Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexA   Type   Machinery gene
Locus tag   ELZ51_RS10665 Genome accession   NZ_LR134094
Coordinates   2126003..2128558 (-) Length   851 a.a.
NCBI ID   WP_126427500.1    Uniprot ID   -
Organism   Streptococcus dysgalactiae subsp. dysgalactiae strain NCTC4669     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 2121003..2133558
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ELZ51_RS10660 (NCTC4669_02247) - 2122082..2125312 (+) 3231 WP_126427498.1 serum opacification factor -
  ELZ51_RS10665 (NCTC4669_02248) hexA 2126003..2128558 (-) 2556 WP_126427500.1 DNA mismatch repair protein MutS Machinery gene
  ELZ51_RS10670 (NCTC4669_02249) - 2128545..2128898 (-) 354 WP_126427502.1 YlbF family regulator -
  ELZ51_RS10675 (NCTC4669_02250) argR 2128895..2129332 (-) 438 WP_003053124.1 arginine repressor -
  ELZ51_RS10680 (NCTC4669_02251) argS 2129620..2131311 (+) 1692 WP_126427504.1 arginine--tRNA ligase -
  ELZ51_RS10685 (NCTC4669_02252) - 2131381..2132778 (-) 1398 WP_126427506.1 ATP-binding cassette domain-containing protein -

Sequence

Protein


Download         Length: 851 a.a.        Molecular weight: 95858.47 Da        Isoelectric Point: 4.9473

>NTDB_id=997790 ELZ51_RS10665 WP_126427500.1 2126003..2128558(-) (hexA) [Streptococcus dysgalactiae subsp. dysgalactiae strain NCTC4669]
MAKANISPGMQQYLDIKKDYPDAFLLFRMGDFYELFYDDAVKAAQLLEIGLTSRNKNAENPIPMAGVPHHSAQQYIDVLI
ELGYKVAIAEQMEDPKQAVGVVKREVVQVITPGTVVDSAKPDSANNFLVAVDFDGFRYGLAYMDVSTGEFCVTDLADFTS
VRSEIQNLKAKEVLLGFDLSEEEQMILVKQMNLLLSYEETVYEDKSLIDGQLTTVELTAAGKLLQYVHKTQMRELSHLQA
LVHYEIKDYLQMSYATKSSLDLVENARTNKKHGSLYWLLDETKTAMGMRLLRSWIDRPLVSKEAILERQEIIQVFLNAFI
ERTDLSNSLKGVYDIERLSSRVSFGKANPKDLLQLGHTLAQVPYIKAILESFSSPYIDKLVNDIDSLPELEYLIRTAIDP
DAPATISEGSIIRNGFDERLDHYRKVMREGTGWIADIEAKERQASGINNLKIDYNKKDGYYFHVTNSNLSLVPEHFFRKA
TLKNSERYGTAELAKIEGQMLEAREESASLEYDIFMCIRTQVETYINRLQKLAKTLATIDVLQSLAVVAETNHYIRPQFN
DNHVITIQEGRHAVVEKVMGVKEYIPNSISFDQETSIQLITGPNMSGKSTYMRQLALTVIMAQMGSFVAADYVNLPLFDA
IFTRIGAADDLISGQSTFMVEMMEANQAIKRASENSLILFDELGRGTATYDGMALAQAIIEHIHDRIGAKTMFATHYHEL
TELSTKLTRLINVHVETLEKGGDVTFLHKIAQGPADKSYGIHVAKIAGLPESLLNRADTVLTRFEAQSPSTDLISDSLRV
EQTNIAHKEQLSLFADEDRSQEIIRTLETIDVMNMTPMQAMTALYELKNLL

Nucleotide


Download         Length: 2556 bp        

>NTDB_id=997790 ELZ51_RS10665 WP_126427500.1 2126003..2128558(-) (hexA) [Streptococcus dysgalactiae subsp. dysgalactiae strain NCTC4669]
ATGGCAAAAGCTAACATTTCTCCTGGGATGCAACAGTATCTGGACATCAAAAAAGATTATCCAGATGCTTTTTTGCTTTT
TAGGATGGGTGACTTTTATGAATTATTTTATGATGATGCTGTCAAGGCAGCGCAACTTTTAGAGATTGGTTTGACCAGTC
GTAACAAGAATGCGGAAAATCCAATTCCCATGGCAGGAGTGCCACATCATTCTGCCCAGCAATACATTGATGTGTTAATT
GAGTTGGGTTACAAGGTAGCTATTGCAGAACAGATGGAGGACCCCAAACAAGCTGTTGGAGTGGTGAAGCGTGAAGTTGT
TCAAGTCATAACTCCTGGAACGGTTGTGGATTCAGCTAAGCCAGATAGCGCCAATAACTTTTTGGTAGCTGTTGACTTTG
ATGGTTTTCGTTATGGATTGGCTTATATGGATGTGTCCACAGGTGAATTTTGCGTGACAGATTTAGCGGACTTTACGAGT
GTTCGTAGCGAAATCCAAAACCTCAAGGCAAAAGAAGTCTTACTAGGTTTTGATTTATCTGAAGAAGAACAGATGATTTT
GGTCAAGCAGATGAATTTGCTGCTTTCTTATGAGGAAACGGTCTATGAAGATAAATCTTTAATTGACGGCCAATTGACAA
CGGTAGAATTAACAGCGGCAGGAAAACTCTTGCAATATGTTCACAAAACACAAATGCGAGAACTTAGCCACTTGCAAGCC
TTGGTTCACTATGAAATCAAGGATTATTTGCAGATGTCGTATGCCACTAAGTCAAGTTTAGATTTGGTAGAGAATGCTAG
AACGAATAAAAAACATGGGAGTCTCTATTGGCTTTTAGATGAAACCAAGACAGCTATGGGGATGAGGCTTTTGCGCTCAT
GGATTGATCGACCTTTGGTTTCTAAAGAAGCGATTTTAGAGCGTCAAGAAATTATTCAAGTTTTTCTGAATGCTTTTATT
GAGCGAACAGATTTAAGCAATAGCTTAAAAGGTGTTTACGATATCGAACGCTTATCTAGTCGCGTGTCTTTTGGAAAGGC
AAATCCGAAAGATTTACTTCAATTGGGGCATACCTTAGCCCAAGTACCCTATATCAAAGCTATTTTAGAGTCTTTTAGCA
GCCCTTATATTGACAAACTTGTCAATGATATTGACAGTTTACCTGAGTTGGAATACTTGATTAGAACAGCCATTGATCCA
GATGCACCAGCAACTATTAGTGAGGGAAGTATTATCCGCAATGGTTTTGATGAGCGCTTGGACCATTATCGTAAAGTAAT
GCGAGAGGGGACAGGCTGGATTGCGGATATTGAGGCCAAAGAGCGTCAAGCCAGCGGCATTAATAACCTAAAAATTGATT
ACAATAAAAAAGATGGTTATTATTTTCACGTTACGAATTCAAATCTTAGCTTAGTACCTGAGCATTTTTTCAGAAAGGCA
ACTTTAAAAAATTCCGAACGTTATGGTACGGCAGAATTGGCTAAGATTGAAGGTCAGATGTTAGAGGCTAGGGAAGAATC
AGCTAGTTTAGAATACGATATTTTTATGTGTATTCGAACTCAAGTTGAAACCTATATTAATCGTTTGCAGAAGCTTGCCA
AAACCTTGGCAACGATTGATGTCTTGCAAAGTTTAGCAGTTGTTGCCGAAACCAATCATTATATCCGGCCGCAGTTCAAT
GATAATCATGTGATTACGATTCAAGAAGGTCGTCACGCGGTTGTTGAAAAGGTTATGGGAGTGAAGGAATACATTCCAAA
TAGTATCTCTTTTGACCAAGAGACAAGCATTCAATTGATTACAGGTCCAAATATGAGTGGTAAGTCGACTTATATGAGAC
AACTAGCCTTAACGGTTATCATGGCCCAGATGGGCTCGTTTGTGGCTGCTGATTATGTGAATTTGCCTTTATTTGATGCT
ATTTTCACGCGAATTGGCGCTGCTGATGATTTGATTTCCGGTCAATCGACTTTCATGGTAGAGATGATGGAAGCTAATCA
AGCGATCAAACGTGCTAGTGAAAATTCTCTCATTTTATTTGATGAATTGGGACGAGGCACAGCGACCTATGATGGTATGG
CATTGGCTCAGGCAATTATCGAACACATTCATGATAGGATCGGTGCAAAAACCATGTTTGCAACGCATTACCACGAATTG
ACAGAGTTGTCAACGAAGTTGACAAGATTGATCAATGTCCATGTGGAAACACTTGAAAAAGGTGGTGATGTTACCTTTCT
TCATAAGATTGCCCAAGGACCTGCGGATAAATCTTATGGTATTCATGTAGCTAAAATAGCAGGTCTGCCAGAGTCTCTAT
TAAATAGAGCAGACACAGTTCTTACACGATTTGAAGCACAGTCACCATCAACTGACCTCATATCGGATTCTCTAAGAGTT
GAGCAAACTAATATAGCTCATAAGGAACAATTATCACTTTTTGCTGATGAGGATAGATCTCAAGAAATTATTCGAACTTT
AGAAACTATTGATGTCATGAACATGACTCCAATGCAAGCTATGACGGCGTTATATGAATTGAAAAACTTATTATAG

Domains

Predicted by InterProScan.

MutS domain I (MutS_I)

(8-118)

MutS domain II (MutS_II)

(126-239)

MutS family domain IV (MutS_IV)

(415-506)

MutS domain V (MutS_V)

(599-784)

MutS domain III (MutS_III)

(256-546)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexA Streptococcus pneumoniae R6

70.809

100

0.71
  mutS Pseudomonas stutzeri strain ATCC 17587

37.602

100

0.38