MGE detailed information
MGE type: Non-Mobilizable plasmid MGE length: 129154 bp
Accession: NZ_CP015140 Location: 1..129154 Organism: Escherichia coli strain Ecol_732 Replicon: plasmid pEC732_2
Accession: NZ_CP015140 Location: 1..129154 Organism: Escherichia coli strain Ecol_732 Replicon: plasmid pEC732_2
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| A4X18_RS26070 () | 1..837 | - | 837 | WP_000480972.1 | hypothetical protein | ARG |
| A4X18_RS26075 () | 837..1640 | - | 804 | WP_001082319.1 | Aminoglycoside 3'-phosphotransferase | ARG |
| A4X18_RS26080 () | 1701..2516 | - | 816 | WP_001043260.1 | Dihydropteroate synthase | ARG |
| A4X18_RS26085 () | 2824..3000 | - | 177 | Protein_3 | replication protein C | - |
| A4X18_RS26090 () | 3061..3765 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| A4X18_RS26095 () | 3887..4792 | + | 906 | WP_000219391.1 | hypothetical protein | ARG |
| A4X18_RS26100 () | 4789..6026 | + | 1238 | Protein_6 | MFS transporter | - |
| A4X18_RS26105 () | 6026..6610 | + | 585 | WP_001137892.1 | TetR family transcriptional regulator | - |
| A4X18_RS26110 () | 7103..7867 | - | 765 | WP_001389365.1 | IS6-like element IS6100 family transposase | - |
| A4X18_RS31315 () | 7985..8050 | - | 66 | Protein_9 | EAL domain-containing protein | - |
| A4X18_RS26115 () | 8094..8399 | - | 306 | WP_000130000.1 | hypothetical protein | Relaxase |
| A4X18_RS26120 () | 8410..9615 | - | 1206 | WP_000184001.1 | chromate efflux transporter | - |
| A4X18_RS26125 () | 9771..9974 | - | 204 | WP_000376616.1 | hypothetical protein | - |
| A4X18_RS26130 () | 10102..10941 | - | 840 | WP_000259031.1 | Dihydropteroate synthase | ARG |
| A4X18_RS26135 () | 10935..11282 | - | 348 | WP_000679427.1 | Multidrug transporter EmrE | ARG |
| A4X18_RS26140 () | 11488..12276 | - | 789 | WP_000503573.1 | Streptomycin 3''-adenylyltransferase | ARG |
| A4X18_RS26145 () | 12407..12880 | - | 474 | WP_001389366.1 | trimethoprim-resistant dihydrofolate reductase DfrA17 | - |
| A4X18_RS26150 () | 13038..13786 | + | 749 | Protein_17 | IS91 family transposase ISMno23 | Transposase |
| A4X18_RS26155 () | 13845..14549 | + | 705 | WP_001067858.1 | IS6 family transposase IS15DI | Transposase |
| A4X18_RS30910 () | 14599..14817 | - | 219 | Protein_19 | IS4 family transposase | - |
| A4X18_RS26165 () | 14832..15529 | - | 698 | Protein_20 | IS1 family transposase IS1R | Transposase |
| A4X18_RS31550 () | 15729..15842 | + | 114 | Protein_21 | IS6 family transposase | - |
| A4X18_RS26170 () | 15992..16150 | + | 159 | WP_000449408.1 | DsbA family protein | - |
| A4X18_RS26175 () | 16140..16646 | + | 507 | WP_000949452.1 | protein disulfide oxidoreductase | - |
| A4X18_RS26180 () | 16829..17644 | + | 816 | WP_012372823.1 | Na(+)-translocating NADH-quinone reductase subunit C | - |
| A4X18_RS26185 () | 17991..19877 | + | 1887 | WP_000118029.1 | FTR1 family iron permease | - |
| A4X18_RS26190 () | 19918..20445 | + | 528 | WP_000178050.1 | iron transporter | - |
| A4X18_RS26195 () | 20549..21928 | + | 1380 | WP_000119836.1 | DUF2318 domain-containing protein | - |
| A4X18_RS26200 () | 21931..23214 | + | 1284 | WP_000964653.1 | ABC transporter permease | - |
| A4X18_RS26205 () | 23204..24334 | + | 1131 | WP_000729218.1 | ABC transporter permease | - |
| A4X18_RS26210 () | 24339..25034 | + | 696 | WP_000117262.1 | Lipoprotein-releasing system ATP-binding protein LolD | VF |
| A4X18_RS26215 () | 25021..25506 | + | 486 | WP_001267176.1 | TlpA family protein disulfide reductase | - |
| A4X18_RS26220 () | 25531..26016 | + | 486 | WP_000874189.1 | hypothetical protein | - |
| A4X18_RS30920 () | 26138..26771 | + | 634 | Protein_33 | histidine-type phosphatase | - |
| A4X18_RS31555 () | 26921..27094 | - | 174 | Protein_34 | IS5 family transposase ISKpn26 | Transposase |
| A4X18_RS31560 () | 27095..27409 | - | 315 | Protein_35 | IS5 family transposase ISKpn26 | Transposase |
| A4X18_RS30925 () | 28082..28821 | - | 740 | Protein_36 | IS3 family transposase IS629 | Transposase |
| A4X18_RS26260 () | 28923..29183 | + | 261 | WP_000371882.1 | hypothetical protein | - |
| A4X18_RS26265 () | 29180..29689 | + | 510 | WP_000194542.1 | hypothetical protein | - |
| A4X18_RS26270 () | 29709..30056 | - | 348 | WP_000142452.1 | hypothetical protein | - |
| A4X18_RS26275 () | 30185..30520 | + | 336 | WP_001080732.1 | colicin transporter | - |
| A4X18_RS30935 () | 32092..32639 | + | 548 | Protein_41 | replication initiation protein | - |
| A4X18_RS26290 () | 32971..33846 | + | 876 | WP_001224623.1 | ChaN family lipoprotein | - |
| A4X18_RS26295 () | 33854..34630 | + | 777 | WP_000981091.1 | energy transducer TonB | - |
| A4X18_RS26300 () | 34799..37060 | + | 2262 | WP_001100763.1 | TonB-dependent receptor | - |
| A4X18_RS26305 () | 37129..38304 | + | 1176 | WP_001020413.1 | putative protein YncE | VF |
| A4X18_RS30945 () | 38827..39132 | - | 306 | Protein_46 | IS91 family transposase ISSbo1 | Transposase |
| A4X18_RS30950 () | 39158..39897 | + | 740 | Protein_47 | IS3 family transposase IS629 | Transposase |
| A4X18_RS26325 () | 40570..42078 | + | 1509 | WP_001189113.1 | group II intron reverse transcriptase/maturase | - |
| A4X18_RS26330 () | 42168..42551 | + | 384 | Protein_49 | IS3 family transposase IS629 | Transposase |
| A4X18_RS26335 () | 42580..42984 | + | 405 | WP_000839179.1 | IS66 family transposase ISEc22 | Transposase |
| A4X18_RS26340 () | 42981..43328 | + | 348 | WP_000612626.1 | IS66 family transposase ISKpn24 | Transposase |
| A4X18_RS26350 () | 43377..44322 | + | 946 | Protein_52 | IS66 family transposase ISEc8 | Transposase |
| A4X18_RS26355 () | 44408..45430 | + | 1023 | WP_001310017.1 | IS21 family transposase IS100kyp | Transposase |
| A4X18_RS26360 () | 45427..45963 | + | 537 | Protein_54 | IS21 family transposase IS100 | Transposase |
| A4X18_RS26365 () | 45994..47607 | - | 1614 | WP_000080195.1 | IS66 family transposase ISEc23 | Transposase |
| A4X18_RS26370 () | 47638..47988 | - | 351 | WP_000624722.1 | IS66 family transposase ISEc23 | Transposase |
| A4X18_RS26375 () | 47985..48410 | - | 426 | WP_000422741.1 | IS66 family transposase ISEc23 | Transposase |
| A4X18_RS26380 () | 48495..48749 | + | 255 | Protein_58 | IS21 family transposase IS100kyp | Transposase |
| A4X18_RS26385 () | 48817..49425 | + | 609 | Protein_59 | IS66 family transposase ISEc22 | Transposase |
| A4X18_RS26390 () | 49488..50279 | - | 792 | WP_000977394.1 | DUF4198 domain-containing protein | - |
| A4X18_RS26395 () | 50286..52256 | - | 1971 | WP_001298664.1 | Hemin receptor | VF |
| A4X18_RS26400 () | 52538..52974 | + | 437 | Protein_62 | IS3 family transposase IS2 | Transposase |
| A4X18_RS29350 () | 53499..53771 | + | 273 | WP_001322642.1 | Major pilu subunit operon regulatory protein PapB | VF |
| A4X18_RS30955 () | 54217..54392 | + | 176 | Protein_64 | IS3 family transposase | - |
| A4X18_RS26410 () | 54618..55787 | - | 1170 | WP_001072358.1 | hypothetical protein | - |
| A4X18_RS26415 () | 56154..56342 | + | 189 | WP_001309252.1 | hypothetical protein | - |
| A4X18_RS26420 () | 56463..57203 | + | 741 | WP_001066941.1 | tyrosine-type recombinase/integrase | - |
| A4X18_RS26425 () | 57488..58465 | - | 978 | WP_000361610.1 | RepB family plasmid replication initiator protein | - |
| A4X18_RS26440 () | 59251..59982 | + | 732 | WP_001617898.1 | hypothetical protein | - |
| A4X18_RS29360 () | 60351..60599 | - | 249 | Protein_70 | abortive infection family protein | - |
| A4X18_RS26445 () | 60657..61354 | + | 698 | Protein_71 | IS1 family transposase IS1R | Transposase |
| A4X18_RS26450 () | 61370..61699 | + | 330 | Protein_72 | TOBE domain-containing protein | - |
| A4X18_RS26455 () | 61808..62740 | - | 933 | WP_000081352.1 | homocysteine S-methyltransferase | - |
| A4X18_RS26460 () | 62727..64130 | - | 1404 | WP_001373486.1 | S-methylmethionine permease | - |
| A4X18_RS26465 () | 64374..65354 | + | 981 | WP_000019407.1 | IS5 family transposase IS5D | Transposase |
| A4X18_RS26470 () | 65582..65899 | + | 318 | WP_001513659.1 | hypothetical protein | - |
| A4X18_RS29370 () | 65849..66262 | - | 414 | Protein_77 | IS3 family transposase ISLad1 | Transposase |
| A4X18_RS26475 () | 66186..66545 | - | 360 | WP_001513660.1 | hypothetical protein | - |
| A4X18_RS26480 () | 66573..66752 | - | 180 | WP_001513661.1 | hypothetical protein | - |
| A4X18_RS26485 () | 66757..67137 | - | 381 | WP_001216034.1 | type II toxin-antitoxin system death-on-curing family toxin | Toxin Detail |
| A4X18_RS26490 () | 67137..67358 | - | 222 | WP_001190712.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin Detail |
| A4X18_RS26495 () | 67541..69097 | + | 1557 | WP_001617892.1 | type I restriction-modification system subunit M | - |
| A4X18_RS30965 () | 69094..69255 | + | 162 | Protein_83 | restriction endonuclease subunit S | - |
| A4X18_RS26505 () | 69311..70008 | + | 698 | Protein_84 | IS1 family transposase IS1G | Transposase |
| A4X18_RS26510 () | 70145..71077 | - | 933 | WP_000991832.1 | hypothetical protein | - |
| A4X18_RS26515 () | 71081..72076 | - | 996 | WP_000246636.1 | hypothetical protein | - |
| A4X18_RS26520 () | 72784..73002 | + | 219 | WP_000813634.1 | type II toxin-antitoxin system antitoxin CcdA | Antitoxin Detail |
| A4X18_RS26525 () | 73004..73309 | + | 306 | WP_001159868.1 | type II toxin-antitoxin system toxin CcdB | Toxin Detail |
| A4X18_RS26530 () | 73310..74116 | + | 807 | WP_000016982.1 | site-specific integrase | - |
| A4X18_RS26535 () | 74890..75645 | + | 756 | WP_000852146.1 | replication initiation protein RepE | - |
| A4X18_RS26540 () | 76233..77399 | + | 1167 | WP_000772446.1 | Sporulation initiation inhibitor protein Soj | VF |
| A4X18_RS26545 () | 77399..78370 | + | 972 | WP_000817036.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| A4X18_RS26550 () | 79237..80139 | + | 903 | WP_001348615.1 | DUF1281 domain-containing protein | - |
| A4X18_RS30265 () | 80143..80447 | + | 305 | Protein_94 | hypothetical protein | - |
| A4X18_RS26560 () | 80524..81207 | + | 684 | WP_000086185.1 | DNA methylase | - |
| A4X18_RS26565 () | 81208..81429 | + | 222 | WP_001104873.1 | hypothetical protein | - |
| A4X18_RS26570 () | 81443..81877 | + | 435 | WP_000274437.1 | DUF1380 family protein | - |
| A4X18_RS31320 () | 81928..82704 | + | 777 | WP_001753849.1 | hypothetical protein | - |
| A4X18_RS26580 () | 83244..83546 | + | 303 | WP_001671341.1 | antirestriction protein | - |
| A4X18_RS26585 () | 83593..84015 | + | 423 | WP_000271753.1 | DUF1380 family protein | - |
| A4X18_RS26590 () | 84012..84203 | + | 192 | WP_001027516.1 | hypothetical protein | - |
| A4X18_RS26595 () | 85238..85468 | + | 231 | WP_000218642.1 | hypothetical protein | - |
| A4X18_RS26600 () | 85520..86881 | + | 1362 | WP_000170714.1 | DUF3560 domain-containing protein | - |
| A4X18_RS26605 () | 86929..87492 | + | 564 | WP_001348621.1 | class I SAM-dependent methyltransferase | - |
| A4X18_RS31325 () | 87518..87784 | + | 267 | WP_032277138.1 | hypothetical protein | - |
| A4X18_RS31565 () | 87947..88282 | + | 336 | WP_013023883.1 | hypothetical protein | - |
| A4X18_RS26625 () | 88427..88966 | + | 540 | WP_000290841.1 | single-stranded DNA-binding protein | - |
| A4X18_RS26630 () | 89029..89262 | + | 234 | WP_000005990.1 | DUF905 family protein | - |
| A4X18_RS26635 () | 89328..91286 | + | 1959 | WP_000117179.1 | ParB/RepB/Spo0J family partition protein | - |
| A4X18_RS26640 () | 91341..91775 | + | 435 | WP_000845940.1 | conjugation system SOS inhibitor PsiB | - |
| A4X18_RS26645 () | 91772..92491 | + | 720 | WP_001276232.1 | plasmid SOS inhibition protein A | - |
| - () | 92503..92689 | + | 187 | NuclAT_0 | - | - |
| - () | 92503..92689 | + | 187 | NuclAT_0 | - | - |
| - () | 92503..92689 | + | 187 | NuclAT_0 | - | - |
| - () | 92503..92689 | + | 187 | NuclAT_0 | - | - |
| A4X18_RS30285 () | 92737..94106 | + | 1370 | WP_085947770.1 | IS3 family transposase IS150 | Transposase |
| - () | 94133..94173 | + | 41 | NuclAT_1 | - | Antitoxin Detail |
| - () | 94133..94173 | + | 41 | NuclAT_1 | - | Antitoxin Detail |
| - () | 94133..94173 | + | 41 | NuclAT_1 | - | Antitoxin Detail |
| - () | 94133..94173 | + | 41 | NuclAT_1 | - | Antitoxin Detail |
| A4X18_RS26665 () | 94217..94375 | + | 159 | WP_001312861.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| A4X18_RS31570 () | 94818..95153 | + | 336 | WP_013023876.1 | hypothetical protein | - |
| A4X18_RS31575 () | 95066..95272 | + | 207 | WP_000275859.1 | hypothetical protein | - |
| A4X18_RS26675 () | 95297..95584 | + | 288 | WP_000107535.1 | hypothetical protein | - |
| A4X18_RS26680 () | 95703..96218 | + | 516 | Protein_117 | DUF945 domain-containing protein | - |
| A4X18_RS26685 () | 96275..96972 | + | 698 | Protein_118 | IS1 family transposase IS1G | Transposase |
| A4X18_RS26690 () | 97020..97340 | + | 321 | WP_001348757.1 | conjugal transfer protein TrbA | - |
| A4X18_RS26695 () | 97467..97751 | + | 285 | WP_001617873.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| A4X18_RS26700 () | 97738..98283 | + | 546 | WP_000059829.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| A4X18_RS26705 () | 98213..98560 | + | 348 | WP_071571857.1 | P-type conjugative transfer protein TrbJ | - |
| A4X18_RS26710 () | 98508..98933 | + | 426 | WP_001348758.1 | F-type conjugal transfer protein TrbF | - |
| A4X18_RS26715 () | 98920..100293 | + | 1374 | WP_000944328.1 | conjugal transfer protein TraH | - |
| A4X18_RS26720 () | 100290..103109 | + | 2820 | WP_001007062.1 | conjugal transfer mating pair stabilization protein TraG | - |
| A4X18_RS26725 () | 103128..103625 | + | 498 | WP_000605862.1 | entry exclusion protein | - |
| A4X18_RS26730 () | 103657..104388 | + | 732 | WP_000850429.1 | complement resistance protein TraT | - |
| A4X18_RS26735 () | 104591..105370 | + | 780 | WP_000199914.1 | hypothetical protein | - |
| A4X18_RS26740 () | 105367..107592 | + | 2226 | WP_047605472.1 | type IV conjugative transfer system coupling protein TraD | - |
| A4X18_RS26745 () | 107592..112862 | + | 5271 | WP_001617867.1 | Multifunctional conjugation protein TraI | Relaxase |
| A4X18_RS26750 () | 112882..113628 | + | 747 | WP_000205718.1 | conjugal transfer pilus acetylase TraX | - |
| A4X18_RS26755 () | 113683..114243 | + | 561 | WP_000139341.1 | fertility inhibition protein FinO | - |
| A4X18_RS26760 () | 114374..114586 | + | 213 | WP_013023861.1 | hypothetical protein | - |
| A4X18_RS26765 () | 115145..115570 | + | 426 | WP_000422741.1 | IS66 family transposase ISEc23 | Transposase |
| A4X18_RS26770 () | 115567..115917 | + | 351 | WP_000624722.1 | IS66 family transposase ISEc23 | Transposase |
| A4X18_RS26775 () | 115948..117561 | + | 1614 | WP_000080195.1 | IS66 family transposase ISEc23 | Transposase |
| A4X18_RS26780 () | 117639..117925 | + | 287 | Protein_137 | DUF2726 domain-containing protein | - |
| - () | 117892..117952 | - | 61 | NuclAT_2 | - | Antitoxin Detail |
| - () | 117892..117952 | - | 61 | NuclAT_2 | - | Antitoxin Detail |
| - () | 117892..117952 | - | 61 | NuclAT_2 | - | Antitoxin Detail |
| - () | 117892..117952 | - | 61 | NuclAT_2 | - | Antitoxin Detail |
| A4X18_RS26785 () | 117997..118131 | + | 135 | WP_023144756.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| A4X18_RS26790 () | 118428..118682 | + | 255 | WP_000083850.1 | replication regulatory protein RepA | - |
| A4X18_RS31580 () | 118788..118922 | + | 135 | Protein_140 | protein CopA/IncA | - |
| A4X18_RS26795 () | 118919..118993 | + | 75 | WP_031943482.1 | RepA leader peptide Tap | - |
| A4X18_RS26800 () | 118986..119843 | + | 858 | WP_001617855.1 | incFII family plasmid replication initiator RepA | - |
| A4X18_RS26805 () | 120783..121436 | + | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| A4X18_RS31335 () | 121529..121786 | + | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| A4X18_RS26815 () | 121719..122120 | + | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| A4X18_RS29460 () | 122369..122784 | + | 416 | Protein_146 | IS1 family transposase | - |
| A4X18_RS26830 () | 122820..123365 | - | 546 | Protein_147 | Tn3 family transposase TnpA_Tn3 | Transposase |
| A4X18_RS26835 () | 123431..124135 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| A4X18_RS26845 () | 124449..125324 | + | 876 | WP_032277257.1 | Beta-lactamase CTX-M-97 | ARG |
| A4X18_RS26850 () | 125359..125721 | + | 363 | Protein_150 | transposase | - |
| A4X18_RS26855 () | 125781..126485 | + | 705 | WP_001067858.1 | IS6 family transposase IS15DI | Transposase |
| A4X18_RS26860 () | 126538..126870 | + | 333 | Protein_152 | EamA family transporter | - |
| A4X18_RS26865 () | 126902..128101 | - | 1200 | WP_000804064.1 | Tetracycline resistance protein, class C | ARG |
| A4X18_RS26870 () | 128207..128833 | + | 627 | WP_031606906.1 | tetracycline resistance transcriptional repressor TetR(A) | - |
| A4X18_RS26875 () | 128865..129101 | - | 237 | WP_042005022.1 | hypothetical protein | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|