Detailed information NTG0997587

Bioinformatically predicted

Overview

• Name: uvrA
• Type: Machinery gene
• Locus tag: EL041_RS23560
• Genome accession: NZ_LR134092
• Coordinates: 4881391..4884213 (+)
• Length: 940 a.a.
• NCBI ID: WP_001033156.1
• Uniprot ID: -
• Organism: Escherichia coli strain NCTC10444
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 4876391..4889213

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL041_RS23530	soxR	4876479..4876943 (-)	465	WP_126298087.1	redox-sensitive transcriptional activator SoxR	-
EL041_RS23535 (NCTC10444_04658)	soxS	4877029..4877352 (+)	324	WP_000019358.1	superoxide response transcriptional regulator SoxS	-
EL041_RS23540 (NCTC10444_04659)	pdeC	4877355..4878941 (-)	1587	WP_000019517.1	c-di-GMP phosphodiesterase PdeC	-
EL041_RS23545 (NCTC10444_04660)	yjcB	4879370..4879651 (+)	282	WP_001362074.1	YjcB family protein	-
EL041_RS23550 (NCTC10444_04661)	-	4879922..4880398 (+)	477	WP_001121509.1	hypothetical protein	-
EL041_RS23555 (NCTC10444_04662)	ssb1	4880600..4881136 (-)	537	WP_000168305.1	single-stranded DNA-binding protein SSB1	-
EL041_RS23560 (NCTC10444_04663)	uvrA	4881391..4884213 (+)	2823	WP_001033156.1	excinuclease ABC subunit UvrA	Machinery gene
EL041_RS23565 (NCTC10444_04664)	yjbR	4884248..4884604 (-)	357	WP_000155657.1	MmcQ/YjbR family DNA-binding protein	-
EL041_RS23570 (NCTC10444_04665)	yjbQ	4884608..4885024 (-)	417	WP_000270375.1	secondary thiamine-phosphate synthase enzyme YjbQ	-
EL041_RS23575 (NCTC10444_04666)	aphA	4885135..4885848 (-)	714	WP_001226920.1	acid phosphatase AphA	-
EL041_RS26090	-	4886266..4886470 (+)	205	Protein_4565	hypothetical protein	-
EL041_RS23585 (NCTC10444_04668)	tyrB	4886972..4888165 (-)	1194	WP_000486960.1	aromatic amino acid transaminase	-

Sequence

Protein

• Length: 940 a.a.
• Molecular weight: 103866.55 Da
• Isoelectric Point: 6.6712

>NTDB_id=997587 EL041_RS23560 WP_001033156.1 4881391..4884213(+) (uvrA) [Escherichia coli strain NCTC10444]
MNKIEVRGARTHNLKNINLVIPRDKLIVVTGLSGSGKSSLAFDTLYAEGQRRYVESLSAYARQFLSLMEKPDVDHIEGLS
PAISIEQKSTSHNPRSTVGTITEIHDYLRLLFARVGEPRCPDHDVPLAAQTVSQMVDNVLSQPEGKRLMLLAPIIKERKG
EHTKTLENLASQGYIRARIDGEVCDLSDPPKLELQKKHTIEVVVDRFKVRDDLTQRLAESFETALELSGGTAVVADMDDP
KAEELLFSANFACPICGYSMRELEPRLFSFNNPAGACPTCDGLGVQQYFDPDRVIQNPELSLAGGAIRGWDRRNFYYFQM
LKSLADHYKFDVEAPWGSLSANVHKVVLYGSGKENIEFKYMNDRGDTSIRRHPFEGVLHNMERRYKETESSAVREELAKF
ISNRPCASCEGTRLRREARHVYVENTPLPAISDMSIGHAMEFFNNLKLAGQRAKIAEKILKEIGDRLKFLVNVGLNYLTL
SRSAETLSGGEAQRIRLASQIGAGLVGVMYVLDEPSIGLHQRDNERLLGTLIHLRDLGNTVIVVEHDEDAIRAADHVIDI
GPGAGVHGGEVVAEGPLEAIMAVPESLTGQYMSGKRKIEVPKKRVPANPEKVLKLTGARGNNLKDVTLTLPVGLFTCITG
VSGSGKSTLINDTLFPIAQRQLNGATIAEPAPYRDIQGLEHFDKVIDIDQSPIGRTPRSNPATYTGVFTPVRELFAGVPE
SRARGYTPGRFSFNVRGGRCEACQGDGVIKVEMHFLPDIYVPCDQCKGKRYNRETLEIKYKGKTIHEVLDMTIEEAREFF
DAVPALARKLQTLMDVGLTYIRLGQSATTLSGGEAQRVKLARELSKRGTGQTLYILDEPTTGLHFADIQQLLDVLHKLRD
QGNTIVVIEHNLDVIKTADWIVDLGPEGGSGGGEILVSGTPETVAECEASHTARFLKPML

Nucleotide

• Length: 2823 bp

>NTDB_id=997587 EL041_RS23560 WP_001033156.1 4881391..4884213(+) (uvrA) [Escherichia coli strain NCTC10444]
ATGAATAAGATCGAAGTTCGGGGCGCCCGCACCCATAATCTCAAAAACATCAACCTCGTTATCCCCCGCGACAAGCTCAT
TGTCGTGACCGGGCTTTCGGGCTCTGGCAAATCCTCGCTCGCTTTCGACACCTTATATGCCGAAGGGCAGCGCCGTTACG
TTGAATCCCTTTCCGCCTACGCGCGGCAGTTTCTGTCACTGATGGAAAAGCCGGACGTCGATCATATTGAGGGGCTTTCT
CCTGCCATCTCAATTGAGCAGAAATCGACGTCTCATAACCCGCGTTCTACGGTGGGGACAATCACCGAAATCCACGACTA
TTTGCGTTTGTTGTTCGCCCGCGTCGGCGAACCGCGCTGTCCGGACCACGACGTCCCGCTGGCGGCGCAAACCGTCAGCC
AGATGGTGGATAACGTGCTGTCGCAGCCGGAAGGCAAGCGTCTGATGCTGCTCGCGCCAATCATTAAAGAGCGCAAAGGC
GAACACACCAAAACGCTGGAGAACCTGGCAAGCCAGGGTTACATCCGTGCTCGTATTGATGGCGAAGTCTGCGATCTTTC
CGATCCGCCGAAACTGGAACTGCAAAAGAAACACACTATTGAAGTGGTGGTTGATCGCTTCAAGGTGCGTGACGATCTTA
CCCAACGTCTGGCCGAGTCGTTTGAAACCGCGCTGGAGCTTTCCGGTGGTACCGCGGTAGTGGCGGATATGGACGACCCG
AAAGCGGAAGAGCTGCTGTTTTCCGCCAACTTCGCCTGCCCAATTTGCGGCTACAGTATGCGTGAACTGGAGCCGCGACT
GTTTTCGTTTAACAACCCGGCAGGGGCCTGCCCGACCTGTGACGGCCTCGGCGTACAGCAATATTTCGATCCTGACCGCG
TGATCCAAAACCCGGAACTGTCGCTGGCAGGTGGTGCGATCCGTGGCTGGGATCGCCGCAACTTCTATTATTTCCAGATG
CTGAAATCGCTGGCAGATCACTATAAGTTCGACGTCGAAGCGCCGTGGGGCAGCTTGAGCGCGAACGTGCATAAAGTGGT
GTTGTACGGTTCTGGCAAAGAAAACATTGAATTCAAATACATGAACGATCGTGGCGATACCTCCATCCGTCGTCATCCGT
TCGAAGGCGTGCTGCACAATATGGAGCGCCGTTATAAAGAGACAGAATCCAGTGCGGTACGTGAAGAATTAGCCAAGTTT
ATCAGCAATCGCCCGTGCGCCAGCTGCGAAGGAACGCGTCTGCGTCGGGAAGCGCGCCACGTGTATGTCGAGAATACGCC
GCTGCCCGCTATCTCCGACATGAGCATCGGTCATGCGATGGAATTCTTCAACAATCTCAAACTCGCAGGTCAGCGGGCGA
AGATTGCGGAAAAAATTCTTAAAGAGATCGGCGATCGTTTGAAATTCCTCGTTAACGTCGGCCTGAATTACCTGACACTT
TCCCGCTCGGCAGAAACGCTTTCCGGCGGTGAAGCCCAGCGTATCCGTCTGGCGAGCCAGATTGGTGCGGGCCTGGTTGG
CGTTATGTATGTACTGGACGAGCCGTCTATCGGCCTGCACCAGCGCGATAACGAGCGCCTGTTGGGTACGCTTATCCATC
TGCGCGATCTCGGTAATACCGTGATTGTGGTGGAGCACGACGAAGACGCGATTCGCGCCGCAGACCATGTGATCGACATT
GGCCCGGGCGCAGGTGTTCACGGCGGTGAAGTGGTCGCAGAAGGTCCGCTGGAAGCGATTATGGCGGTGCCGGAGTCGTT
GACCGGGCAGTACATGAGCGGTAAACGCAAGATTGAAGTGCCGAAGAAACGCGTTCCGGCGAATCCGGAAAAAGTGCTGA
AGCTGACAGGCGCACGCGGTAATAACCTGAAAGACGTGACGCTGACGCTGCCAGTCGGTCTGTTTACCTGCATCACAGGG
GTTTCAGGTTCCGGTAAATCGACGCTGATTAACGACACACTGTTCCCGATTGCCCAACGCCAGTTGAATGGGGCGACCAT
CGCCGAACCAGCACCGTATCGCGATATTCAGGGGCTGGAGCATTTCGATAAAGTGATCGATATCGACCAAAGCCCAATTG
GTCGTACTCCGCGTTCTAACCCGGCGACCTATACCGGCGTGTTTACACCTGTGCGCGAACTGTTTGCGGGCGTACCGGAA
TCCCGTGCTCGTGGTTATACGCCAGGACGTTTCAGCTTTAACGTCCGTGGCGGACGCTGCGAGGCCTGTCAGGGCGATGG
CGTGATCAAAGTGGAGATGCACTTCCTGCCGGACATTTACGTGCCGTGCGACCAGTGCAAAGGTAAACGCTATAACCGTG
AAACGCTGGAGATTAAGTACAAAGGCAAAACCATCCACGAAGTGCTGGATATGACCATCGAAGAGGCGCGTGAGTTCTTT
GATGCGGTGCCAGCTCTGGCGCGTAAGCTGCAAACGTTGATGGACGTTGGCCTGACGTACATTCGCCTGGGGCAGTCCGC
AACCACACTTTCTGGTGGTGAAGCCCAGCGCGTGAAGCTGGCGCGTGAGCTGTCAAAACGCGGCACCGGGCAGACACTGT
ATATTCTCGACGAGCCGACCACCGGTCTGCACTTCGCCGATATTCAGCAACTGCTCGACGTACTGCATAAACTGCGCGAT
CAGGGCAACACCATTGTGGTGATTGAGCACAATCTCGACGTGATCAAAACCGCTGACTGGATTGTCGACCTGGGACCAGA
AGGCGGCAGTGGCGGCGGCGAAATCCTCGTCTCCGGTACGCCAGAAACCGTCGCGGAGTGCGAAGCTTCGCATACGGCAC
GCTTCCTCAAGCCGATGCTGTAA

Domains

Predicted by InterProScan.

• UvrA DNA-binding domain (UvrA_DNA-bind) (290-399)

• ABC transporter (ABC_tran) (806-860)

• UvrA interaction domain (UvrA_inter) (130-237)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
uvrA	Streptococcus pneumoniae R6	57.264	100	0.574
uvrA	Streptococcus pneumoniae TIGR4	57.264	100	0.574
uvrA	Streptococcus pneumoniae D39	57.264	100	0.574