SecReT4
T4SS ID231
StrainBartonella clarridgeiae 73
Repliconchromosome [Browse all T4SS(s) in this replicon]
AccessionNC_014932
Location704616..713443
NameVirB
Functioneffector translocation
ClassificationType IVA; Type P
sequence This T4SS has been mentioned in a genome sequencing report.
structure Information of structure: structureBep9

T4SS components
ComponentVirB1VirB2VirB3VirB4VirB5VirB6VirB7VirB8VirB9
Number011111111
ComponentVirB10VirB11VirD4
Number110

The information of T4SS components from NC_014932
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductComponent
1BARCL_0637700194..700322 [+], 129319898805hypothetical protein 
2BARCL_0638700354..700560 [-], 207319898806hypothetical protein 
3BARCL_0639700743..702665 [-], 1923319898807Bartonella effector protein (Bep); substrate of VirB T4SS 
4BARCL_0640702829..704481 [-], 1653319898808Bartonella effector protein (Bep); substrate of VirB T4SS 
5BARCL_0641 (virB11)704616..705686 [-], 1071319898809type IV secretion system protein VirB11  VirB11
6BARCL_0642 (virB10)705683..706963 [-], 1281319898810type IV secretion system protein VirB10  VirB10
7BARCL_0643 (virB9)706960..707820 [-], 861319898811type IV secretion system protein VirB9 protein  VirB9
8BARCL_0644 (virB8)707817..708500 [-], 684319898812type IV secretion system protein VirB8  VirB8
9BARCL_0645 (virB7)708475..708801 [-], 327319898813type IV secretion system protein VirB7, 15 kDa Antigen  VirB7
10BARCL_0646 (virB6)708991..709983 [-], 993319898814type IV secretion system protein VirB6  VirB6
11BARCL_0647 (virB5)709989..710459 [-], 471319898815type IV secretion system protein VirB5 ; 17-kDa antigen  VirB5
12BARCL_0648 (virB4)710420..712774 [-], 2355319898816type IV secretion system protein VirB4  VirB4
13BARCL_0649 (virB3)712784..713092 [-], 309319898817type IV secretion system protein VirB3  VirB3
14BARCL_0650 (virB2)713093..713443 [-], 351319898818type IV secretion system protein VirB2  VirB2
15BARCL_0651713795..714559 [+], 765319898819hypothetical protein 
16BARCL_0652 (glnA)714851..716260 [-], 1410319898820glutamine synthetase 
17BARCL_0653 (glnB)716317..716661 [-], 345319898821nitrogen regulatory protein P-II 
 
flank Genes in the 5-Kb flanking regions if available, or non-essential genes in the T4SS gene cluster if any.

Download FASTA format files
Proteins        Genes

Effectors
BepA, BepB, BepA, Bep9

The information of protein effectors
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProduct  *
1BARCL_0635 698179..699882 [-], 1704319898804Bartonella effector protein (Bep); substrate of VirB T4SS  BepA
2BARCL_0639 700743..702665 [-], 1923319898807Bartonella effector protein (Bep); substrate of VirB T4SS  BepB
3BARCL_0640 702829..704481 [-], 1653319898808Bartonella effector protein (Bep); substrate of VirB T4SS  BepA
4BARCL_1032 1147413..1148168 [+], 756319899191Bartonella effector protein (Bep); substrate of VirB T4SSexperimental  Bep9
experimental T4SE derived from experimental literature.

Download FASTA format files
Proteins        Genes
The information on structure of this T4ss

#NameImageResourceDetailReference
1Bep94YK2 PDB (4YK2)Crystal Structure of the BID Domain of Bep9 from Bartonella clarridgeiae.(1) PubMed: 27889208
(1) Stanger FV et al. (2017). The BID Domain of Type IV Secretion Substrates Forms a Conserved Four-Helix Bundle Topped with a Hook. Structure. 25(1):203-211. [PudMed:27889208] experimental
(1) Engel P; Salzburger W; Liesch M; Chang CC; Maruyama S; Lanz C; Calteau A; Lajus A; Medigue C; Schuster SC; Dehio C (2011). Parallel evolution of a type IV secretion system in radiating lineages of the host-restricted bacterial pathogen Bartonella. PLoS Genet. 7(2):e1001296. [PudMed:21347280] experimental in_silico
 
experimental This literature contains experimental investigation
in_silico This literature contains bioinformatics investigation