Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   ELZ49_RS10920 Genome accession   NZ_LR134086
Coordinates   2120228..2120944 (+) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   P0A0I7
Organism   Staphylococcus aureus strain NCTC13142     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2115228..2125944
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ELZ49_RS10895 (NCTC13142_02107) istA 2115799..2117034 (-) 1236 WP_001215400.1 IS21 family transposase -
  ELZ49_RS14970 hld 2117817..2117897 (-) 81 WP_000046022.1 delta-hemolysin -
  ELZ49_RS10905 (NCTC13142_02109) agrB 2118186..2118755 (+) 570 WP_001105713.1 accessory gene regulator AgrB -
  ELZ49_RS10910 (NCTC13142_02110) agrD 2118752..2118892 (+) 141 WP_001093929.1 cyclic lactone autoinducer peptide AgrD -
  ELZ49_RS10915 (NCTC13142_02111) agrC 2118917..2120209 (+) 1293 WP_001670396.1 quorum-sensing sensor histidine kinase AgrC -
  ELZ49_RS10920 (NCTC13142_02112) agrA 2120228..2120944 (+) 717 WP_000688492.1 quorum-sensing response regulator AgrA Regulator
  ELZ49_RS10925 - 2121016..2121123 (+) 108 WP_031789494.1 hypothetical protein -
  ELZ49_RS10930 (NCTC13142_02113) - 2121312..2122271 (-) 960 WP_001253301.1 carbohydrate kinase family protein -
  ELZ49_RS10935 (NCTC13142_02114) - 2122268..2123752 (-) 1485 WP_000141410.1 sucrose-6-phosphate hydrolase -
  ELZ49_RS10940 (NCTC13142_02115) - 2123901..2124851 (-) 951 WP_000790322.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=997243 ELZ49_RS10920 WP_000688492.1 2120228..2120944(+) (agrA) [Staphylococcus aureus strain NCTC13142]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=997243 ELZ49_RS10920 WP_000688492.1 2120228..2120944(+) (agrA) [Staphylococcus aureus strain NCTC13142]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATCCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCATAGTGAACTTACGTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACACGTATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATCGAATCTATAG
ATTCGAAAGAGCGCATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  PDB 3BS1
  PDB 4G4K

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1

Multiple sequence alignment