Detailed information NTG0099618

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: QMM94_RS09415
• Genome accession: NZ_AP027134
• Coordinates: 1937277..1938320 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain JP008
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1932277..1943320

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QMM94_RS09385 (JP008_17950)	-	1932695..1933951 (-)	1257	WP_001793428.1	aminopeptidase	-
QMM94_RS09390 (JP008_17960)	-	1933954..1934154 (-)	201	WP_000180460.1	DUF1128 family protein	-
QMM94_RS09395 (JP008_17970)	-	1934301..1934765 (+)	465	WP_154284135.1	low molecular weight protein-tyrosine-phosphatase	-
QMM94_RS09400 (JP008_17980)	-	1934772..1935047 (+)	276	WP_154284136.1	YtxH domain-containing protein	-
QMM94_RS09405 (JP008_17990)	-	1935325..1936542 (+)	1218	WP_000037079.1	YihY/virulence factor BrkB family protein	-
QMM94_RS09410 (JP008_18000)	vraR	1936658..1937287 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
QMM94_RS09415 (JP008_18010)	vraS	1937277..1938320 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
QMM94_RS09420 (JP008_18020)	liaF	1938317..1939018 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
QMM94_RS09425 (JP008_18030)	-	1939033..1939419 (-)	387	WP_001110179.1	hypothetical protein	-
QMM94_RS09430 (JP008_18040)	map	1939636..1940394 (-)	759	WP_000636144.1	type I methionyl aminopeptidase	-
QMM94_RS09435 (JP008_18050)	-	1940861..1941847 (+)	987	WP_154284137.1	aromatic acid exporter family protein	-
QMM94_RS09440 (JP008_18060)	-	1942278..1942691 (-)	414	WP_154284138.1	hypothetical protein	-
QMM94_RS09445	-	1942720..1942830 (-)	111	WP_154284139.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=99618 QMM94_RS09415 WP_001017131.1 1937277..1938320(-) (vraS) [Staphylococcus aureus strain JP008]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=99618 QMM94_RS09415 WP_001017131.1 1937277..1938320(-) (vraS) [Staphylococcus aureus strain JP008]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTTTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAATTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTGGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTACGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1