Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpE   Type   Regulator
Locus tag   EL086_RS08340 Genome accession   NZ_LR134274
Coordinates   1813279..1815384 (-) Length   701 a.a.
NCBI ID   WP_038676649.1    Uniprot ID   -
Organism   Streptococcus salivarius strain NCTC8618     
Function   repress competence development (at the early growth phase) (predicted from homology)   
Competence regulation

Genomic Context

Location: 1808279..1820384
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL086_RS08310 (NCTC8618_04091) pptB 1808624..1809658 (-) 1035 WP_371212501.1 ABC transporter permease Regulator
  EL086_RS08315 (NCTC8618_04092) pptA 1809658..1810389 (-) 732 WP_038676648.1 ABC transporter ATP-binding protein Regulator
  EL086_RS08320 (NCTC8618_04093) - 1810454..1810873 (+) 420 WP_002891660.1 HIT family protein -
  EL086_RS08325 (NCTC8618_04094) - 1810870..1811169 (+) 300 WP_002884229.1 hypothetical protein -
  EL086_RS10450 (NCTC8618_04095) - 1811349..1811516 (-) 168 WP_002884708.1 hypothetical protein -
  EL086_RS10500 (NCTC8618_04096) - 1811534..1811998 (-) 465 WP_172855709.1 hypothetical protein -
  EL086_RS08335 (NCTC8618_04097) - 1812092..1812700 (-) 609 WP_002884297.1 DUF4230 domain-containing protein -
  EL086_RS10665 (NCTC8618_04098) - 1812718..1812843 (-) 126 WP_002884447.1 hypothetical protein -
  EL086_RS08340 (NCTC8618_04099) clpE 1813279..1815384 (-) 2106 WP_038676649.1 AAA family ATPase Regulator
  EL086_RS08345 (NCTC8618_04102) - 1816117..1817208 (-) 1092 WP_038676651.1 nucleotidyltransferase -
  EL086_RS08350 (NCTC8618_04103) - 1817215..1817955 (-) 741 WP_013991077.1 class I SAM-dependent DNA methyltransferase -
  EL086_RS08355 (NCTC8618_04104) rsfS 1818274..1818627 (-) 354 WP_014632696.1 ribosome silencing factor -
  EL086_RS08360 (NCTC8618_04105) yqeK 1818651..1819241 (-) 591 WP_038676655.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  EL086_RS08365 (NCTC8618_04106) - 1819238..1819870 (-) 633 WP_002884372.1 nicotinate-nucleotide adenylyltransferase -
  EL086_RS08370 (NCTC8618_04107) yhbY 1819978..1820295 (-) 318 WP_002884193.1 ribosome assembly RNA-binding protein YhbY -

Sequence

Protein


Download         Length: 701 a.a.        Molecular weight: 77347.30 Da        Isoelectric Point: 4.7718

>NTDB_id=999613 EL086_RS08340 WP_038676649.1 1813279..1815384(-) (clpE) [Streptococcus salivarius strain NCTC8618]
MNNNFNNMDDLFNQLMGNMGGYRSENRRYMINGREVTPEEFAIYRQTGQLPGNEGEAVNPTQHQGKGPKQDGIIAKLGRN
LTEEAREGKLDPVIGRNKEIQEACEILARRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGLEA
GTQYRGSFEENIQNLVNEVKEAGNIILFFDEIHQILGAGSTGDGQGSKGLADILKPALSRGELTVIGATTQDEYRNTILK
NAALARRFNEVKVNAPSAEDTFKILQGIRDLYEKHHNVILPDDVLKAAVDFSVQYIPQRSLPDKAIDLVDVTAAHLAAQH
PVTDVNAVEHEIEEEKAKQEAAAAKEDYEAALNAKVRIEELEKKIANHTADLKVTATVNDVAESVERMTGIPVSQMGATD
IERLKDMGHRLQTKVIGQDKAVEAVARAIRRNRAGFDEGNRPIGSFLFVGPTGVGKTELAKQLALDMFGTKDAIIRLDMS
EYSDRTAVSKLIGTTAGYVGYDDNSNTLTERVRRNPYSIVLLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNTVI
IATSNAGFGYEANLTEDADKPELMDRLKPYFRPEFLNRFNAVIEFSHLSKEDLSKIVDLMLVEVNKTLSKKDIDLAVSEA
AKEYMTEEGYDEVMGVRPLRRVVEQQIRDKVTDFHLDNLDAKHLEADMEDGILVIKEKDAK

Nucleotide


Download         Length: 2106 bp        

>NTDB_id=999613 EL086_RS08340 WP_038676649.1 1813279..1815384(-) (clpE) [Streptococcus salivarius strain NCTC8618]
ATGAACAACAACTTTAACAATATGGATGATCTTTTCAATCAATTGATGGGTAACATGGGTGGTTACCGTTCAGAAAACCG
TCGCTACATGATTAACGGTCGTGAAGTGACACCTGAAGAATTTGCTATCTACCGTCAAACAGGTCAATTGCCTGGTAATG
AAGGTGAAGCAGTGAACCCAACTCAACATCAAGGTAAAGGACCTAAACAAGATGGTATTATTGCTAAACTTGGTCGTAAC
TTGACTGAAGAAGCTCGTGAAGGTAAATTGGATCCTGTTATCGGACGTAACAAAGAAATCCAAGAAGCTTGCGAAATCTT
GGCTCGTCGTACCAAGAATAACCCAGTCCTTGTCGGGGATGCTGGGGTTGGTAAAACAGCCGTAGTTGAAGGTTTGGCTC
AAGCCATCGTCAATGGTGATGTCCCAGCTGCTATCAAGAATAAAGAAATCATTTCAATTGATATTTCTGGACTTGAAGCT
GGTACTCAATACCGTGGTAGCTTTGAAGAAAACATTCAAAACTTGGTAAACGAAGTCAAAGAAGCTGGAAACATTATCCT
CTTCTTCGATGAAATCCACCAAATTCTTGGTGCCGGAAGCACTGGTGATGGTCAAGGGTCTAAAGGTCTTGCTGATATCT
TGAAACCAGCTCTTTCACGTGGTGAATTGACAGTGATTGGTGCAACAACTCAAGATGAATATCGTAACACTATCTTGAAG
AACGCTGCCCTAGCTCGTCGTTTCAACGAAGTTAAGGTCAATGCTCCTTCTGCTGAAGATACTTTCAAGATTCTCCAAGG
TATCCGTGATCTTTATGAAAAACACCACAATGTTATCTTGCCAGATGATGTTTTGAAGGCAGCGGTAGATTTCTCTGTAC
AATACATTCCACAACGTAGCTTGCCAGATAAGGCTATCGACCTTGTCGATGTAACAGCTGCTCACTTGGCTGCTCAACAC
CCAGTGACTGATGTGAATGCTGTTGAACATGAAATTGAAGAAGAAAAAGCTAAACAAGAAGCTGCAGCTGCCAAAGAAGA
CTACGAAGCAGCTCTAAACGCTAAGGTTCGTATTGAAGAACTTGAAAAGAAAATTGCTAACCATACAGCAGACCTTAAAG
TCACTGCAACTGTTAACGATGTGGCTGAATCTGTAGAACGTATGACTGGTATTCCAGTATCGCAAATGGGAGCAACTGAT
ATCGAACGTTTGAAAGATATGGGCCACCGTTTGCAAACTAAAGTTATCGGTCAAGATAAAGCCGTTGAAGCAGTGGCACG
TGCCATCCGTCGTAACCGTGCAGGATTTGACGAAGGTAACCGTCCAATTGGTAGCTTCCTCTTTGTAGGACCTACTGGTG
TTGGTAAAACTGAGTTGGCTAAACAATTGGCTCTTGATATGTTCGGAACTAAAGATGCTATTATCCGTTTGGACATGTCA
GAATATAGCGACCGCACAGCCGTTTCTAAATTGATTGGTACAACAGCTGGTTATGTTGGTTATGATGACAATAGCAATAC
TTTGACAGAACGTGTTCGCCGTAACCCATACTCAATCGTTCTTCTCGACGAAATTGAAAAGGCTGACCCTCAAGTCATCA
CCCTTCTCCTCCAAGTTTTGGACGATGGTCGTTTGACAGATGGTCAAGGTAACACTGTAAACTTCAAGAATACTGTGATT
ATTGCAACTTCAAACGCAGGCTTTGGTTACGAAGCTAACTTGACAGAAGATGCTGATAAACCAGAACTTATGGATCGTTT
GAAACCTTACTTCCGTCCAGAATTCCTTAACCGCTTCAATGCTGTCATCGAATTCTCACACTTGAGCAAAGAAGATCTTT
CTAAGATTGTAGACCTTATGTTGGTTGAAGTTAACAAGACGCTTTCTAAGAAAGACATTGACTTGGCAGTTAGCGAAGCT
GCTAAAGAATACATGACTGAAGAAGGCTACGATGAAGTCATGGGTGTTCGTCCACTCCGTCGTGTGGTTGAACAACAAAT
CCGTGACAAAGTCACAGACTTCCACTTGGATAACCTTGATGCTAAACACCTAGAAGCTGATATGGAAGATGGTATCTTGG
TTATCAAAGAAAAAGATGCTAAATAA

Domains

Predicted by InterProScan.

AAA domain (Cdc48 subfamily) (AAA_2)

(441-601)

AAA lid domain (AAA_lid_9)

(257-351)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(608-678)

ATPase family associated with various cellular activities (AAA) (AAA)

(116-248)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpE Streptococcus mutans UA159

46.505

100

0.465
  clpC Lactococcus lactis subsp. cremoris KW2

48.848

92.867

0.454
  clpE Streptococcus pneumoniae Rx1

48.523

91.726

0.445
  clpE Streptococcus pneumoniae TIGR4

48.523

91.726

0.445
  clpE Streptococcus pneumoniae R6

48.523

91.726

0.445
  clpE Streptococcus pneumoniae D39

48.523

91.726

0.445
  clpC Bacillus subtilis subsp. subtilis str. 168

45.723

91.726

0.419
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

42.089

92.867

0.391
  clpC Streptococcus thermophilus LMD-9

43.274

88.017

0.381
  clpC Streptococcus pneumoniae Rx1

43.322

87.589

0.379
  clpC Streptococcus pneumoniae D39

43.322

87.589

0.379
  clpC Streptococcus pneumoniae TIGR4

43.322

87.589

0.379
  clpC Streptococcus thermophilus LMG 18311

42.811

88.302

0.378
  clpC Streptococcus mutans UA159

42.173

89.301

0.377

Multiple sequence alignment