Detailed information    

insolico Bioinformatically predicted

Overview

Name   irvR   Type   Regulator
Locus tag   EW022_RS08830 Genome accession   NZ_LR130240
Coordinates   1766613..1767380 (-) Length   255 a.a.
NCBI ID   WP_003058809.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain PS006 isolate PS006     
Function   regulate expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1761613..1772380
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EW022_RS08815 hexB 1762131..1764113 (-) 1983 WP_021340699.1 DNA mismatch repair endonuclease MutL Machinery gene
  EW022_RS08820 - 1764208..1765359 (-) 1152 WP_003058754.1 tyrosine-type recombinase/integrase -
  EW022_RS09625 - 1765608..1765751 (+) 144 WP_011185066.1 putative holin-like toxin -
  EW022_RS08830 irvR 1766613..1767380 (-) 768 WP_003058809.1 helix-turn-helix transcriptional regulator Regulator
  EW022_RS08835 - 1767534..1767740 (+) 207 WP_002992503.1 helix-turn-helix transcriptional regulator -
  EW022_RS08840 - 1767774..1767974 (+) 201 WP_002992502.1 helix-turn-helix domain-containing protein -
  EW022_RS08845 - 1767995..1768402 (+) 408 WP_002992501.1 hypothetical protein -
  EW022_RS09630 - 1768415..1768537 (+) 123 WP_011285272.1 hypothetical protein -
  EW022_RS08850 - 1768831..1769352 (+) 522 WP_002992498.1 Rha family transcriptional regulator -
  EW022_RS08855 - 1769600..1769773 (+) 174 WP_000132665.1 hypothetical protein -
  EW022_RS08860 - 1769991..1770164 (+) 174 WP_000074663.1 plasmid mobilization protein -
  EW022_RS08865 - 1770326..1770757 (+) 432 WP_136302445.1 hypothetical protein -
  EW022_RS08870 - 1770859..1771191 (+) 333 WP_011285276.1 hypothetical protein -
  EW022_RS08875 - 1771191..1771382 (+) 192 WP_021340709.1 hypothetical protein -
  EW022_RS08880 - 1771394..1771723 (+) 330 WP_003058810.1 hypothetical protein -
  EW022_RS08885 - 1771726..1771998 (+) 273 WP_010922766.1 hypothetical protein -

Sequence

Protein


Download         Length: 255 a.a.        Molecular weight: 28725.00 Da        Isoelectric Point: 4.3544

>NTDB_id=994556 EW022_RS08830 WP_003058809.1 1766613..1767380(-) (irvR) [Streptococcus pyogenes strain PS006 isolate PS006]
MAKNSPQDLINREIFSTNLNMLMAKKNIKQIDIHNKLGIPKSTITGYVKGRSLPTAGNVQKLADFFGVLKSDIDPRFDSN
NIETNSNIIPSTLQKVTSTLSQLEHKRQLNVLDYAETQLEQQNTVEEPQATYYTYNYYDHAASAGTGQYLNDVQVETIEL
PVDYDADFVIPVYGDSMEPEYHSGDYVFIKLSINLSDGDIGVFEYYGDAYIKQLVINDSGAFLHSLNDKYDDILIDRDSD
FRIIGEVIGSFTSKS

Nucleotide


Download         Length: 768 bp        

>NTDB_id=994556 EW022_RS08830 WP_003058809.1 1766613..1767380(-) (irvR) [Streptococcus pyogenes strain PS006 isolate PS006]
ATGGCTAAAAATAGTCCCCAAGATTTAATAAATAGAGAAATTTTCTCAACAAATCTCAACATGCTTATGGCTAAAAAGAA
TATCAAACAGATAGATATTCACAACAAACTAGGAATACCTAAGAGTACGATAACTGGCTATGTTAAAGGTCGTTCACTCC
CAACTGCTGGAAACGTTCAAAAGCTGGCGGACTTCTTCGGAGTTCTAAAATCAGACATTGACCCCCGTTTTGATTCTAAT
AATATTGAAACAAATAGTAATATTATCCCATCAACCCTACAAAAAGTAACATCTACTTTATCTCAGCTAGAACACAAGCG
ACAATTAAACGTCCTTGATTATGCTGAAACACAATTAGAACAACAAAACACAGTAGAAGAACCACAAGCCACCTACTACA
CTTACAACTACTACGACCACGCAGCTTCAGCTGGTACAGGTCAGTATCTAAATGATGTACAAGTAGAAACAATTGAATTA
CCAGTCGATTACGACGCTGATTTTGTCATACCGGTTTATGGCGATTCTATGGAACCCGAATACCATTCTGGGGACTATGT
ATTTATCAAACTATCTATTAACCTGTCAGATGGTGATATAGGAGTTTTTGAGTATTACGGTGATGCTTATATCAAACAAC
TTGTTATAAACGATTCTGGAGCGTTTCTGCATAGTCTGAACGACAAGTATGACGATATACTCATAGATAGAGATAGTGAT
TTCCGTATTATCGGAGAAGTTATTGGGAGTTTTACATCTAAATCATGA

Domains

Predicted by InterProScan.

Helix-turn-helix (HTH_3)

(23-68)

Peptidase S24-like (Peptidase_S24)

(141-248)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  irvR Streptococcus mutans UA159

34

100

0.4