Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   M036_RS16215 Genome accession   NZ_CP005997
Coordinates   3097343..3097987 (-) Length   214 a.a.
NCBI ID   WP_003220716.1    Uniprot ID   G4P056
Organism   Bacillus subtilis TO-A     
Function   promoting transcription of comS (predicted from homology)   
Competence regulation

Genomic Context

Location: 3092343..3102987
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M036_RS16180 (M036_16150) mrpB 3093535..3093966 (+) 432 WP_003228819.1 Na(+)/H(+) antiporter subunit B -
  M036_RS16185 (M036_16155) mrpC 3093966..3094307 (+) 342 WP_003220730.1 Na(+)/H(+) antiporter subunit C -
  M036_RS16190 (M036_16160) mrpD 3094300..3095781 (+) 1482 WP_003228817.1 Na+/H+ antiporter subunit D -
  M036_RS16195 (M036_16165) mrpE 3095787..3096263 (+) 477 WP_003228815.1 Na+/H+ antiporter subunit E -
  M036_RS16200 (M036_16170) mrpF 3096263..3096547 (+) 285 WP_003228814.1 Na(+)/H(+) antiporter subunit F1 -
  M036_RS16205 (M036_16175) mnhG 3096531..3096905 (+) 375 WP_003228812.1 monovalent cation/H(+) antiporter subunit G -
  M036_RS16210 (M036_16180) yuxO 3096944..3097324 (-) 381 WP_003228810.1 hotdog fold thioesterase -
  M036_RS16215 (M036_16185) comA 3097343..3097987 (-) 645 WP_003220716.1 two-component system response regulator ComA Regulator
  M036_RS16220 (M036_16190) - 3098068..3100365 (-) 2298 Protein_3146 histidine kinase -
  M036_RS16225 (M036_16195) comX 3100373..3100534 (-) 162 WP_003228803.1 competence pheromone ComX -
  M036_RS16230 (M036_16200) comQ 3100549..3101409 (-) 861 WP_029318489.1 polyprenyl synthetase family protein Regulator
  M036_RS16235 (M036_16205) degQ 3101594..3101734 (-) 141 WP_003220708.1 degradation enzyme regulation protein DegQ Regulator
  M036_RS21830 - 3101956..3102081 (+) 126 WP_003228793.1 hypothetical protein -
  M036_RS16240 (M036_16210) - 3102195..3102563 (+) 369 WP_014477834.1 hypothetical protein -

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 24128.51 Da        Isoelectric Point: 4.6857

>NTDB_id=99990 M036_RS16215 WP_003220716.1 3097343..3097987(-) (comA) [Bacillus subtilis TO-A]
MKKILVIDDHPAVMEGTKTILETDSNLSVDCLSPEPSEQFIKQHDFSSYDLILMDLNLGGEVNGMELSKQILQENPHCKI
IVYTGYEVEDYFEEAIRAGLHGAISKTESKEKITQYIYHVLNGEILVDFAYFKQLMTQQKTKPAPSSQKEQDVLTPRECL
ILQEVEKGFTNQEIADALHLSKRSIEYSLTSIFNKLNVGSRTEAVLIAKSDGVL

Nucleotide


Download         Length: 645 bp        

>NTDB_id=99990 M036_RS16215 WP_003220716.1 3097343..3097987(-) (comA) [Bacillus subtilis TO-A]
ATGAAAAAGATACTAGTGATTGATGACCATCCGGCTGTCATGGAAGGCACCAAGACAATTTTGGAAACGGATTCGAATTT
GTCTGTTGATTGTCTCAGTCCTGAACCGAGCGAACAGTTTATCAAGCAGCATGATTTCTCGTCATATGATCTCATTTTAA
TGGATCTGAATCTAGGCGGCGAGGTCAATGGGATGGAGCTTTCTAAACAGATTTTACAAGAGAATCCTCATTGTAAAATT
ATCGTGTATACCGGTTATGAGGTCGAGGATTATTTCGAGGAAGCGATTCGTGCGGGTCTGCACGGTGCCATCAGCAAAAC
GGAATCTAAAGAAAAGATCACCCAATACATATACCACGTACTCAACGGAGAAATTTTAGTCGATTTTGCTTACTTTAAAC
AGCTGATGACTCAGCAAAAAACAAAGCCGGCTCCTTCCTCTCAAAAAGAACAAGATGTGCTCACACCTAGAGAATGCCTG
ATTCTTCAAGAAGTTGAAAAGGGATTTACAAACCAAGAAATCGCAGATGCCCTTCATTTAAGCAAGCGGTCCATTGAATA
CAGCTTGACATCGATTTTCAATAAGCTGAATGTCGGTTCACGGACGGAAGCGGTTTTGATTGCGAAATCAGACGGTGTAC
TTTAA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(152-208)

Response regulator receiver domain (Response_reg)

(4-117)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB G4P056

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Bacillus subtilis subsp. subtilis str. 168

100

100

1

Multiple sequence alignment