Detailed information NTG0994902

Bioinformatically predicted

Overview

• Name: irvR
• Type: Regulator
• Locus tag: EW033_RS11340
• Genome accession: NZ_LR130515
• Coordinates: 2154035..2154748 (+)
• Length: 237 a.a.
• NCBI ID: WP_001031454.1
• Uniprot ID: A0A0H2XG68
• Organism: Staphylococcus aureus strain BPH2947 isolate BPH2947
• Function: regulate expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2149035..2159748

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EW033_RS11275	-	2149790..2150053 (-)	264	WP_001205732.1	hypothetical protein	-
EW033_RS11280	-	2150062..2150322 (-)	261	WP_001814567.1	DUF1108 family protein	-
EW033_RS11285	-	2150303..2150632 (-)	330	WP_000138304.1	hypothetical protein	-
EW033_RS11290	-	2150722..2150883 (-)	162	WP_000066017.1	DUF1270 domain-containing protein	-
EW033_RS11295	-	2150880..2151200 (-)	321	WP_001120197.1	DUF771 domain-containing protein	-
EW033_RS11300	-	2151259..2151891 (+)	633	WP_000275058.1	hypothetical protein	-
EW033_RS11305	-	2151906..2152046 (-)	141	WP_000939496.1	hypothetical protein	-
EW033_RS11310	-	2152077..2152274 (-)	198	WP_001148861.1	hypothetical protein	-
EW033_RS11315	-	2152290..2153039 (-)	750	WP_001148653.1	phage antirepressor KilAC domain-containing protein	-
EW033_RS11320	-	2153090..2153419 (+)	330	WP_000180411.1	hypothetical protein	-
EW033_RS11325	-	2153408..2153623 (-)	216	WP_001025404.1	Thoeris anti-defense Tad2 family protein	-
EW033_RS11330	-	2153639..2153902 (-)	264	WP_000854072.1	helix-turn-helix transcriptional regulator	-
EW033_RS11335	-	2153899..2154072 (-)	174	WP_001801500.1	hypothetical protein	-
EW033_RS11340	irvR	2154035..2154748 (+)	714	WP_001031454.1	XRE family transcriptional regulator	Regulator
EW033_RS11345	-	2154764..2155696 (+)	933	WP_000759682.1	exonuclease domain-containing protein	-
EW033_RS11350	-	2155702..2156043 (+)	342	WP_000591749.1	hypothetical protein	-
EW033_RS11355	-	2156247..2156429 (+)	183	WP_000705248.1	hypothetical protein	-
EW033_RS11360	-	2156529..2156993 (+)	465	WP_000825947.1	hypothetical protein	-
EW033_RS11365	-	2157052..2158089 (+)	1038	WP_000857191.1	tyrosine-type recombinase/integrase	-
EW033_RS11370	sph	2158146..2158970 (+)	825	Protein_2105	sphingomyelin phosphodiesterase	-

Sequence

Protein

• Length: 237 a.a.
• Molecular weight: 27017.58 Da
• Isoelectric Point: 5.0545

>NTDB_id=994902 EW033_RS11340 WP_001031454.1 2154035..2154748(+) (irvR) [Staphylococcus aureus strain BPH2947 isolate BPH2947]
MNKERNIIIAKNIRKFLNDSNMSQKKLAELINIKPSTLSDYLNLRSNPSHGVIQRIADVFEVGKSDIDTTYKDDNDITSI
YNKLTPPRQENVLNYANEQLEEQNSKGDNVVDINSYKQEKTPVNVNGCVSAGVGERLHDETLFTEMVKGPIPTHDLALKV
NGDSMEPMFKDGEIIFVEKTHNIKNGQIGIFIIEEEAYVKKVFVEDDRLTLVSLNKDYDDLHFYRNESVRLIGKVIL

Nucleotide

• Length: 714 bp

>NTDB_id=994902 EW033_RS11340 WP_001031454.1 2154035..2154748(+) (irvR) [Staphylococcus aureus strain BPH2947 isolate BPH2947]
ATGAACAAAGAAAGAAATATTATTATAGCCAAAAACATTAGAAAATTTCTCAACGATTCAAATATGTCTCAAAAGAAACT
TGCTGAACTCATTAACATAAAACCATCTACTTTAAGCGATTATTTAAATTTACGTTCCAACCCCTCTCACGGCGTTATAC
AAAGGATAGCTGATGTTTTCGAGGTTGGTAAAAGCGACATAGATACTACATACAAAGACGATAACGACATCACTTCCATA
TACAACAAACTCACACCTCCCCGCCAAGAAAACGTACTTAACTATGCAAATGAACAATTGGAAGAACAGAATTCTAAAGG
AGATAACGTTGTAGATATTAATTCATATAAACAGGAGAAAACTCCAGTTAACGTCAATGGTTGCGTCTCTGCTGGTGTAG
GAGAACGTTTACACGATGAAACGCTATTTACTGAAATGGTTAAAGGACCTATCCCCACACACGATTTAGCGTTAAAAGTA
AATGGTGATTCTATGGAACCTATGTTTAAAGATGGCGAAATCATATTTGTGGAGAAAACTCACAATATAAAGAATGGACA
AATTGGTATATTCATCATTGAAGAAGAAGCGTACGTTAAGAAAGTCTTTGTTGAAGATGATAGATTGACTCTAGTTTCAC
TAAATAAAGATTACGACGATCTACACTTTTATAGAAATGAAAGTGTGAGGTTAATTGGAAAAGTTATTTTATAA

Domains

Predicted by InterProScan.

• Peptidase S24-like (Peptidase_S24) (127-236)

• Helix-turn-helix (HTH_3) (13-63)

3D structure

• AlphaFold DB: A0A0H2XG68

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
irvR	Streptococcus mutans UA159	33.929	100	0.401