MGE detailed information
MGE type: Conjugative plasmid MGE length: 131334 bp
Accession: NZ_AP022004 Location: 1..131334 Organism: Escherichia coli strain WP3-W18-ESBL-08 Replicon: plasmid pWP3-W18-ESBL-08_1
Accession: NZ_AP022004 Location: 1..131334 Organism: Escherichia coli strain WP3-W18-ESBL-08 Replicon: plasmid pWP3-W18-ESBL-08_1
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| H7R22_RS25135 () | 101..319 | - | 219 | WP_001336934.1 | hypothetical protein | - |
| H7R22_RS25140 () | 448..795 | + | 348 | WP_000142452.1 | hypothetical protein | - |
| H7R22_RS25145 () | 815..1324 | - | 510 | WP_000194542.1 | hypothetical protein | - |
| H7R22_RS25150 () | 1321..1581 | - | 261 | WP_000371883.1 | hypothetical protein | - |
| H7R22_RS25155 () | 1683..2422 | + | 740 | Protein_4 | IS3 family transposase IS629 | Transposase |
| H7R22_RS25160 () | 3095..4603 | + | 1509 | WP_032145081.1 | group II intron reverse transcriptase/maturase | - |
| H7R22_RS25165 () | 4687..5166 | + | 480 | Protein_6 | IS3 family transposase IS629 | Transposase |
| H7R22_RS25170 () | 5256..5692 | + | 437 | Protein_7 | IS3 family transposase IS2 | Transposase |
| H7R22_RS25175 () | 6217..6489 | + | 273 | WP_001322642.1 | adhesin biosynthesis transcription regulatory family protein | - |
| H7R22_RS25180 () | 6935..7110 | + | 176 | Protein_9 | IS3 family transposase | - |
| H7R22_RS25185 () | 7336..8505 | - | 1170 | WP_001072358.1 | hypothetical protein | - |
| H7R22_RS25190 () | 8872..9060 | + | 189 | WP_001332784.1 | hypothetical protein | - |
| H7R22_RS25195 () | 9181..9921 | + | 741 | WP_001066947.1 | IS91 family transposase ISMno23 | Transposase |
| H7R22_RS25200 () | 10164..11141 | - | 978 | WP_001309253.1 | RepB family plasmid replication initiator protein | - |
| H7R22_RS25205 () | 11785..12196 | - | 412 | Protein_14 | DDE-type integrase/transposase/recombinase | - |
| H7R22_RS25210 () | 12198..12485 | - | 288 | WP_001270422.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin Detail |
| H7R22_RS25215 () | 12482..12733 | - | 252 | WP_001132895.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin Detail |
| H7R22_RS25220 () | 13491..14696 | + | 1206 | WP_000817635.1 | Plasmid partition protein A | VF |
| H7R22_RS25225 () | 14693..15655 | + | 963 | WP_000756328.1 | ParB/RepB/Spo0J family partition protein | - |
| H7R22_RS25230 () | 15889..16665 | + | 777 | Protein_19 | hypothetical protein | - |
| H7R22_RS25235 () | 16832..16975 | + | 144 | WP_000270807.1 | DUF1281 domain-containing protein | - |
| H7R22_RS25240 () | 16982..17341 | + | 360 | WP_001336695.1 | DUF1281 domain-containing protein | - |
| H7R22_RS25245 () | 17405..17716 | + | 312 | WP_001309256.1 | hypothetical protein | - |
| H7R22_RS25250 () | 17792..18475 | + | 684 | WP_000086171.1 | DNA methylase | - |
| H7R22_RS25255 () | 18476..18697 | + | 222 | WP_001104892.1 | hypothetical protein | - |
| H7R22_RS25260 () | 18711..19145 | + | 435 | WP_000274451.1 | DUF1380 family protein | - |
| H7R22_RS25265 () | 19190..19960 | + | 771 | WP_001044390.1 | hypothetical protein | - |
| H7R22_RS25270 () | 20497..20799 | + | 303 | WP_001364029.1 | antirestriction protein | - |
| H7R22_RS25275 () | 20799..21260 | + | 462 | WP_046881848.1 | DUF1380 family protein | - |
| H7R22_RS25280 () | 21260..21451 | + | 192 | WP_001027049.1 | hypothetical protein | - |
| H7R22_RS25285 () | 21430..21738 | - | 309 | WP_050576143.1 | hypothetical protein | - |
| H7R22_RS25290 () | 22419..22649 | + | 231 | WP_001537563.1 | hypothetical protein | - |
| H7R22_RS25295 () | 22701..24062 | + | 1362 | WP_000170705.1 | DUF3560 domain-containing protein | - |
| H7R22_RS25300 () | 24109..24672 | + | 564 | WP_001309257.1 | class I SAM-dependent methyltransferase | - |
| H7R22_RS25305 () | 25485..26012 | + | 528 | WP_000290834.1 | single-stranded DNA-binding protein | - |
| H7R22_RS25310 () | 26070..26303 | + | 234 | WP_000006003.1 | DUF905 family protein | - |
| H7R22_RS25315 () | 26364..28328 | + | 1965 | WP_001537566.1 | ParB/RepB/Spo0J family partition protein | - |
| H7R22_RS25320 () | 28397..28831 | + | 435 | WP_000845953.1 | conjugation system SOS inhibitor PsiB | - |
| H7R22_RS25325 () | 28828..29547 | + | 720 | WP_001276217.1 | plasmid SOS inhibition protein A | - |
| - () | 29559..29783 | + | 225 | NuclAT_0 | - | - |
| - () | 29559..29783 | + | 225 | NuclAT_0 | - | - |
| - () | 29559..29783 | + | 225 | NuclAT_0 | - | - |
| - () | 29559..29783 | + | 225 | NuclAT_0 | - | - |
| H7R22_RS25330 () | 29568..29747 | - | 180 | WP_001309233.1 | hypothetical protein | - |
| H7R22_RS25335 () | 29827..29985 | + | 159 | WP_001312861.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| H7R22_RS25340 () | 30286..30490 | - | 205 | Protein_41 | pilus protein | - |
| H7R22_RS25345 () | 30882..31178 | + | 297 | WP_001545326.1 | hypothetical protein | - |
| H7R22_RS25350 () | 31288..32109 | + | 822 | WP_001234445.1 | DUF945 domain-containing protein | - |
| H7R22_RS25355 () | 32406..33008 | - | 603 | Protein_44 | hypothetical protein | VF |
| H7R22_RS25360 () | 33329..33712 | + | 384 | WP_001151538.1 | relaxosome protein TraM | - |
| H7R22_RS25365 () | 33899..34588 | + | 690 | WP_000283387.1 | conjugal transfer transcriptional regulator TraJ | - |
| H7R22_RS25370 () | 34687..35082 | + | 396 | WP_001309237.1 | conjugal transfer relaxosome protein TraY | - |
| H7R22_RS25375 () | 35115..35474 | + | 360 | WP_113366028.1 | type IV conjugative transfer system pilin TraA | - |
| H7R22_RS25380 () | 35489..35800 | + | 312 | WP_000012100.1 | type IV conjugative transfer system protein TraL | - |
| H7R22_RS25385 () | 35822..36388 | + | 567 | WP_000399780.1 | type IV conjugative transfer system protein TraE | - |
| H7R22_RS25390 () | 36375..37103 | + | 729 | WP_001230767.1 | type-F conjugative transfer system secretin TraK | - |
| H7R22_RS25395 () | 37103..38554 | + | 1452 | WP_000146663.1 | conjugal transfer protein TraB | - |
| H7R22_RS25400 () | 38523..39110 | + | 588 | WP_001309238.1 | conjugal transfer protein TraP | - |
| H7R22_RS25405 () | 39064..39414 | + | 351 | WP_071586941.1 | conjugal transfer protein TrbD | - |
| H7R22_RS25410 () | 39414..39929 | + | 516 | WP_000809872.1 | type IV conjugative transfer system lipoprotein TraV | - |
| H7R22_RS25415 () | 40064..40285 | + | 222 | WP_001278695.1 | conjugal transfer protein TraR | - |
| H7R22_RS25420 () | 40278..40691 | + | 414 | WP_000549574.1 | hypothetical protein | - |
| H7R22_RS25425 () | 40684..41157 | + | 474 | WP_000549566.1 | hypothetical protein | - |
| H7R22_RS25430 () | 41822..44452 | + | 2631 | WP_000069771.1 | type IV secretion system protein TraC | - |
| H7R22_RS25435 () | 44449..44835 | + | 387 | WP_000214084.1 | type-F conjugative transfer system protein TrbI | - |
| H7R22_RS25440 () | 44832..45464 | + | 633 | WP_001203720.1 | type-F conjugative transfer system protein TraW | - |
| H7R22_RS25445 () | 45461..46453 | + | 993 | WP_000830838.1 | conjugal transfer pilus assembly protein TraU | - |
| H7R22_RS25450 () | 46480..46788 | + | 309 | WP_000412445.1 | hypothetical protein | - |
| H7R22_RS25455 () | 46851..47369 | + | 519 | WP_000009088.1 | hypothetical protein | - |
| H7R22_RS25460 () | 47396..48034 | + | 639 | WP_000087539.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| H7R22_RS25465 () | 48031..48402 | + | 372 | WP_000174465.1 | hypothetical protein | - |
| H7R22_RS25470 () | 48427..48849 | + | 423 | WP_001229309.1 | HNH endonuclease | - |
| H7R22_RS25475 () | 48846..50696 | + | 1851 | WP_113366027.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| H7R22_RS25480 () | 50723..50980 | + | 258 | WP_000864310.1 | conjugal transfer protein TrbE | - |
| H7R22_RS25485 () | 50973..51716 | + | 744 | WP_001030371.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| H7R22_RS25490 () | 51730..52071 | + | 342 | WP_000556795.1 | conjugal transfer protein TrbA | - |
| H7R22_RS25495 () | 52127..52387 | - | 261 | WP_000736412.1 | hypothetical protein | - |
| H7R22_RS25500 () | 52468..52752 | + | 285 | WP_000624194.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| H7R22_RS25505 () | 52739..53284 | + | 546 | WP_000059830.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| H7R22_RS25510 () | 53214..53588 | + | 375 | WP_071586940.1 | P-type conjugative transfer protein TrbJ | - |
| H7R22_RS25515 () | 53509..53934 | + | 426 | WP_001336804.1 | F-type conjugal transfer protein TrbF | - |
| H7R22_RS25520 () | 53921..55294 | + | 1374 | WP_000944331.1 | conjugal transfer protein TraH | - |
| H7R22_RS25525 () | 55291..58110 | + | 2820 | WP_001537571.1 | conjugal transfer mating pair stabilization protein TraG | - |
| H7R22_RS25530 () | 58129..58626 | + | 498 | WP_000605862.1 | entry exclusion protein | - |
| H7R22_RS25535 () | 58658..59389 | + | 732 | WP_000850422.1 | complement resistance protein TraT | - |
| H7R22_RS25540 () | 59592..60329 | + | 738 | WP_000199901.1 | hypothetical protein | - |
| H7R22_RS25545 () | 60380..62623 | + | 2244 | WP_033550317.1 | type IV conjugative transfer system coupling protein TraD | - |
| H7R22_RS25550 () | 62623..67893 | + | 5271 | WP_001545323.1 | Multifunctional conjugation protein TraI | Relaxase |
| H7R22_RS25555 () | 67913..68659 | + | 747 | WP_000205709.1 | conjugal transfer pilus acetylase TraX | - |
| H7R22_RS25560 () | 68714..69271 | + | 558 | WP_000139329.1 | fertility inhibition protein FinO | - |
| H7R22_RS25565 () | 70379..70840 | + | 462 | WP_000760080.1 | thermonuclease family protein | - |
| H7R22_RS25570 () | 70943..71326 | + | 384 | WP_001109264.1 | hypothetical protein | - |
| H7R22_RS25575 () | 71479..71916 | + | 438 | WP_000872609.1 | hypothetical protein | - |
| - () | 72011..72067 | - | 57 | NuclAT_1 | - | Antitoxin Detail |
| - () | 72011..72067 | - | 57 | NuclAT_1 | - | Antitoxin Detail |
| - () | 72011..72067 | - | 57 | NuclAT_1 | - | Antitoxin Detail |
| - () | 72011..72067 | - | 57 | NuclAT_1 | - | Antitoxin Detail |
| H7R22_RS25580 () | 72115..72264 | + | 150 | WP_001336447.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| H7R22_RS25585 () | 72549..72806 | + | 258 | WP_000084404.1 | replication regulatory protein RepA | - |
| H7R22_RS25590 () | 73040..73114 | + | 75 | WP_001365705.1 | RepA leader peptide Tap | - |
| H7R22_RS25595 () | 73107..73964 | + | 858 | WP_001537577.1 | incFII family plasmid replication initiator RepA | - |
| H7R22_RS25600 () | 74665..74877 | + | 213 | WP_001336932.1 | hypothetical protein | - |
| H7R22_RS25605 () | 74992..75300 | - | 309 | Protein_94 | IS91 family transposase ISSbo1 | Transposase |
| H7R22_RS25610 () | 75493..75591 | + | 99 | WP_137491101.1 | transposase | - |
| H7R22_RS25615 () | 75741..75989 | - | 249 | WP_000738203.1 | hypothetical protein | - |
| H7R22_RS25620 () | 76019..76789 | - | 771 | WP_000712166.1 | molybdopterin-dependent oxidoreductase | - |
| H7R22_RS25625 () | 76800..77399 | - | 600 | WP_001177183.1 | cytochrome b/b6 domain-containing protein | - |
| H7R22_RS25630 () | 77541..78263 | + | 723 | WP_001057737.1 | Transcriptional regulatory protein WalR | VF |
| H7R22_RS25635 () | 78260..79732 | + | 1473 | WP_000621194.1 | sensor histidine kinase | - |
| H7R22_RS25640 () | 80110..80277 | - | 168 | Protein_101 | IS110 family transposase | - |
| H7R22_RS25645 () | 80331..81035 | - | 705 | WP_059328522.1 | IS6 family transposase IS26 | Transposase |
| H7R22_RS25650 () | 81368..82183 | + | 816 | WP_012372823.1 | Na(+)-translocating NADH-quinone reductase subunit C | - |
| H7R22_RS25655 () | 82530..84416 | + | 1887 | WP_001332815.1 | FTR1 family iron permease | - |
| H7R22_RS25660 () | 84457..84984 | + | 528 | WP_000178050.1 | iron transporter | - |
| H7R22_RS25665 () | 85088..86467 | + | 1380 | WP_000119836.1 | DUF2318 domain-containing protein | - |
| H7R22_RS25670 () | 86470..87753 | + | 1284 | WP_000964653.1 | ABC transporter permease | - |
| H7R22_RS25675 () | 87743..88873 | + | 1131 | WP_000729218.1 | ABC transporter permease | - |
| H7R22_RS25680 () | 88878..89573 | + | 696 | WP_000117262.1 | Lipoprotein-releasing system ATP-binding protein LolD | VF |
| H7R22_RS25685 () | 89560..90045 | + | 486 | WP_001267176.1 | TlpA family protein disulfide reductase | - |
| H7R22_RS25690 () | 90070..90555 | + | 486 | WP_000874189.1 | hypothetical protein | - |
| H7R22_RS25695 () | 90677..91309 | + | 633 | Protein_112 | histidine-type phosphatase | - |
| H7R22_RS25700 () | 91459..92438 | - | 980 | Protein_113 | IS5 family transposase ISKpn26 | Transposase |
| H7R22_RS25705 () | 92540..93109 | + | 570 | WP_001336919.1 | Serine protease EspC | VF |
| H7R22_RS25710 () | 93112..93585 | - | 474 | Protein_115 | IS3 family transposase IS629 | Transposase |
| H7R22_RS25715 () | 93675..95183 | - | 1509 | WP_001189111.1 | group II intron reverse transcriptase/maturase | - |
| H7R22_RS25720 () | 95856..96595 | - | 740 | Protein_117 | IS3 family transposase IS629 | Transposase |
| H7R22_RS25725 () | 96650..96898 | - | 249 | Protein_118 | IS21 family transposase IS21 | Transposase |
| H7R22_RS25730 () | 97381..98133 | + | 753 | WP_000471454.1 | Chaperone protein caf1M | VF |
| H7R22_RS25735 () | 98196..100712 | + | 2517 | WP_162929852.1 | F1 capsule-anchoring protein | VF |
| H7R22_RS25740 () | 100728..101150 | + | 423 | WP_000243157.1 | Protein AfaD | VF |
| H7R22_RS25745 () | 101258..101743 | + | 486 | WP_001545321.1 | Dr family adhesin structural subunit | - |
| H7R22_RS25755 () | 103481..103897 | + | 417 | WP_000466682.1 | SdiA-regulated domain-containing protein | - |
| H7R22_RS25760 () | 104102..104893 | - | 792 | WP_000456855.1 | Virulence regulon transcriptional activator VirF | VF |
| H7R22_RS25765 () | 105218..105723 | + | 506 | Protein_126 | IS3 family transposase IS3H | Transposase |
| H7R22_RS25770 () | 105716..105829 | + | 114 | Protein_127 | transposase | - |
| H7R22_RS25775 () | 105979..106977 | + | 999 | WP_000756334.1 | ABC transporter substrate-binding protein | - |
| H7R22_RS25780 () | 106977..108014 | + | 1038 | WP_001545318.1 | Hemin transport system permease protein HmuU | VF |
| H7R22_RS25785 () | 108014..108775 | + | 762 | WP_000020504.1 | Fe(3+) dicitrate transport ATP-binding protein FecE | VF |
| H7R22_RS25790 () | 108832..110019 | + | 1188 | WP_025999368.1 | MFS transporter | - |
| H7R22_RS25795 () | 110097..110372 | - | 276 | WP_000877662.1 | bacteriocin immunity protein | - |
| H7R22_RS25800 () | 110730..111029 | - | 300 | WP_000119542.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| H7R22_RS25805 () | 111019..111282 | - | 264 | WP_001089474.1 | hypothetical protein | - |
| H7R22_RS25810 () | 111389..111649 | - | 261 | WP_001545316.1 | hypothetical protein | - |
| H7R22_RS25815 () | 111859..112341 | - | 483 | WP_001337004.1 | hypothetical protein | - |
| H7R22_RS25820 () | 112458..113306 | - | 849 | WP_001057995.1 | 3'-5' exonuclease | - |
| H7R22_RS25825 () | 113422..113571 | - | 150 | Protein_138 | IS3 family transposase | - |
| H7R22_RS25830 () | 113610..115148 | - | 1539 | WP_000099150.1 | IS66 family transposase ISEc22 | Transposase |
| H7R22_RS25835 () | 115197..115544 | - | 348 | WP_000612626.1 | IS66 family transposase ISKpn24 | Transposase |
| H7R22_RS25840 () | 115541..115945 | - | 405 | WP_000839179.1 | IS66 family transposase ISEc22 | Transposase |
| H7R22_RS25845 () | 116061..117095 | + | 1035 | Protein_142 | IS3 family transposase IS3 | Transposase |
| H7R22_RS25850 () | 117324..118832 | - | 1509 | WP_032145081.1 | group II intron reverse transcriptase/maturase | - |
| H7R22_RS25855 () | 119505..119855 | - | 351 | Protein_144 | IS3 family transposase IS629 | Transposase |
| H7R22_RS25860 () | 119941..121440 | + | 1500 | WP_000143800.1 | IS21 family transposase ISEc10 | Transposase |
| H7R22_RS25865 () | 121437..122192 | + | 756 | WP_000065240.1 | IS21 family transposase ISEc10 | Transposase |
| H7R22_RS25870 () | 122083..122660 | - | 578 | Protein_147 | IS3 family transposase IS629 | Transposase |
| H7R22_RS25875 () | 122686..122991 | + | 306 | Protein_148 | IS91 family transposase ISSbo1 | Transposase |
| H7R22_RS25880 () | 123514..124689 | - | 1176 | WP_001020413.1 | putative protein YncE | VF |
| H7R22_RS25885 () | 124758..127019 | - | 2262 | WP_001100763.1 | TonB-dependent receptor | - |
| H7R22_RS25890 () | 127188..127964 | - | 777 | WP_000981091.1 | energy transducer TonB | - |
| H7R22_RS25895 () | 127972..128847 | - | 876 | WP_001537591.1 | ChaN family lipoprotein | - |
| H7R22_RS25900 () | 129179..129865 | - | 687 | Protein_153 | replication initiation protein | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|