Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   GZL_RS13970 Genome accession   NZ_CP003987
Coordinates   3331178..3331864 (+) Length   228 a.a.
NCBI ID   WP_039632360.1    Uniprot ID   A0A2N8PCI4
Organism   Streptomyces sp. 769     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 3326178..3336864
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GZL_RS13955 (GZL_03111) - 3327215..3328351 (-) 1137 WP_039632356.1 glycosyltransferase family 4 protein -
  GZL_RS13960 (GZL_03112) - 3328348..3329544 (-) 1197 WP_239010044.1 glycosyltransferase 87 family protein -
  GZL_RS13965 (GZL_03113) - 3330030..3331184 (+) 1155 WP_039632358.1 histidine kinase -
  GZL_RS13970 (GZL_03114) vraR 3331178..3331864 (+) 687 WP_039632360.1 response regulator transcription factor Regulator
  GZL_RS13975 (GZL_03115) - 3331980..3333050 (-) 1071 WP_039632362.1 ABC transporter ATP-binding protein -
  GZL_RS13980 (GZL_03116) - 3333051..3334700 (-) 1650 WP_039632364.1 iron ABC transporter permease -
  GZL_RS13985 (GZL_03117) - 3334754..3335869 (-) 1116 WP_039632366.1 thiamine ABC transporter substrate-binding protein -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 24695.53 Da        Isoelectric Point: 6.3499

>NTDB_id=99684 GZL_RS13970 WP_039632360.1 3331178..3331864(+) (vraR) [Streptomyces sp. 769]
MVIRAIVADDQAIVRTGFVNLLGTQDDIEVVGEAEDGVQAVRIAAEQRPDLALLDIRMPHKNGIEAAREITRASGGATKA
LMLTTFGLDEYVYDALAAGASGFLLKDTTFPELLHAVRVVAEGNALLAPELTKRLIAEFVKQRSAPVPVRTVEELTGREV
EVLVHIAQGLSNAEIATRLTITDHTVKTHINRLFTKMGLRDRAQAVILAYELGLVVPQGRRPAPPPRA

Nucleotide


Download         Length: 687 bp        

>NTDB_id=99684 GZL_RS13970 WP_039632360.1 3331178..3331864(+) (vraR) [Streptomyces sp. 769]
GTGGTGATCAGAGCAATCGTGGCCGACGACCAGGCCATCGTCCGCACCGGGTTTGTCAATCTCCTGGGCACCCAGGACGA
CATCGAGGTGGTGGGCGAGGCCGAGGACGGTGTCCAGGCGGTCCGGATCGCCGCCGAGCAGCGTCCGGACCTCGCGCTGC
TCGACATCCGGATGCCGCACAAGAACGGTATCGAGGCTGCCCGCGAGATCACCCGGGCGTCCGGTGGTGCCACCAAGGCG
CTGATGCTGACGACGTTCGGGCTCGACGAGTATGTGTACGACGCGCTGGCGGCCGGGGCGAGCGGGTTCCTGCTGAAGGA
CACCACGTTTCCCGAACTGCTGCATGCCGTAAGGGTCGTGGCGGAGGGCAATGCGCTGCTGGCGCCCGAGCTGACCAAGC
GGTTGATCGCGGAGTTCGTCAAGCAGCGGTCGGCACCGGTTCCCGTGCGCACGGTGGAGGAGCTGACCGGCCGTGAGGTG
GAGGTGCTCGTCCACATCGCCCAGGGACTGTCCAACGCGGAGATCGCCACCCGGCTGACGATCACCGATCACACCGTCAA
GACCCACATCAACCGGCTCTTCACAAAGATGGGCCTCCGTGACCGCGCTCAGGCGGTGATCCTCGCCTACGAACTGGGGC
TGGTCGTCCCCCAAGGCCGACGCCCCGCCCCTCCCCCACGCGCCTAG

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(6-117)

Bacterial regulatory proteins, luxR family (GerE)

(155-209)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2N8PCI4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

40.278

94.737

0.382