Detailed information NTG0994993

Bioinformatically predicted

Overview

• Name: irvR
• Type: Regulator
• Locus tag: EW031_RS11355
• Genome accession: NZ_LR130518
• Coordinates: 2141216..2141929 (+)
• Length: 237 a.a.
• NCBI ID: WP_001031454.1
• Uniprot ID: A0A0H2XG68
• Organism: Staphylococcus aureus strain BPH2986 isolate BPH2986
• Function: regulate expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2136216..2146929

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EW031_RS11300	-	2137584..2137847 (-)	264	WP_001205732.1	hypothetical protein	-
EW031_RS11305	-	2137856..2138116 (-)	261	WP_000291513.1	DUF1108 family protein	-
EW031_RS11310	-	2138156..2138416 (-)	261	WP_001549178.1	DUF2482 family protein	-
EW031_RS11315	-	2138511..2138672 (-)	162	WP_001285960.1	DUF1270 domain-containing protein	-
EW031_RS11320	-	2138669..2138989 (-)	321	WP_001120199.1	DUF771 domain-containing protein	-
EW031_RS11325	-	2139048..2139278 (+)	231	WP_000549548.1	hypothetical protein	-
EW031_RS15595	-	2139275..2139451 (-)	177	WP_001001356.1	hypothetical protein	-
EW031_RS11330	-	2139467..2140219 (-)	753	WP_001148642.1	phage antirepressor KilAC domain-containing protein	-
EW031_RS11335	-	2140270..2140599 (+)	330	WP_000180411.1	hypothetical protein	-
EW031_RS11340	-	2140588..2140803 (-)	216	WP_001025404.1	Thoeris anti-defense Tad2 family protein	-
EW031_RS11345	-	2140819..2141082 (-)	264	WP_000854072.1	helix-turn-helix transcriptional regulator	-
EW031_RS11350	-	2141079..2141253 (-)	175	Protein_2108	transcriptional regulator	-
EW031_RS11355	irvR	2141216..2141929 (+)	714	WP_001031454.1	XRE family transcriptional regulator	Regulator
EW031_RS11360	-	2141945..2142877 (+)	933	WP_000759682.1	exonuclease domain-containing protein	-
EW031_RS11365	-	2142883..2143224 (+)	342	WP_000591749.1	hypothetical protein	-
EW031_RS11370	-	2143428..2143610 (+)	183	WP_000705246.1	hypothetical protein	-
EW031_RS11375	-	2143688..2144401 (+)	714	WP_001549185.1	type II toxin-antitoxin system PemK/MazF family toxin	-
EW031_RS11380	-	2144592..2145629 (+)	1038	WP_000857199.1	tyrosine-type recombinase/integrase	-
EW031_RS11385	sph	2145686..2146510 (+)	825	Protein_2115	sphingomyelin phosphodiesterase	-

Sequence

Protein

• Length: 237 a.a.
• Molecular weight: 27017.58 Da
• Isoelectric Point: 5.0545

>NTDB_id=994993 EW031_RS11355 WP_001031454.1 2141216..2141929(+) (irvR) [Staphylococcus aureus strain BPH2986 isolate BPH2986]
MNKERNIIIAKNIRKFLNDSNMSQKKLAELINIKPSTLSDYLNLRSNPSHGVIQRIADVFEVGKSDIDTTYKDDNDITSI
YNKLTPPRQENVLNYANEQLEEQNSKGDNVVDINSYKQEKTPVNVNGCVSAGVGERLHDETLFTEMVKGPIPTHDLALKV
NGDSMEPMFKDGEIIFVEKTHNIKNGQIGIFIIEEEAYVKKVFVEDDRLTLVSLNKDYDDLHFYRNESVRLIGKVIL

Nucleotide

• Length: 714 bp

>NTDB_id=994993 EW031_RS11355 WP_001031454.1 2141216..2141929(+) (irvR) [Staphylococcus aureus strain BPH2986 isolate BPH2986]
ATGAACAAAGAAAGAAATATTATTATAGCCAAAAACATTAGAAAATTTCTCAACGATTCAAATATGTCTCAAAAGAAACT
TGCTGAACTCATTAACATAAAACCATCTACTTTAAGCGATTATTTAAATTTACGTTCCAACCCCTCTCACGGCGTTATAC
AAAGGATAGCTGATGTTTTCGAGGTTGGTAAAAGCGACATAGATACTACATACAAAGACGATAACGACATCACTTCCATA
TACAACAAACTCACACCTCCCCGCCAAGAAAACGTACTTAACTATGCAAATGAACAATTGGAAGAACAGAATTCTAAAGG
AGATAACGTTGTAGATATTAATTCATATAAACAGGAGAAAACTCCAGTTAACGTCAATGGTTGCGTCTCTGCTGGTGTAG
GAGAACGTTTACACGATGAAACGCTATTTACTGAAATGGTTAAAGGACCTATCCCCACACACGATTTAGCGTTAAAAGTA
AATGGTGATTCTATGGAACCTATGTTTAAAGATGGCGAAATCATATTTGTGGAGAAAACTCACAATATAAAGAATGGACA
AATTGGTATATTCATCATTGAAGAAGAAGCGTACGTTAAGAAAGTCTTTGTTGAAGATGATAGATTGACTCTAGTTTCAC
TAAATAAAGATTACGACGATCTACACTTTTATAGAAATGAAAGTGTGAGGTTAATTGGAAAAGTTATTTTATAA

Domains

Predicted by InterProScan.

• Peptidase S24-like (Peptidase_S24) (127-236)

• Helix-turn-helix (HTH_3) (13-63)

3D structure

• AlphaFold DB: A0A0H2XG68

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
irvR	Streptococcus mutans UA159	33.929	100	0.401