Detailed information NTG0998759

Bioinformatically predicted

Overview

• Name: cytR
• Type: Regulator
• Locus tag: EL118_RS22920
• Genome accession: NZ_LR134228
• Coordinates: 4727610..4728635 (+)
• Length: 341 a.a.
• NCBI ID: WP_000644904.1
• Uniprot ID: P0ACN8
• Organism: Escherichia coli strain NCTC9699
• Function: promote competence gene expression (predicted from homology) Competence regulation

Genomic Context

Location: 4722610..4733635

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL118_RS22910 (NCTC9699_04578)	rpmE	4724841..4725053 (-)	213	WP_000710769.1	50S ribosomal protein L31	-
EL118_RS22915 (NCTC9699_04579)	priA	4725256..4727454 (+)	2199	WP_001301269.1	primosomal protein N'	Machinery gene
EL118_RS22920 (NCTC9699_04580)	cytR	4727610..4728635 (+)	1026	WP_000644904.1	DNA-binding transcriptional regulator CytR	Regulator
EL118_RS22925 (NCTC9699_04581)	ftsN	4728727..4729686 (+)	960	WP_000068828.1	cell division protein FtsN	-
EL118_RS22930 (NCTC9699_04582)	hslV	4729779..4730309 (+)	531	WP_000208242.1	ATP-dependent protease subunit HslV	-
EL118_RS22935 (NCTC9699_04583)	hslU	4730319..4731650 (+)	1332	WP_001293341.1	HslU--HslV peptidase ATPase subunit	-
EL118_RS22940 (NCTC9699_04584)	menA	4731717..4732643 (+)	927	WP_000139496.1	1,4-dihydroxy-2-naphthoate polyprenyltransferase	-
EL118_RS22945 (NCTC9699_04585)	rraA	4732736..4733221 (+)	486	WP_000872908.1	ribonuclease E activity regulator RraA	-
EL118_RS22950 (NCTC9699_04586)	zapB	4733306..4733551 (-)	246	WP_001296623.1	septal ring assembly protein ZapB	-

Sequence

Protein

• Length: 341 a.a.
• Molecular weight: 37819.78 Da
• Isoelectric Point: 6.3842

>NTDB_id=998759 EL118_RS22920 WP_000644904.1 4727610..4728635(+) (cytR) [Escherichia coli strain NCTC9699]
MKAKKQETAATMKDVALKAKVSTATVSRALMNPDKVSQATRNRVEKAAREVGYLPQPMGRNVKRNESRTILVIVPDICDP
FFSEIIRGIEVTAANHGYLVLIGDCAHQNQQEKTFIDLIITKQIDGMLLLGSRLPFDASIEEQRNLPPMVMANEFAPELE
LPTVHIDNLTAAFDAVNYLYEQGHKRIGCIAGPEEMPLCHYRLQGYVQALRRCGIMVDPQYIARGDFTFEAGSKAMQQLL
DLPQPPTAVFCHSDVMALGALSQAKRQGLKVPEDLSIIGFDNIDLTQFCDPPLTTIAQPRYEIGREAMLLLLDQMQGQHV
GSGSRLMDCELIIRGSTRALP

Nucleotide

• Length: 1026 bp

>NTDB_id=998759 EL118_RS22920 WP_000644904.1 4727610..4728635(+) (cytR) [Escherichia coli strain NCTC9699]
GTGAAAGCGAAGAAGCAGGAAACTGCCGCGACCATGAAAGACGTTGCCCTCAAGGCAAAAGTCTCTACAGCGACCGTCTC
CCGAGCATTAATGAATCCCGATAAAGTCTCCCAGGCCACCCGTAATCGGGTTGAAAAAGCGGCCCGGGAAGTGGGTTATT
TACCGCAGCCTATGGGGCGCAACGTCAAGCGTAATGAATCCCGCACCATTCTGGTGATTGTCCCGGATATCTGCGATCCC
TTCTTTAGCGAAATTATTCGCGGTATCGAAGTTACGGCGGCAAATCACGGATATCTGGTGCTGATTGGCGACTGTGCGCA
TCAAAATCAGCAGGAAAAAACCTTTATCGATTTGATCATCACCAAGCAAATTGATGGCATGTTGTTGCTGGGTTCAAGGC
TGCCGTTTGATGCCAGCATTGAGGAACAGCGTAATCTGCCGCCGATGGTGATGGCGAACGAATTTGCACCGGAGCTGGAG
CTGCCTACAGTTCATATCGACAATCTGACCGCCGCATTTGATGCAGTAAATTATTTATATGAGCAAGGGCATAAACGGAT
TGGCTGTATAGCCGGTCCCGAAGAGATGCCGCTGTGTCACTACCGCCTGCAAGGCTATGTTCAGGCGCTGCGTCGCTGCG
GCATTATGGTTGATCCGCAATACATCGCCCGTGGCGACTTCACCTTCGAAGCCGGAAGCAAAGCGATGCAGCAGCTGCTT
GATCTTCCACAACCGCCTACTGCTGTCTTCTGCCATAGCGATGTGATGGCGCTCGGCGCACTTTCTCAGGCAAAACGCCA
GGGGCTGAAAGTCCCGGAAGACCTTTCCATAATCGGTTTTGATAACATCGACCTGACGCAATTTTGTGATCCGCCGCTGA
CAACCATCGCGCAGCCGCGTTACGAAATCGGTCGGGAAGCTATGCTGTTATTGCTTGATCAAATGCAGGGGCAACACGTT
GGCAGTGGCTCTCGTTTAATGGACTGCGAACTTATCATCCGGGGATCAACACGCGCGTTACCTTAA

Domains

Predicted by InterProScan.

• Bacterial regulatory proteins, lacI family (LacI) (11-56)

• Periplasmic binding protein-like domain (Peripla_BP_3) (176-337)

3D structure

• AlphaFold DB: P0ACN8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
cytR	Vibrio parahaemolyticus RIMD 2210633	64.179	98.24	0.63
cytR	Vibrio cholerae C6706	65.443	95.894	0.628