Detailed information NTG0999478

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: ABFJ88_RS14015
• Genome accession: NZ_CP155815
• Coordinates: 2775371..2776258 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143425.1
• Uniprot ID: A0A389PV50
• Organism: Staphylococcus aureus strain CUBIST-17
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2770371..2781258

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ABFJ88_RS13985 (ABFJ88_14005)	-	2770390..2770482 (+)	93	WP_010956583.1	hypothetical protein	-
ABFJ88_RS13990 (ABFJ88_14010)	-	2770590..2771087 (-)	498	WP_001065268.1	glutathione peroxidase	-
ABFJ88_RS13995 (ABFJ88_14015)	-	2771097..2771357 (-)	261	WP_001791974.1	hypothetical protein	-
ABFJ88_RS14000 (ABFJ88_14020)	-	2771739..2771852 (-)	114	Protein_2720	hypothetical protein	-
ABFJ88_RS14005 (ABFJ88_14025)	-	2772511..2774511 (-)	2001	WP_000776751.1	ABC transporter permease	-
ABFJ88_RS14010 (ABFJ88_14030)	-	2774508..2775263 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
ABFJ88_RS14015 (ABFJ88_14035)	braS	2775371..2776258 (-)	888	WP_000143425.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
ABFJ88_RS14020 (ABFJ88_14040)	braR	2776269..2776934 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
ABFJ88_RS14025 (ABFJ88_14045)	-	2776960..2777160 (-)	201	WP_000604730.1	hypothetical protein	-
ABFJ88_RS14030 (ABFJ88_14050)	-	2777358..2778782 (+)	1425	WP_000953755.1	alkaline phosphatase	-
ABFJ88_RS14035	-	2778842..2778943 (-)	102	WP_000731976.1	SE2200 family small protein	-
ABFJ88_RS14040 (ABFJ88_14060)	-	2779065..2779520 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
ABFJ88_RS14045 (ABFJ88_14065)	-	2779765..2780526 (-)	762	WP_000323441.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34006.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=999478 ABFJ88_RS14015 WP_000143425.1 2775371..2776258(-) (braS) [Staphylococcus aureus strain CUBIST-17]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLETALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=999478 ABFJ88_RS14015 WP_000143425.1 2775371..2776258(-) (braS) [Staphylococcus aureus strain CUBIST-17]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAACTGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A389PV50

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	100	100	1