Detailed information    

insolico Bioinformatically predicted

Overview

Name   disA   Type   Machinery gene
Locus tag   M036_RS00525 Genome accession   NZ_CP005997
Coordinates   101400..102482 (+) Length   360 a.a.
NCBI ID   WP_003225736.1    Uniprot ID   P37573
Organism   Bacillus subtilis TO-A     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 96400..107482
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M036_RS00510 (M036_00500) mcsB 96408..97499 (+) 1092 WP_003235007.1 protein arginine kinase -
  M036_RS00515 (M036_00505) clpC 97496..99928 (+) 2433 WP_003235011.1 ATP-dependent protease ATP-binding subunit ClpC Regulator
  M036_RS00520 (M036_00510) radA/sms 100020..101396 (+) 1377 WP_004399687.1 DNA repair protein RadA Machinery gene
  M036_RS00525 (M036_00515) disA 101400..102482 (+) 1083 WP_003225736.1 DNA integrity scanning diadenylate cyclase DisA Machinery gene
  M036_RS00530 (M036_00520) yacL 102598..103698 (+) 1101 WP_003235014.1 PIN/TRAM domain-containing protein -
  M036_RS00535 (M036_00525) ispD 103713..104411 (+) 699 WP_003235019.1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase -
  M036_RS00540 (M036_00530) ispF 104404..104880 (+) 477 WP_003225745.1 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase -
  M036_RS00545 (M036_00535) gltX 104971..106422 (+) 1452 WP_004399675.1 glutamate--tRNA ligase -
  M036_RS00555 (M036_00545) cysE 106724..107377 (+) 654 WP_003225749.1 serine O-acetyltransferase -

Sequence

Protein


Download         Length: 360 a.a.        Molecular weight: 40734.29 Da        Isoelectric Point: 5.7343

>NTDB_id=99876 M036_RS00525 WP_003225736.1 101400..102482(+) (disA) [Bacillus subtilis TO-A]
MEKEKKGAKHELDLSSILQFVAPGTPLRAGMENVLRANTGGLIVVGYNDKVKEVVDGGFHINTAFSPAHLYELAKMDGAI
ILSDSGQKILYANTQLMPDATISSSETGMRHRTAERVAKQTGCLVIAISERRNVITLYQENMKYTLKDIGFILTKANQAI
QTLEKYKTILDKTINALNALEFEELVTFSDVLSVMHRYEMVLRIKNEINMYIKELGTEGHLIKLQVIELITDMEEEAALF
IKDYVKEKIKDPFVLLKELQDMSSYDLLDDSIVYKLLGYPASTNLDDYVLPRGYRLLNKIPRLPMPIVENVVEAFGVLPR
IIEASAEELDEVEGIGEVRAQKIKKGLKRLQEKHYLDRQL

Nucleotide


Download         Length: 1083 bp        

>NTDB_id=99876 M036_RS00525 WP_003225736.1 101400..102482(+) (disA) [Bacillus subtilis TO-A]
ATGGAAAAAGAGAAAAAAGGGGCGAAACACGAGTTAGACCTGTCATCTATATTGCAGTTTGTTGCTCCGGGTACACCGCT
CAGAGCGGGGATGGAAAACGTCTTGAGAGCAAATACAGGCGGTCTGATTGTTGTTGGATATAATGATAAAGTAAAAGAAG
TGGTGGACGGCGGCTTTCACATAAACACGGCTTTTTCTCCGGCGCATTTATATGAGCTGGCTAAAATGGATGGAGCGATC
ATTTTAAGTGATTCTGGTCAAAAGATCCTATACGCGAATACTCAGCTGATGCCGGATGCCACAATTTCTTCATCAGAAAC
AGGAATGCGGCACAGAACTGCCGAAAGAGTAGCTAAGCAAACTGGCTGTCTTGTAATCGCCATTTCTGAAAGAAGAAATG
TCATAACGTTATATCAGGAAAACATGAAGTATACACTAAAAGACATAGGATTTATTTTAACCAAGGCGAACCAAGCCATT
CAAACACTTGAAAAATATAAGACAATCCTCGATAAAACGATTAATGCACTGAACGCGTTAGAGTTTGAGGAACTTGTTAC
CTTCAGTGATGTCTTGTCTGTCATGCATCGTTATGAAATGGTACTGAGAATCAAAAACGAAATTAATATGTATATCAAAG
AGCTGGGGACAGAAGGGCATCTGATCAAACTGCAAGTCATTGAATTGATTACGGATATGGAAGAAGAGGCCGCTTTATTT
ATTAAGGACTATGTAAAAGAAAAGATTAAAGATCCGTTTGTTCTCTTGAAGGAGCTGCAGGATATGTCCAGTTATGATCT
GCTGGATGATTCCATTGTGTATAAGCTTCTCGGTTACCCTGCTTCTACTAATCTTGATGATTATGTATTGCCGAGAGGAT
ACAGGCTGTTAAATAAGATACCGCGTCTTCCGATGCCGATTGTTGAAAATGTTGTAGAAGCATTTGGAGTCCTGCCAAGG
ATTATTGAGGCGAGTGCAGAAGAATTAGATGAAGTAGAGGGAATCGGTGAAGTACGAGCCCAAAAAATCAAAAAAGGATT
AAAACGCCTGCAAGAGAAGCATTATTTAGACAGACAACTGTGA

Domains

Predicted by InterProScan.

DisA bacterial checkpoint controller nucleotide-binding (DAC)

(29-141)

DisA bacterial checkpoint controller linker region (DisA-linker)

(146-284)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P37573

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  disA Bacillus subtilis subsp. subtilis str. 168

100

100

1

Multiple sequence alignment