Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   EL071_RS03100 Genome accession   NZ_LR134265
Coordinates   595679..597652 (-) Length   657 a.a.
NCBI ID   WP_164993767.1    Uniprot ID   -
Organism   Streptococcus agalactiae strain NCTC8184     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 590679..602652
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL071_RS03075 (NCTC8184_00595) recA 590688..591827 (-) 1140 WP_115356507.1 recombinase RecA Machinery gene
  EL071_RS03080 (NCTC8184_00596) cinA 591901..593160 (-) 1260 WP_115356506.1 competence/damage-inducible protein A Machinery gene
  EL071_RS03085 (NCTC8184_00597) - 593249..593800 (-) 552 WP_115356505.1 DNA-3-methyladenine glycosylase I -
  EL071_RS03090 (NCTC8184_00598) ruvA 593823..594413 (-) 591 WP_000272490.1 Holliday junction branch migration protein RuvA Machinery gene
  EL071_RS03095 (NCTC8184_00599) - 594415..595647 (-) 1233 WP_164993766.1 MFS transporter -
  EL071_RS03100 (NCTC8184_00600) hexB 595679..597652 (-) 1974 WP_164993767.1 DNA mismatch repair endonuclease MutL Machinery gene
  EL071_RS03110 - 597878..598081 (+) 204 WP_000191849.1 cold shock domain-containing protein -
  EL071_RS03115 (NCTC8184_00602) hexA 598138..600714 (-) 2577 WP_115356503.1 DNA mismatch repair protein MutS Machinery gene
  EL071_RS03120 (NCTC8184_00603) argR 600771..601208 (-) 438 WP_001033152.1 arginine repressor -

Sequence

Protein


Download         Length: 657 a.a.        Molecular weight: 73850.02 Da        Isoelectric Point: 5.2843

>NTDB_id=999360 EL071_RS03100 WP_164993767.1 595679..597652(-) (hexB) [Streptococcus agalactiae strain NCTC8184]
MSKIIELPDILANQIAAGEVVERPSSVVKELVENAIDAGSSQITIEVEESGLKKIQITDNGEGMTSEDAVLSLRRHATSK
IKSQSDLFRIRTLGFRGEALPSIASISLMTIKTATEQGKQGTLLVAKGGNIEKQEVVSSPRGTKILVENLFFNTPARLKY
MKSLQSELAHIIDIVNRLSLAHPEVAFTLINDGKEMTKTSGTGDLRQAIAGIYGLNTAKKMIEISNADLDFEISGYVSLP
ELTRANRNYITLLINGRYIKNFLLNRSILDGYGSKLMVGRFPIAVIDIQIDPYLADVNVHPTKQEVRISKERELMSLISS
AISESLKQYDLIPDALENLAKTSTRSVDKPIQTSFSLKQPGLYYDRTKNDFFIDADTVSEPIANFTNLDKSDGSVDNDVK
NSVNQGAMQSPNIKYASRDQADSENFIHSQDYLSSKQSLNKLVEKLDSEESSTFPELEFFGQMHGTYLFAQGNGGLYIID
QHAAQERVKYEYYREKIGEVDNSLQQLLVPFLFEFSSSDFLQLQEKMSLLEDVGIFLEPYGNNTFILREHPIWMKEEEVE
SGVYEMCDMLLLTNEVSVKKYRAELAIMMSCKRSIKANHTLDDYSARHLLDQLAQCKNPYNCPHGRPVLVNFTKADMEKM
FKRIQENHTSLRDLGKY

Nucleotide


Download         Length: 1974 bp        

>NTDB_id=999360 EL071_RS03100 WP_164993767.1 595679..597652(-) (hexB) [Streptococcus agalactiae strain NCTC8184]
TTGTCTAAAATTATTGAATTACCGGATATATTAGCTAACCAGATTGCTGCTGGTGAGGTTGTTGAAAGACCTAGTAGCGT
CGTTAAAGAATTAGTTGAAAATGCCATAGATGCAGGAAGTAGCCAAATTACCATAGAGGTTGAAGAATCTGGTCTTAAAA
AGATTCAAATAACGGATAACGGTGAAGGGATGACTAGTGAGGATGCCGTTCTCAGTTTACGACGTCACGCTACATCCAAA
ATCAAAAGCCAGAGTGACCTTTTTCGTATTCGGACCTTAGGTTTTCGTGGTGAAGCTCTACCATCAATCGCTTCGATTAG
TTTAATGACGATAAAAACAGCTACAGAGCAAGGGAAACAAGGGACGTTACTTGTTGCTAAAGGGGGAAACATTGAAAAAC
AGGAAGTTGTTTCAAGTCCTCGTGGAACAAAAATTTTAGTTGAAAATTTATTCTTTAATACGCCTGCCAGATTGAAATAC
ATGAAGAGTTTACAGTCTGAACTAGCTCATATTATTGATATTGTTAATAGACTCAGTCTAGCGCATCCGGAAGTTGCTTT
TACACTGATAAATGATGGTAAAGAAATGACTAAAACTAGTGGGACTGGCGATTTGAGACAGGCGATTGCAGGTATTTATG
GTTTAAATACTGCAAAAAAAATGATTGAGATTTCAAATGCAGATTTAGATTTTGAAATTTCGGGTTATGTAAGTTTGCCT
GAATTGACACGAGCTAACCGAAACTATATTACCCTATTAATTAACGGTCGTTACATTAAAAATTTTCTTTTGAACCGCTC
AATTCTAGATGGTTATGGTTCAAAGTTGATGGTTGGAAGATTTCCAATTGCTGTCATTGATATTCAGATAGATCCTTATC
TAGCAGATGTCAACGTTCATCCGACTAAGCAAGAGGTGAGAATTTCTAAGGAACGAGAATTAATGAGTTTAATAAGCTCA
GCAATTTCTGAGAGTCTTAAACAATATGATTTGATTCCGGATGCTTTAGAGAATTTAGCTAAAACTAGTACCCGAAGTGT
AGATAAGCCTATACAAACAAGCTTCTCACTAAAACAGCCTGGTTTGTATTACGATAGGACTAAAAATGACTTTTTTATAG
ATGCAGATACTGTATCTGAACCTATTGCTAACTTTACAAACCTTGACAAAAGTGATGGTTCAGTTGACAATGATGTAAAA
AACTCTGTTAATCAAGGAGCAATGCAGTCTCCTAATATAAAGTATGCTAGTAGAGATCAAGCGGATAGTGAGAACTTCAT
TCATTCTCAAGATTACCTTAGTAGTAAACAGTCACTTAACAAACTTGTTGAAAAATTAGATTCGGAAGAAAGTTCGACTT
TTCCAGAGCTCGAATTTTTTGGTCAAATGCATGGGACCTACTTATTTGCTCAAGGGAATGGTGGGTTGTATATTATTGAT
CAACATGCAGCTCAAGAGCGTGTAAAATATGAGTATTACCGTGAAAAGATAGGTGAGGTTGATAATAGTCTTCAACAATT
GTTAGTACCATTTCTATTTGAATTTTCAAGTTCAGATTTTCTTCAATTACAAGAAAAAATGTCATTATTAGAAGATGTTG
GTATTTTCTTGGAACCGTATGGTAATAATACTTTCATTTTAAGGGAACATCCAATTTGGATGAAAGAAGAAGAGGTAGAG
TCTGGCGTTTATGAAATGTGTGATATGTTGTTGCTCACTAATGAAGTATCAGTGAAAAAATATCGCGCAGAGTTGGCTAT
TATGATGTCTTGCAAGCGATCTATTAAAGCAAACCATACGCTAGACGATTACTCAGCACGTCATTTATTAGATCAGTTAG
CGCAATGTAAAAATCCTTATAATTGCCCTCATGGAAGACCTGTTTTAGTTAATTTTACAAAAGCTGATATGGAGAAAATG
TTTAAACGAATCCAAGAAAATCATACAAGCCTCAGGGATTTAGGAAAATATTGA

Domains

Predicted by InterProScan.

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(209-326)

MutL C terminal dimerisation domain (MutL_C)

(458-601)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-121)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

69.149

100

0.693

Multiple sequence alignment