Detailed information    

insolico Bioinformatically predicted

Overview

Name   cytR   Type   Regulator
Locus tag   EW035_RS23105 Genome accession   NZ_LR130552
Coordinates   4780425..4781417 (-) Length   330 a.a.
NCBI ID   WP_000224470.1    Uniprot ID   P0ACQ1
Organism   Escherichia coli strain MS14386 isolate MS14386     
Function   promote competence gene expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 4775425..4786417
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EW035_RS23095 yieP 4778317..4779009 (+) 693 WP_001131169.1 FadR/GntR family transcriptional regulator -
  EW035_RS23100 mdtD 4779032..4780459 (+) 1428 WP_001280887.1 multidrug transporter subunit MdtD -
  EW035_RS23105 cytR 4780425..4781417 (-) 993 WP_000224470.1 ribose operon transcriptional repressor RbsR Regulator
  EW035_RS23110 rbsK 4781421..4782350 (-) 930 WP_001300603.1 ribokinase -
  EW035_RS23115 rbsB 4782476..4783366 (-) 891 WP_001056273.1 ribose ABC transporter substrate-binding protein RbsB -
  EW035_RS23120 rbsC 4783391..4784356 (-) 966 WP_000211858.1 ribose ABC transporter permease -
  EW035_RS23125 rbsA 4784361..4785866 (-) 1506 WP_000387753.1 ribose ABC transporter ATP-binding protein RbsA -
  EW035_RS23130 rbsD 4785874..4786293 (-) 420 WP_001297694.1 D-ribose pyranase -

Sequence

Protein


Download         Length: 330 a.a.        Molecular weight: 36611.90 Da        Isoelectric Point: 5.2141

>NTDB_id=996170 EW035_RS23105 WP_000224470.1 4780425..4781417(-) (cytR) [Escherichia coli strain MS14386 isolate MS14386]
MATMKDVARLAGVSTSTVSHVINKDRFVSEAITAKVEAAIKELNYAPSALARSLKLNQTHTIGMLITASTNPFYSELVRG
VERSCFERGYSLVLCNTEGDEQRMNRNLETLMQKRVDGLLLLCTETHQPSREIMQRYPTVPTVMMDWAPFDGDSDLIQDN
SLLGGDLATQYLIDKGHTRIACITGPLDKTPARLRLEGYRAAMKRAGLNIPDGYEVTGDFEFNGGFDAMRQLLSHPLRPQ
AVFTGNDAMAVGVYQALYQAELQVPQDIAVIGYDDIELASFMTPPLTTIHQPKDELGELAIDVLIHRITQPTLQQQRLQL
TPILMERGSA

Nucleotide


Download         Length: 993 bp        

>NTDB_id=996170 EW035_RS23105 WP_000224470.1 4780425..4781417(-) (cytR) [Escherichia coli strain MS14386 isolate MS14386]
TTGGCTACAATGAAAGATGTTGCCCGCCTGGCGGGCGTTTCTACCTCAACAGTTTCTCACGTTATCAATAAAGATCGCTT
CGTCAGTGAAGCGATTACCGCCAAAGTTGAAGCGGCGATTAAAGAACTCAATTACGCGCCATCAGCCCTGGCGCGTAGCC
TCAAACTCAATCAAACACATACCATTGGCATGTTGATCACTGCCAGTACCAATCCTTTCTATTCAGAACTGGTGCGTGGC
GTTGAACGCAGCTGCTTCGAACGCGGTTATAGTCTCGTCCTTTGCAATACCGAAGGAGATGAACAGCGGATGAATCGCAA
TCTGGAAACGCTGATGCAAAAACGCGTTGATGGCTTGCTGTTACTGTGCACCGAAACGCATCAACCTTCGCGTGAAATCA
TGCAACGTTATCCGACAGTGCCTACTGTGATGATGGACTGGGCTCCGTTCGATGGCGACAGCGATCTTATTCAGGATAAC
TCGTTGCTGGGCGGAGACTTAGCAACGCAATATCTGATCGATAAAGGTCATACCCGTATCGCCTGTATTACCGGTCCGCT
GGATAAAACTCCGGCGCGCCTGCGGTTGGAAGGTTATCGGGCGGCGATGAAACGTGCGGGTCTCAACATTCCTGATGGCT
ATGAAGTCACTGGTGATTTTGAATTTAACGGCGGGTTTGACGCCATGCGCCAACTGTTATCACATCCGCTGCGTCCTCAG
GCCGTCTTTACCGGAAATGACGCTATGGCTGTTGGCGTTTACCAGGCGTTATATCAGGCAGAGTTACAGGTTCCGCAGGA
TATCGCGGTGATTGGCTATGACGATATCGAACTGGCAAGCTTTATGACGCCACCATTAACCACTATCCACCAACCGAAAG
ATGAACTGGGGGAGCTGGCGATTGATGTACTCATCCATCGGATAACCCAGCCGACCCTTCAGCAACAACGATTACAACTT
ACTCCGATTCTGATGGAACGCGGTTCGGCTTAG

Domains

Predicted by InterProScan.

Periplasmic binding protein-like domain (Peripla_BP_3)

(169-329)

Bacterial regulatory proteins, lacI family (LacI)

(3-48)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0ACQ1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cytR Vibrio parahaemolyticus RIMD 2210633

37.048

100

0.373
  cytR Vibrio cholerae C6706

39.088

93.03

0.364