Detailed information NTG0997194

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: ABC814_RS09810
• Genome accession: NZ_CP155533
• Coordinates: 1899322..1900359 (-)
• Length: 345 a.a.
• NCBI ID: WP_012677144.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain Spn1439-106
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1894322..1905359

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ABC814_RS09785 (ABC814_09785)	-	1895123..1896454 (-)	1332	WP_000390048.1	hemolysin family protein	-
ABC814_RS09790 (ABC814_09790)	endA	1896683..1897507 (-)	825	WP_001036779.1	DNA-entry nuclease EndA	Machinery gene
ABC814_RS09795 (ABC814_09795)	-	1897546..1897734 (-)	189	WP_001813390.1	DNA-directed RNA polymerase subunit beta	-
ABC814_RS09800 (ABC814_09800)	murA	1897727..1899010 (-)	1284	WP_000358028.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
ABC814_RS09805 (ABC814_09805)	-	1899034..1899264 (-)	231	WP_000250392.1	DUF1146 family protein	-
ABC814_RS09810 (ABC814_09810)	sepM	1899322..1900359 (-)	1038	WP_012677144.1	SepM family pheromone-processing serine protease	Regulator
ABC814_RS09815 (ABC814_09815)	coaD	1900343..1900831 (-)	489	WP_001280753.1	pantetheine-phosphate adenylyltransferase	-
ABC814_RS09820 (ABC814_09820)	rsmD	1900821..1901360 (-)	540	WP_001819515.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
ABC814_RS09825 (ABC814_09825)	asnA	1901425..1902417 (-)	993	WP_000747993.1	aspartate--ammonia ligase	-
ABC814_RS09830 (ABC814_09830)	-	1902529..1903212 (-)	684	WP_001016917.1	Bax inhibitor-1/YccA family protein	-
ABC814_RS09835 (ABC814_09835)	-	1903268..1904008 (-)	741	WP_000152678.1	RNA methyltransferase	-
ABC814_RS09840 (ABC814_09840)	-	1904042..1904320 (+)	279	WP_001174613.1	acylphosphatase	-
ABC814_RS09845 (ABC814_09845)	yidC	1904398..1905324 (+)	927	WP_000835955.1	membrane protein insertase YidC	-

Sequence

Protein

• Length: 345 a.a.
• Molecular weight: 37549.57 Da
• Isoelectric Point: 5.0724

>NTDB_id=997194 ABC814_RS09810 WP_012677144.1 1899322..1900359(-) (sepM) [Streptococcus pneumoniae strain Spn1439-106]
MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLKVNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFT
DIRSAQETTGGSSDVEFLRINQFYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVISNVPISFSTAGIGGPSAGLMFSL
AIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGIDKKVVASARAGAAIFFTPDNPVSEEEQKAHPDAKNNYQTALEAAK
TIKTDMKIVPVKTLQDAIDYLKNNP

Nucleotide

• Length: 1038 bp

>NTDB_id=997194 ABC814_RS09810 WP_012677144.1 1899322..1900359(-) (sepM) [Streptococcus pneumoniae strain Spn1439-106]
ATGAAAAAAAAGATTAGATGGCCCTTATACGTCATTGCGGCCTTGATTGTGACTTTCTTGGCATTTGTAGTGCCCTTGCC
TTATTATATAGAGGTTCCAGGTGGTTCGGAAGATATTCGCCAAGTCCTTAAAGTAAATGACACAGAAGATAAGGAAGCTG
GTGCCTATCAATTCGTTACGGTTGGTGTTCAACATGCCACTTTAGCTCATATGATTTATGCTTGGTTGACACCTTTTACA
GATATTCGTAGTGCTCAGGAGACTACAGGTGGTTCTTCCGATGTTGAATTTCTGCGAATCAATCAATTCTACATGCAAAC
ATCGCAAAATATGGCCAAGTATCAAGGACTAAAAACAGCTGGTAAGGATATCGAACTCAAGTACTTTGGAGTTTATGTTT
TGAATGTGACGGATAATTCAACCTTTAAAGGGATTCTCAATATCTCTGATACAGTCACAGCAGTCAATGATCAGACCTTT
GATAGTTCCAAAGACTTGATTGATTACGTCAGTTCTCAAAAATTAGGGGATTCCGTCAAGGTCACCTATGAAGAGGATGG
GCAAACCAAGTCTGCAGAAGGAAAGATTATCACCTTGGAAAATGGCAAAAATGGAATTGGAATCGGCTTGATTGACCGTA
CAGAGGTAATCAGCAATGTCCCAATTAGCTTTTCAACAGCTGGTATTGGCGGCCCAAGTGCTGGTCTCATGTTTAGTCTA
GCTATCTATACTCAAATAGCTCACCCAGATCTTCGTAATGGTCGTATTGTTGCCGGTACAGGTACCATTGACCGCGATGG
TAATGTGGGAGACATTGGAGGTATTGATAAGAAGGTTGTAGCTTCGGCTAGGGCAGGTGCTGCTATTTTCTTTACTCCTG
ATAACCCTGTTAGCGAAGAAGAACAAAAGGCGCATCCGGACGCGAAAAACAACTACCAAACAGCCCTAGAAGCGGCTAAA
ACAATCAAGACGGATATGAAAATCGTGCCCGTTAAAACCCTACAAGATGCGATTGATTACTTGAAAAACAATCCCTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (130-193)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (230-296)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	59.357	99.13	0.588