 T4SS ID | 231 |
| Strain | Bartonella clarridgeiae 73 |
| Replicon | chromosome [Browse all T4SS(s) in this replicon] |
| Accession | NC_014932 |
| Location | 704616..713443 |
| Name | VirB |
| Function | effector translocation |
| Classification | Type IVA; Type P |
 This T4SS has been mentioned in a genome sequencing report. | |
Information of structure: 
T4SS components |
| Component | VirB1 | VirB2 | VirB3 | VirB4 | VirB5 | VirB6 | VirB7 | VirB8 | VirB9 |
| Number | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
| Component | VirB10 | VirB11 | VirD4 | ||||||
| Number | 1 | 1 | 0 |
The information of T4SS components from NC_014932 | ||||||
 | ||||||
| # | Locus tag (Gene) | Coordinates [+/-], size (bp) | Protein GI | Product | Component | |
| 1 | BARCL_0637 | 700194..700322 [+], 129 | 319898805 | hypothetical protein | ||
| 2 | BARCL_0638 | 700354..700560 [-], 207 | 319898806 | hypothetical protein | ||
| 3 | BARCL_0639 | 700743..702665 [-], 1923 | 319898807 | Bartonella effector protein (Bep); substrate of VirB T4SS | ||
| 4 | BARCL_0640 | 702829..704481 [-], 1653 | 319898808 | Bartonella effector protein (Bep); substrate of VirB T4SS | ||
| 5 | BARCL_0641 (virB11) | 704616..705686 [-], 1071 | 319898809 | type IV secretion system protein VirB11 | VirB11 | |
| 6 | BARCL_0642 (virB10) | 705683..706963 [-], 1281 | 319898810 | type IV secretion system protein VirB10 | VirB10 | |
| 7 | BARCL_0643 (virB9) | 706960..707820 [-], 861 | 319898811 | type IV secretion system protein VirB9 protein | VirB9 | |
| 8 | BARCL_0644 (virB8) | 707817..708500 [-], 684 | 319898812 | type IV secretion system protein VirB8 | VirB8 | |
| 9 | BARCL_0645 (virB7) | 708475..708801 [-], 327 | 319898813 | type IV secretion system protein VirB7, 15 kDa Antigen | VirB7 | |
| 10 | BARCL_0646 (virB6) | 708991..709983 [-], 993 | 319898814 | type IV secretion system protein VirB6 | VirB6 | |
| 11 | BARCL_0647 (virB5) | 709989..710459 [-], 471 | 319898815 | type IV secretion system protein VirB5 ; 17-kDa antigen | VirB5 | |
| 12 | BARCL_0648 (virB4) | 710420..712774 [-], 2355 | 319898816 | type IV secretion system protein VirB4 | VirB4 | |
| 13 | BARCL_0649 (virB3) | 712784..713092 [-], 309 | 319898817 | type IV secretion system protein VirB3 | VirB3 | |
| 14 | BARCL_0650 (virB2) | 713093..713443 [-], 351 | 319898818 | type IV secretion system protein VirB2 | VirB2 | |
| 15 | BARCL_0651 | 713795..714559 [+], 765 | 319898819 | hypothetical protein | ||
| 16 | BARCL_0652 (glnA) | 714851..716260 [-], 1410 | 319898820 | glutamine synthetase | ||
| 17 | BARCL_0653 (glnB) | 716317..716661 [-], 345 | 319898821 | nitrogen regulatory protein P-II | ||
 Genes in the 5-Kb flanking regions if available, or non-essential genes in the T4SS gene cluster if any. |
Download FASTA format files |
| Proteins Genes |
Effectors |
| BepA, BepB, BepA, Bep9 |
The information of protein effectors | ||||||
| # | Locus tag (Gene) | Coordinates [+/-], size (bp) | Protein GI | Product | * | |
| 1 | BARCL_0635 | 698179..699882 [-], 1704 | 319898804 | Bartonella effector protein (Bep); substrate of VirB T4SS | BepA | |
| 2 | BARCL_0639 | 700743..702665 [-], 1923 | 319898807 | Bartonella effector protein (Bep); substrate of VirB T4SS | BepB | |
| 3 | BARCL_0640 | 702829..704481 [-], 1653 | 319898808 | Bartonella effector protein (Bep); substrate of VirB T4SS | BepA | |
| 4 | BARCL_1032 | 1147413..1148168 [+], 756 | 319899191 | Bartonella effector protein (Bep); substrate of VirB T4SS |  Bep9 | |
T4SE derived from experimental literature.Download FASTA format files |
| Proteins Genes |
| # | Name | Image | Resource | Detail | Reference |
| 1 | Bep9 |  | PDB (4YK2) | Crystal Structure of the BID Domain of Bep9 from Bartonella clarridgeiae. | (1) PubMed: 27889208 |
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(1) Stanger FV et al. (2017). The BID Domain of Type IV Secretion Substrates Forms a Conserved Four-Helix Bundle Topped with a Hook. Structure. 25(1):203-211. [PudMed:27889208]
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(1) Engel P; Salzburger W; Liesch M; Chang CC; Maruyama S; Lanz C; Calteau A; Lajus A; Medigue C; Schuster SC; Dehio C (2011). Parallel evolution of a type IV secretion system in radiating lineages of the host-restricted bacterial pathogen Bartonella. PLoS Genet. 7(2):e1001296. [PudMed:21347280] 
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| This literature contains experimental investigation |
| This literature contains bioinformatics investigation |