Detailed information NTG0998205

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: EL020_RS02630
• Genome accession: NZ_LR134203
• Coordinates: 523287..525854 (-)
• Length: 855 a.a.
• NCBI ID: WP_111699139.1
• Uniprot ID: -
• Organism: Streptococcus lutetiensis strain NCTC11436
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 518287..530854

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL020_RS02610 (NCTC11436_00542)	-	518669..519598 (-)	930	WP_228380499.1	MFS transporter	-
EL020_RS09785 (NCTC11436_00543)	-	519624..519851 (-)	228	WP_231997011.1	MFS transporter	-
EL020_RS02615 (NCTC11436_00544)	-	520052..520603 (-)	552	WP_043895144.1	DNA-3-methyladenine glycosylase I	-
EL020_RS02620 (NCTC11436_00545)	ruvA	520633..521226 (-)	594	WP_020917597.1	Holliday junction branch migration protein RuvA	Machinery gene
EL020_RS02625 (NCTC11436_00546)	hexB	521227..523167 (-)	1941	WP_020917598.1	DNA mismatch repair endonuclease MutL	Machinery gene
EL020_RS02630 (NCTC11436_00547)	hexA	523287..525854 (-)	2568	WP_111699139.1	DNA mismatch repair protein MutS	Machinery gene
EL020_RS02635 (NCTC11436_00548)	-	525841..526194 (-)	354	WP_020917600.1	YlbF family regulator	-
EL020_RS02640 (NCTC11436_00549)	argR	526191..526628 (-)	438	WP_020917601.1	arginine repressor	-
EL020_RS02645 (NCTC11436_00550)	argS	526818..528509 (+)	1692	WP_111699141.1	arginine--tRNA ligase	-
EL020_RS02650 (NCTC11436_00551)	-	528557..529975 (-)	1419	WP_126402385.1	prolyl oligopeptidase family serine peptidase	-

Sequence

Protein

• Length: 855 a.a.
• Molecular weight: 95924.15 Da
• Isoelectric Point: 4.9508

>NTDB_id=998205 EL020_RS02630 WP_111699139.1 523287..525854(-) (hexA) [Streptococcus lutetiensis strain NCTC11436]
MAKDKISPGMQQYLDVKKDYPEAFLLFRMGDFYELFYDDAVKAAQILEISLTSRNKNADNPIPMAGVPYHSAQQYIDVLV
EMGYKVAIAEQMEDPKQAVGVVKREVIQVITPGTAVDSSKPDNANNFLVAIDSDGKTFGLAYMDVSTGEFYATSLSDFTS
LKSEILNLKAREIVVGYDLSEDEQHSLVKQLNLLLSFEQERYEDVHLIDPNLTALEISAAEKLLQYVHTTQKRELSHLQK
LVHYEIKDYLQMSYTTKSSLDLLENARTSKKHGSLYWLLDETKTAMGMRLLRNWIDRPLVNQEQIEERQNIIQVFLDNFF
ERSDLTDSLKGVYDIERLASRVSFGKANPKDLLQLGHTLGQVPTIKAILESFDSPYLDKLVNSIDTLPELKSLISSAIDS
DAQAVITEGSIIRTGFDETLDKYRKVMREGTSWIAEIEAKERAASGITNLKIDYNKKDGYYFHVTNSNLSLVPDYFFRKA
TLKNSERFGTAELAKIEGEMLEAHEQSASLEYDIFMRVRAQVERYISRLQDLAKAISTVDVLQSLAVVAENNHYVRPTFN
NNHEIKIDKGRHAVVEKVMGTQEYIPNTITFGRNINIQLITGPNMSGKSTYMRQLALTVIMAQMGSYVAAESVSLPVFDA
IFTRIGAADDLISGQSTFMVEMMEANQAIKRASEKSLILFDELGRGTATYDGMALAQSIIEYIHDHIGAKTMFATHYHEL
TPLSTTLTHLVNVHVATLERNGDVTFLHKIAEGPADKSYGIHVAKIAGLPEDLLQRAGSILTNLESGAAQLHLTAETEEK
TQVKTEAAEPVAEQLSLFADDSSNQEVIEALKKVDLMNLTPMQAMNVIYELKNML

Nucleotide

• Length: 2568 bp

>NTDB_id=998205 EL020_RS02630 WP_111699139.1 523287..525854(-) (hexA) [Streptococcus lutetiensis strain NCTC11436]
ATGGCAAAAGATAAAATTTCTCCAGGCATGCAACAGTATTTGGATGTCAAAAAAGACTATCCAGAGGCTTTTTTACTTTT
CCGCATGGGAGACTTTTACGAACTATTTTATGATGACGCCGTTAAGGCGGCACAGATTTTAGAGATTAGTTTAACTAGTC
GTAATAAAAATGCTGACAATCCTATTCCGATGGCTGGTGTTCCTTATCATTCAGCCCAACAATACATTGATGTCTTGGTT
GAGATGGGGTATAAGGTTGCCATTGCTGAGCAGATGGAAGATCCGAAGCAGGCAGTGGGTGTGGTTAAGCGTGAAGTCAT
TCAGGTTATTACACCAGGGACAGCGGTTGATTCTTCTAAGCCAGATAATGCTAATAATTTCTTGGTAGCCATCGATTCAG
ATGGTAAAACTTTTGGTTTGGCATACATGGATGTGTCAACGGGTGAGTTTTACGCGACAAGTTTGTCTGATTTTACAAGC
CTAAAAAGTGAGATTTTAAATCTCAAGGCTCGTGAAATCGTGGTTGGTTATGACCTTTCTGAAGATGAGCAACACAGCTT
GGTTAAACAACTCAATCTCTTATTATCGTTTGAGCAAGAGCGCTATGAAGATGTGCATTTGATTGACCCTAATTTAACAG
CGTTAGAGATTTCTGCTGCTGAAAAATTACTTCAATACGTTCACACAACACAAAAACGTGAACTTAGTCACTTGCAAAAG
CTTGTTCACTATGAAATCAAAGACTATCTTCAAATGTCTTATACGACAAAATCAAGTCTTGATTTGCTAGAAAATGCCCG
TACTAGCAAGAAACACGGTAGTCTTTATTGGTTGCTTGATGAGACTAAAACTGCCATGGGGATGCGTTTGTTGCGTAACT
GGATTGATCGTCCATTGGTTAACCAAGAACAAATTGAAGAACGTCAAAATATTATTCAAGTTTTCTTAGACAACTTCTTT
GAACGTAGTGATTTGACGGACAGTCTAAAAGGTGTCTATGATATTGAACGTTTGGCTAGTCGCGTGTCATTTGGAAAAGC
CAATCCAAAAGATTTGCTTCAACTTGGTCACACTTTGGGGCAAGTGCCAACGATTAAAGCTATCTTGGAGTCTTTTGATA
GTCCGTACCTTGACAAGCTTGTCAACAGCATTGACACTTTACCAGAGCTAAAGTCATTGATTAGCTCTGCTATTGATTCA
GATGCTCAAGCGGTGATTACGGAAGGAAGTATTATCAGAACTGGTTTTGATGAGACTTTGGACAAATACCGTAAAGTCAT
GCGCGAAGGGACAAGCTGGATTGCTGAGATTGAAGCTAAAGAACGTGCGGCAAGTGGCATTACCAATCTAAAAATTGATT
ACAATAAAAAAGATGGCTATTATTTCCATGTCACAAATTCTAACCTTTCTTTGGTGCCAGATTACTTCTTCCGTAAAGCA
ACTTTGAAGAATTCAGAGCGTTTTGGTACAGCAGAATTGGCTAAAATTGAAGGTGAAATGCTAGAAGCGCATGAGCAATC
AGCGAGTCTGGAATACGATATTTTCATGCGTGTTCGCGCACAGGTGGAACGTTATATTTCACGTCTGCAAGATTTGGCAA
AAGCTATTTCTACAGTCGATGTTCTGCAAAGTTTGGCAGTGGTTGCGGAAAATAATCATTACGTGCGTCCAACTTTCAAC
AATAATCATGAAATTAAGATTGATAAAGGTCGCCATGCAGTTGTTGAAAAAGTCATGGGCACGCAAGAGTATATTCCAAA
TACCATTACATTTGGCAGAAATATCAATATTCAGCTGATTACTGGTCCAAATATGAGTGGTAAATCAACTTATATGCGTC
AGTTAGCTTTGACGGTTATCATGGCACAGATGGGGTCATACGTTGCTGCTGAGAGTGTTAGTCTTCCAGTTTTTGATGCG
ATTTTCACACGTATCGGTGCGGCGGATGATTTGATTTCAGGTCAGTCAACCTTCATGGTGGAAATGATGGAAGCCAACCA
AGCCATTAAACGTGCTAGTGAAAAATCTTTGATTCTCTTTGATGAATTGGGACGCGGGACAGCGACTTATGATGGAATGG
CTTTAGCACAATCTATCATTGAGTATATCCATGATCACATTGGTGCTAAGACCATGTTTGCGACTCACTATCATGAATTG
ACACCTCTGTCAACTACCTTGACACATCTTGTAAACGTCCATGTTGCAACGCTTGAACGTAATGGTGATGTGACTTTTCT
TCATAAAATCGCAGAAGGACCAGCTGACAAATCTTATGGTATTCACGTTGCGAAAATTGCAGGTTTGCCAGAAGATTTGT
TGCAACGAGCAGGTAGTATTTTAACCAATCTCGAATCAGGTGCTGCGCAGCTTCATTTGACAGCAGAAACTGAAGAGAAA
ACTCAAGTGAAGACAGAAGCGGCAGAACCTGTTGCAGAGCAGCTTAGCTTATTTGCAGATGACTCAAGTAACCAAGAAGT
GATTGAAGCTCTTAAAAAAGTGGACTTGATGAATCTAACACCAATGCAAGCCATGAATGTCATTTATGAATTGAAAAACA
TGTTATAA

Domains

Predicted by InterProScan.

• MutS domain I (MutS_I) (8-118)

• MutS domain V (MutS_V) (599-785)

• MutS family domain IV (MutS_IV) (415-505)

• MutS domain II (MutS_II) (126-239)

• MutS domain III (MutS_III) (256-546)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	71.813	100	0.718
mutS	Pseudomonas stutzeri strain ATCC 17587	37.113	100	0.379