthesis monooxygenase | - |
| BHT24_RS25950 () | 20399..21604 | + | 1206 | WP_000599533.1 | sodium/glutamate symporter | - |
| BHT24_RS25955 () | 21835..21954 | + | 120 | Protein_24 | LysR family transcriptional regulator | - |
| BHT24_RS25960 () | 21970..23178 | - | 1209 | WP_001352368.1 | IS4 family transposase IS10R | Transposase |
| BHT24_RS25965 () | 23464..24267 | + | 804 | WP_001082319.1 | Aminoglycoside 3'-phosphotransferase | ARG |
| BHT24_RS25970 () | 24267..25103 | + | 837 | WP_000480968.1 | hypothetical protein | ARG |
| BHT24_RS25980 () | 25439..26254 | + | 816 | WP_000018321.1 | Aminoglycoside 3'-phosphotransferase | ARG |
| BHT24_RS25985 () | 26408..27283 | - | 876 | WP_001201005.1 | acyl-CoA--6-aminopenicillanic acid acyl-transferase | - |
| BHT24_RS25990 () | 27353..28852 | - | 1500 | Protein_30 | Tn3 family transposase TnpA_ISRsp12 | Transposase |
| BHT24_RS25995 () | 28938..29690 | + | 753 | WP_000602738.1 | IS6 family transposase ISRle7 | Transposase |
| BHT24_RS26000 () | 29741..30106 | - | 366 | Protein_32 | AAC(3) family N-acetyltransferase | - |
| BHT24_RS26005 () | 30112..31137 | - | 1026 | WP_000742814.1 | Hygromycin-B 4-O-kinase | ARG |
| BHT24_RS26015 () | 31366..32142 | - | 777 | WP_001199192.1 | SPBc2 prophage-derived aminoglycoside N(3')-acetyltransferase-like protein YokD | ARG |
| BHT24_RS26020 () | 32256..32960 | + | 705 | WP_001067856.1 | IS6 family transposase IS15DII | Transposase |
| BHT24_RS26025 () | 33015..34070 | - | 1056 | Protein_36 | Tn3 family transposase TnpA_ISRsp12 | Transposase |
| BHT24_RS26030 () | 34196..34810 | + | 615 | WP_000904906.1 | Tn3 family transposase TnpR_ISMex22 | Transposase |
| BHT24_RS26035 () | 34929..36061 | + | 1133 | Protein_38 | IS3 family transposase ISAba14 | Transposase |
| BHT24_RS26040 () | 36161..36964 | + | 804 | WP_001082319.1 | Aminoglycoside 3'-phosphotransferase | ARG |
| BHT24_RS26045 () | 36964..37800 | + | 837 | WP_000480968.1 | hypothetical protein | ARG |
| BHT24_RS26050 () | 37772..38890 | - | 1119 | WP_000845049.1 | IS91 family transposase ISAzo26 | Transposase |
| BHT24_RS26055 () | 39047..39520 | + | 474 | WP_000777555.1 | Dihydrofolate reductase type 1 | ARG |
| BHT24_RS26060 () | 39613..40404 | + | 792 | WP_001206317.1 | Streptomycin 3''-adenylyltransferase | ARG |
| BHT24_RS26065 () | 40568..40915 | + | 348 | WP_000679427.1 | Multidrug transporter EmrE | ARG |
| BHT24_RS26070 () | 40909..41748 | + | 840 | WP_000259031.1 | Dihydropteroate synthase | ARG |
| BHT24_RS26080 () | 41876..42376 | + | 501 | WP_000376623.1 | GNAT family N-acetyltransferase | - |
| BHT24_RS26085 () | 42552..43334 | - | 783 | WP_001163403.1 | IS21 family transposase IS1326 | Transposase |
| BHT24_RS26090 () | 43324..44847 | - | 1524 | WP_001324342.1 | IS21 family transposase IS1326 | Transposase |
| BHT24_RS26095 () | 44949..45137 | - | 189 | WP_033559670.1 | hypothetical protein | - |
| BHT24_RS26100 () | 45139..48144 | - | 3006 | WP_001143775.1 | Tn3 family transposase TnpA_Tn3 | Transposase |
| BHT24_RS26105 () | 48306..48863 | + | 558 | WP_001217881.1 | Tn3 family transposase TnpR_Tn3 | Transposase |
| BHT24_RS26110 () | 49046..49906 | + | 861 | WP_000027057.1 | Beta-lactamase TEM | ARG |
| BHT24_RS26115 () | 50055..50762 | - | 708 | Protein_53 | TniB family NTP-binding protein | - |
| BHT24_RS26120 () | 50765..52444 | - | 1680 | WP_000179844.1 | DDE-type integrase/transposase/recombinase | - |
| BHT24_RS26130 () | 52519..53187 | - | 669 | WP_001300294.1 | putative signaling protein | VF |
| BHT24_RS26135 () | 53223..53459 | - | 237 | WP_000993386.1 | broad-spectrum mercury transporter MerE | - |
| BHT24_RS26140 () | 53456..53818 | - | 363 | WP_001277456.1 | mercury resistance co-regulator MerD | - |
| BHT24_RS26145 () | 53836..55530 | - | 1695 | WP_000105636.1 | mercury(II) reductase | - |
| BHT24_RS26150 () | 55582..56004 | - | 423 | WP_001340589.1 | organomercurial transporter MerC | - |
| BHT24_RS26155 () | 56040..56315 | - | 276 | WP_000732292.1 | mercury resistance system periplasmic binding protein MerP | - |
| BHT24_RS26160 () | 56329..56679 | - | 351 | WP_001294663.1 | mercuric transport protein MerT | - |
| BHT24_RS26165 () | 56751..57185 | + | 435 | WP_000429836.1 | IS607 family transposase ISChh1 | Transposase |
| BHT24_RS26170 () | 57292..57989 | - | 698 | Protein_63 | IS1 family transposase IS1R | Transposase |
| BHT24_RS26180 () | 58152..58553 | - | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| BHT24_RS27735 () | 58486..58743 | - | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| BHT24_RS26185 () | 58836..59489 | - | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| BHT24_RS28085 () | 59587..59727 | - | 141 | WP_001333237.1 | hypothetical protein | - |
| BHT24_RS26195 () | 60427..61284 | - | 858 | WP_000131010.1 | incFII family plasmid replication initiator RepA | - |
| BHT24_RS26200 () | 61277..61351 | - | 75 | WP_001365705.1 | RepA leader peptide Tap | - |
| BHT24_RS26210 () | 61598..61846 | - | 249 | WP_000083835.1 | replication regulatory protein RepA | - |
| BHT24_RS26215 () | 62130..62336 | - | 207 | WP_001553767.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| - () | 62323..62384 | + | 62 | NuclAT_2 | - | Antitoxin Detail |
| - () | 62323..62384 | + | 62 | NuclAT_2 | - | Antitoxin Detail |
| - () | 62323..62384 | + | 62 | NuclAT_2 | - | Antitoxin Detail |
| - () | 62323..62384 | + | 62 | NuclAT_2 | - | Antitoxin Detail |
| BHT24_RS26225 () | 62559..62941 | - | 383 | Protein_72 | hypothetical protein | - |
| BHT24_RS26230 () | 63044..63505 | - | 462 | WP_000760078.1 | thermonuclease family protein | - |
| BHT24_RS26235 () | 64248..64451 | - | 204 | WP_001327131.1 | hypothetical protein | - |
| BHT24_RS26240 () | 64606..65163 | - | 558 | WP_000139312.1 | fertility inhibition protein FinO | - |
| BHT24_RS26245 () | 65266..66126 | - | 861 | WP_000704512.1 | putative protein YcjY | VF |
| BHT24_RS26250 () | 66185..66931 | - | 747 | WP_000205745.1 | conjugal transfer pilus acetylase TraX | - |
| BHT24_RS26255 () | 66951..72221 | - | 5271 | WP_000986969.1 | Multifunctional conjugation protein TraI | Relaxase |
| BHT24_RS26260 () | 72303..72530 | + | 228 | WP_000450520.1 | toxin-antitoxin system antitoxin VapB | - |
| BHT24_RS26265 () | 72530..72928 | + | 399 | WP_000911313.1 | tRNA(fMet)-specific endonuclease VapC | Toxin Detail |
| BHT24_RS26270 () | 72937..75090 | - | 2154 | WP_000009324.1 | type IV conjugative transfer system coupling protein TraD | - |
| BHT24_RS26275 () | 75343..76074 | - | 732 | WP_023565183.1 | complement resistance protein TraT | - |
| BHT24_RS26280 () | 76106..76603 | - | 498 | WP_000605859.1 | entry exclusion protein | - |
| BHT24_RS26285 () | 76619..79441 | - | 2823 | WP_001007016.1 | conjugal transfer mating pair stabilization protein TraG | - |
| BHT24_RS26290 () | 79438..80811 | - | 1374 | WP_001517790.1 | conjugal transfer protein TraH | - |
| BHT24_RS26295 () | 80811..81224 | - | 414 | WP_001331260.1 | F-type conjugal transfer protein TrbF | - |
| BHT24_RS26300 () | 81178..81519 | - | 342 | WP_001443031.1 | P-type conjugative transfer protein TrbJ | - |
| BHT24_RS26305 () | 81449..81994 | - | 546 | WP_000059851.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| BHT24_RS26310 () | 81981..82265 | - | 285 | WP_000624109.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| BHT24_RS26315 () | 82346..82660 | + | 315 | WP_000415566.1 | protein ArtA | - |
| BHT24_RS26320 () | 82662..83009 | - | 348 | WP_001287910.1 | conjugal transfer protein TrbA | - |
| BHT24_RS26325 () | 83025..83768 | - | 744 | WP_001030378.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| BHT24_RS26330 () | 83761..84018 | - | 258 | WP_000864318.1 | conjugal transfer protein TrbE | - |
| BHT24_RS26335 () | 84045..85853 | - | 1809 | WP_000821840.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| BHT24_RS26340 () | 85850..86488 | - | 639 | WP_000777690.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| BHT24_RS26345 () | 86497..87489 | - | 993 | WP_000830835.1 | conjugal transfer pilus assembly protein TraU | - |
| BHT24_RS26350 () | 87486..88118 | - | 633 | WP_001203750.1 | type-F conjugative transfer system protein TraW | - |
| BHT24_RS26355 () | 88115..88501 | - | 387 | WP_000099693.1 | type-F conjugative transfer system protein TrbI | - |
| BHT24_RS26360 () | 88498..91125 | - | 2628 | WP_001064265.1 | type IV secretion system protein TraC | - |
| BHT24_RS26365 () | 91285..91506 | - | 222 | WP_001278686.1 | conjugal transfer protein TraR | - |
| BHT24_RS26370 () | 91641..92156 | - | 516 | WP_000809885.1 | type IV conjugative transfer system lipoprotein TraV | - |
| BHT24_RS26375 () | 92153..92404 | - | 252 | WP_001038331.1 | conjugal transfer protein TrbG | - |
| BHT24_RS26380 () | 92397..92765 | - | 369 | WP_071526483.1 | DUF2689 domain-containing protein | - |
| BHT24_RS26385 () | 92704..93285 | - | 582 | WP_023565182.1 | conjugal transfer protein TraP | - |
| BHT24_RS26390 () | 93254..94705 | - | 1452 | WP_000146659.1 | conjugal transfer protein TraB | - |
| BHT24_RS26395 () | 94705..95409 | - | 705 | WP_148935590.1 | type-F conjugative transfer system secretin TraK | - |
| BHT24_RS26400 () | 95420..95986 | - | 567 | WP_000399792.1 | type IV conjugative transfer system protein TraE | - |
| BHT24_RS26405 () | 96008..96319 | - | 312 | WP_000012106.1 | type IV conjugative transfer system protein TraL | - |
| BHT24_RS26410 () | 96324..96686 | - | 363 | WP_000994784.1 | type IV conjugative transfer system pilin TraA | - |
| BHT24_RS26415 () | 96719..97114 | - | 396 | WP_001366159.1 | conjugal transfer relaxosome protein TraY | - |
| BHT24_RS26420 () | 97213..97902 | - | 690 | WP_000283383.1 | conjugal transfer transcriptional regulator TraJ | - |
| BHT24_RS26425 () | 98089..98472 | - | 384 | WP_001151528.1 | relaxosome protein TraM | - |
| BHT24_RS26430 () | 98793..99395 | + | 603 | WP_000243710.1 | hypothetical protein | VF |
| BHT24_RS26435 () | 99692..100513 | - | 822 | WP_001234423.1 | DUF945 domain-containing protein | - |
| BHT24_RS26440 () | 100633..100830 | - | 198 | WP_052318758.1 | hypothetical protein | - |
| BHT24_RS26450 () | 101186..101398 | - | 213 | WP_001208963.1 | hypothetical protein | - |
| BHT24_RS26465 () | 101840..101998 | - | 159 | WP_001312861.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| - () | 102042..102073 | - | 32 | NuclAT_1 | - | Antitoxin Detail |
| - () | 102042..102073 | - | 32 | NuclAT_1 | - | Antitoxin Detail |
| - () | 102042..102073 | - | 32 | NuclAT_1 | - | Antitoxin Detail |
| - () | 102042..102073 | - | 32 | NuclAT_1 | - | Antitoxin Detail |
| - () | 103515..103712 | - | 198 | NuclAT_0 | - | - |
| - () | 103515..103712 | - | 198 | NuclAT_0 | - | - |
| - () | 103515..103712 | - | 198 | NuclAT_0 | - | - |
| - () | 103515..103712 | - | 198 | NuclAT_0 | - | - |
| BHT24_RS27940 () | 103524..103712 | + | 189 | WP_001299721.1 | hypothetical protein | - |
| BHT24_RS26475 () | 103724..104443 | - | 720 | WP_081178411.1 | plasmid SOS inhibition protein A | - |
| BHT24_RS26480 () | 104440..104874 | - | 435 | WP_000845932.1 | conjugation system SOS inhibitor PsiB | - |
| BHT24_RS26490 () | 104929..106887 | - | 1959 | Protein_122 | ParB/RepB/Spo0J family partition protein | - |
| BHT24_RS26495 () | 106953..107186 | - | 234 | WP_000005990.1 | DUF905 family protein | - |
| BHT24_RS26500 () | 107249..107701 | - | 453 | WP_000290843.1 | single-stranded DNA-binding protein | - |
| BHT24_RS28090 () | 107727..107933 | - | 207 | WP_024190028.1 | hypothetical protein | - |
| BHT24_RS28095 () | 107846..108181 | - | 336 | WP_077816976.1 | hypothetical protein | - |
| BHT24_RS26520 () | 108344..108553 | - | 210 | WP_021512934.1 | hypothetical protein | - |
| BHT24_RS26525 () | 108579..109142 | - | 564 | WP_001315564.1 | class I SAM-dependent methyltransferase | - |
| BHT24_RS26530 () | 109190..110551 | - | 1362 | WP_000170724.1 | DUF3560 domain-containing protein | - |
| BHT24_RS26535 () | 110603..110833 | - | 231 | WP_000218642.1 | hypothetical protein | - |
| BHT24_RS27755 () | 111261..111506 | - | 246 | WP_012372797.1 | hypothetical protein | - |
| BHT24_RS26550 () | 111868..112059 | - | 192 | WP_001027519.1 | hypothetical protein | - |
| BHT24_RS26555 () | 112056..112478 | - | 423 | WP_000271751.1 | DUF1380 family protein | - |
| BHT24_RS26560 () | 112525..112827 | - | 303 | WP_077632858.1 | antirestriction protein | - |
| BHT24_RS27760 () | 113367..114137 | - | 771 | WP_001006209.1 | hypothetical protein | - |
| BHT24_RS26575 () | 114182..114616 | - | 435 | WP_000274502.1 | DUF1380 family protein | - |
| BHT24_RS26580 () | 114630..114851 | - | 222 | WP_001104879.1 | hypothetical protein | - |
| BHT24_RS26585 () | 114852..115535 | - | 684 | WP_000085871.1 | DNA methylase | - |
| BHT24_RS26590 () | 115611..115922 | - | 312 | WP_032141194.1 | hypothetical protein | - |
| BHT24_RS26595 () | 115919..116821 | - | 903 | WP_077632859.1 | DUF1281 domain-containing protein | - |
| BHT24_RS26605 () | 117559..118530 | - | 972 | WP_000817031.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| BHT24_RS26610 () | 118530..119696 | - | 1167 | WP_000772446.1 | Sporulation initiation inhibitor protein Soj | VF |
| BHT24_RS26615 () | 120284..121039 | - | 756 | WP_000852146.1 | replication initiation protein RepE | - |
| BHT24_RS26620 () | 121761..122567 | - | 807 | WP_000016970.1 | site-specific integrase | - |
| BHT24_RS26625 () | 122568..122873 | - | 306 | WP_001159871.1 | type II toxin-antitoxin system toxin CcdB | Toxin Detail |
| BHT24_RS26630 () | 122875..123093 | - | 219 | WP_000813630.1 | type II toxin-antitoxin system antitoxin CcdA | - |
| BHT24_RS26645 () | 123721..123951 | + | 231 | WP_001261286.1 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | - |
| BHT24_RS26650 () | 123948..124364 | + | 417 | WP_001034044.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| BHT24_RS26655 () | 124439..126004 | + | 1566 | WP_001128474.1 | AAA family ATPase | - |
| BHT24_RS26660 () | 125989..127011 | + | 1023 | WP_000361402.1 | helicase UvrD | - |
| BHT24_RS26670 () | 127265..127951 | - | 687 | Protein_151 | IS1 family transposase IS1S | Transposase |
| BHT24_RS26685 () | 129506..131707 | - | 2202 | WP_000973519.1 | Ferric aerobactin receptor | VF |
| BHT24_RS26690 () | 131789..133066 | - | 1278 | WP_000750130.1 | L-lysine N6-monooxygenase | VF |
| BHT24_RS26695 () | 133063..134805 | - | 1743 | WP_001015721.1 | Aerobactin synthase | VF |
| BHT24_RS26700 () | 134805..135752 | - | 948 | WP_000011908.1 | N(6)-hydroxylysine O-acetyltransferase | VF |
| BHT24_RS26705 () | 135753..137477 | - | 1725 | WP_000602863.1 | N(2)-citryl-N(6)-acetyl-N(6)-hydroxylysine synthase | VF |
| BHT24_RS26710 () | 137613..138806 | + | 1194 | WP_000095526.1 | MFS transporter | - |
| BHT24_RS26715 () | 139186..139566 | - | 381 | WP_001318207.1 | fluoride efflux transporter CrcB | - |
| BHT24_RS26725 () | 139907..140320 | - | 414 | Protein_160 | phosphopyruvate hydratase | - |
| BHT24_RS26730 () | 140318..140575 | + | 258 | Protein_161 | Tn3 family transposase | - |
| BHT24_RS26735 () | 140809..141666 | - | 858 | WP_000968139.1 | Manganese transport system membrane protein MntB | ARG |
| BHT24_RS26740 () | 141663..142520 | - | 858 | WP_001101723.1 | Manganese transport system membrane protein MntB | ARG |
| BHT24_RS26745 () | 142517..143344 | - | 828 | WP_000983710.1 | Iron(3+)-hydroxamate import ATP-binding protein FhuC | VF |
| BHT24_RS26750 () | 143344..144258 | - | 915 | WP_000949005.1 | Putative metal ABC transporter substrate-binding protein Hpf | VF |
| BHT24_RS26765 () | 144614..145300 | + | 687 | Protein_166 | IS1 family transposase IS1S | Transposase |
| BHT24_RS26770 () | 145480..145993 | - | 514 | Protein_167 | DUF4113 domain-containing protein | - |
| BHT24_RS28100 () | 146054..146158 | - | 105 | Protein_168 | AAA family ATPase | - |
| BHT24_RS26775 () | 146160..146483 | - | 324 | Protein_169 | IS21 family transposase IS21 | Transposase |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|