Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   AAH949_RS03470 Genome accession   NZ_CP155620
Coordinates   677700..679493 (-) Length   597 a.a.
NCBI ID   WP_348518991.1    Uniprot ID   A0AAU7E7C7
Organism   Campylobacter sp. CCS1377     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 672700..684493
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AAH949_RS03445 (AAH949_03445) dnaJ 672712..673827 (-) 1116 WP_348518989.1 molecular chaperone DnaJ -
  AAH949_RS03450 (AAH949_03450) - 673978..674655 (+) 678 WP_134239227.1 response regulator transcription factor -
  AAH949_RS03455 (AAH949_03455) - 674652..675923 (+) 1272 WP_348518990.1 ArsS family sensor histidine kinase -
  AAH949_RS03460 (AAH949_03460) recR 675930..676505 (+) 576 WP_134239224.1 recombination mediator RecR -
  AAH949_RS03465 (AAH949_03465) - 676486..677703 (-) 1218 WP_134239222.1 hypothetical protein -
  AAH949_RS03470 (AAH949_03470) uvrC 677700..679493 (-) 1794 WP_348518991.1 excinuclease ABC subunit UvrC Machinery gene
  AAH949_RS03475 (AAH949_03475) - 679475..679951 (-) 477 WP_134239219.1 hypothetical protein -
  AAH949_RS03480 (AAH949_03480) guaA 680100..681635 (+) 1536 WP_134239217.1 glutamine-hydrolyzing GMP synthase -
  AAH949_RS03485 (AAH949_03485) - 681742..683160 (+) 1419 WP_348518992.1 hypothetical protein -

Sequence

Protein


Download         Length: 597 a.a.        Molecular weight: 69364.00 Da        Isoelectric Point: 9.5554

>NTDB_id=998064 AAH949_RS03470 WP_348518991.1 677700..679493(-) (uvrC) [Campylobacter sp. CCS1377]
MLEQELKNLPQNSGIYQYFDAQGKLLYVGKAKNLKNRIRSYFIFSPRLEANPRNSLRIQKMISEAKHLEFINTDSEADAL
ILENSLIKQLHPKYNILLRDDKTYPYIYIDFNEDFPRFEITRKIIKKSKIKYFGPFFKGAKELLDALYLNFTLKQKKSCK
QACIFHQIKRCHAPCENKISKEEYKQIINQATQALLNPSILIKNLEKKMLDYAEHENYEEAAKIRDQIQTIKDLDTKIHI
DIAKLENFDVFAVAFESNTLASLHFVIQEGKVIGTNHKTIALKDANSFDKNQIYQQLILEHFSADSPLSSEQIYVYEEFE
DLKLLQDLLTQRFGKKISIKSPKIGEKRKICDLAYKNACMNIKLFCKNSNYALLQELKDYFELENFPNSIEVFDNSHMQG
RACVAGMISYKFENFDKKSYRHFHLHTNNDFEQMQETLTRRAKDFDKISPPDLWLIDGGKVLLDLAREIIQSSGANVDVL
AISKEKIDAKAHRAKGNAKDKIHSFKGEFKLSPMDKKLQFLQKLRDEAHRFAISFHQNVKKKQDLQSSKLKNLGISEGNI
QKLLNFFGNFDTIHKASLEELSSIVRLDIAKKIKGIQ

Nucleotide


Download         Length: 1794 bp        

>NTDB_id=998064 AAH949_RS03470 WP_348518991.1 677700..679493(-) (uvrC) [Campylobacter sp. CCS1377]
ATGCTCGAACAAGAACTAAAAAATTTACCTCAAAATAGCGGAATTTATCAGTATTTTGACGCACAAGGAAAGCTCCTTTA
TGTAGGAAAGGCAAAAAATTTAAAAAATCGCATACGAAGTTATTTTATTTTTTCTCCAAGACTCGAAGCCAATCCTAGAA
ATTCACTCAGAATTCAAAAAATGATCAGCGAGGCAAAACACTTAGAATTTATCAATACAGATTCTGAAGCTGATGCTTTG
ATTTTAGAAAATTCCCTTATTAAACAACTGCATCCAAAATACAATATTTTGCTAAGAGATGATAAAACTTATCCTTATAT
TTACATTGATTTTAATGAAGATTTTCCGCGTTTTGAAATCACTAGAAAAATCATTAAAAAATCAAAAATTAAATATTTTG
GCCCATTTTTTAAAGGTGCAAAAGAACTCTTAGATGCACTATATCTTAATTTTACCCTAAAGCAAAAAAAGAGTTGTAAG
CAAGCTTGTATTTTTCATCAAATTAAGCGTTGCCATGCCCCTTGTGAAAATAAAATTTCAAAAGAAGAATATAAACAAAT
CATCAATCAAGCCACGCAAGCTTTGTTAAATCCTAGTATTTTAATCAAAAATTTAGAAAAAAAGATGTTGGATTACGCCG
AACATGAAAATTACGAAGAAGCTGCAAAAATAAGGGATCAAATTCAAACAATAAAAGATTTAGATACGAAAATCCATATC
GATATTGCTAAACTTGAAAATTTCGATGTTTTTGCAGTCGCTTTTGAGTCAAATACCCTTGCAAGCTTGCACTTTGTTAT
CCAAGAAGGTAAAGTAATAGGCACAAATCACAAAACAATAGCTTTAAAAGATGCCAATTCTTTCGATAAAAACCAAATTT
ATCAACAACTCATCTTAGAACATTTTAGCGCCGATTCCCCTTTAAGCTCTGAGCAAATTTATGTTTATGAGGAATTTGAA
GATTTAAAACTTTTACAAGATTTATTGACACAAAGGTTTGGCAAAAAAATCAGCATCAAAAGCCCAAAGATAGGAGAAAA
AAGAAAAATTTGCGATCTAGCGTATAAAAATGCTTGTATGAACATTAAGCTTTTTTGTAAAAATTCGAATTATGCTTTAT
TGCAGGAATTAAAAGATTATTTTGAGTTAGAAAATTTTCCAAATTCTATAGAGGTTTTTGATAATTCTCATATGCAAGGA
AGAGCTTGCGTGGCTGGAATGATAAGTTACAAATTTGAAAATTTCGATAAAAAATCTTATAGACATTTCCATCTTCATAC
TAACAATGATTTTGAACAAATGCAAGAGACATTAACAAGACGCGCCAAAGATTTTGATAAAATATCACCTCCTGATTTAT
GGCTTATTGATGGCGGAAAGGTTTTGCTTGATTTGGCTAGAGAAATCATACAAAGCAGTGGGGCAAATGTTGATGTTTTA
GCAATTTCAAAAGAAAAAATTGACGCAAAAGCTCACCGCGCTAAAGGCAACGCTAAAGATAAAATTCACTCTTTTAAAGG
CGAATTTAAACTTTCGCCTATGGATAAAAAATTACAATTTTTACAAAAATTACGCGACGAAGCCCATCGTTTTGCAATCA
GTTTTCATCAAAATGTAAAGAAAAAGCAAGATTTACAAAGCTCAAAACTAAAAAATCTTGGCATCAGTGAAGGAAATATT
CAAAAATTATTAAATTTTTTTGGTAATTTTGATACAATTCATAAAGCGAGCTTAGAAGAACTTTCAAGCATAGTAAGACT
TGATATTGCTAAAAAAATAAAGGGAATTCAATGA

Domains

Predicted by InterproScan.

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(379-533)

GIY-YIG catalytic domain (GIY-YIG)

(13-95)

UvrB/uvrC motif (UVR)

(201-233)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

48.567

99.33

0.482

Multiple sequence alignment