T4SS ID	584
Strain	Proteus mirabilis HI4320
Replicon	chromosome [Browse all T4SS(s) in this replicon]
Accession	NC_010554
Location	2653922..2661726; 2682565..2704628
Name	Tra_F
Function	conjugation
Classification	Type IVA; Type F
This T4SS has been mentioned in a genome sequencing report.

T4SS components

Component	TraA_F	TraB_F	TraC_F	TraD_F	TraE_F	TraF_F	TraG_F	TraH_F	TraI_F
Number	1	1	1	1	1	1	1	1	1
Component	TraK_F	TraL_F	TraM_F	TraN_F	TraQ_F	TraU_F	TraV_F	TraW_F	TraX_F
Number	1	1	0	1	0	1	1	1	0
Component	TraY_F	TrbC_F	Orf169_F
Number	0	0	1

The information of T4SS components from NC_010554
Region 1: 2653922..2661726
#	Locus tag (Gene)	Coordinates [+/-], size (bp)	Protein GI	Product	Component
1	PMI_RS11980 (prfC)	2649499..2651088 [-], 1590	490369782	peptide chain release factor 3
2	PMI_RS11985	2651345..2651992 [-], 648	446777664	LexA family transcriptional regulator
3	PMI_RS11990	2652110..2652361 [+], 252	446373891	helix-turn-helix domain-containing protein
4	PMI_RS11995	2652417..2653286 [+], 870	501336714	hypothetical protein
5	PMI_RS12000	2653327..2653935 [+], 609	487844829	hypothetical protein
6	PMI_RS12005	2653922..2654470 [+], 549	501336715	lytic transglycosylase domain-containing protein	Orf169_F
7	PMI_RS12010	2654467..2654766 [+], 300	446132708	flagellar transcriptional regulator FlhD
8	PMI_RS12015	2654763..2655296 [+], 534	446488899	hypothetical protein
9	PMI_RS12020	2655354..2655785 [+], 432	501336716	membrane protein
10	PMI_RS12025	2655818..2659387 [-], 3570	501336717	conjugal transfer protein TraG	TraG_F
11	PMI_RS12030	2659391..2660779 [-], 1389	501336718	conjugal transfer protein TraH	TraH_F
12	PMI_RS12035	2660782..2661726 [-], 945	501336719	thioredoxin family protein	TraF_F
13	PMI_RS12040	2662014..2663906 [-], 1893	501336720	ATP-dependent helicase
14	PMI_RS12045	2663903..2665867 [-], 1965	501336721	AAA family ATPase
15	PMI_RS19290	2666041..2666217 [-], 177	1774724758	hypothetical protein
Region 2: 2682565..2704628
#	Locus tag (Gene)	Coordinates [+/-], size (bp)	Protein GI	Product	Component
1	PMI_RS12115	2677804..2678406 [+], 603	501336735	hypothetical protein
2	PMI_RS12120	2678515..2679189 [+], 675	501336736	endonuclease
3	PMI_RS12125	2679254..2679772 [-], 519	501336737	hypothetical protein
4	PMI_RS12130	2679792..2682065 [-], 2274	501336738	dynamin family protein
5	PMI_RS12135	2682075..2682323 [-], 249	500112500	hypothetical protein
6	PMI_RS12140 (traN)	2682565..2686257 [-], 3693	501336739	conjugal transfer protein TraN	TraN_F
7	PMI_RS12145	2686260..2687288 [-], 1029	501336740	TraU family protein	TraU_F
8	PMI_RS12150	2687272..2688396 [-], 1125	754062049	pilus assembly protein
9	PMI_RS12155	2688407..2688919 [-], 513	501336742	S26 family signal peptidase
10	PMI_RS12160	2688903..2689250 [-], 348	501336743	hypothetical protein
11	PMI_RS12165 (traC)	2689243..2691642 [-], 2400	501336744	type IV secretion system protein TraC	TraC_F
12	PMI_RS12170	2691642..2692334 [-], 693	447151668	DsbC family protein
13	PMI_RS12175	2692466..2693404 [-], 939	501336745	nucleotidyl transferase AbiEii/AbiGii toxin family protein
14	PMI_RS12180	2693397..2694188 [-], 792	754062155	type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein
15	PMI_RS12185	2694408..2694794 [-], 387	446102370	hypothetical protein	TraA_F
16	PMI_RS12190 (traV)	2694791..2695363 [-], 573	487870625	type IV conjugative transfer system lipoprotein TraV
17	PMI_RS12195	2695438..2696727 [-], 1290	501336747	TraB/VirB10 family protein	TraB_F
18	PMI_RS12200	2696730..2697626 [-], 897	754062157	type-F conjugative transfer system secretin TraK
19	PMI_RS12205	2697610..2698236 [-], 627	446589824	hypothetical protein	TraE_F
20	PMI_RS12210 (traL)	2698233..2698514 [-], 282	446356036	type IV conjugative transfer system protein TraL	TraL_F
21	PMI_RS12220	2698803..2699390 [+], 588	501336750	hypothetical protein
22	PMI_RS12225	2699417..2700052 [-], 636	754062052	DUF4400 domain-containing protein
23	PMI_RS12230	2700039..2700599 [-], 561	501336752	hypothetical protein
24	PMI_RS12235 (traD)	2700609..2702429 [-], 1821	501336753	conjugative transfer system coupling protein TraD	TraD_F
25	PMI_RS12240	2702478..2704628 [-], 2151	501336754	TraI domain-containing protein	TraI_F
26	PMI_RS12245	2704877..2707003 [-], 2127	754062158	DEAD/DEAH box helicase

Genes in the 5-Kb flanking regions if available, or non-essential genes in the T4SS gene cluster if any.

Download FASTA format files

Proteins        Genes

This T4SS is encoded by the integrative and conjugative element (ICE) ICEPmiUSA1 and is thought to contribute to the transfer of this element. (click on the ICE name to view the detail ICE informaion in ICEberg, an ICE database)

(1) Flannery EL; Antczak SM; Mobley HL (2011). Self-transmissibility of the integrative and conjugative element ICEPm1 between clinical isolates requires a functional integrase, relaxase, and type IV secretion system. J Bacteriol. 193(16):4104-12. [PudMed:21665966]

(2) Pearson MM; Sebaihia M; Churcher C; Quail MA; Seshasayee AS; Luscombe NM; Abdellah Z; Arrosmith C; Atkin B; Chillingworth T; Hauser H; Jagels K; Moule S; Mungall K; Norbertczak H; Rabbinowitsch E; Walker D; Whithead S; Thomson NR; Rather PN; Parkhill J; Mobley HL (2008). Complete genome sequence of uropathogenic Proteus mirabilis, a master of both adherence and motility. J Bacteriol. 190(11):4027-37. [PudMed:18375554]

This literature contains experimental investigation