Detailed information NTG0996028

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: ABC966_RS12825
• Genome accession: NZ_CP155062
• Coordinates: 2635168..2636055 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus strain CC130-MRSA-XI
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2630168..2641055

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ABC966_RS12795 (ABC966_12795)	-	2630170..2630262 (+)	93	WP_010956583.1	hypothetical protein	-
ABC966_RS12800 (ABC966_12800)	-	2630370..2630867 (-)	498	WP_001065267.1	glutathione peroxidase	-
ABC966_RS12805 (ABC966_12805)	-	2630877..2631137 (-)	261	WP_078103768.1	hypothetical protein	-
ABC966_RS12810 (ABC966_12810)	-	2631519..2631632 (-)	114	WP_072491147.1	hypothetical protein	-
ABC966_RS12815 (ABC966_12815)	-	2632308..2634308 (-)	2001	WP_000776722.1	ABC transporter permease	-
ABC966_RS12820 (ABC966_12820)	-	2634305..2635060 (-)	756	WP_000923770.1	ABC transporter ATP-binding protein	-
ABC966_RS12825 (ABC966_12825)	braS	2635168..2636055 (-)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
ABC966_RS12830 (ABC966_12830)	braR	2636066..2636731 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
ABC966_RS12835 (ABC966_12835)	-	2636757..2636957 (-)	201	WP_000604725.1	hypothetical protein	-
ABC966_RS12840 (ABC966_12840)	-	2637155..2638579 (+)	1425	WP_000953759.1	alkaline phosphatase	-
ABC966_RS12845 (ABC966_12845)	-	2638649..2638759 (+)	111	WP_001791296.1	hypothetical protein	-
ABC966_RS12850 (ABC966_12850)	-	2638862..2639317 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
ABC966_RS12855 (ABC966_12855)	-	2639562..2640323 (-)	762	WP_000323448.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=996028 ABC966_RS12825 WP_000143420.1 2635168..2636055(-) (braS) [Staphylococcus aureus strain CC130-MRSA-XI]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=996028 ABC966_RS12825 WP_000143420.1 2635168..2636055(-) (braS) [Staphylococcus aureus strain CC130-MRSA-XI]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTTATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGGCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993