MGE detailed information
MGE type: Conjugative plasmid MGE length: 130968 bp
Accession: NZ_AP023221 Location: 1..130968 Organism: Escherichia coli strain M505 Replicon: plasmid pM505-a
Accession: NZ_AP023221 Location: 1..130968 Organism: Escherichia coli strain M505 Replicon: plasmid pM505-a
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| EPG46_RS23755 () | 61..5331 | - | 5271 | WP_039023145.1 | Multifunctional conjugation protein TraI | Relaxase |
| EPG46_RS23760 () | 5413..5640 | + | 228 | WP_039023146.1 | toxin-antitoxin system antitoxin VapB | Antitoxin Detail |
| EPG46_RS23765 () | 5640..6038 | + | 399 | WP_039023147.1 | tRNA(fMet)-specific endonuclease VapC | Toxin Detail |
| EPG46_RS23770 () | 6047..8245 | - | 2199 | WP_061856952.1 | type IV conjugative transfer system coupling protein TraD | - |
| EPG46_RS23775 () | 8498..9229 | - | 732 | WP_000850422.1 | complement resistance protein TraT | - |
| EPG46_RS23780 () | 9292..10867 | - | 1576 | Protein_5 | IS66 family transposase | - |
| EPG46_RS23785 () | 10887..11235 | - | 349 | Protein_6 | IS66 family transposase ISCro1 | Transposase |
| EPG46_RS23790 () | 11251..11916 | - | 666 | Protein_7 | IS66 family transposase ISCro1 | Transposase |
| EPG46_RS23795 () | 11977..12474 | - | 498 | WP_000605862.1 | entry exclusion protein | - |
| EPG46_RS23800 () | 12493..13860 | - | 1368 | Protein_9 | conjugal transfer protein TraG | - |
| EPG46_RS23805 () | 13941..14345 | + | 405 | WP_000839179.1 | IS66 family transposase ISEc22 | Transposase |
| EPG46_RS23810 () | 14342..14689 | + | 348 | WP_000612626.1 | IS66 family transposase ISKpn24 | Transposase |
| EPG46_RS23815 () | 14739..16279 | + | 1541 | Protein_12 | IS66 family transposase ISEc22 | Transposase |
| EPG46_RS23820 () | 16320..17777 | - | 1458 | Protein_13 | conjugal transfer mating pair stabilization protein TraG | - |
| EPG46_RS23825 () | 17774..19147 | - | 1374 | WP_039023150.1 | conjugal transfer protein TraH | - |
| EPG46_RS23830 () | 19147..19509 | - | 363 | WP_071550055.1 | P-type conjugative transfer protein TrbJ | - |
| EPG46_RS23835 () | 19439..19984 | - | 546 | WP_039052470.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| EPG46_RS23840 () | 19971..20255 | - | 285 | WP_000624110.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| EPG46_RS23845 () | 20374..20721 | - | 348 | WP_001287894.1 | conjugal transfer protein TrbA | - |
| EPG46_RS23850 () | 20737..21480 | - | 744 | WP_001030376.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| EPG46_RS23855 () | 21473..21730 | - | 258 | WP_039023152.1 | conjugal transfer protein TrbE | - |
| EPG46_RS23860 () | 21757..23544 | - | 1788 | WP_039052473.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| EPG46_RS23865 () | 23855..24235 | - | 381 | WP_039052469.1 | hypothetical protein | - |
| EPG46_RS23870 () | 24232..24870 | - | 639 | WP_039052468.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| EPG46_RS23875 () | 24879..25871 | - | 993 | WP_000830835.1 | conjugal transfer pilus assembly protein TraU | - |
| EPG46_RS23880 () | 25868..26500 | - | 633 | WP_039052467.1 | type-F conjugative transfer system protein TraW | - |
| EPG46_RS23885 () | 26497..26883 | - | 387 | WP_000099693.1 | type-F conjugative transfer system protein TrbI | - |
| EPG46_RS23890 () | 26880..29507 | - | 2628 | WP_001064265.1 | type IV secretion system protein TraC | - |
| EPG46_RS23895 () | 29667..29888 | - | 222 | WP_001278685.1 | conjugal transfer protein TraR | - |
| EPG46_RS23900 () | 30023..30539 | - | 517 | Protein_29 | type IV conjugative transfer system lipoprotein TraV | - |
| EPG46_RS23905 () | 30536..30787 | - | 252 | WP_039052465.1 | conjugal transfer protein TrbG | - |
| EPG46_RS23910 () | 30780..31148 | - | 369 | WP_071550054.1 | conjugal transfer protein TrbD | - |
| EPG46_RS23915 () | 31087..31668 | - | 582 | WP_052273600.1 | conjugal transfer protein TraP | - |
| EPG46_RS23920 () | 31637..33090 | - | 1454 | Protein_33 | conjugal transfer protein TraB | - |
| EPG46_RS23925 () | 33090..34370 | - | 1281 | WP_176488921.1 | type-F conjugative transfer system secretin TraK | - |
| EPG46_RS23930 () | 34392..34703 | - | 312 | WP_000012106.1 | type IV conjugative transfer system protein TraL | - |
| EPG46_RS23935 () | 34708..35070 | - | 363 | WP_039052460.1 | type IV conjugative transfer system pilin TraA | - |
| EPG46_RS23940 () | 35103..35498 | - | 396 | WP_001309237.1 | conjugal transfer relaxosome protein TraY | - |
| EPG46_RS23945 () | 35597..36286 | - | 690 | WP_061856953.1 | conjugal transfer transcriptional regulator TraJ | - |
| EPG46_RS23950 () | 36473..36856 | - | 384 | WP_061856954.1 | relaxosome protein TraM | - |
| EPG46_RS23955 () | 37176..37778 | + | 603 | WP_077878371.1 | hypothetical protein | VF |
| EPG46_RS23960 () | 38074..38895 | - | 822 | WP_061856956.1 | DUF945 domain-containing protein | - |
| EPG46_RS23965 () | 39014..39301 | - | 288 | WP_061856957.1 | hypothetical protein | - |
| EPG46_RS23970 () | 39602..39930 | + | 329 | Protein_43 | hypothetical protein | - |
| EPG46_RS23975 () | 39921..40052 | + | 132 | Protein_44 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| EPG46_RS23980 () | 40132..40832 | - | 701 | Protein_45 | IS1 family transposase IS1A | Transposase |
| EPG46_RS23985 () | 41005..41622 | + | 618 | Protein_46 | ISL3 family transposase ISEc38 | Transposase |
| EPG46_RS23990 () | 42086..43093 | - | 1008 | WP_001232702.1 | LacI family DNA-binding transcriptional regulator | - |
| EPG46_RS23995 () | 43119..44528 | - | 1410 | WP_039052598.1 | sucrose-6-phosphate hydrolase | - |
| EPG46_RS24000 () | 44528..45898 | - | 1371 | WP_000344915.1 | sucrose-specific PTS transporter subunit IIBC | - |
| EPG46_RS24005 () | 45959..47476 | - | 1518 | WP_039052597.1 | carbohydrate porin | - |
| EPG46_RS24010 () | 47644..48564 | - | 921 | WP_039052596.1 | aminoimidazole riboside kinase | - |
| EPG46_RS24015 () | 48925..49277 | + | 353 | Protein_52 | pilus protein | - |
| EPG46_RS24020 () | 49258..49821 | - | 564 | WP_001377760.1 | class I SAM-dependent methyltransferase | - |
| EPG46_RS24025 () | 49869..51230 | - | 1362 | WP_039052595.1 | DUF3560 domain-containing protein | - |
| EPG46_RS24030 () | 51282..51511 | - | 230 | Protein_55 | hypothetical protein | - |
| EPG46_RS24040 () | 52464..52655 | - | 192 | WP_001027495.1 | hypothetical protein | - |
| EPG46_RS24045 () | 52704..53006 | - | 303 | WP_077878372.1 | antirestriction protein | - |
| EPG46_RS24050 () | 53545..53994 | - | 450 | Protein_58 | hypothetical protein | - |
| EPG46_RS24055 () | 54171..54527 | + | 357 | WP_039052614.1 | hypothetical protein | - |
| EPG46_RS24060 () | 54565..55218 | + | 654 | WP_039052615.1 | hypothetical protein | - |
| EPG46_RS24065 () | 55332..56030 | + | 699 | WP_001390273.1 | IS1 family transposase IS1A | Transposase |
| EPG46_RS24070 () | 56324..56644 | + | 321 | WP_000562370.1 | antibiotic biosynthesis monooxygenase | - |
| EPG46_RS24075 () | 56637..57023 | + | 387 | WP_000460651.1 | hypothetical protein | - |
| EPG46_RS24080 () | 57031..57717 | + | 687 | WP_001284954.1 | winged helix-turn-helix domain-containing protein | - |
| EPG46_RS24085 () | 57695..58318 | - | 624 | WP_000088605.1 | Tetracycline repressor protein class B from transposon Tn10 | VF |
| EPG46_RS24090 () | 58400..59605 | + | 1206 | WP_001089068.1 | Tetracycline resistance protein, class B | ARG |
| EPG46_RS24095 () | 59718..60311 | - | 594 | WP_000428546.1 | tetracyline resistance-associated transcriptional repressor TetC | - |
| EPG46_RS24100 () | 60444..60815 | + | 372 | WP_035689358.1 | Transposon Tn10 TetD protein | VF |
| EPG46_RS24105 () | 60825..62042 | - | 1218 | WP_061856962.1 | IS4 family transposase IS10R | Transposase |
| EPG46_RS24110 () | 62064..63187 | + | 1124 | Protein_70 | IS3-like element ISSen4 family transposase | - |
| EPG46_RS24115 () | 64170..64946 | + | 777 | WP_039052454.1 | hypothetical protein | - |
| EPG46_RS24120 () | 64948..67212 | + | 2265 | WP_039052447.1 | UvrD-helicase domain-containing protein | - |
| EPG46_RS24125 () | 67555..68535 | + | 981 | WP_039052448.1 | IS5 family transposase ISKpn26 | Transposase |
| EPG46_RS24130 () | 68949..70039 | + | 1091 | Protein_74 | translesion error-prone DNA polymerase V subunit UmuC | - |
| EPG46_RS24135 () | 70044..70436 | - | 393 | WP_039052449.1 | plasmid partitioning/stability family protein | - |
| EPG46_RS24140 () | 70441..71412 | - | 972 | WP_039052450.1 | plasmid segregation protein parM | - |
| EPG46_RS24145 () | 71641..72285 | + | 645 | WP_000633913.1 | AAA family ATPase | - |
| EPG46_RS24150 () | 72279..72554 | + | 276 | WP_000239529.1 | hypothetical protein | - |
| EPG46_RS24155 () | 72692..73192 | - | 501 | Protein_79 | IS91 family transposase ISAzo26 | Transposase |
| EPG46_RS24160 () | 73174..73413 | - | 240 | WP_157916581.1 | resolvase | - |
| EPG46_RS24165 () | 73520..74128 | - | 609 | WP_039052451.1 | hypothetical protein | - |
| EPG46_RS24170 () | 74198..74548 | - | 351 | WP_039052452.1 | hypothetical protein | - |
| EPG46_RS24175 () | 75226..76221 | + | 996 | WP_000246635.1 | hypothetical protein | - |
| EPG46_RS24180 () | 76225..77157 | + | 933 | WP_000991831.1 | hypothetical protein | - |
| EPG46_RS24185 () | 77450..77635 | + | 186 | WP_001586223.1 | hypothetical protein | - |
| EPG46_RS24190 () | 77636..78538 | + | 903 | WP_024187432.1 | hypothetical protein | - |
| EPG46_RS24195 () | 78540..79409 | + | 870 | WP_001586225.1 | hypothetical protein | - |
| EPG46_RS24200 () | 79466..81031 | - | 1566 | WP_001586226.1 | ATP-binding protein | - |
| EPG46_RS24205 () | 81318..81830 | + | 513 | WP_001586228.1 | hypothetical protein | - |
| EPG46_RS24210 () | 81864..82997 | - | 1134 | WP_000545985.1 | DUF3800 domain-containing protein | - |
| EPG46_RS24215 () | 83164..83936 | - | 773 | Protein_91 | hypothetical protein | - |
| EPG46_RS24220 () | 83965..84450 | - | 486 | WP_001403958.1 | hypothetical protein | - |
| EPG46_RS24225 () | 84841..87462 | + | 2622 | WP_001586230.1 | hypothetical protein | - |
| EPG46_RS24230 () | 87661..87891 | + | 231 | WP_001261274.1 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | Antitoxin Detail |
| EPG46_RS24235 () | 87980..88255 | + | 276 | WP_001403920.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| EPG46_RS24240 () | 88260..88477 | - | 218 | Protein_96 | transposase | - |
| EPG46_RS24245 () | 88478..89008 | - | 531 | WP_000348883.1 | GNAT family N-acetyltransferase | Toxin Detail |
| EPG46_RS24250 () | 89012..89281 | - | 270 | WP_001275013.1 | DUF1778 domain-containing protein | Antitoxin Detail |
| EPG46_RS24255 () | 90169..91158 | + | 990 | WP_123002471.1 | RepB family plasmid replication initiator protein | - |
| EPG46_RS24260 () | 91481..92221 | - | 741 | WP_001586233.1 | tyrosine-type recombinase/integrase | - |
| EPG46_RS24265 () | 92342..92524 | - | 183 | WP_042004909.1 | hypothetical protein | - |
| EPG46_RS24270 () | 92591..92752 | - | 162 | WP_001440647.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| EPG46_RS24275 () | 92868..93136 | - | 269 | Protein_103 | type II toxin-antitoxin system ParD family antitoxin | - |
| EPG46_RS24280 () | 93432..94172 | - | 741 | WP_029702141.1 | IS91 family transposase ISMno23 | Transposase |
| EPG46_RS24285 () | 94212..94909 | - | 698 | Protein_105 | IS1 family transposase IS1X2 | Transposase |
| EPG46_RS24290 () | 95125..95574 | - | 450 | WP_029702172.1 | hypothetical protein | - |
| EPG46_RS24295 () | 96101..96624 | + | 524 | Protein_107 | IS1 family transposase | - |
| EPG46_RS24300 () | 96716..96997 | - | 282 | Protein_108 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| EPG46_RS24305 () | 97253..98584 | - | 1332 | Protein_109 | group II intron reverse transcriptase/maturase | - |
| EPG46_RS24310 () | 99201..100063 | - | 863 | Protein_110 | Beta-lactamase TEM | ARG |
| EPG46_RS24315 () | 100246..100803 | - | 558 | WP_001235713.1 | Tn3 family transposase TnpR_Tn3 | Transposase |
| EPG46_RS24320 () | 100967..101161 | + | 195 | Protein_112 | Tn3 family transposase TnpA_Tn3 | Transposase |
| EPG46_RS24325 () | 101367..102629 | + | 1263 | WP_000608644.1 | IS1380 family transposase ISEcp1 | Transposase |
| EPG46_RS24330 () | 102885..103760 | + | 876 | WP_000239590.1 | Beta-lactamase CTX-M-1 | ARG |
| EPG46_RS24335 () | 103807..104139 | - | 333 | WP_001393253.1 | WbuC family cupin fold metalloprotein | - |
| EPG46_RS24340 () | 104153..106950 | + | 2798 | Protein_116 | Tn3 family transposase TnpA_Tn3 | Transposase |
| EPG46_RS24345 () | 106993..108008 | - | 1016 | Protein_117 | IS3 family transposase ISEc36 | Transposase |
| EPG46_RS24350 () | 108403..109059 | + | 657 | WP_001516695.1 | Pentapeptide repeat protein | ARG |
| EPG46_RS24355 () | 109378..109806 | - | 429 | Protein_119 | Tn3 family transposase TnpR_ISMex22 | Transposase |
| EPG46_RS24360 () | 109839..111230 | - | 1392 | WP_001493761.1 | ISKra4 family transposase ISKpn19 | Transposase |
| EPG46_RS24365 () | 111267..111839 | - | 573 | WP_001493762.1 | Tn3 family transposase TnpR_ISPa40 | Transposase |
| EPG46_RS24370 () | 111976..112566 | - | 591 | WP_012477564.1 | plasmid pRiA4b ORF-3 family protein | - |
| EPG46_RS24375 () | 112656..112817 | - | 162 | Protein_123 | type II toxin-antitoxin system mRNA interferase RelE | - |
| EPG46_RS24380 () | 112817..113056 | - | 240 | WP_000534857.1 | type II toxin-antitoxin system antitoxin RelB | - |
| EPG46_RS24385 () | 113437..115434 | + | 1998 | WP_005032116.1 | choline BCCT transporter BetT | - |
| EPG46_RS24390 () | 115498..116775 | + | 1278 | WP_000625667.1 | DUF2254 domain-containing protein | - |
| EPG46_RS24395 () | 116916..117725 | - | 810 | WP_000161640.1 | hypothetical protein | - |
| EPG46_RS24400 () | 117948..118652 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| EPG46_RS24405 () | 118718..119266 | + | 549 | Protein_129 | Tn3 family transposase | - |
| EPG46_RS24410 () | 119302..119717 | - | 416 | Protein_130 | IS1 family transposase | - |
| EPG46_RS24415 () | 119966..120340 | - | 375 | WP_176488922.1 | type II toxin-antitoxin system PemK/MazF family toxin | - |
| EPG46_RS24420 () | 120301..120558 | - | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| EPG46_RS24425 () | 120651..120985 | - | 335 | Protein_133 | CPBP family intramembrane metalloprotease | - |
| EPG46_RS24430 () | 121408..121548 | - | 141 | WP_001333237.1 | hypothetical protein | - |
| EPG46_RS24435 () | 122249..123077 | - | 829 | Protein_135 | incFII family plasmid replication initiator RepA | - |
| EPG46_RS24440 () | 123070..123144 | - | 75 | WP_001365705.1 | RepA leader peptide Tap | - |
| EPG46_RS24445 () | 123380..123637 | - | 258 | WP_000083833.1 | replication regulatory protein RepA | - |
| EPG46_RS24450 () | 123921..124127 | - | 207 | WP_032215358.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| - () | 124114..124175 | + | 62 | NuclAT_0 | - | Antitoxin Detail |
| - () | 124114..124175 | + | 62 | NuclAT_0 | - | Antitoxin Detail |
| - () | 124114..124175 | + | 62 | NuclAT_0 | - | Antitoxin Detail |
| - () | 124114..124175 | + | 62 | NuclAT_0 | - | Antitoxin Detail |
| EPG46_RS24455 () | 124314..124580 | - | 267 | WP_087757657.1 | hypothetical protein | - |
| EPG46_RS24460 () | 124955..125524 | - | 570 | WP_029702150.1 | DUF2726 domain-containing protein | - |
| EPG46_RS24465 () | 125676..126302 | - | 627 | WP_029702149.1 | hypothetical protein | - |
| EPG46_RS24470 () | 126714..126923 | - | 210 | WP_039023209.1 | hypothetical protein | - |
| EPG46_RS24475 () | 127054..127614 | - | 561 | WP_001567328.1 | fertility inhibition protein FinO | - |
| EPG46_RS24480 () | 127669..128415 | - | 747 | WP_052273601.1 | conjugal transfer pilus acetylase TraX | - |
| EPG46_RS24485 () | 128443..129193 | - | 751 | Protein_145 | IS21 family transposase ISEc12 | Transposase |
| EPG46_RS24490 () | 129208..130753 | - | 1546 | Protein_146 | IS21-like element ISEc12 family transposase | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|