MGE detailed information
MGE type: Conjugative plasmid MGE length: 158292 bp
Accession: NZ_AP022096 Location: 1..158292 Organism: Escherichia coli strain WP4-S18-ESBL-08 Replicon: plasmid pWP4-S18-ESBL-08_1
Accession: NZ_AP022096 Location: 1..158292 Organism: Escherichia coli strain WP4-S18-ESBL-08 Replicon: plasmid pWP4-S18-ESBL-08_1
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| H7R08_RS23655 () | 101..1054 | + | 954 | WP_000280980.1 | hypothetical protein | VF |
| H7R08_RS23660 () | 1487..2596 | + | 1110 | WP_000771475.1 | SDR family oxidoreductase | - |
| H7R08_RS23665 () | 2665..3568 | + | 904 | Protein_2 | antimicrobial resistance protein Mig-14 | - |
| H7R08_RS23670 () | 3942..4130 | + | 189 | WP_001324033.1 | hypothetical protein | - |
| H7R08_RS23675 () | 4251..4991 | + | 741 | WP_001066954.1 | tyrosine-type recombinase/integrase | - |
| H7R08_RS23680 () | 5276..6253 | - | 978 | WP_000361611.1 | RepB family plasmid replication initiator protein | - |
| H7R08_RS23685 () | 6999..7322 | + | 324 | Protein_6 | IS21 family transposase IS21 | Transposase |
| H7R08_RS23690 () | 7324..7428 | + | 105 | Protein_7 | AAA family ATPase | - |
| H7R08_RS23695 () | 7489..8002 | + | 514 | Protein_8 | DUF4113 domain-containing protein | - |
| H7R08_RS23700 () | 8182..8879 | - | 698 | Protein_9 | IS1 family transposase IS1S | Transposase |
| H7R08_RS23705 () | 9235..10149 | + | 915 | WP_182913417.1 | hypothetical protein | VF |
| H7R08_RS23710 () | 10149..10976 | + | 828 | WP_000983710.1 | Vitamin B12 import ATP-binding protein BtuD | VF |
| H7R08_RS23715 () | 10973..11830 | + | 858 | WP_001101723.1 | hypothetical protein | ARG |
| H7R08_RS23720 () | 11827..12684 | + | 858 | WP_000968139.1 | hypothetical protein | ARG |
| H7R08_RS23725 () | 13173..13586 | + | 414 | Protein_14 | phosphopyruvate hydratase | - |
| H7R08_RS23730 () | 13927..14307 | + | 381 | WP_001318207.1 | fluoride efflux transporter CrcB | - |
| H7R08_RS23735 () | 14687..15880 | - | 1194 | WP_000095526.1 | MFS transporter | - |
| H7R08_RS23740 () | 16016..17740 | + | 1725 | WP_000602863.1 | hypothetical protein | VF |
| H7R08_RS23745 () | 17741..18688 | + | 948 | WP_000011908.1 | hypothetical protein | VF |
| H7R08_RS23750 () | 18688..20430 | + | 1743 | WP_001015721.1 | hypothetical protein | VF |
| H7R08_RS23755 () | 20427..21704 | + | 1278 | WP_000750130.1 | Ferredoxin--NADP reductase | VF |
| H7R08_RS23760 () | 21786..23987 | + | 2202 | WP_000973519.1 | Vitamin B12 transporter BtuB | VF |
| H7R08_RS23765 () | 24367..25064 | + | 698 | Protein_22 | IS1 family transposase IS1S | Transposase |
| H7R08_RS23770 () | 25318..26340 | - | 1023 | WP_000361402.1 | helicase UvrD | - |
| H7R08_RS23775 () | 26325..27890 | - | 1566 | WP_001128474.1 | AAA family ATPase | - |
| H7R08_RS23780 () | 27965..28381 | - | 417 | WP_001034044.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| H7R08_RS23785 () | 28378..28608 | - | 231 | WP_001261286.1 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | Antitoxin Detail |
| H7R08_RS23790 () | 28989..32783 | + | 3795 | WP_001144731.1 | hypothetical protein | - |
| H7R08_RS23795 () | 32828..33244 | - | 417 | WP_001034046.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| H7R08_RS23800 () | 33241..33471 | - | 231 | WP_001261278.1 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | Antitoxin Detail |
| H7R08_RS23805 () | 33736..34236 | + | 501 | WP_000528932.1 | hypothetical protein | - |
| H7R08_RS23810 () | 34249..35022 | + | 774 | WP_000905949.1 | hypothetical protein | - |
| H7R08_RS23815 () | 35189..36322 | + | 1134 | WP_000545984.1 | DUF3800 domain-containing protein | - |
| H7R08_RS23820 () | 36356..36868 | - | 513 | WP_000151784.1 | hypothetical protein | - |
| H7R08_RS23825 () | 37436..37654 | + | 219 | WP_000813634.1 | type II toxin-antitoxin system antitoxin CcdA | Antitoxin Detail |
| H7R08_RS23830 () | 37656..37961 | + | 306 | WP_001159868.1 | type II toxin-antitoxin system toxin CcdB | Toxin Detail |
| H7R08_RS23835 () | 37962..38768 | + | 807 | WP_000016982.1 | site-specific integrase | - |
| H7R08_RS23840 () | 39520..40275 | + | 756 | WP_000852146.1 | replication initiation protein RepE | - |
| H7R08_RS23845 () | 40863..42029 | + | 1167 | WP_000772446.1 | hypothetical protein | VF |
| H7R08_RS23850 () | 42029..43000 | + | 972 | WP_000817035.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| H7R08_RS23855 () | 43910..44811 | + | 902 | Protein_40 | DUF1281 domain-containing protein | - |
| H7R08_RS23860 () | 44815..45120 | + | 306 | WP_010891292.1 | hypothetical protein | - |
| H7R08_RS23865 () | 45197..45880 | + | 684 | WP_000085939.1 | DNA methylase | - |
| H7R08_RS23870 () | 45881..46102 | + | 222 | WP_001104870.1 | hypothetical protein | - |
| H7R08_RS23875 () | 45996..46550 | + | 555 | WP_077248347.1 | DUF1380 family protein | - |
| H7R08_RS23880 () | 46596..47372 | + | 777 | WP_001005035.1 | hypothetical protein | - |
| H7R08_RS23885 () | 47908..48210 | + | 303 | WP_072148062.1 | antirestriction protein | - |
| H7R08_RS23890 () | 48257..48679 | + | 423 | WP_000271685.1 | DUF1380 family protein | - |
| H7R08_RS23895 () | 48676..48867 | + | 192 | WP_001027495.1 | hypothetical protein | - |
| H7R08_RS23900 () | 48837..49346 | - | 510 | WP_071600123.1 | hypothetical protein | - |
| H7R08_RS23905 () | 49664..50203 | + | 540 | WP_000290801.1 | single-stranded DNA-binding protein | - |
| H7R08_RS23910 () | 50260..50493 | + | 234 | WP_000005990.1 | DUF905 family protein | - |
| H7R08_RS23915 () | 50559..52517 | + | 1959 | WP_029487628.1 | ParB/RepB/Spo0J family partition protein | - |
| H7R08_RS23920 () | 52572..53006 | + | 435 | WP_000845928.1 | conjugation system SOS inhibitor PsiB | - |
| H7R08_RS23925 () | 53003..53722 | + | 720 | WP_000116348.1 | plasmid SOS inhibition protein A | - |
| - () | 53734..53932 | + | 199 | NuclAT_0 | - | - |
| - () | 53734..53932 | + | 199 | NuclAT_0 | - | - |
| - () | 53734..53932 | + | 199 | NuclAT_0 | - | - |
| - () | 53734..53932 | + | 199 | NuclAT_0 | - | - |
| H7R08_RS23930 () | 53997..54155 | + | 159 | WP_001302184.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| H7R08_RS23935 () | 54393..54752 | - | 360 | Protein_56 | hypothetical protein | - |
| H7R08_RS23940 () | 54822..55028 | + | 207 | WP_000547965.1 | hypothetical protein | - |
| H7R08_RS23945 () | 55053..55340 | + | 288 | WP_000107546.1 | hypothetical protein | - |
| H7R08_RS23950 () | 55459..56280 | + | 822 | WP_001234475.1 | DUF945 domain-containing protein | - |
| H7R08_RS23955 () | 56575..57165 | - | 591 | WP_166494936.1 | hypothetical protein | VF |
| H7R08_RS23960 () | 57517..57900 | + | 384 | WP_001063020.1 | relaxosome protein TraM | - |
| H7R08_RS23965 () | 58092..58739 | + | 648 | WP_000332520.1 | conjugal transfer transcriptional regulator TraJ | - |
| H7R08_RS23970 () | 58875..59090 | + | 216 | WP_001352842.1 | conjugal transfer relaxosome protein TraY | - |
| H7R08_RS23975 () | 59133..59498 | + | 366 | WP_000340282.1 | type IV conjugative transfer system pilin TraA | - |
| H7R08_RS23980 () | 59513..59824 | + | 312 | WP_000012106.1 | type IV conjugative transfer system protein TraL | - |
| H7R08_RS23985 () | 59846..60412 | + | 567 | WP_000399790.1 | type IV conjugative transfer system protein TraE | - |
| H7R08_RS23990 () | 60423..61127 | + | 705 | WP_148713163.1 | type-F conjugative transfer system secretin TraK | - |
| H7R08_RS23995 () | 61127..62554 | + | 1428 | WP_000146676.1 | conjugal transfer protein TraB | - |
| H7R08_RS24000 () | 62544..63134 | + | 591 | WP_000002787.1 | conjugal transfer protein TraP | - |
| H7R08_RS24005 () | 63088..63318 | + | 231 | WP_001442573.1 | conjugal transfer protein TrbD | - |
| H7R08_RS24010 () | 63330..63581 | + | 252 | WP_001038342.1 | conjugal transfer protein TrbG | - |
| H7R08_RS24015 () | 63578..64093 | + | 516 | WP_000809838.1 | type IV conjugative transfer system lipoprotein TraV | - |
| H7R08_RS24020 () | 64228..64449 | + | 222 | WP_001278689.1 | conjugal transfer protein TraR | - |
| H7R08_RS24025 () | 64609..67236 | + | 2628 | WP_001064245.1 | type IV secretion system protein TraC | - |
| H7R08_RS24030 () | 67233..67619 | + | 387 | WP_000099691.1 | type-F conjugative transfer system protein TrbI | - |
| H7R08_RS24035 () | 67616..68248 | + | 633 | WP_001203717.1 | type-F conjugative transfer system protein TraW | - |
| H7R08_RS24040 () | 68245..69237 | + | 993 | WP_000830183.1 | conjugal transfer pilus assembly protein TraU | - |
| H7R08_RS24045 () | 69246..69884 | + | 639 | WP_000777695.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| H7R08_RS24050 () | 69881..71689 | + | 1809 | WP_000821838.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| H7R08_RS24055 () | 71716..71973 | + | 258 | WP_000864318.1 | conjugal transfer protein TrbE | - |
| H7R08_RS24060 () | 71966..72709 | + | 744 | WP_001030377.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| H7R08_RS24065 () | 72725..73072 | + | 348 | WP_001287910.1 | conjugal transfer protein TrbA | - |
| H7R08_RS24070 () | 73074..73388 | - | 315 | WP_001324103.1 | hypothetical protein | - |
| H7R08_RS24075 () | 73469..73753 | + | 285 | WP_000624109.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| H7R08_RS24080 () | 73740..74285 | + | 546 | WP_000059851.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| H7R08_RS24085 () | 74215..74556 | + | 342 | WP_001443031.1 | P-type conjugative transfer protein TrbJ | - |
| H7R08_RS24090 () | 74510..74923 | + | 414 | WP_001324104.1 | F-type conjugal transfer protein TrbF | - |
| H7R08_RS24095 () | 74923..76296 | + | 1374 | WP_001517790.1 | conjugal transfer protein TraH | - |
| H7R08_RS24100 () | 76293..79115 | + | 2823 | WP_001007018.1 | conjugal transfer mating pair stabilization protein TraG | - |
| H7R08_RS24105 () | 79131..79628 | + | 498 | WP_000605857.1 | entry exclusion protein | - |
| H7R08_RS24110 () | 79660..80391 | + | 732 | WP_023565183.1 | complement resistance protein TraT | - |
| H7R08_RS24115 () | 80644..82797 | + | 2154 | WP_000009324.1 | type IV conjugative transfer system coupling protein TraD | - |
| H7R08_RS24120 () | 82806..83204 | - | 399 | WP_000911313.1 | tRNA(fMet)-specific endonuclease VapC | Toxin Detail |
| H7R08_RS24125 () | 83204..83431 | - | 228 | WP_000450520.1 | toxin-antitoxin system antitoxin VapB | Antitoxin Detail |
| H7R08_RS24130 () | 83513..88783 | + | 5271 | WP_000986963.1 | ATP-dependent RecD-like DNA helicase | Relaxase |
| H7R08_RS24135 () | 88803..89549 | + | 747 | WP_000205749.1 | conjugal transfer pilus acetylase TraX | - |
| H7R08_RS24140 () | 89608..90468 | + | 861 | WP_000704513.1 | hypothetical protein | VF |
| H7R08_RS24145 () | 90571..91131 | + | 561 | WP_000139315.1 | fertility inhibition protein FinO | - |
| H7R08_RS24150 () | 91267..91479 | + | 213 | WP_001299730.1 | ANR family transcriptional regulator | - |
| H7R08_RS24155 () | 91725..91799 | + | 75 | Protein_100 | endonuclease | - |
| - () | 92055..92116 | - | 62 | NuclAT_1 | - | - |
| - () | 92055..92116 | - | 62 | NuclAT_1 | - | - |
| - () | 92055..92116 | - | 62 | NuclAT_1 | - | - |
| - () | 92055..92116 | - | 62 | NuclAT_1 | - | - |
| H7R08_RS24160 () | 92103..92309 | + | 207 | WP_001351576.1 | type I toxin-antitoxin system Hok family toxin | - |
| H7R08_RS24165 () | 92593..92850 | + | 258 | WP_000083845.1 | replication regulatory protein RepA | - |
| H7R08_RS24170 () | 93082..93156 | + | 75 | WP_001442103.1 | RepA leader peptide Tap | - |
| H7R08_RS24175 () | 93149..93631 | + | 483 | WP_001273588.1 | hypothetical protein | - |
| H7R08_RS24180 () | 93624..94089 | + | 466 | Protein_105 | incFII family plasmid replication initiator RepA | - |
| H7R08_RS24185 () | 94022..97027 | - | 3006 | WP_001143760.1 | Tn3 family transposase TnpA_Tn3 | Transposase |
| H7R08_RS24190 () | 97191..97748 | + | 558 | WP_001235713.1 | Tn3 family transposase TnpR_Tn3 | Transposase |
| H7R08_RS24195 () | 97931..98791 | + | 861 | WP_000027057.1 | hypothetical protein | ARG |
| H7R08_RS24200 () | 99068..100645 | - | 1578 | WP_001323889.1 | Chromosome partition protein Smc | VF |
| H7R08_RS24205 () | 100955..101515 | + | 561 | WP_001161490.1 | Tn3 family transposase TnpR_TnAs1 | Transposase |
| H7R08_RS24210 () | 101519..104485 | + | 2967 | WP_001138014.1 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| H7R08_RS24215 () | 105343..105687 | + | 345 | WP_001553768.1 | hypothetical protein | - |
| H7R08_RS24220 () | 105868..106983 | - | 1116 | Protein_113 | IS91 family transposase IS91 | Transposase |
| H7R08_RS24225 () | 106983..107348 | - | 366 | WP_000124098.1 | hypothetical protein | - |
| H7R08_RS24230 () | 107470..108621 | - | 1152 | WP_001442799.1 | IS30 family transposase IS30D | Transposase |
| H7R08_RS24235 () | 108689..108946 | - | 258 | Protein_116 | IS3 family transposase IS911 | Transposase |
| H7R08_RS24240 () | 109042..109396 | + | 355 | Protein_117 | helix-turn-helix transcriptional regulator | - |
| H7R08_RS24245 () | 109587..113720 | + | 4134 | WP_001080137.1 | Temperature-sensitive hemagglutinin tsh autotransporter | VF |
| H7R08_RS24250 () | 113829..114281 | + | 453 | WP_001553770.1 | peptide deformylase | - |
| H7R08_RS24255 () | 114268..114534 | - | 267 | Protein_120 | Tn3 family transposase TnpR_TnEc1 | Transposase |
| H7R08_RS24260 () | 114574..116111 | - | 1538 | Protein_121 | IS66 family transposase ISEc8 | Transposase |
| H7R08_RS24265 () | 116161..116508 | - | 348 | WP_000612591.1 | IS66 family transposase ISEc8 | Transposase |
| H7R08_RS24270 () | 116505..116885 | - | 381 | WP_001171523.1 | IS66 family transposase ISEc8 | Transposase |
| H7R08_RS24275 () | 116961..117941 | - | 981 | WP_001017346.1 | NAD(P)-binding domain-containing protein | - |
| H7R08_RS24280 () | 117938..118207 | - | 270 | WP_000379710.1 | SemiSWEET transporter | - |
| H7R08_RS24285 () | 118209..118986 | - | 778 | Protein_126 | Gfo/Idh/MocA family oxidoreductase | - |
| H7R08_RS24290 () | 119147..119383 | + | 237 | WP_001323890.1 | colicin V immunity protein | - |
| H7R08_RS24295 () | 119361..119672 | + | 312 | WP_001259758.1 | colicin V | - |
| H7R08_RS24300 () | 119842..121956 | - | 2115 | WP_001183604.1 | peptidase domain-containing ABC transporter | - |
| H7R08_RS24305 () | 121931..123205 | - | 1275 | WP_000489609.1 | HlyD family secretion protein | - |
| H7R08_RS24310 () | 123887..124084 | + | 198 | WP_001324224.1 | toxin-antitoxin system protein | Antitoxin Detail |
| H7R08_RS24315 () | 124081..124263 | + | 183 | WP_000969988.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin Detail |
| H7R08_RS24320 () | 124362..124670 | + | 309 | WP_000377483.1 | hypothetical protein | - |
| H7R08_RS24325 () | 125230..126264 | + | 1035 | WP_001190234.1 | 3-deoxy-7-phosphoheptulonate synthase | - |
| H7R08_RS24330 () | 127130..129307 | + | 2178 | WP_001222185.1 | Vitamin B12 transporter BtuB | VF |
| H7R08_RS24335 () | 129352..130308 | - | 957 | WP_000271274.1 | hypothetical protein | VF |
| H7R08_RS24340 () | 130393..131622 | - | 1230 | WP_000933678.1 | hypothetical protein | VF |
| H7R08_RS24345 () | 131726..135385 | - | 3660 | WP_001389363.1 | Vitamin B12 import ATP-binding protein BtuD | VF |
| H7R08_RS24350 () | 135525..136640 | - | 1116 | WP_001318220.1 | hypothetical protein | VF |
| H7R08_RS24355 () | 137876..138975 | - | 1100 | Protein_140 | IS481 family transposase ISKpn28 | Transposase |
| H7R08_RS24360 () | 139529..139728 | + | 200 | Protein_141 | lysis protein | - |
| H7R08_RS24365 () | 139786..140079 | - | 294 | WP_000738422.1 | increased serum survival lipoprotein Iss | - |
| H7R08_RS24370 () | 140659..141224 | + | 566 | Protein_143 | IS3 family transposase IS2 | Transposase |
| H7R08_RS24380 () | 142465..143193 | + | 729 | Protein_145 | IS3 family transposase IS2 | Transposase |
| H7R08_RS24385 () | 144435..145628 | + | 1194 | WP_000450494.1 | GTP-binding protein | - |
| H7R08_RS24390 () | 145806..145955 | + | 150 | Protein_147 | IS3 family transposase IS2 | Transposase |
| H7R08_RS24395 () | 146265..147654 | + | 1390 | Protein_148 | ISNCY family transposase ISKpn21 | Transposase |
| H7R08_RS24400 () | 147889..148830 | + | 942 | WP_000974762.1 | hypothetical protein | - |
| H7R08_RS24405 () | 148959..149153 | - | 195 | Protein_150 | IS200/IS605-like element IS200C family transposase | - |
| H7R08_RS24410 () | 149627..150997 | - | 1371 | WP_001312828.1 | efflux transporter outer membrane subunit | - |
| H7R08_RS24415 () | 151001..152941 | - | 1941 | WP_000733250.1 | Vitamin B12 import ATP-binding protein BtuD | VF |
| H7R08_RS24420 () | 152938..154125 | - | 1188 | WP_000928804.1 | efflux RND transporter periplasmic adaptor subunit | - |
| H7R08_RS24425 () | 155106..155431 | + | 326 | Protein_154 | IS3 family transposase IS911 | Transposase |
| H7R08_RS24430 () | 155579..156778 | - | 1200 | Protein_155 | IS3 family transposase IS629 | Transposase |
| H7R08_RS24435 () | 156962..157120 | + | 159 | WP_001324039.1 | integrase core domain-containing protein | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|