MGE detailed information
MGE type: Conjugative plasmid MGE length: 111851 bp
Accession: NZ_CP015070 Location: 1..111851 Organism: Escherichia coli strain Ecol_743 Replicon: plasmid pEC743_1
Accession: NZ_CP015070 Location: 1..111851 Organism: Escherichia coli strain Ecol_743 Replicon: plasmid pEC743_1
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| A4R39_RS23865 () | 1..3117 | - | 3117 | WP_001553854.1 | HsdR family type I site-specific deoxyribonuclease | - |
| A4R39_RS23870 () | 3239..4522 | - | 1284 | WP_001617890.1 | restriction endonuclease subunit S | - |
| A4R39_RS23875 () | 4519..6075 | - | 1557 | WP_001617892.1 | type I restriction-modification system subunit M | - |
| A4R39_RS23880 () | 6258..6479 | + | 222 | WP_001190712.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin Detail |
| A4R39_RS23885 () | 6479..6859 | + | 381 | WP_001216034.1 | type II toxin-antitoxin system death-on-curing family toxin | Toxin Detail |
| A4R39_RS23890 () | 6864..7043 | + | 180 | WP_001513661.1 | hypothetical protein | - |
| A4R39_RS23895 () | 7071..7430 | + | 360 | WP_001513660.1 | hypothetical protein | - |
| A4R39_RS23900 () | 7354..7767 | + | 414 | Protein_7 | IS3 family transposase ISLad1 | Transposase |
| A4R39_RS23905 () | 7717..8034 | - | 318 | WP_001513659.1 | hypothetical protein | - |
| A4R39_RS23910 () | 8262..9242 | - | 981 | WP_000019407.1 | IS5 family transposase IS5D | Transposase |
| A4R39_RS23915 () | 9486..10889 | + | 1404 | WP_001373486.1 | S-methylmethionine permease | - |
| A4R39_RS23920 () | 10876..11808 | + | 933 | WP_000081352.1 | homocysteine S-methyltransferase | - |
| A4R39_RS23925 () | 11917..12246 | - | 330 | Protein_12 | TOBE domain-containing protein | - |
| A4R39_RS23930 () | 12262..12959 | - | 698 | Protein_13 | IS1 family transposase IS1R | Transposase |
| A4R39_RS27295 () | 13017..13265 | + | 249 | Protein_14 | abortive infection family protein | - |
| A4R39_RS23935 () | 13634..14365 | - | 732 | WP_001617898.1 | hypothetical protein | - |
| A4R39_RS23950 () | 15151..16128 | + | 978 | WP_000361610.1 | RepB family plasmid replication initiator protein | - |
| A4R39_RS23955 () | 16413..17153 | - | 741 | WP_001066941.1 | tyrosine-type recombinase/integrase | - |
| A4R39_RS23960 () | 17274..17462 | - | 189 | WP_001309252.1 | hypothetical protein | - |
| A4R39_RS23965 () | 17829..18998 | + | 1170 | WP_001072358.1 | hypothetical protein | - |
| A4R39_RS28680 () | 19224..19399 | - | 176 | Protein_20 | IS3 family transposase | - |
| A4R39_RS27305 () | 19845..20117 | - | 273 | WP_001322642.1 | Major pilu subunit operon regulatory protein PapB | VF |
| A4R39_RS23975 () | 20642..21078 | - | 437 | Protein_22 | IS3 family transposase IS2 | Transposase |
| A4R39_RS23980 () | 21360..23330 | + | 1971 | WP_001298664.1 | Hemin receptor | VF |
| A4R39_RS23985 () | 23337..24128 | + | 792 | WP_000977394.1 | DUF4198 domain-containing protein | - |
| A4R39_RS23990 () | 24191..24799 | - | 609 | Protein_25 | IS66 family transposase ISEc22 | Transposase |
| A4R39_RS23995 () | 24867..25649 | - | 783 | WP_001300609.1 | IS21 family transposase IS100kyp | Transposase |
| A4R39_RS24000 () | 25646..26668 | - | 1023 | WP_001310017.1 | IS21 family transposase IS100kyp | Transposase |
| A4R39_RS24005 () | 26754..27699 | - | 946 | Protein_28 | IS66 family transposase ISEc8 | Transposase |
| A4R39_RS24015 () | 27748..28095 | - | 348 | WP_000612626.1 | IS66 family transposase ISKpn24 | Transposase |
| A4R39_RS24020 () | 28092..28496 | - | 405 | WP_000839179.1 | IS66 family transposase ISEc22 | Transposase |
| A4R39_RS24025 () | 28525..28908 | - | 384 | Protein_31 | IS3 family transposase IS629 | Transposase |
| A4R39_RS24030 () | 28998..30506 | - | 1509 | WP_001189113.1 | group II intron reverse transcriptase/maturase | - |
| A4R39_RS28685 () | 31179..31918 | - | 740 | Protein_33 | IS3 family transposase IS629 | Transposase |
| A4R39_RS28690 () | 31944..32249 | + | 306 | Protein_34 | IS91 family transposase ISSbo1 | Transposase |
| A4R39_RS24055 () | 32772..33947 | - | 1176 | WP_001020413.1 | putative protein YncE | VF |
| A4R39_RS24060 () | 34016..36277 | - | 2262 | WP_001100763.1 | TonB-dependent receptor | - |
| A4R39_RS24065 () | 36404..37101 | - | 698 | Protein_37 | IS1 family transposase IS1X2 | Transposase |
| A4R39_RS24070 () | 37350..37751 | - | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| A4R39_RS28700 () | 37684..37941 | - | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| A4R39_RS24080 () | 38034..38687 | - | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| A4R39_RS24085 () | 39627..40484 | - | 858 | WP_001617855.1 | incFII family plasmid replication initiator RepA | - |
| A4R39_RS27340 () | 40477..40551 | - | 75 | WP_031943482.1 | RepA leader peptide Tap | - |
| A4R39_RS28965 () | 40548..40682 | - | 135 | Protein_43 | protein CopA/IncA | - |
| A4R39_RS24090 () | 40788..41042 | - | 255 | WP_000083850.1 | replication regulatory protein RepA | - |
| A4R39_RS24095 () | 41339..41473 | - | 135 | WP_023144756.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| - () | 41518..41578 | + | 61 | NuclAT_2 | - | Antitoxin Detail |
| - () | 41518..41578 | + | 61 | NuclAT_2 | - | Antitoxin Detail |
| - () | 41518..41578 | + | 61 | NuclAT_2 | - | Antitoxin Detail |
| - () | 41518..41578 | + | 61 | NuclAT_2 | - | Antitoxin Detail |
| A4R39_RS27350 () | 41545..41831 | - | 287 | Protein_46 | DUF2726 domain-containing protein | - |
| A4R39_RS24100 () | 41909..43522 | - | 1614 | WP_000080195.1 | IS66 family transposase ISEc23 | Transposase |
| A4R39_RS24105 () | 43553..43903 | - | 351 | WP_000624722.1 | IS66 family transposase ISEc23 | Transposase |
| A4R39_RS24110 () | 43900..44325 | - | 426 | WP_000422741.1 | IS66 family transposase ISEc23 | Transposase |
| A4R39_RS24115 () | 44884..45096 | - | 213 | WP_013023861.1 | hypothetical protein | - |
| A4R39_RS24120 () | 45227..45787 | - | 561 | WP_000139341.1 | fertility inhibition protein FinO | - |
| A4R39_RS24125 () | 45842..46588 | - | 747 | WP_000205718.1 | conjugal transfer pilus acetylase TraX | - |
| A4R39_RS24130 () | 46608..51878 | - | 5271 | WP_001617867.1 | Multifunctional conjugation protein TraI | Relaxase |
| A4R39_RS24135 () | 51878..54094 | - | 2217 | WP_023356304.1 | type IV conjugative transfer system coupling protein TraD | - |
| A4R39_RS24140 () | 54091..54870 | - | 780 | WP_000199914.1 | hypothetical protein | - |
| A4R39_RS24145 () | 55073..55804 | - | 732 | WP_000850429.1 | complement resistance protein TraT | - |
| A4R39_RS24150 () | 55836..56333 | - | 498 | WP_000605862.1 | entry exclusion protein | - |
| A4R39_RS24155 () | 56352..59171 | - | 2820 | WP_001007062.1 | conjugal transfer mating pair stabilization protein TraG | - |
| A4R39_RS24160 () | 59168..60541 | - | 1374 | WP_000944328.1 | conjugal transfer protein TraH | - |
| A4R39_RS24165 () | 60528..60953 | - | 426 | WP_001348758.1 | F-type conjugal transfer protein TrbF | - |
| A4R39_RS24170 () | 60901..61248 | - | 348 | WP_071571857.1 | P-type conjugative transfer protein TrbJ | - |
| A4R39_RS24175 () | 61178..61723 | - | 546 | WP_000059829.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| A4R39_RS24180 () | 61710..61994 | - | 285 | WP_001617873.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| A4R39_RS24185 () | 62121..62441 | - | 321 | WP_001348757.1 | conjugal transfer protein TrbA | - |
| A4R39_RS24190 () | 62489..63186 | - | 698 | Protein_65 | IS1 family transposase IS1G | Transposase |
| A4R39_RS24195 () | 63341..64321 | - | 981 | WP_000019450.1 | IS5 family transposase ISKpn26 | Transposase |
| A4R39_RS24200 () | 64451..65194 | - | 744 | WP_001030401.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| A4R39_RS24205 () | 65187..65444 | - | 258 | WP_000864347.1 | conjugal transfer protein TrbE | - |
| A4R39_RS24210 () | 65471..67321 | - | 1851 | WP_000821866.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| A4R39_RS24215 () | 67318..67956 | - | 639 | WP_001080259.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| A4R39_RS24220 () | 67965..68270 | - | 306 | WP_000224413.1 | hypothetical protein | - |
| A4R39_RS24225 () | 68300..69292 | - | 993 | WP_000830190.1 | conjugal transfer pilus assembly protein TraU | - |
| A4R39_RS24230 () | 69289..69921 | - | 633 | WP_001203727.1 | type-F conjugative transfer system protein TraW | - |
| A4R39_RS24235 () | 69918..70304 | - | 387 | WP_000214084.1 | type-F conjugative transfer system protein TrbI | - |
| A4R39_RS24240 () | 70301..72928 | - | 2628 | WP_063131966.1 | type IV secretion system protein TraC | - |
| A4R39_RS27370 () | 73088..73309 | - | 222 | WP_001278694.1 | conjugal transfer protein TraR | - |
| A4R39_RS24245 () | 73444..73959 | - | 516 | WP_000809886.1 | type IV conjugative transfer system lipoprotein TraV | - |
| A4R39_RS24250 () | 73959..74318 | - | 360 | WP_001617876.1 | conjugal transfer protein TrbD | - |
| A4R39_RS24255 () | 74257..74844 | - | 588 | WP_013023871.1 | conjugal transfer protein TraP | - |
| A4R39_RS24260 () | 74813..76264 | - | 1452 | WP_000146687.1 | conjugal transfer protein TraB | - |
| A4R39_RS24265 () | 76264..76968 | - | 705 | WP_148725207.1 | type-F conjugative transfer system secretin TraK | - |
| A4R39_RS24270 () | 76979..77545 | - | 567 | WP_000399791.1 | type IV conjugative transfer system protein TraE | - |
| A4R39_RS24275 () | 77567..77878 | - | 312 | WP_000012107.1 | type IV conjugative transfer system protein TraL | - |
| A4R39_RS24280 () | 77883..78245 | - | 363 | WP_000338606.1 | type IV conjugative transfer system pilin TraA | - |
| A4R39_RS24285 () | 78279..78506 | - | 228 | WP_001254388.1 | conjugal transfer relaxosome protein TraY | - |
| A4R39_RS24290 () | 78594..79271 | - | 678 | WP_001348626.1 | PAS domain-containing protein | - |
| A4R39_RS24295 () | 79405..79788 | - | 384 | WP_001151566.1 | relaxosome protein TraM | - |
| A4R39_RS24300 () | 80119..80721 | + | 603 | WP_000243712.1 | hypothetical protein | VF |
| A4R39_RS24305 () | 81018..81839 | - | 822 | WP_001234469.1 | DUF945 domain-containing protein | - |
| A4R39_RS24310 () | 81958..82245 | - | 288 | WP_000107535.1 | hypothetical protein | - |
| A4R39_RS28110 () | 82270..82476 | - | 207 | WP_000275859.1 | hypothetical protein | - |
| A4R39_RS28970 () | 82389..82724 | - | 336 | WP_013023876.1 | hypothetical protein | - |
| A4R39_RS24320 () | 83167..83325 | - | 159 | WP_001312861.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| - () | 83369..83409 | - | 41 | NuclAT_1 | - | Antitoxin Detail |
| - () | 83369..83409 | - | 41 | NuclAT_1 | - | Antitoxin Detail |
| - () | 83369..83409 | - | 41 | NuclAT_1 | - | Antitoxin Detail |
| - () | 83369..83409 | - | 41 | NuclAT_1 | - | Antitoxin Detail |
| - () | 84853..85039 | - | 187 | NuclAT_0 | - | - |
| - () | 84853..85039 | - | 187 | NuclAT_0 | - | - |
| - () | 84853..85039 | - | 187 | NuclAT_0 | - | - |
| - () | 84853..85039 | - | 187 | NuclAT_0 | - | - |
| A4R39_RS24340 () | 85051..85770 | - | 720 | WP_001276232.1 | plasmid SOS inhibition protein A | - |
| A4R39_RS24345 () | 85767..86201 | - | 435 | WP_000845940.1 | conjugation system SOS inhibitor PsiB | - |
| A4R39_RS24350 () | 86256..88214 | - | 1959 | WP_000117179.1 | ParB/RepB/Spo0J family partition protein | - |
| A4R39_RS24355 () | 88280..88513 | - | 234 | WP_000005990.1 | DUF905 family protein | - |
| A4R39_RS24360 () | 88576..89073 | - | 498 | WP_042045560.1 | single-stranded DNA-binding protein | - |
| A4R39_RS24365 () | 89223..91124 | - | 1902 | WP_000936285.1 | group II intron reverse transcriptase/maturase | - |
| A4R39_RS28140 () | 92419..92655 | - | 237 | WP_032153960.1 | hypothetical protein | - |
| A4R39_RS24380 () | 92681..93244 | - | 564 | WP_001348621.1 | class I SAM-dependent methyltransferase | - |
| A4R39_RS24385 () | 93291..94652 | - | 1362 | WP_000170714.1 | DUF3560 domain-containing protein | - |
| A4R39_RS24390 () | 94704..94934 | - | 231 | WP_000218642.1 | hypothetical protein | - |
| A4R39_RS24395 () | 95969..96160 | - | 192 | WP_001027516.1 | hypothetical protein | - |
| A4R39_RS24400 () | 96157..96579 | - | 423 | WP_000271753.1 | DUF1380 family protein | - |
| A4R39_RS24405 () | 96626..96928 | - | 303 | WP_001671341.1 | antirestriction protein | - |
| A4R39_RS28725 () | 97468..98244 | - | 777 | WP_001753849.1 | hypothetical protein | - |
| A4R39_RS24420 () | 98295..98729 | - | 435 | WP_000274437.1 | DUF1380 family protein | - |
| A4R39_RS24425 () | 98743..98964 | - | 222 | WP_001104873.1 | hypothetical protein | - |
| A4R39_RS24430 () | 98965..99648 | - | 684 | WP_000086185.1 | DNA methylase | - |
| A4R39_RS28150 () | 99725..100029 | - | 305 | Protein_112 | hypothetical protein | - |
| A4R39_RS24440 () | 100033..100935 | - | 903 | WP_001348615.1 | DUF1281 domain-containing protein | - |
| A4R39_RS24445 () | 101802..102773 | - | 972 | WP_000817036.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| A4R39_RS24450 () | 102773..103939 | - | 1167 | WP_000772446.1 | Sporulation initiation inhibitor protein Soj | VF |
| A4R39_RS27420 () | 104624..105321 | + | 698 | Protein_116 | IS1 family transposase IS1R | Transposase |
| A4R39_RS24460 () | 105328..106059 | - | 732 | Protein_117 | replication initiation protein RepE | - |
| A4R39_RS24465 () | 106833..107639 | - | 807 | WP_000016982.1 | site-specific integrase | - |
| A4R39_RS24470 () | 107640..107945 | - | 306 | WP_001159868.1 | type II toxin-antitoxin system toxin CcdB | - |
| A4R39_RS24475 () | 107947..108165 | - | 219 | WP_000813634.1 | type II toxin-antitoxin system antitoxin CcdA | - |
| A4R39_RS24480 () | 108873..109868 | + | 996 | WP_000246636.1 | hypothetical protein | - |
| A4R39_RS24485 () | 109872..110804 | + | 933 | WP_000991832.1 | hypothetical protein | - |
| A4R39_RS24490 () | 110941..111638 | - | 698 | Protein_123 | IS1 family transposase IS1G | Transposase |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|