Detailed information NTG0997689

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: ELZ56_RS13655
• Genome accession: NZ_LR134093
• Coordinates: 2649289..2651394 (+)
• Length: 701 a.a.
• NCBI ID: WP_126523611.1
• Uniprot ID: -
• Organism: Staphylococcus aureus strain NCTC11965
• Function: repress competence development (at the early growth phase) (predicted from homology) Competence regulation

Genomic Context

Location: 2644289..2656394

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ELZ56_RS13630 (NCTC11965_02575)	-	2644356..2644574 (+)	219	WP_000011687.1	sterile alpha motif-like domain-containing protein	-
ELZ56_RS13635 (NCTC11965_02576)	-	2644962..2645393 (+)	432	WP_000875613.1	CHAP domain-containing protein	-
ELZ56_RS13640 (NCTC11965_02577)	-	2645533..2646813 (-)	1281	WP_001191011.1	hydroxymethylglutaryl-CoA reductase, degradative	-
ELZ56_RS13645 (NCTC11965_02578)	-	2647068..2648234 (+)	1167	WP_000172190.1	hydroxymethylglutaryl-CoA synthase	-
ELZ56_RS13650 (NCTC11965_02579)	-	2648405..2648926 (-)	522	WP_000262597.1	methylated-DNA--[protein]-cysteine S-methyltransferase	-
ELZ56_RS13655 (NCTC11965_02580)	clpE	2649289..2651394 (+)	2106	WP_126523611.1	ATP-dependent Clp protease ATP-binding subunit ClpL	Regulator
ELZ56_RS13660 (NCTC11965_02581)	-	2651464..2651634 (-)	171	WP_000111116.1	FeoB-associated Cys-rich membrane protein	-
ELZ56_RS13665 (NCTC11965_02582)	feoB	2651647..2653641 (-)	1995	WP_000432892.1	ferrous iron transport protein B	-
ELZ56_RS13670 (NCTC11965_02583)	-	2653653..2653880 (-)	228	WP_000932073.1	FeoA family protein	-

Sequence

Protein

• Length: 701 a.a.
• Molecular weight: 78013.61 Da
• Isoelectric Point: 4.7492

>NTDB_id=997689 ELZ56_RS13655 WP_126523611.1 2649289..2651394(+) (clpE) [Staphylococcus aureus strain NCTC11965]
MNNNFFNSDFDSILRRMMQDMQNSNQTSNKKYYINGKEVSPEELAQFTQQGGNHSAEQSAQAFQQAALRQQGQQSGNGNY
LEQIGRNLTQEARDGLLDPVIGRDKEIQETAEVLSRRTKNNPILVGEAGVGKTAIVEGLAQAIVEGNVPAAIKDKEIISI
DISSLEAGTQYRGAFEENIQKLVEGVKSSQNAVLFFDEIHQIIGSGATGSDSGSKGLSDILKPALSRGEISIIGATTQDE
YRNNIMKDAALTRRFNEVLVNEPSAKDTVEILKGIREKFETHHQVKLPDDVLKACVDLSIQYIPQRLLPDKAIDVLDITA
AHLSAQSPAIDKVTTEKRISELEHDKRKAVSAEEYKKADDIQKEIKSLQDKLENSNGEHTAVATVHDISDTIQRLTGIPV
SQMDANDIERLKNISSRLRSKIIGQDKAVEMVSRAIRRNRAGFDDGNRPIGSFLFVGPTGVSKTELAKQLAIDLFGNKEA
LIRLDMSEYSDTTAVSKMIGTTAGYVGYDDNSNTLTEKVRRNPYSVILFDEIEKANPQILTLLLQVMDDGNLTDGQGNVI
NFKNTIIICTSNAGFGNGNDTEEKDIMHEMKKFFRPEFLNRFNGIVEFLHLDKDALQDIVNLLLDDVQVTLDKKGITMDV
SQDAKDWLIEEGYDEELGARPLRRIVEQQVRDKITDYYLDHTDVKHVDIDVEDNELVVKGK

Nucleotide

• Length: 2106 bp

>NTDB_id=997689 ELZ56_RS13655 WP_126523611.1 2649289..2651394(+) (clpE) [Staphylococcus aureus strain NCTC11965]
ATGAATAACAATTTTTTCAATAGTGACTTCGATTCTATTTTACGAAGAATGATGCAAGACATGCAAAACTCAAATCAGAC
TAGTAACAAGAAATACTATATTAATGGTAAAGAAGTTTCACCGGAAGAATTAGCACAATTTACGCAACAAGGTGGTAATC
ATTCTGCCGAACAAAGTGCGCAAGCTTTTCAACAAGCAGCACTAAGACAACAAGGTCAACAAAGTGGCAATGGCAATTAT
TTAGAACAAATTGGTCGTAACTTAACGCAAGAGGCTCGTGACGGATTATTAGATCCAGTCATCGGTCGTGATAAAGAAAT
CCAAGAAACTGCAGAAGTCTTAAGTAGACGCACTAAAAACAATCCTATCCTAGTCGGAGAAGCTGGAGTTGGTAAAACTG
CGATTGTCGAAGGTTTAGCGCAAGCAATCGTTGAAGGGAACGTACCTGCAGCAATCAAAGATAAAGAAATTATATCTATA
GATATTTCATCGCTTGAAGCTGGAACGCAATATCGTGGCGCCTTTGAAGAAAACATCCAAAAGTTAGTTGAAGGCGTTAA
GTCATCACAAAATGCTGTGCTCTTCTTTGACGAAATTCACCAAATCATCGGTTCCGGTGCCACAGGAAGTGATTCAGGTA
GCAAAGGGTTATCTGATATTTTAAAACCAGCATTAAGTCGTGGTGAAATTTCAATTATAGGTGCAACGACTCAAGATGAA
TATCGCAATAATATCATGAAAGACGCTGCATTAACACGTCGTTTTAACGAGGTACTGGTTAACGAACCAAGCGCAAAAGA
TACGGTTGAAATTTTAAAAGGAATTCGCGAAAAATTTGAAACACACCATCAAGTCAAATTACCTGATGACGTATTAAAGG
CATGTGTAGACTTATCCATTCAATATATTCCACAACGCCTATTACCTGACAAAGCAATCGATGTATTAGATATTACAGCT
GCACATTTATCTGCACAAAGTCCTGCTATTGATAAAGTCACGACTGAAAAACGTATTTCTGAATTGGAACATGATAAGCG
TAAAGCTGTAAGTGCTGAAGAATATAAAAAAGCAGATGACATTCAAAAAGAAATTAAATCTCTACAAGATAAATTAGAAA
ACAGTAATGGTGAACATACTGCAGTAGCAACGGTGCATGATATTTCTGATACCATTCAACGATTAACTGGTATTCCTGTA
TCTCAAATGGATGCCAATGACATTGAACGTTTAAAAAATATTTCTAGTCGTTTAAGAAGTAAAATCATCGGTCAAGATAA
AGCTGTAGAAATGGTTTCTCGTGCCATTCGTCGTAATCGAGCTGGTTTTGATGATGGTAATCGTCCAATTGGTAGCTTCC
TATTTGTCGGTCCTACTGGTGTGAGTAAAACAGAGCTTGCCAAACAGTTAGCCATTGATTTATTTGGTAATAAAGAGGCA
CTGATTCGACTTGATATGAGTGAATATAGTGATACTACTGCTGTTTCTAAAATGATTGGTACAACTGCTGGTTATGTCGG
TTATGACGATAATTCAAATACATTAACTGAAAAAGTACGACGCAATCCATATTCAGTCATTCTATTTGATGAAATTGAAA
AGGCTAATCCACAAATATTAACATTATTACTTCAAGTGATGGATGATGGTAATTTGACTGATGGTCAAGGTAATGTCATC
AACTTTAAAAATACAATTATTATTTGTACATCAAATGCTGGCTTTGGCAATGGCAATGACACTGAAGAAAAAGATATTAT
GCATGAAATGAAAAAATTCTTCCGCCCTGAATTCCTTAACCGCTTCAACGGCATCGTTGAATTCTTACATTTAGATAAAG
ATGCATTACAAGATATCGTCAACTTGTTATTAGACGATGTACAAGTTACATTAGATAAAAAAGGTATTACGATGGACGTT
TCACAAGATGCGAAAGATTGGTTAATTGAAGAAGGTTATGATGAAGAATTAGGCGCACGCCCATTAAGACGTATTGTTGA
ACAACAAGTGCGTGACAAAATAACAGATTATTATTTAGATCATACAGACGTTAAACATGTGGATATAGATGTTGAGGATA
ACGAATTAGTCGTAAAAGGTAAATAA

Domains

Predicted by InterProScan.

• AAA lid domain (AAA_lid_9) (264-363)

• ATPase family associated with various cellular activities (AAA) (AAA) (123-257)

• AAA domain (Cdc48 subfamily) (AAA_2) (448-603)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (611-682)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus mutans UA159	48.452	92.154	0.447
clpE	Streptococcus pneumoniae TIGR4	47.573	88.16	0.419
clpE	Streptococcus pneumoniae R6	47.65	88.017	0.419
clpE	Streptococcus pneumoniae D39	47.65	88.017	0.419
clpE	Streptococcus pneumoniae Rx1	47.65	88.017	0.419
clpC	Lactococcus lactis subsp. cremoris KW2	46.497	89.586	0.417
clpC	Bacillus subtilis subsp. subtilis str. 168	43.969	93.438	0.411
clpC	Streptococcus thermophilus LMD-9	44.8	89.158	0.399
clpC	Streptococcus thermophilus LMG 18311	44.48	89.158	0.397
clpC	Streptococcus pneumoniae TIGR4	43.52	89.158	0.388
clpC	Streptococcus pneumoniae Rx1	43.52	89.158	0.388
clpC	Streptococcus pneumoniae D39	43.52	89.158	0.388
clpC	Streptococcus mutans UA159	43.74	87.732	0.384
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	42.536	88.873	0.378