Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   GZL_RS01130 Genome accession   NZ_CP003987
Coordinates   307543..308229 (+) Length   228 a.a.
NCBI ID   WP_039628708.1    Uniprot ID   -
Organism   Streptomyces sp. 769     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 302543..313229
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GZL_RS01110 (GZL_00281) - 303085..303537 (-) 453 WP_039628701.1 helix-turn-helix domain-containing protein -
  GZL_RS01115 (GZL_00282) - 303634..304899 (+) 1266 WP_203232497.1 MFS transporter -
  GZL_RS47280 (GZL_00283) - 305280..306275 (+) 996 WP_239009864.1 hypothetical protein -
  GZL_RS47285 (GZL_00284) - 306272..307546 (+) 1275 WP_039628705.1 histidine kinase -
  GZL_RS01130 (GZL_00285) vraR 307543..308229 (+) 687 WP_039628708.1 response regulator transcription factor Regulator
  GZL_RS01135 (GZL_00286) - 308293..309495 (-) 1203 WP_052286395.1 hypothetical protein -
  GZL_RS01140 (GZL_00287) - 309492..310541 (-) 1050 WP_039628710.1 aspartate-semialdehyde dehydrogenase -
  GZL_RS01145 (GZL_00288) - 310573..311547 (-) 975 WP_039639866.1 helix-turn-helix domain-containing protein -
  GZL_RS44135 (GZL_00289) - 311625..312056 (-) 432 WP_052286396.1 LuxR C-terminal-related transcriptional regulator -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 24793.49 Da        Isoelectric Point: 6.0256

>NTDB_id=99658 GZL_RS01130 WP_039628708.1 307543..308229(+) (vraR) [Streptomyces sp. 769]
MTAPTRPDTPPIRIVLADDEQMVRTALRAILGTEPDIEVVGEAATGAQAVPLVRELRPDIVLMDVRMPQIDGIRATECIL
AGTDNPPRIIVLTTFENDSYVYDALRAGASGFLLKRAHADELVQAVRLVARTDTLLFPTAIRTLAHTHTDRQGSRAEAER
LRERLSEREVEVLHLMAQGLSNTEIAQRMTVGAATVKTHVAGVLAKLGVRDRTQAVIAAYECGFVSPG

Nucleotide


Download         Length: 687 bp        

>NTDB_id=99658 GZL_RS01130 WP_039628708.1 307543..308229(+) (vraR) [Streptomyces sp. 769]
GTGACCGCCCCGACCCGGCCGGACACGCCGCCGATCCGGATCGTCCTGGCCGACGACGAGCAGATGGTCCGCACCGCCCT
GCGCGCCATTCTCGGCACCGAACCGGACATCGAGGTCGTCGGCGAGGCCGCCACCGGCGCCCAGGCAGTCCCCCTCGTCC
GCGAACTGCGCCCGGACATCGTGCTGATGGACGTGCGCATGCCCCAGATCGACGGCATCCGCGCCACCGAGTGCATCCTG
GCAGGCACCGACAACCCGCCACGCATCATCGTGCTCACCACCTTCGAGAACGACAGCTACGTATACGACGCACTCCGCGC
GGGCGCCTCCGGCTTCCTCCTCAAACGCGCGCATGCCGACGAACTCGTCCAGGCCGTACGTCTGGTGGCCCGCACCGACA
CGCTCCTGTTCCCCACGGCCATCCGCACCCTGGCTCATACGCACACCGATCGGCAGGGCTCGCGCGCAGAGGCGGAGCGG
CTGCGCGAGCGCCTCTCCGAGCGCGAGGTGGAGGTGCTGCACCTGATGGCGCAGGGCCTGTCGAACACCGAAATCGCCCA
GCGGATGACGGTGGGGGCAGCCACGGTCAAGACGCATGTGGCTGGGGTGCTGGCCAAGCTCGGCGTCCGGGACCGCACCC
AGGCGGTCATAGCCGCCTACGAGTGCGGATTCGTGTCACCAGGCTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(14-127)

Bacterial regulatory proteins, luxR family (GerE)

(165-218)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

41.395

94.298

0.39