Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   EL076_RS00360 Genome accession   NZ_LR134275
Coordinates   62585..64528 (+) Length   647 a.a.
NCBI ID   WP_126428893.1    Uniprot ID   -
Organism   Streptococcus vestibularis strain NCTC12167     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 57585..69528
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL076_RS00330 (NCTC12167_00066) argR 57790..58218 (+) 429 WP_170314548.1 arginine repressor -
  EL076_RS00335 (NCTC12167_00067) - 58218..58577 (+) 360 WP_002889586.1 YlbF family regulator -
  EL076_RS00340 (NCTC12167_00068) hexA 58597..61128 (+) 2532 WP_408055270.1 DNA mismatch repair protein MutS Machinery gene
  EL076_RS00345 (NCTC12167_00069) - 61162..61617 (-) 456 WP_126428891.1 DUF3021 domain-containing protein -
  EL076_RS00350 (NCTC12167_00070) - 61614..62051 (-) 438 WP_164555384.1 LytTR family DNA-binding domain-containing protein -
  EL076_RS00355 (NCTC12167_00071) - 62230..62535 (+) 306 WP_003094956.1 hypothetical protein -
  EL076_RS00360 (NCTC12167_00072) hexB 62585..64528 (+) 1944 WP_126428893.1 DNA mismatch repair endonuclease MutL Machinery gene
  EL076_RS00365 (NCTC12167_00073) - 64659..64880 (+) 222 WP_002886321.1 hypothetical protein -
  EL076_RS00370 (NCTC12167_00074) ruvA 65038..65628 (+) 591 WP_002886323.1 Holliday junction branch migration protein RuvA Machinery gene
  EL076_RS00375 (NCTC12167_00075) - 65637..66191 (+) 555 WP_002886325.1 DNA-3-methyladenine glycosylase I -
  EL076_RS00380 (NCTC12167_00076) cinA 66288..67559 (+) 1272 WP_003094929.1 competence/damage-inducible protein A Machinery gene
  EL076_RS00385 (NCTC12167_00077) recA 67595..68734 (+) 1140 WP_003094936.1 recombinase RecA Machinery gene
  EL076_RS00390 (NCTC12167_00078) spx 68911..69309 (+) 399 WP_003094927.1 transcriptional regulator Spx -

Sequence

Protein


Download         Length: 647 a.a.        Molecular weight: 72579.61 Da        Isoelectric Point: 5.1377

>NTDB_id=999650 EL076_RS00360 WP_126428893.1 62585..64528(+) (hexB) [Streptococcus vestibularis strain NCTC12167]
MTKIIELPEVLANQIAAGEVVERPASVVKELVENAIDAGSTQITIEVEESGLSKIQITDNGEGMAQADVAMSLRRHATSK
IKNQGDLFRIRTLGFRGEALPSIASISHLTIVTAADGEAYGTKLVAKAGEIESQDPISTPVGTKITVENLFYNTPARLKY
MKSLQAELAHIVDVVNRLSLAHPEVAFTLLNDGRQLTQTSGTGDLRQAIAGIYGLTTAKKMVEISNSDLDFEVSGYVSLP
ELTRANRNYITILINGRYIKNFLLNRAIFDGYGSKLMVGRFPIAVIDIQIDPYLADVNVHPTKQEVRISKEKELMALISS
AIAQSLREQDLIPDALENLAKSSTRGAAKPVQTSLPLKQTNLYYDSSRNDFFVKPETVQEDIKPLISESESPVSSVENKP
QPSVKQAQRSVDESDDEHEKLDYKNKSKMKRMLETLDNEETSTFPELEFFGQMHGTYLFAQGQGGLYIIDQHAAQERVKY
EYYREKIGEVDSSLQQLLVPYLFEFSGSDYISLQEKMSLLNQVGIYLEPYGNNTFILREHPIWMKEEEIESAVYEMCDML
LLTNEVSVKTYRAELAIMMSCKRSIKANHALDDYSARDLLVQLAQCKNPYNCPHGRPVLVNFTKSDMEKMFRRIQENHTS
LRDLGKY

Nucleotide


Download         Length: 1944 bp        

>NTDB_id=999650 EL076_RS00360 WP_126428893.1 62585..64528(+) (hexB) [Streptococcus vestibularis strain NCTC12167]
ATGACAAAAATCATCGAATTGCCTGAGGTGTTAGCCAACCAGATTGCTGCTGGTGAGGTCGTAGAGCGCCCAGCCAGTGT
TGTCAAAGAGTTGGTGGAAAATGCTATTGATGCCGGTAGCACTCAGATTACCATTGAAGTTGAAGAATCAGGTCTCTCAA
AAATTCAAATCACAGACAATGGCGAAGGAATGGCTCAAGCTGATGTGGCCATGAGTTTGCGCCGTCATGCAACAAGTAAA
ATCAAAAATCAAGGAGATCTCTTTCGTATTCGGACCCTTGGTTTTCGAGGTGAGGCTCTGCCCTCTATAGCTTCTATCAG
TCATCTAACTATTGTGACAGCAGCGGATGGAGAAGCCTATGGGACTAAACTGGTTGCTAAAGCTGGAGAAATTGAGAGTC
AGGATCCTATTTCAACACCAGTTGGAACAAAGATTACCGTTGAAAATCTATTTTATAACACCCCAGCTCGTCTCAAGTAT
ATGAAGAGTTTACAGGCTGAGTTGGCTCATATTGTTGATGTTGTTAATCGTCTGAGTCTAGCTCATCCCGAGGTTGCCTT
TACCTTGCTTAATGATGGTCGTCAGTTGACACAGACATCAGGTACTGGAGACCTCCGTCAAGCTATTGCTGGTATTTATG
GTTTGACAACGGCTAAAAAAATGGTGGAGATTTCAAATTCTGACCTTGATTTTGAAGTTTCTGGATATGTTAGTCTCCCT
GAGTTAACCCGTGCGAATCGTAACTACATCACGATTCTCATTAATGGACGCTATATAAAAAACTTCCTGCTTAACCGTGC
CATTTTTGATGGTTATGGTTCTAAACTCATGGTAGGACGCTTCCCTATTGCAGTTATTGATATTCAGATTGATCCCTACT
TGGCCGATGTCAATGTTCACCCAACAAAGCAGGAAGTACGTATCTCTAAAGAAAAAGAGCTCATGGCCCTTATCAGCTCA
GCCATTGCTCAAAGCCTTAGAGAGCAGGATTTGATTCCTGATGCCCTTGAAAATTTGGCCAAGTCTAGTACCAGAGGTGC
AGCTAAGCCAGTTCAAACCAGTCTTCCACTCAAACAAACCAATCTTTACTATGATAGCAGTCGTAATGATTTTTTTGTCA
AACCAGAGACCGTCCAAGAGGATATCAAACCTCTTATATCGGAGTCAGAGTCTCCAGTTTCATCGGTAGAAAACAAACCA
CAACCTTCTGTTAAACAGGCACAACGTTCAGTAGATGAAAGTGATGACGAACACGAAAAACTTGATTATAAAAACAAGTC
GAAAATGAAGCGCATGCTTGAAACTTTGGATAATGAGGAAACATCAACCTTCCCTGAGTTGGAGTTTTTTGGTCAAATGC
ATGGAACCTATCTCTTTGCGCAAGGACAAGGTGGACTTTACATCATTGACCAACATGCTGCTCAAGAACGTGTCAAGTAT
GAGTACTATCGTGAAAAGATCGGTGAGGTTGACAGCAGTCTACAACAGCTCTTGGTTCCCTATCTCTTTGAATTTTCAGG
TTCAGATTACATTAGTTTACAAGAAAAAATGTCCCTTCTGAACCAGGTTGGTATCTATTTAGAGCCTTATGGGAATAACA
CCTTCATTCTTCGTGAACATCCTATCTGGATGAAGGAAGAAGAGATTGAATCAGCGGTCTATGAAATGTGTGACATGCTT
CTTTTGACGAATGAAGTGTCTGTCAAGACCTACCGTGCTGAGCTAGCCATCATGATGAGTTGTAAACGTTCAATCAAGGC
TAATCATGCACTTGATGATTACTCTGCGCGTGACCTCCTAGTACAGCTTGCACAGTGTAAAAATCCCTACAATTGCCCTC
ACGGACGTCCAGTACTTGTCAACTTTACCAAGTCTGATATGGAAAAAATGTTCCGTCGTATCCAAGAAAATCATACAAGT
CTACGTGACCTAGGGAAGTATTAA

Domains

Predicted by InterProScan.

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(209-326)

MutL C terminal dimerisation domain (MutL_C)

(448-591)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-128)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

69.207

100

0.702