MGE detailed information
MGE type: Conjugative plasmid MGE length: 88121 bp
Accession: NZ_AP022550 Location: 1..88121 Organism: Escherichia coli strain THO-015 Replicon: plasmid pTHO-015-1
Accession: NZ_AP022550 Location: 1..88121 Organism: Escherichia coli strain THO-015 Replicon: plasmid pTHO-015-1
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| JLF69_RS24435 () | 101..856 | + | 756 | WP_000852146.1 | replication initiation protein RepE | - |
| JLF69_RS24440 () | 1444..2610 | + | 1167 | WP_000772446.1 | plasmid-partitioning protein SopA | - |
| JLF69_RS24445 () | 2610..3581 | + | 972 | WP_000817036.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| JLF69_RS24450 () | 4448..5350 | + | 903 | WP_001348615.1 | DUF1281 domain-containing protein | - |
| JLF69_RS24455 () | 5354..5658 | + | 305 | Protein_4 | hypothetical protein | - |
| JLF69_RS24460 () | 5735..6418 | + | 684 | WP_000086185.1 | DNA methylase | - |
| JLF69_RS24465 () | 6419..6640 | + | 222 | WP_001104873.1 | hypothetical protein | - |
| JLF69_RS24470 () | 6654..7088 | + | 435 | WP_000274437.1 | DUF1380 family protein | - |
| JLF69_RS24475 () | 7139..7915 | + | 777 | WP_001753849.1 | hypothetical protein | - |
| JLF69_RS24480 () | 8455..8757 | + | 303 | WP_001671341.1 | antirestriction protein | - |
| JLF69_RS24485 () | 8804..9226 | + | 423 | WP_000271753.1 | DUF1380 family protein | - |
| JLF69_RS24490 () | 9223..9414 | + | 192 | WP_001027516.1 | hypothetical protein | - |
| JLF69_RS24495 () | 10449..10679 | + | 231 | WP_000218642.1 | hypothetical protein | - |
| JLF69_RS24500 () | 10731..12092 | + | 1362 | WP_000170714.1 | DUF3560 domain-containing protein | - |
| JLF69_RS24505 () | 12140..12703 | + | 564 | WP_001348621.1 | class I SAM-dependent methyltransferase | - |
| JLF69_RS24510 () | 12729..12971 | + | 243 | WP_001617878.1 | hypothetical protein | - |
| JLF69_RS24515 () | 13134..13469 | + | 336 | WP_013023883.1 | hypothetical protein | - |
| JLF69_RS24520 () | 13614..14153 | + | 540 | WP_000290841.1 | single-stranded DNA-binding protein | - |
| JLF69_RS24525 () | 14216..14449 | + | 234 | WP_000005990.1 | DUF905 family protein | - |
| JLF69_RS24530 () | 14515..16473 | + | 1959 | WP_000117179.1 | ParB/RepB/Spo0J family partition protein | - |
| JLF69_RS24535 () | 16528..16962 | + | 435 | WP_000845940.1 | conjugation system SOS inhibitor PsiB | - |
| JLF69_RS24540 () | 16959..17678 | + | 720 | WP_001276232.1 | plasmid SOS inhibition protein A | - |
| - () | 17690..17876 | + | 187 | NuclAT_0 | - | - |
| - () | 17690..17876 | + | 187 | NuclAT_0 | - | - |
| - () | 17690..17876 | + | 187 | NuclAT_0 | - | - |
| - () | 17690..17876 | + | 187 | NuclAT_0 | - | - |
| JLF69_RS24545 () | 17924..19293 | + | 1370 | WP_085947770.1 | IS3-like element IS150 family transposase | - |
| - () | 19320..19360 | + | 41 | NuclAT_1 | - | Antitoxin Detail |
| - () | 19320..19360 | + | 41 | NuclAT_1 | - | Antitoxin Detail |
| - () | 19320..19360 | + | 41 | NuclAT_1 | - | Antitoxin Detail |
| - () | 19320..19360 | + | 41 | NuclAT_1 | - | Antitoxin Detail |
| JLF69_RS24550 () | 19404..19562 | + | 159 | WP_001312861.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| JLF69_RS24555 () | 20005..20340 | + | 336 | WP_013023876.1 | hypothetical protein | - |
| JLF69_RS24560 () | 20253..20459 | + | 207 | WP_000275859.1 | hypothetical protein | - |
| JLF69_RS24565 () | 20484..20771 | + | 288 | WP_000107535.1 | hypothetical protein | - |
| JLF69_RS24570 () | 20890..21711 | + | 822 | WP_001234469.1 | DUF945 domain-containing protein | - |
| JLF69_RS24575 () | 22008..22610 | - | 603 | WP_000243712.1 | transglycosylase SLT domain-containing protein | - |
| JLF69_RS24580 () | 22941..23324 | + | 384 | WP_001151566.1 | relaxosome protein TraM | - |
| JLF69_RS24585 () | 23458..24135 | + | 678 | WP_001348626.1 | PAS domain-containing protein | - |
| JLF69_RS24590 () | 24223..24450 | + | 228 | WP_001254388.1 | conjugal transfer relaxosome protein TraY | - |
| JLF69_RS24595 () | 24484..24846 | + | 363 | WP_000338606.1 | type IV conjugative transfer system pilin TraA | - |
| JLF69_RS24600 () | 24851..25162 | + | 312 | WP_000012107.1 | type IV conjugative transfer system protein TraL | - |
| JLF69_RS24605 () | 25236..25933 | + | 698 | Protein_34 | IS1 family transposase | - |
| JLF69_RS24610 () | 25981..26301 | + | 321 | WP_001348757.1 | conjugal transfer protein TrbA | - |
| JLF69_RS24615 () | 26428..26712 | + | 285 | WP_001617873.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| JLF69_RS24620 () | 26699..27244 | + | 546 | WP_000059829.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| JLF69_RS24625 () | 27174..27521 | + | 348 | WP_071571857.1 | P-type conjugative transfer protein TrbJ | - |
| JLF69_RS24630 () | 27469..27894 | + | 426 | WP_001348758.1 | F-type conjugal transfer protein TrbF | - |
| JLF69_RS24635 () | 27881..29254 | + | 1374 | WP_000944328.1 | conjugal transfer protein TraH | - |
| JLF69_RS24640 () | 29251..32070 | + | 2820 | WP_001007062.1 | conjugal transfer mating pair stabilization protein TraG | - |
| JLF69_RS24645 () | 32089..32586 | + | 498 | WP_000605862.1 | entry exclusion protein | - |
| JLF69_RS24650 () | 32618..33349 | + | 732 | WP_000850429.1 | complement resistance protein TraT | - |
| JLF69_RS24655 () | 33552..34331 | + | 780 | WP_000199914.1 | hypothetical protein | - |
| JLF69_RS24660 () | 34328..36517 | + | 2190 | WP_024946705.1 | type IV conjugative transfer system coupling protein TraD | - |
| JLF69_RS24665 () | 36517..41787 | + | 5271 | WP_001617867.1 | conjugative transfer relaxase/helicase TraI | - |
| JLF69_RS24670 () | 41807..42553 | + | 747 | WP_000205718.1 | conjugal transfer pilus acetylase TraX | - |
| JLF69_RS24675 () | 42608..43168 | + | 561 | WP_000139341.1 | fertility inhibition protein FinO | - |
| JLF69_RS24680 () | 43299..43511 | + | 213 | WP_013023861.1 | hypothetical protein | - |
| JLF69_RS24685 () | 44070..44495 | + | 426 | WP_000422741.1 | IS66 family insertion sequence hypothetical protein | - |
| JLF69_RS24690 () | 44492..44842 | + | 351 | WP_000624722.1 | IS66 family insertion sequence element accessory protein TnpB | - |
| JLF69_RS24695 () | 44873..46486 | + | 1614 | WP_000080195.1 | IS66-like element ISEc23 family transposase | - |
| JLF69_RS24700 () | 46564..46850 | + | 287 | Protein_53 | DUF2726 domain-containing protein | - |
| - () | 46817..46877 | - | 61 | NuclAT_2 | - | Antitoxin Detail |
| - () | 46817..46877 | - | 61 | NuclAT_2 | - | Antitoxin Detail |
| - () | 46817..46877 | - | 61 | NuclAT_2 | - | Antitoxin Detail |
| - () | 46817..46877 | - | 61 | NuclAT_2 | - | Antitoxin Detail |
| JLF69_RS24705 () | 46922..47056 | + | 135 | WP_023144756.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| JLF69_RS24710 () | 47353..47607 | + | 255 | WP_000083850.1 | replication regulatory protein RepA | - |
| JLF69_RS24715 () | 47713..47847 | + | 135 | Protein_56 | protein CopA/IncA | - |
| JLF69_RS24720 () | 47844..47918 | + | 75 | WP_031943482.1 | RepA leader peptide Tap | - |
| JLF69_RS24725 () | 47911..48768 | + | 858 | WP_001617855.1 | incFII family plasmid replication initiator RepA | - |
| JLF69_RS24730 () | 49708..50361 | + | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| JLF69_RS24735 () | 50454..50711 | + | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| JLF69_RS24740 () | 50644..51045 | + | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| JLF69_RS24745 () | 51294..51709 | + | 416 | Protein_62 | IS1 family transposase | - |
| JLF69_RS24750 () | 51745..52290 | - | 546 | Protein_63 | Tn3 family transposase | - |
| JLF69_RS24755 () | 52356..53060 | - | 705 | WP_001067855.1 | IS6-like element IS26 family transposase | - |
| JLF69_RS24760 () | 53374..54249 | + | 876 | WP_032277257.1 | class A extended-spectrum beta-lactamase CTX-M-27 | - |
| JLF69_RS24765 () | 54284..54646 | + | 363 | Protein_66 | transposase | - |
| JLF69_RS24770 () | 54706..55410 | + | 705 | WP_001067858.1 | IS6-like element IS26 family transposase | - |
| JLF69_RS24775 () | 55463..55795 | + | 333 | Protein_68 | EamA family transporter | - |
| JLF69_RS24780 () | 55827..57026 | - | 1200 | WP_000804064.1 | tetracycline efflux MFS transporter Tet(A) | - |
| JLF69_RS24785 () | 57132..57758 | + | 627 | WP_031606906.1 | tetracycline resistance transcriptional repressor TetR(A) | - |
| JLF69_RS24790 () | 57790..58026 | - | 237 | WP_042005022.1 | hypothetical protein | - |
| JLF69_RS24795 () | 58080..58916 | - | 837 | WP_000480972.1 | aminoglycoside O-phosphotransferase APH(6)-Id | - |
| JLF69_RS24800 () | 58916..59719 | - | 804 | WP_001082319.1 | aminoglycoside O-phosphotransferase APH(3'')-Ib | - |
| JLF69_RS24805 () | 59780..60595 | - | 816 | WP_001043260.1 | sulfonamide-resistant dihydropteroate synthase Sul2 | - |
| JLF69_RS24810 () | 60903..61079 | - | 177 | Protein_75 | replication protein C | - |
| JLF69_RS24815 () | 61140..61844 | + | 705 | WP_001067855.1 | IS6-like element IS26 family transposase | - |
| JLF69_RS24820 () | 61966..62871 | + | 906 | WP_000219391.1 | Mph(A) family macrolide 2'-phosphotransferase | - |
| JLF69_RS24825 () | 62868..64106 | + | 1239 | WP_000004159.1 | MFS transporter | - |
| JLF69_RS24830 () | 64106..64690 | + | 585 | WP_001137892.1 | TetR family transcriptional regulator | - |
| JLF69_RS24835 () | 65183..65947 | - | 765 | WP_001389365.1 | IS6-like element IS6100 family transposase | - |
| JLF69_RS24840 () | 66065..66130 | - | 66 | Protein_81 | EAL domain-containing protein | - |
| JLF69_RS24845 () | 66174..66479 | - | 306 | WP_000130000.1 | PadR family transcriptional regulator | - |
| JLF69_RS24850 () | 66490..67695 | - | 1206 | WP_000184001.1 | chromate efflux transporter | - |
| JLF69_RS24855 () | 67851..68054 | - | 204 | WP_000376616.1 | hypothetical protein | - |
| JLF69_RS24860 () | 68182..69021 | - | 840 | WP_000259031.1 | sulfonamide-resistant dihydropteroate synthase Sul1 | - |
| JLF69_RS24865 () | 69015..69362 | - | 348 | WP_000679427.1 | quaternary ammonium compound efflux SMR transporter QacE delta 1 | - |
| JLF69_RS24870 () | 69568..70356 | - | 789 | WP_000503573.1 | ANT(3'')-Ia family aminoglycoside nucleotidyltransferase AadA5 | - |
| JLF69_RS24875 () | 70487..70960 | - | 474 | WP_001389366.1 | trimethoprim-resistant dihydrofolate reductase DfrA17 | - |
| JLF69_RS24880 () | 71242..71946 | - | 705 | WP_001067858.1 | IS6-like element IS26 family transposase | - |
| JLF69_RS24885 () | 72135..72548 | - | 414 | Protein_90 | DDE-type integrase/transposase/recombinase | - |
| JLF69_RS24890 () | 72472..72831 | - | 360 | WP_001513660.1 | hypothetical protein | - |
| JLF69_RS24895 () | 72859..73038 | - | 180 | WP_001513661.1 | hypothetical protein | - |
| JLF69_RS24900 () | 73043..73423 | - | 381 | WP_001216034.1 | type II toxin-antitoxin system death-on-curing family toxin | Toxin Detail |
| JLF69_RS24905 () | 73423..73644 | - | 222 | WP_001190712.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin Detail |
| JLF69_RS24910 () | 73827..75383 | + | 1557 | WP_001617892.1 | type I restriction-modification system subunit M | - |
| JLF69_RS24915 () | 75380..76651 | + | 1272 | WP_023142242.1 | restriction endonuclease subunit S | - |
| JLF69_RS24920 () | 76773..79889 | + | 3117 | WP_001553854.1 | HsdR family type I site-specific deoxyribonuclease | - |
| JLF69_RS24925 () | 80103..80512 | + | 410 | Protein_98 | IS1 family transposase | - |
| JLF69_RS24930 () | 80597..81022 | + | 426 | WP_000422741.1 | IS66 family insertion sequence hypothetical protein | - |
| JLF69_RS24935 () | 81019..81369 | + | 351 | WP_000624722.1 | IS66 family insertion sequence element accessory protein TnpB | - |
| JLF69_RS24940 () | 81400..83013 | + | 1614 | WP_000080195.1 | IS66-like element ISEc23 family transposase | - |
| JLF69_RS24945 () | 83044..83340 | + | 297 | Protein_102 | IS1-like element IS1A family transposase | - |
| JLF69_RS24950 () | 83477..84409 | - | 933 | WP_000991832.1 | hypothetical protein | - |
| JLF69_RS24955 () | 84413..85408 | - | 996 | WP_000246636.1 | hypothetical protein | - |
| JLF69_RS24960 () | 86116..86334 | + | 219 | WP_000813634.1 | type II toxin-antitoxin system antitoxin CcdA | - |
| JLF69_RS24965 () | 86336..86641 | + | 306 | WP_001159868.1 | type II toxin-antitoxin system toxin CcdB | - |
| JLF69_RS24970 () | 86642..87448 | + | 807 | WP_000016982.1 | site-specific integrase | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|