Detailed information NTG0996639

Bioinformatically predicted

Overview

• Name: cytR
• Type: Regulator
• Locus tag: EL014_RS21445
• Genome accession: NZ_LR134000
• Coordinates: 4408502..4409527 (+)
• Length: 341 a.a.
• NCBI ID: WP_000644904.1
• Uniprot ID: P0ACN8
• Organism: Escherichia coli strain NCTC9066
• Function: promote competence gene expression (predicted from homology) Competence regulation

Genomic Context

Location: 4403502..4414527

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL014_RS21435 (NCTC9066_04267)	rpmE	4405733..4405945 (-)	213	WP_000710769.1	50S ribosomal protein L31	-
EL014_RS21440 (NCTC9066_04268)	priA	4406148..4408346 (+)	2199	WP_001300388.1	primosomal protein N'	Machinery gene
EL014_RS21445 (NCTC9066_04269)	cytR	4408502..4409527 (+)	1026	WP_000644904.1	DNA-binding transcriptional regulator CytR	Regulator
EL014_RS21450 (NCTC9066_04270)	ftsN	4409619..4410578 (+)	960	WP_000068828.1	cell division protein FtsN	-
EL014_RS21455 (NCTC9066_04271)	hslV	4410671..4411201 (+)	531	WP_000208242.1	ATP-dependent protease subunit HslV	-
EL014_RS21460 (NCTC9066_04272)	hslU	4411211..4412542 (+)	1332	WP_001293341.1	HslU--HslV peptidase ATPase subunit	-
EL014_RS21465 (NCTC9066_04273)	menA	4412609..4413535 (+)	927	WP_000139496.1	1,4-dihydroxy-2-naphthoate polyprenyltransferase	-
EL014_RS21470 (NCTC9066_04274)	rraA	4413628..4414113 (+)	486	WP_000872908.1	ribonuclease E activity regulator RraA	-
EL014_RS21475 (NCTC9066_04275)	zapB	4414198..4414443 (-)	246	WP_001296623.1	septal ring assembly protein ZapB	-

Sequence

Protein

• Length: 341 a.a.
• Molecular weight: 37819.78 Da
• Isoelectric Point: 6.3842

>NTDB_id=996639 EL014_RS21445 WP_000644904.1 4408502..4409527(+) (cytR) [Escherichia coli strain NCTC9066]
MKAKKQETAATMKDVALKAKVSTATVSRALMNPDKVSQATRNRVEKAAREVGYLPQPMGRNVKRNESRTILVIVPDICDP
FFSEIIRGIEVTAANHGYLVLIGDCAHQNQQEKTFIDLIITKQIDGMLLLGSRLPFDASIEEQRNLPPMVMANEFAPELE
LPTVHIDNLTAAFDAVNYLYEQGHKRIGCIAGPEEMPLCHYRLQGYVQALRRCGIMVDPQYIARGDFTFEAGSKAMQQLL
DLPQPPTAVFCHSDVMALGALSQAKRQGLKVPEDLSIIGFDNIDLTQFCDPPLTTIAQPRYEIGREAMLLLLDQMQGQHV
GSGSRLMDCELIIRGSTRALP

Nucleotide

• Length: 1026 bp

>NTDB_id=996639 EL014_RS21445 WP_000644904.1 4408502..4409527(+) (cytR) [Escherichia coli strain NCTC9066]
GTGAAAGCGAAGAAGCAGGAAACTGCCGCGACCATGAAAGACGTTGCCCTCAAGGCAAAAGTCTCTACAGCGACCGTCTC
CCGAGCATTAATGAATCCCGATAAAGTCTCCCAGGCCACCCGTAATCGGGTTGAAAAAGCGGCCCGGGAAGTGGGTTATT
TACCGCAGCCTATGGGGCGCAACGTCAAGCGTAATGAATCCCGCACCATTCTGGTGATTGTCCCGGATATCTGCGATCCC
TTCTTTAGCGAAATTATTCGCGGTATCGAAGTTACGGCGGCAAATCACGGATATCTGGTGCTGATTGGCGACTGTGCGCA
TCAAAATCAGCAGGAAAAAACCTTTATCGATTTGATCATCACCAAGCAAATTGATGGCATGTTGTTGCTGGGTTCAAGGC
TGCCGTTTGATGCCAGCATTGAGGAACAGCGTAATCTGCCGCCGATGGTGATGGCGAACGAATTTGCACCGGAGCTGGAG
CTGCCTACAGTTCATATCGACAATCTGACCGCCGCATTTGATGCAGTAAATTATTTATATGAGCAAGGGCATAAACGGAT
TGGCTGTATAGCCGGTCCCGAAGAGATGCCGCTGTGTCACTACCGCCTGCAAGGCTATGTTCAGGCGCTGCGTCGCTGCG
GCATTATGGTTGATCCGCAATACATCGCCCGTGGCGACTTCACCTTCGAAGCCGGAAGCAAAGCGATGCAGCAGCTGCTT
GATCTTCCACAACCGCCTACTGCTGTCTTCTGCCATAGCGATGTGATGGCGCTCGGCGCACTTTCTCAGGCAAAACGCCA
GGGGCTGAAAGTCCCGGAAGACCTTTCCATAATCGGTTTTGATAACATCGACCTGACGCAATTTTGTGATCCGCCGCTGA
CAACCATCGCGCAGCCGCGTTACGAAATCGGTCGGGAAGCTATGCTGTTATTGCTTGATCAAATGCAGGGGCAACACGTT
GGCAGTGGCTCTCGTTTAATGGACTGCGAACTTATCATCCGGGGATCAACACGCGCGTTACCTTAA

Domains

Predicted by InterProScan.

• Bacterial regulatory proteins, lacI family (LacI) (11-56)

• Periplasmic binding protein-like domain (Peripla_BP_3) (176-337)

3D structure

• AlphaFold DB: P0ACN8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
cytR	Vibrio parahaemolyticus RIMD 2210633	64.179	98.24	0.63
cytR	Vibrio cholerae C6706	65.443	95.894	0.628