Detailed information NTG0997435

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: ABC804_RS06435
• Genome accession: NZ_CP155536
• Coordinates: 1207003..1207956 (-)
• Length: 317 a.a.
• NCBI ID: WP_000495909.1
• Uniprot ID: A0A0H2UPP6
• Organism: Streptococcus pneumoniae strain M264-3
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 1202003..1212956

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ABC804_RS06410 (ABC804_06405)	-	1202491..1202586 (-)	96	Protein_1213	IS630 family transposase	-
ABC804_RS06415 (ABC804_06410)	-	1202999..1203340 (+)	342	Protein_1214	IS3 family transposase	-
ABC804_RS06420 (ABC804_06415)	prsA	1203459..1204400 (-)	942	WP_000727935.1	peptidylprolyl isomerase PrsA	-
ABC804_RS06425 (ABC804_06420)	-	1204467..1205180 (-)	714	WP_000230399.1	O-methyltransferase	-
ABC804_RS06430 (ABC804_06425)	pepF	1205182..1206984 (-)	1803	WP_000244134.1	oligoendopeptidase F	Regulator
ABC804_RS06435 (ABC804_06430)	coiA	1207003..1207956 (-)	954	WP_000495909.1	competence protein CoiA	Machinery gene
ABC804_RS06440 (ABC804_06435)	tehB	1208029..1208889 (-)	861	WP_000413769.1	SAM-dependent methyltransferase TehB	-
ABC804_RS06445 (ABC804_06440)	smpB	1208905..1209372 (-)	468	WP_001051753.1	SsrA-binding protein SmpB	-
ABC804_RS06450 (ABC804_06445)	rnr	1209335..1211689 (-)	2355	WP_000654920.1	ribonuclease R	-
ABC804_RS06455 (ABC804_06450)	secG	1211791..1212024 (-)	234	WP_000282517.1	preprotein translocase subunit SecG	-
ABC804_RS06460 (ABC804_06455)	rpmG	1212064..1212213 (-)	150	WP_001809104.1	50S ribosomal protein L33	-

Sequence

Protein

• Length: 317 a.a.
• Molecular weight: 38243.86 Da
• Isoelectric Point: 8.9865

>NTDB_id=997435 ABC804_RS06435 WP_000495909.1 1207003..1207956(-) (coiA) [Streptococcus pneumoniae strain M264-3]
MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTHFAHKSLKDCDFFFENESPEHLANKESLYHWLKKETK
VQLEYPLSELKQIADVFVNGNLALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
YVWELDKEKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKRQKISHFTVSEDKDICRYIRQQLYYQNLFWM
KEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIEQDLTSYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE

Nucleotide

• Length: 954 bp

>NTDB_id=997435 ABC804_RS06435 WP_000495909.1 1207003..1207956(-) (coiA) [Streptococcus pneumoniae strain M264-3]
ATGTTTGTTGCGAGAGATGCTAGGGGAGAATTGGTAAATGTGTTAGAGGATAAACTTGAGAAGCAAGCATACACCTGCCC
AGCTTGTGGAGGCCAGCTCCATTTGCGTCAAGGACCAAGTGTACGGACGCATTTTGCCCATAAATCCTTAAAAGACTGTG
ATTTTTTCTTTGAAAATGAAAGTCCAGAACACCTGGCCAATAAGGAATCCCTCTATCACTGGTTGAAAAAAGAGACAAAG
GTTCAATTAGAGTACCCGCTTTCAGAACTTAAACAGATTGCGGATGTATTTGTAAATGGCAATCTAGCTCTAGAAGTTCA
GTGTAGTCCCTTGCCTCAGAAAGTCCTTAAAGAGCGAAGTGAGGGCTATCGTAGTCAGGGTTACCAAGTACTGTGGTTGC
TGGGTCAAAAACTGTGGCTCAAGGAGCGTTTGACTCGTCTACAGCAAGGTTTTCTTTATTTCAGTCAAAACATGGGCTTT
TATGTTTGGGAATTAGACAAGGAAAAACAAGTTTTAAGACTCAAATACCTGATTTACCAGGATCTCCGCGGTAAACTCCA
TTATCAAATCAAGGAATTTTCCTATGGTCAAGGTAGTTTATTGGAAATATTGCGTCTTCCCTATAAGAGACAAAAAATAT
CTCATTTTACAGTTTCTGAGGACAAGGACATCTGTCGCTATATCCGGCAACAACTTTATTATCAAAATCTCTTTTGGATG
AAAGAACAAGCAGAAGCCTATCAAAAGGGAGAAAATATCCTGACTTATGGACTGAAAGAATGGTATCCACAAATTCGACC
AATAGTGGGCAAATTTTTCCAGATTGAACAAGACTTGACTAGCTATTATCAGCACTTTTATACCTATTACCAAAAAAATC
CTCAAAATGATTGGCAAAAGCTTTATCCACCAGCCTTTTATCAGCAATATTTCTTGAAAAATATGGTAGAATAG

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (13-263)

3D structure

• AlphaFold DB: A0A0H2UPP6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Streptococcus pneumoniae TIGR4	100	100	1
coiA	Streptococcus pneumoniae Rx1	99.369	100	0.994
coiA	Streptococcus pneumoniae D39	99.369	100	0.994
coiA	Streptococcus pneumoniae R6	99.369	100	0.994
coiA	Streptococcus mitis NCTC 12261	89.274	100	0.893
coiA	Lactococcus lactis subsp. cremoris KW2	42.593	100	0.435