Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   GZL_RS38525 Genome accession   NZ_CP003987
Coordinates   9030072..9030728 (-) Length   218 a.a.
NCBI ID   WP_052287176.1    Uniprot ID   A0ABY8AI37
Organism   Streptomyces sp. 769     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 9025072..9035728
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GZL_RS38505 (GZL_08409) kdsA 9025604..9026419 (+) 816 WP_039642803.1 3-deoxy-8-phosphooctulonate synthase -
  GZL_RS38510 (GZL_08410) - 9026476..9027039 (+) 564 WP_052287175.1 SIS domain-containing protein -
  GZL_RS38515 (GZL_08411) kdsB 9027039..9027719 (+) 681 WP_203232639.1 3-deoxy-manno-octulosonate cytidylyltransferase -
  GZL_RS38520 (GZL_08413) - 9028073..9029362 (-) 1290 WP_239010268.1 hypothetical protein -
  GZL_RS38525 (GZL_08415) vraR 9030072..9030728 (-) 657 WP_052287176.1 response regulator transcription factor Regulator
  GZL_RS38530 (GZL_08416) - 9030846..9032084 (-) 1239 WP_052287177.1 histidine kinase -
  GZL_RS38535 (GZL_08417) - 9032246..9032770 (+) 525 WP_039638923.1 hypothetical protein -
  GZL_RS49060 (GZL_08420) - 9033644..9034009 (+) 366 WP_039638924.1 MMPL family transporter -
  GZL_RS49065 (GZL_08421) - 9034034..9034183 (+) 150 WP_159030966.1 hypothetical protein -
  GZL_RS49070 (GZL_08422) - 9034464..9034715 (-) 252 WP_159030967.1 hypothetical protein -
  GZL_RS38545 (GZL_08423) - 9034731..9035684 (-) 954 WP_039642811.1 alkylmercury lyase family protein -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23021.38 Da        Isoelectric Point: 6.2354

>NTDB_id=99733 GZL_RS38525 WP_052287176.1 9030072..9030728(-) (vraR) [Streptomyces sp. 769]
MNHHTVPDDAAAAHPIRVLLADDHPVVREGLSAMLESAPDITVAGQAASGEEAVTLAGRLRPDIVLLDLRMGGMDGVAAT
GHILRQAPGSRVVIVTTYESDTDILRAVEEGAAGYLLKGSTRAELIDAVRAAARGETVLTPSLAPKLFRSRTVDAPPLSD
RETEVLRLVGQGLTNAAIGTKLFIGEATVKTHLLRAYRKLDVTDRTAAVVTALERGLI

Nucleotide


Download         Length: 657 bp        

>NTDB_id=99733 GZL_RS38525 WP_052287176.1 9030072..9030728(-) (vraR) [Streptomyces sp. 769]
ATGAACCACCACACAGTGCCCGATGACGCGGCCGCGGCCCACCCGATCCGGGTCCTCCTCGCGGACGACCACCCGGTCGT
CCGCGAGGGCCTGTCCGCCATGCTGGAATCCGCCCCGGACATCACCGTCGCCGGACAGGCCGCATCCGGCGAGGAAGCGG
TGACCCTGGCGGGGCGGTTGCGGCCCGACATCGTGCTGCTCGACCTGCGGATGGGCGGGATGGACGGCGTAGCGGCCACC
GGGCACATCCTGCGCCAGGCGCCCGGCAGCAGGGTCGTCATCGTCACCACCTACGAAAGCGACACGGACATCCTGCGCGC
CGTGGAGGAGGGCGCGGCCGGCTATCTCCTCAAGGGGAGTACCCGGGCAGAACTCATCGACGCCGTACGGGCGGCAGCCC
GCGGCGAGACCGTGCTGACCCCGTCGCTCGCTCCCAAGCTGTTCCGGTCGCGGACGGTGGACGCCCCACCGCTCTCCGAT
CGGGAAACCGAAGTGCTGCGACTGGTCGGCCAGGGCCTCACCAACGCGGCGATCGGCACCAAGCTGTTCATCGGCGAGGC
CACCGTGAAGACGCACCTGCTGCGCGCCTATCGGAAACTGGACGTGACGGACCGGACCGCGGCCGTCGTGACGGCCCTGG
AACGCGGCCTGATCTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(157-212)

Response regulator receiver domain (Response_reg)

(18-130)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

39.806

94.495

0.376

Multiple sequence alignment