MGE detailed information
MGE type: Conjugative plasmid MGE length: 162720 bp
Accession: NZ_CP010192 Location: 1..162720 Organism: Escherichia coli strain M8 Replicon: plasmid A
Accession: NZ_CP010192 Location: 1..162720 Organism: Escherichia coli strain M8 Replicon: plasmid A
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| RG57_RS25000 () | 111..569 | - | 459 | Protein_0 | IS200-IS605 family transposase IS200F | Transposase |
| RG57_RS25010 () | 758..1720 | - | 963 | WP_077898678.1 | ParB/RepB/Spo0J family partition protein | - |
| RG57_RS25015 () | 1717..2922 | - | 1206 | WP_000817642.1 | Plasmid partition protein A | VF |
| RG57_RS25025 () | 3293..3508 | + | 216 | WP_077898679.1 | hypothetical protein | - |
| RG57_RS25035 () | 3682..3933 | + | 252 | WP_001132895.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin Detail |
| RG57_RS25040 () | 3930..4217 | + | 288 | WP_001270421.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin Detail |
| RG57_RS25045 () | 4219..4630 | + | 412 | Protein_6 | DDE-type integrase/transposase/recombinase | - |
| RG57_RS25060 () | 5275..6252 | + | 978 | WP_001355280.1 | RepB family plasmid replication initiator protein | - |
| RG57_RS25065 () | 6537..7277 | - | 741 | WP_001066926.1 | IS91 family transposase ISMno23 | Transposase |
| RG57_RS25070 () | 7398..7559 | - | 162 | WP_073535365.1 | transcriptional regulator | - |
| RG57_RS26945 () | 7871..8823 | - | 953 | Protein_10 | IS630 family transposase ISSpu2 | Transposase |
| RG57_RS25095 () | 9286..9789 | - | 504 | WP_000450723.1 | hypothetical protein | - |
| RG57_RS25100 () | 10581..11057 | + | 477 | WP_000072543.1 | hypothetical protein | VF |
| RG57_RS25105 () | 11060..12538 | + | 1479 | WP_000150697.1 | hypothetical protein | VF |
| RG57_RS25110 () | 12587..13066 | + | 480 | WP_073535366.1 | type VI secretion protein | - |
| RG57_RS25115 () | 13074..13496 | + | 423 | WP_073535310.1 | lysozyme family protein | - |
| RG57_RS25120 () | 13489..15291 | + | 1803 | WP_073535311.1 | type VI secretion system baseplate subunit TssF | - |
| RG57_RS25125 () | 15282..16214 | + | 933 | WP_073535312.1 | type VI secretion system baseplate subunit TssG | - |
| RG57_RS25130 () | 16227..18209 | + | 1983 | WP_001307039.1 | type VI secretion system tip protein VgrG | - |
| RG57_RS25135 () | 18220..18687 | + | 468 | WP_000133489.1 | hypothetical protein | - |
| RG57_RS25140 () | 18697..18996 | + | 300 | WP_032246098.1 | PAAR domain-containing protein | - |
| RG57_RS25145 () | 19000..20076 | + | 1077 | WP_001307038.1 | hypothetical protein | VF |
| RG57_RS25150 () | 20084..20626 | + | 543 | WP_000152800.1 | type VI secretion lipoprotein TssJ | - |
| RG57_RS25155 () | 20645..22009 | + | 1365 | WP_073535313.1 | type VI secretion system baseplate subunit TssK | - |
| RG57_RS25165 () | 22381..22995 | + | 615 | WP_077898682.1 | DotU family type IV/VI secretion system protein | - |
| RG57_RS25170 () | 23002..26406 | + | 3405 | WP_073535314.1 | type VI secretion protein | - |
| RG57_RS25175 () | 26410..28941 | + | 2532 | WP_073535315.1 | Protein ClpV1 | VF |
| RG57_RS25180 () | 29634..30773 | + | 1140 | WP_000359995.1 | type VI secretion system ImpA family N-terminal domain-containing protein | - |
| RG57_RS25185 () | 31273..31863 | + | 591 | WP_000819279.1 | hypothetical protein | VF |
| RG57_RS27440 () | 32145..32267 | + | 123 | Protein_29 | IS1 family transposase | - |
| RG57_RS26960 () | 32531..33127 | + | 597 | WP_077787744.1 | hypothetical protein | - |
| RG57_RS25195 () | 33136..33608 | - | 473 | Protein_31 | IS3 family transposase IS1351 | Transposase |
| RG57_RS25200 () | 33622..33756 | + | 135 | Protein_32 | transposase | - |
| RG57_RS26965 () | 34342..34563 | + | 222 | WP_024179415.1 | hypothetical protein | - |
| RG57_RS27815 () | 34777..34869 | - | 93 | Protein_34 | IS21 family transposase ISEc12 | Transposase |
| RG57_RS25215 () | 35117..35323 | + | 207 | Protein_35 | alpha/beta hydrolase | - |
| RG57_RS26970 () | 35570..35933 | + | 364 | Protein_36 | helix-turn-helix domain containing protein | - |
| RG57_RS27445 () | 35937..36149 | + | 213 | Protein_37 | IS21 family transposase | - |
| RG57_RS25230 () | 36156..36524 | - | 369 | WP_032246119.1 | hypothetical protein | - |
| RG57_RS25235 () | 37425..37532 | - | 108 | Protein_39 | IS3 family transposase | - |
| RG57_RS25240 () | 37535..38034 | - | 500 | Protein_40 | transposase | - |
| RG57_RS25245 () | 38075..38266 | + | 192 | Protein_41 | recombinase family protein | - |
| RG57_RS25255 () | 38529..38810 | - | 282 | WP_073535368.1 | hypothetical protein | - |
| RG57_RS25260 () | 38917..39192 | - | 276 | WP_000421276.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin Detail |
| RG57_RS25265 () | 39192..39476 | - | 285 | WP_001307030.1 | ribbon-helix-helix protein, CopG family | Antitoxin Detail |
| RG57_RS25270 () | 39713..39838 | - | 126 | Protein_45 | IS66 family transposase IS682 | Transposase |
| RG57_RS25275 () | 39835..40269 | - | 435 | WP_073535316.1 | IS66 family transposase ISEc43 | Transposase |
| RG57_RS26980 () | 40839..41251 | - | 413 | Protein_47 | transposase | - |
| RG57_RS25285 () | 42412..46341 | + | 3930 | WP_073535317.1 | Serine protease EspC | VF |
| RG57_RS25290 () | 46424..46716 | + | 293 | Protein_49 | hypothetical protein | VF |
| RG57_RS25295 () | 47311..47811 | - | 501 | WP_073535318.1 | helix-turn-helix transcriptional regulator | - |
| RG57_RS25300 () | 47840..48322 | - | 483 | WP_046201729.1 | DNA-directed RNA polymerase sigma-70 factor | - |
| RG57_RS25305 () | 48444..50693 | - | 2250 | WP_077898692.1 | hemolysin activation protein | - |
| RG57_RS25310 () | 51621..52269 | - | 649 | Protein_53 | hypothetical protein | - |
| RG57_RS25315 () | 52474..53721 | - | 1248 | WP_073535319.1 | HlyD family efflux transporter periplasmic adaptor subunit | - |
| RG57_RS25320 () | 53781..55928 | - | 2148 | WP_073535320.1 | Toxin RTX-I translocation ATP-binding protein | VF |
| RG57_RS25325 () | 55953..57194 | - | 1242 | WP_034173814.1 | TolC family protein | - |
| RG57_RS25330 () | 57257..57550 | - | 294 | WP_072035418.1 | Major pilu subunit operon regulatory protein PapB | VF |
| RG57_RS27455 () | 58844..59033 | - | 190 | Protein_58 | site-specific integrase | - |
| RG57_RS25345 () | 59539..59754 | + | 216 | Protein_59 | TIGR00156 family protein | - |
| RG57_RS25350 () | 59785..60203 | - | 419 | Protein_60 | Tn3 family transposase | - |
| RG57_RS25355 () | 60672..61517 | - | 846 | WP_052734128.1 | AraC family transcriptional regulator | - |
| RG57_RS25360 () | 61914..62465 | + | 552 | WP_071886272.1 | type 1 fimbrial protein | - |
| RG57_RS25365 () | 62572..63291 | + | 720 | WP_024179409.1 | Chaperone protein FocC | VF |
| RG57_RS25370 () | 63313..65823 | + | 2511 | WP_077898685.1 | Outer membrane usher protein FimD | VF |
| RG57_RS25375 () | 65833..66744 | + | 912 | WP_139108882.1 | fimbrial protein | - |
| RG57_RS25380 () | 66826..67134 | + | 309 | WP_073535322.1 | Cyclic di-GMP phosphodiesterase PdeL | VF |
| RG57_RS25390 () | 67625..68098 | - | 474 | Protein_67 | hypothetical protein | - |
| RG57_RS25400 () | 68368..78060 | - | 9693 | WP_073535323.1 | tRNA nuclease CdiA | VF |
| RG57_RS25405 () | 78073..79845 | - | 1773 | WP_073535324.1 | Hemolysin transporter protein ShlB | VF |
| RG57_RS25410 () | 80068..80316 | - | 249 | Protein_70 | DNA-binding protein | - |
| RG57_RS25415 () | 80402..80836 | + | 435 | WP_073535316.1 | IS66 family transposase ISEc43 | Transposase |
| RG57_RS25420 () | 80833..81138 | + | 306 | WP_073535325.1 | IS66 family transposase IS682 | Transposase |
| RG57_RS26985 () | 81214..82757 | + | 1544 | Protein_73 | IS66 family transposase | - |
| RG57_RS25440 () | 82788..83050 | + | 263 | Protein_74 | hypothetical protein | - |
| RG57_RS25445 () | 83152..84161 | - | 1010 | Protein_75 | IS3 family transposase IS3F | Transposase |
| RG57_RS25455 () | 84244..84828 | - | 585 | WP_073535326.1 | lipopolysaccharide core heptose(II)-phosphate phosphatase | - |
| RG57_RS25460 () | 85039..85818 | - | 780 | WP_073535327.1 | EAL domain-containing protein | - |
| RG57_RS25465 () | 85982..86935 | - | 954 | WP_073535328.1 | hypothetical protein | - |
| RG57_RS25470 () | 87027..87596 | - | 570 | WP_000615957.1 | hypothetical protein | - |
| RG57_RS25475 () | 87604..88122 | - | 519 | WP_073535329.1 | fimbrial protein | - |
| RG57_RS25480 () | 88109..88801 | - | 693 | WP_001044793.1 | Chaperone protein FaeE | VF |
| RG57_RS25485 () | 88794..91199 | - | 2406 | WP_073535330.1 | Outer membrane usher protein FimD | VF |
| RG57_RS25490 () | 91285..91803 | - | 519 | WP_073535331.1 | hypothetical protein | VF |
| RG57_RS25495 () | 91916..92188 | - | 273 | WP_073535332.1 | Major pilu subunit operon regulatory protein PapB | VF |
| RG57_RS26990 () | 92749..93043 | - | 295 | Protein_85 | IS256 family transposase ISSoEn2 | Transposase |
| RG57_RS26995 () | 93296..94050 | + | 755 | Protein_86 | AraC family transcriptional regulator | - |
| RG57_RS25510 () | 94209..94505 | - | 297 | WP_001307005.1 | Cyclic di-GMP phosphodiesterase PdeL | VF |
| RG57_RS25515 () | 94616..97717 | - | 3102 | WP_073535333.1 | putative autotransporter | VF |
| RG57_RS25520 () | 97701..98930 | - | 1230 | WP_073535334.1 | autotransporter strand-loop-strand O-heptosyltransferase | - |
| RG57_RS25530 () | 99733..100134 | - | 402 | WP_149025817.1 | type II toxin-antitoxin system PemK/MazF family toxin | - |
| RG57_RS27470 () | 100067..100324 | - | 258 | WP_073535337.1 | antitoxin | - |
| RG57_RS25555 () | 101338..102195 | - | 858 | WP_073535341.1 | incFII family plasmid replication initiator RepA | - |
| RG57_RS25560 () | 102188..102262 | - | 75 | WP_001365705.1 | RepA leader peptide Tap | - |
| RG57_RS25570 () | 102491..102754 | - | 264 | WP_000078112.1 | replication regulatory protein RepA | - |
| RG57_RS27630 () | 103101..103187 | - | 87 | WP_187415237.1 | Hok/Gef family protein | - |
| RG57_RS25580 () | 103448..104557 | - | 1110 | WP_073535342.1 | N-acetylneuraminate epimerase | - |
| RG57_RS25585 () | 104567..105277 | - | 711 | WP_000748140.1 | N-acetylneuraminic acid channel protein | - |
| RG57_RS25590 () | 105331..106152 | - | 822 | WP_000529634.1 | alpha/beta hydrolase | - |
| RG57_RS25595 () | 106168..107634 | - | 1467 | WP_001307003.1 | MFS transporter | - |
| RG57_RS25600 () | 107704..108579 | - | 876 | WP_001307002.1 | N-acetylmannosamine kinase | - |
| RG57_RS25605 () | 108639..109538 | - | 900 | WP_001307001.1 | N-acetylneuraminate lyase | - |
| RG57_RS25610 () | 109675..110760 | - | 1086 | WP_000745949.1 | hypothetical protein | - |
| RG57_RS25615 () | 110830..111558 | + | 729 | WP_073535343.1 | transcriptional regulator NanR | - |
| RG57_RS25620 () | 111583..112467 | - | 885 | WP_073535344.1 | alpha/beta hydrolase | - |
| RG57_RS27820 () | 112614..112715 | + | 102 | Protein_105 | transposase | - |
| RG57_RS25635 () | 113333..113893 | - | 561 | WP_073535345.1 | fertility inhibition protein FinO | - |
| RG57_RS25640 () | 113948..114682 | - | 735 | WP_077898688.1 | type-F conjugative transfer system pilin acetylase TraX | - |
| RG57_RS25645 () | 114705..115136 | - | 432 | WP_000451345.1 | hypothetical protein | - |
| RG57_RS25650 () | 115186..120456 | - | 5271 | WP_073535346.1 | Multifunctional conjugation protein TraI | Relaxase |
| RG57_RS25655 () | 120456..122645 | - | 2190 | WP_001360340.1 | type IV conjugative transfer system coupling protein TraD | - |
| RG57_RS25660 () | 122897..123628 | - | 732 | WP_000850424.1 | complement resistance protein TraT | - |
| RG57_RS25665 () | 123660..124172 | - | 513 | WP_077898693.1 | surface exclusion protein | - |
| RG57_RS25670 () | 124187..127009 | - | 2823 | WP_073535347.1 | conjugal transfer mating pair stabilization protein TraG | - |
| RG57_RS25675 () | 127006..128379 | - | 1374 | WP_073535348.1 | conjugal transfer protein TraH | - |
| RG57_RS25680 () | 128379..128741 | - | 363 | WP_071829681.1 | P-type conjugative transfer protein TrbJ | - |
| RG57_RS25685 () | 128671..129216 | - | 546 | WP_044804936.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| RG57_RS25690 () | 129203..129484 | - | 282 | WP_000549795.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| RG57_RS25695 () | 129600..130343 | - | 744 | WP_001030378.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| RG57_RS25700 () | 130336..130593 | - | 258 | WP_000864341.1 | conjugal transfer protein TrbE | - |
| RG57_RS25705 () | 130620..132470 | - | 1851 | WP_073535349.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| RG57_RS25710 () | 132467..133105 | - | 639 | WP_044804935.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| RG57_RS25715 () | 133114..133419 | - | 306 | WP_073535350.1 | hypothetical protein | - |
| RG57_RS25720 () | 133449..134441 | - | 993 | WP_024227463.1 | conjugal transfer pilus assembly protein TraU | - |
| RG57_RS25725 () | 134438..135070 | - | 633 | WP_001203720.1 | type-F conjugative transfer system protein TraW | - |
| RG57_RS25730 () | 135067..135453 | - | 387 | WP_000214082.1 | type-F conjugative transfer system protein TrbI | - |
| RG57_RS25735 () | 135450..138077 | - | 2628 | WP_073535351.1 | type IV secretion system protein TraC | - |
| RG57_RS25740 () | 138237..138458 | - | 222 | WP_001278689.1 | conjugal transfer protein TraR | - |
| RG57_RS25745 () | 138593..139108 | - | 516 | WP_000809838.1 | type IV conjugative transfer system lipoprotein TraV | - |
| RG57_RS25750 () | 139105..139356 | - | 252 | WP_001038342.1 | conjugal transfer protein TrbG | - |
| RG57_RS25755 () | 139349..139702 | - | 354 | WP_071829680.1 | conjugal transfer protein TrbD | - |
| RG57_RS25760 () | 139656..140246 | - | 591 | WP_000002783.1 | conjugal transfer protein TraP | - |
| RG57_RS25765 () | 140236..141663 | - | 1428 | WP_024214918.1 | conjugal transfer protein TraB | - |
| RG57_RS25770 () | 141663..142391 | - | 729 | WP_001700184.1 | type-F conjugative transfer system secretin TraK | - |
| RG57_RS25775 () | 142378..142944 | - | 567 | WP_000399792.1 | type IV conjugative transfer system protein TraE | - |
| RG57_RS25780 () | 142966..143277 | - | 312 | WP_073519963.1 | type IV conjugative transfer system protein TraL | - |
| RG57_RS25785 () | 143292..143651 | - | 360 | WP_073535352.1 | type IV conjugative transfer system pilin TraA | - |
| RG57_RS25790 () | 143685..143912 | - | 228 | WP_032246093.1 | conjugal transfer relaxosome protein TraY | - |
| RG57_RS25795 () | 144006..144692 | - | 687 | WP_073535353.1 | PAS domain-containing protein | - |
| RG57_RS25800 () | 144883..145266 | - | 384 | WP_073535354.1 | relaxosome protein TraM | - |
| RG57_RS25810 () | 145552..146199 | + | 648 | WP_149025818.1 | hypothetical protein | VF |
| RG57_RS25815 () | 146496..147317 | - | 822 | WP_001234469.1 | DUF945 domain-containing protein | - |
| RG57_RS25820 () | 147440..147727 | - | 288 | WP_000107535.1 | hypothetical protein | - |
| RG57_RS27005 () | 147729..147926 | + | 198 | Protein_143 | hypothetical protein | - |
| RG57_RS25835 () | 148374..148532 | - | 159 | WP_001312861.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| - () | 148576..148800 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - () | 148576..148800 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - () | 148576..148800 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - () | 148576..148800 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| RG57_RS27635 () | 148612..148800 | + | 189 | WP_001496304.1 | hypothetical protein | - |
| RG57_RS25845 () | 148812..149531 | - | 720 | WP_001276234.1 | plasmid SOS inhibition protein A | - |
| RG57_RS25850 () | 149528..149962 | - | 435 | Protein_147 | conjugation system SOS inhibitor PsiB | - |
| RG57_RS25855 () | 150017..151975 | - | 1959 | WP_073535355.1 | ParB/RepB/Spo0J family partition protein | - |
| RG57_RS25860 () | 152034..152267 | - | 234 | WP_073535356.1 | DUF905 domain-containing protein | - |
| RG57_RS25865 () | 152323..152850 | - | 528 | WP_000290793.1 | single-stranded DNA-binding protein | - |
| RG57_RS25880 () | 153323..153589 | - | 267 | WP_072254135.1 | hypothetical protein | - |
| RG57_RS25890 () | 153741..154304 | - | 564 | WP_001311069.1 | class I SAM-dependent methyltransferase | - |
| RG57_RS25895 () | 154351..155712 | - | 1362 | WP_073535357.1 | DUF3560 domain-containing protein | - |
| RG57_RS25900 () | 155764..155994 | - | 231 | WP_027663199.1 | hypothetical protein | - |
| RG57_RS27825 () | 156512..157067 | + | 556 | Protein_155 | hypothetical protein | - |
| RG57_RS25920 () | 157037..157228 | - | 192 | WP_001027516.1 | hypothetical protein | - |
| RG57_RS25925 () | 157225..157647 | - | 423 | WP_001546488.1 | DUF1380 family protein | - |
| RG57_RS25930 () | 157694..157996 | - | 303 | WP_072126845.1 | antirestriction protein | - |
| RG57_RS27500 () | 158533..159303 | - | 771 | WP_001006225.1 | hypothetical protein | - |
| RG57_RS25945 () | 159348..159782 | - | 435 | WP_073535359.1 | DUF1380 family protein | - |
| RG57_RS25950 () | 159796..160017 | - | 222 | WP_073535360.1 | hypothetical protein | - |
| RG57_RS25955 () | 160018..160701 | - | 684 | WP_073535361.1 | DNA methylase | - |
| RG57_RS25960 () | 160778..161083 | - | 306 | WP_073535362.1 | hypothetical protein | - |
| RG57_RS25970 () | 161363..162625 | + | 1263 | Protein_164 | translesion error-prone DNA polymerase V subunit UmuC | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|