Detailed information NTG0099624

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: QMM94_RS13395
• Genome accession: NZ_AP027134
• Coordinates: 2697329..2698216 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus strain JP008
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2692329..2703216

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QMM94_RS13365	-	2692343..2692435 (+)	93	WP_010956583.1	hypothetical protein	-
QMM94_RS13370 (JP008_25470)	-	2692543..2693040 (-)	498	WP_001065267.1	glutathione peroxidase	-
QMM94_RS13375 (JP008_25480)	-	2693050..2693310 (-)	261	WP_209205822.1	hypothetical protein	-
QMM94_RS13380	-	2693692..2693805 (-)	114	WP_072468803.1	hypothetical protein	-
QMM94_RS13385 (JP008_25490)	-	2694469..2696469 (-)	2001	WP_154283809.1	ABC transporter permease	-
QMM94_RS13390 (JP008_25500)	-	2696466..2697221 (-)	756	WP_154283810.1	ABC transporter ATP-binding protein	-
QMM94_RS13395 (JP008_25510)	braS	2697329..2698216 (-)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
QMM94_RS13400 (JP008_25520)	braR	2698227..2698892 (-)	666	WP_000697883.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
QMM94_RS13405 (JP008_25530)	-	2698918..2699118 (-)	201	WP_154283811.1	hypothetical protein	-
QMM94_RS13410 (JP008_25540)	-	2699316..2700740 (+)	1425	WP_000953731.1	alkaline phosphatase	-
QMM94_RS13875	-	2700800..2700901 (-)	102	WP_000731972.1	SE2200 family small protein	-
QMM94_RS13420 (JP008_25550)	-	2701023..2701478 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
QMM94_RS13425 (JP008_25560)	-	2701723..2702484 (-)	762	WP_154283812.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=99624 QMM94_RS13395 WP_000143420.1 2697329..2698216(-) (braS) [Staphylococcus aureus strain JP008]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=99624 QMM94_RS13395 WP_000143420.1 2697329..2698216(-) (braS) [Staphylococcus aureus strain JP008]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGTTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAGGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATATGTAAAAGATAATGGTATCGGTATTAGTGAGGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGTCAAAGTAACTCAAGTGGGATTGGCTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993