MGE detailed information
MGE type: Conjugative plasmid MGE length: 130920 bp
Accession: NZ_CP015086 Location: 1..130920 Organism: Escherichia coli O25b:H4 Replicon: plasmid unnamed
Accession: NZ_CP015086 Location: 1..130920 Organism: Escherichia coli O25b:H4 Replicon: plasmid unnamed
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| WLH_RS27780 () | 545..736 | - | 192 | WP_000951934.1 | hypothetical protein | - |
| WLH_RS27785 () | 760..988 | + | 229 | Protein_2 | hypothetical protein | - |
| WLH_RS27790 () | 1039..2227 | + | 1189 | Protein_3 | DUF3883 domain-containing protein | - |
| WLH_RS27795 () | 2325..3654 | + | 1330 | Protein_4 | transposase | - |
| WLH_RS27800 () | 3620..4324 | + | 705 | WP_001067858.1 | IS6-like element IS26 family transposase | - |
| WLH_RS27810 () | 4377..4883 | + | 507 | Protein_6 | transposase | - |
| WLH_RS27815 () | 4892..5752 | + | 861 | WP_000493383.1 | EamA family transporter | - |
| WLH_RS27820 () | 5784..6983 | - | 1200 | WP_000804064.1 | Tetracycline resistance protein, class C | ARG |
| WLH_RS27825 () | 7089..7715 | + | 627 | WP_031606906.1 | tetracycline resistance transcriptional repressor TetR(A) | - |
| WLH_RS27830 () | 7747..7983 | - | 237 | WP_042005022.1 | hypothetical protein | - |
| WLH_RS27835 () | 8037..8873 | - | 837 | WP_000480972.1 | hypothetical protein | ARG |
| WLH_RS27840 () | 8873..9676 | - | 804 | WP_001082319.1 | Aminoglycoside 3'-phosphotransferase | ARG |
| WLH_RS27845 () | 9737..10552 | - | 816 | WP_001043260.1 | Dihydropteroate synthase | ARG |
| WLH_RS29570 () | 10740..11036 | - | 297 | Protein_14 | replication protein C | - |
| WLH_RS27865 () | 11097..11801 | + | 705 | WP_001067855.1 | IS6-like element IS26 family transposase | - |
| WLH_RS27875 () | 11923..12828 | + | 906 | WP_000219391.1 | hypothetical protein | ARG |
| WLH_RS27880 () | 12825..14063 | + | 1239 | WP_000004159.1 | MFS transporter | - |
| WLH_RS27885 () | 14063..14647 | + | 585 | WP_001137892.1 | TetR family transcriptional regulator | - |
| WLH_RS27900 () | 15140..15904 | - | 765 | WP_001389365.1 | IS6-like element IS6100 family transposase | - |
| WLH_RS29335 () | 16022..16087 | - | 66 | Protein_20 | EAL domain-containing protein | - |
| WLH_RS27910 () | 16131..16436 | - | 306 | WP_000130000.1 | hypothetical protein | Relaxase |
| WLH_RS27915 () | 16447..17652 | - | 1206 | WP_000184001.1 | chromate efflux transporter | - |
| WLH_RS27920 () | 17808..18011 | - | 204 | WP_000376616.1 | hypothetical protein | - |
| WLH_RS27930 () | 18139..18978 | - | 840 | WP_000259031.1 | Dihydropteroate synthase | ARG |
| WLH_RS27935 () | 18972..19319 | - | 348 | WP_000679427.1 | Multidrug transporter EmrE | ARG |
| WLH_RS27940 () | 19525..20313 | - | 789 | WP_000503573.1 | Streptomycin 3''-adenylyltransferase | ARG |
| WLH_RS27945 () | 20444..20917 | - | 474 | WP_001389366.1 | trimethoprim-resistant dihydrofolate reductase DfrA17 | - |
| WLH_RS27950 () | 21075..21620 | + | 546 | Protein_28 | IS91 family transposase ISAzo26 | Transposase |
| WLH_RS27955 () | 21685..22389 | + | 705 | WP_001067858.1 | IS6-like element IS26 family transposase | - |
| WLH_RS27965 () | 22847..24817 | - | 1971 | WP_001298664.1 | Hemin receptor | VF |
| WLH_RS27970 () | 25099..25535 | + | 437 | Protein_31 | IS3 family transposase IS2 | Transposase |
| WLH_RS27975 () | 26060..26332 | + | 273 | WP_001322642.1 | Major pilu subunit operon regulatory protein PapB | VF |
| WLH_RS27980 () | 26778..26953 | + | 176 | Protein_33 | IS3 family transposase | - |
| WLH_RS27985 () | 27179..28348 | - | 1170 | WP_001072358.1 | hypothetical protein | - |
| WLH_RS27990 () | 28715..28903 | + | 189 | WP_001309252.1 | hypothetical protein | - |
| WLH_RS27995 () | 29024..29764 | + | 741 | WP_033550837.1 | tyrosine-type recombinase/integrase | - |
| WLH_RS28000 () | 30049..31026 | - | 978 | WP_033550836.1 | RepB family plasmid replication initiator protein | - |
| WLH_RS28010 () | 31866..32507 | - | 642 | WP_033550835.1 | hypothetical protein | - |
| WLH_RS28020 () | 34623..34913 | + | 291 | WP_000538310.1 | hypothetical protein | - |
| WLH_RS28025 () | 34903..35724 | + | 822 | Protein_40 | nucleotide-binding protein | - |
| WLH_RS28030 () | 35754..37367 | - | 1614 | WP_000080195.1 | IS66 family transposase ISEc23 | Transposase |
| WLH_RS28035 () | 37398..37748 | - | 351 | WP_000624722.1 | IS66 family transposase ISEc23 | Transposase |
| WLH_RS28040 () | 37745..38170 | - | 426 | WP_000422741.1 | IS66 family transposase ISEc23 | Transposase |
| WLH_RS28045 () | 38392..40617 | - | 2226 | WP_000698737.1 | phage T7 exclusion protein | - |
| WLH_RS28050 () | 40619..41707 | - | 1089 | WP_000952217.1 | transcriptional repressor PifC | - |
| WLH_RS28055 () | 42287..42505 | + | 219 | WP_000813634.1 | type II toxin-antitoxin system antitoxin CcdA | Antitoxin Detail |
| WLH_RS28060 () | 42507..42812 | + | 306 | WP_001159868.1 | type II toxin-antitoxin system toxin CcdB | Toxin Detail |
| WLH_RS28065 () | 42813..43619 | + | 807 | WP_000016982.1 | site-specific integrase | - |
| WLH_RS28070 () | 44393..45148 | + | 756 | WP_000852146.1 | replication initiation protein RepE | - |
| WLH_RS28075 () | 45736..46902 | + | 1167 | WP_000772446.1 | Sporulation initiation inhibitor protein Soj | VF |
| WLH_RS28080 () | 46902..47873 | + | 972 | WP_000817036.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| WLH_RS28095 () | 48740..49642 | + | 903 | WP_077727434.1 | DUF1281 domain-containing protein | - |
| WLH_RS28100 () | 49646..49950 | + | 305 | Protein_53 | hypothetical protein | - |
| WLH_RS28105 () | 50027..50710 | + | 684 | WP_000086185.1 | DNA methylase | - |
| WLH_RS28110 () | 50711..50932 | + | 222 | WP_001104873.1 | hypothetical protein | - |
| WLH_RS28115 () | 50946..51380 | + | 435 | WP_000274437.1 | DUF1380 family protein | - |
| WLH_RS28120 () | 51431..52207 | + | 777 | WP_001753849.1 | hypothetical protein | - |
| WLH_RS28125 () | 52284..53396 | + | 1113 | WP_001300563.1 | IS4 family transposase IS421 | Transposase |
| WLH_RS28135 () | 54096..54398 | + | 303 | WP_001671341.1 | antirestriction protein | - |
| WLH_RS28140 () | 54445..54867 | + | 423 | WP_000271753.1 | DUF1380 family protein | - |
| WLH_RS28145 () | 54864..55055 | + | 192 | WP_001027516.1 | hypothetical protein | - |
| WLH_RS28155 () | 56090..56320 | + | 231 | WP_000218642.1 | hypothetical protein | - |
| WLH_RS28160 () | 56372..57733 | + | 1362 | WP_000170714.1 | DUF3560 domain-containing protein | - |
| WLH_RS28165 () | 57781..58344 | + | 564 | WP_001348621.1 | class I SAM-dependent methyltransferase | - |
| WLH_RS28170 () | 58370..58588 | + | 219 | WP_001496291.1 | hypothetical protein | - |
| WLH_RS29575 () | 58751..59086 | + | 336 | WP_013023883.1 | hypothetical protein | - |
| WLH_RS28195 () | 59883..61784 | + | 1902 | WP_000936285.1 | group II intron reverse transcriptase/maturase | - |
| WLH_RS28200 () | 61934..62431 | + | 498 | WP_042045560.1 | single-stranded DNA-binding protein | - |
| WLH_RS28205 () | 62494..62727 | + | 234 | WP_000005990.1 | DUF905 family protein | - |
| WLH_RS28210 () | 62793..64751 | + | 1959 | WP_042045562.1 | ParB/RepB/Spo0J family partition protein | - |
| WLH_RS28215 () | 64806..65240 | + | 435 | WP_000845949.1 | conjugation system SOS inhibitor PsiB | - |
| WLH_RS28220 () | 65237..65956 | + | 720 | WP_033550421.1 | plasmid SOS inhibition protein A | - |
| - () | 65968..66070 | + | 103 | NuclAT_1 | - | - |
| - () | 65968..66070 | + | 103 | NuclAT_1 | - | - |
| - () | 65968..66070 | + | 103 | NuclAT_1 | - | - |
| - () | 65968..66070 | + | 103 | NuclAT_1 | - | - |
| WLH_RS28225 () | 66116..67485 | + | 1370 | WP_085947770.1 | IS3 family transposase IS150 | Transposase |
| - () | 67512..67639 | + | 128 | NuclAT_0 | - | - |
| - () | 67512..67639 | + | 128 | NuclAT_0 | - | - |
| - () | 67512..67639 | + | 128 | NuclAT_0 | - | - |
| - () | 67512..67639 | + | 128 | NuclAT_0 | - | - |
| WLH_RS28235 () | 67683..67841 | + | 159 | WP_001312861.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| WLH_RS29580 () | 68284..68619 | + | 336 | WP_013023876.1 | hypothetical protein | - |
| WLH_RS29585 () | 68532..68738 | + | 207 | WP_000275859.1 | hypothetical protein | - |
| WLH_RS28255 () | 68763..69050 | + | 288 | WP_000107535.1 | hypothetical protein | - |
| WLH_RS28260 () | 69169..69990 | + | 822 | WP_001234469.1 | DUF945 domain-containing protein | - |
| WLH_RS28265 () | 70287..70889 | - | 603 | WP_000243712.1 | hypothetical protein | VF |
| WLH_RS28270 () | 71219..71602 | + | 384 | WP_001151566.1 | relaxosome protein TraM | - |
| WLH_RS28275 () | 71736..72413 | + | 678 | WP_001348626.1 | PAS domain-containing protein | - |
| WLH_RS28280 () | 72501..72728 | + | 228 | WP_001254388.1 | conjugal transfer relaxosome protein TraY | - |
| WLH_RS28285 () | 72762..73121 | + | 360 | WP_024210418.1 | type IV conjugative transfer system pilin TraA | - |
| WLH_RS28290 () | 73136..73447 | + | 312 | WP_000012107.1 | type IV conjugative transfer system protein TraL | - |
| WLH_RS28295 () | 73469..74035 | + | 567 | WP_000399791.1 | type IV conjugative transfer system protein TraE | - |
| WLH_RS28300 () | 74046..74750 | + | 705 | WP_148725207.1 | type-F conjugative transfer system secretin TraK | - |
| WLH_RS28305 () | 74750..76201 | + | 1452 | WP_000146687.1 | conjugal transfer protein TraB | - |
| WLH_RS28310 () | 76170..76706 | + | 537 | WP_104021966.1 | conjugal transfer protein TraP | - |
| WLH_RS28320 () | 76740..77437 | + | 698 | Protein_89 | IS1 family transposase IS1G | Transposase |
| WLH_RS28325 () | 77485..77805 | + | 321 | WP_001348757.1 | conjugal transfer protein TrbA | - |
| WLH_RS28330 () | 77932..78216 | + | 285 | WP_001617873.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| WLH_RS28335 () | 78203..78748 | + | 546 | WP_000059829.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| WLH_RS28340 () | 78678..79025 | + | 348 | WP_071571857.1 | P-type conjugative transfer protein TrbJ | - |
| WLH_RS28345 () | 78973..79398 | + | 426 | WP_001348758.1 | F-type conjugal transfer protein TrbF | - |
| WLH_RS28350 () | 79385..80758 | + | 1374 | WP_000944328.1 | conjugal transfer protein TraH | - |
| WLH_RS28355 () | 80755..83574 | + | 2820 | WP_001007062.1 | conjugal transfer mating pair stabilization protein TraG | - |
| WLH_RS28360 () | 83593..84090 | + | 498 | WP_000605862.1 | entry exclusion protein | - |
| WLH_RS28365 () | 84122..84853 | + | 732 | WP_000850429.1 | complement resistance protein TraT | - |
| WLH_RS28370 () | 85056..85835 | + | 780 | WP_000199914.1 | hypothetical protein | - |
| WLH_RS28375 () | 85832..88030 | + | 2199 | WP_024623315.1 | type IV conjugative transfer system coupling protein TraD | - |
| WLH_RS28380 () | 88030..93300 | + | 5271 | WP_042045338.1 | Multifunctional conjugation protein TraI | Relaxase |
| WLH_RS28385 () | 93320..94066 | + | 747 | WP_000205718.1 | conjugal transfer pilus acetylase TraX | - |
| WLH_RS28390 () | 94121..94681 | + | 561 | WP_000139341.1 | fertility inhibition protein FinO | - |
| WLH_RS28395 () | 94812..95024 | + | 213 | WP_013023861.1 | hypothetical protein | - |
| WLH_RS28405 () | 95537..95823 | + | 287 | Protein_105 | DUF2726 domain-containing protein | - |
| - () | 95790..95850 | - | 61 | NuclAT_2 | - | Antitoxin Detail |
| - () | 95790..95850 | - | 61 | NuclAT_2 | - | Antitoxin Detail |
| - () | 95790..95850 | - | 61 | NuclAT_2 | - | Antitoxin Detail |
| - () | 95790..95850 | - | 61 | NuclAT_2 | - | Antitoxin Detail |
| WLH_RS28410 () | 95895..96029 | + | 135 | WP_023144756.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| WLH_RS29100 () | 96326..96400 | + | 75 | WP_108401337.1 | hypothetical protein | - |
| WLH_RS28415 () | 96458..97204 | - | 747 | WP_001016257.1 | IS21 family transposase ISEc12 | Transposase |
| WLH_RS28420 () | 97219..98508 | - | 1290 | Protein_109 | IS21 family transposase ISEc12 | Transposase |
| WLH_RS28425 () | 98562..99266 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| WLH_RS28430 () | 99332..99844 | + | 513 | Protein_111 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| WLH_RS28435 () | 99868..100473 | - | 606 | WP_000509965.1 | Tn3 family transposase TnpR_Tn5403 | Transposase |
| WLH_RS28440 () | 100568..103465 | + | 2898 | WP_001553819.1 | Tn3 family transposase TnpA_Tn5403 | Transposase |
| WLH_RS28450 () | 103602..104003 | - | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| WLH_RS29340 () | 103936..104193 | - | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| WLH_RS28455 () | 104286..104939 | - | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| WLH_RS28465 () | 105879..106736 | - | 858 | WP_000130640.1 | incFII family plasmid replication initiator RepA | - |
| WLH_RS28470 () | 106729..106803 | - | 75 | WP_031943482.1 | RepA leader peptide Tap | - |
| WLH_RS29590 () | 106800..106934 | - | 135 | Protein_119 | protein CopA/IncA | - |
| WLH_RS28480 () | 107040..107255 | - | 216 | Protein_120 | replication regulatory protein RepA | - |
| WLH_RS28485 () | 107446..107703 | + | 258 | Protein_121 | IS21 family transposase ISEc12 | Transposase |
| WLH_RS28490 () | 107768..108472 | + | 705 | WP_001067855.1 | IS6-like element IS26 family transposase | - |
| WLH_RS28495 () | 108616..109170 | + | 555 | WP_063840321.1 | Aminoglycoside N(6')-acetyltransferase type 1 | ARG |
| WLH_RS28500 () | 109301..110131 | + | 831 | WP_001334766.1 | Beta-lactamase OXA-1 | ARG |
| WLH_RS28505 () | 110269..110709 | + | 441 | Protein_125 | CatB-related O-acetyltransferase | - |
| WLH_RS28510 () | 110763..111467 | - | 705 | WP_001067855.1 | IS6-like element IS26 family transposase | - |
| WLH_RS28520 () | 111589..112293 | - | 705 | WP_001067855.1 | IS6-like element IS26 family transposase | - |
| WLH_RS28525 () | 112358..114601 | - | 2244 | Protein_128 | Tn3 family transposase TnpA_Tn3 | Transposase |
| WLH_RS28530 () | 114615..114947 | + | 333 | WP_001393253.1 | WbuC family cupin fold metalloprotein | - |
| WLH_RS28535 () | 114994..115869 | - | 876 | WP_000239590.1 | Beta-lactamase CTX-M-1 | ARG |
| WLH_RS28540 () | 116125..117387 | - | 1263 | WP_000608644.1 | IS1380 family transposase ISEcp1 | Transposase |
| WLH_RS28545 () | 117593..117787 | - | 195 | Protein_132 | Tn3 family transposase TnpA_Tn3 | Transposase |
| WLH_RS28550 () | 117951..118277 | + | 327 | Protein_133 | Tn3 family transposase TnpR_Tn3 | Transposase |
| WLH_RS28560 () | 118329..119033 | - | 705 | WP_001067858.1 | IS6-like element IS26 family transposase | - |
| WLH_RS28565 () | 119097..119543 | + | 447 | Protein_135 | tunicamycin resistance protein | - |
| WLH_RS28570 () | 120025..120216 | - | 192 | WP_000951934.1 | hypothetical protein | - |
| WLH_RS28575 () | 120240..120467 | + | 228 | WP_000248278.1 | hypothetical protein | - |
| WLH_RS28580 () | 120518..121654 | + | 1137 | WP_000080860.1 | DUF3883 domain-containing protein | - |
| WLH_RS28585 () | 121769..123131 | + | 1363 | Protein_139 | transposase | - |
| WLH_RS28590 () | 123097..123801 | + | 705 | WP_001067858.1 | IS6-like element IS26 family transposase | - |
| WLH_RS28600 () | 123854..124360 | + | 507 | Protein_141 | transposase | - |
| WLH_RS28605 () | 124369..125229 | + | 861 | WP_000493383.1 | EamA family transporter | - |
| WLH_RS28610 () | 125261..126461 | - | 1201 | Protein_143 | Tetracycline resistance protein, class C | ARG |
| WLH_RS28615 () | 126567..127192 | + | 626 | Protein_144 | tetracycline resistance transcriptional repressor TetR(A) | - |
| WLH_RS28620 () | 127224..127460 | - | 237 | WP_042005022.1 | hypothetical protein | - |
| WLH_RS28625 () | 127514..128338 | - | 825 | WP_104021968.1 | hypothetical protein | ARG |
| WLH_RS28630 () | 128351..129151 | - | 801 | WP_114140747.1 | Aminoglycoside 3'-phosphotransferase | ARG |
| WLH_RS28635 () | 129216..130034 | - | 819 | Protein_148 | Dihydropteroate synthase | ARG |
| WLH_RS28650 () | 130322..130520 | - | 199 | Protein_149 | replication protein C | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|