Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutX   Type   Machinery gene
Locus tag   EW022_RS05595 Genome accession   NZ_LR130240
Coordinates   1097554..1098030 (-) Length   158 a.a.
NCBI ID   WP_002984880.1    Uniprot ID   A0A0H2UU18
Organism   Streptococcus pyogenes strain PS006 isolate PS006     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1092554..1103030
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EW022_RS05580 fbp54 1093367..1095019 (+) 1653 WP_002991968.1 Rqc2 family fibronectin-binding protein Fbp54 -
  EW022_RS05585 - 1095078..1096325 (-) 1248 WP_002990000.1 tetratricopeptide repeat protein -
  EW022_RS05590 - 1096315..1097496 (-) 1182 WP_011284730.1 AI-2E family transporter -
  EW022_RS05595 mutX 1097554..1098030 (-) 477 WP_002984880.1 NUDIX hydrolase Machinery gene
  EW022_RS05600 rfbB 1098251..1099291 (-) 1041 WP_011284729.1 dTDP-glucose 4,6-dehydratase -
  EW022_RS05605 - 1099535..1100128 (-) 594 WP_002990099.1 dTDP-4-dehydrorhamnose 3,5-epimerase family protein -
  EW022_RS05610 rfbA 1100128..1100997 (-) 870 WP_011284728.1 glucose-1-phosphate thymidylyltransferase RfbA -
  EW022_RS05615 - 1101056..1102162 (-) 1107 WP_011284727.1 NAD(P)/FAD-dependent oxidoreductase -
  EW022_RS05620 - 1102202..1102990 (-) 789 WP_021340967.1 Nif3-like dinuclear metal center hexameric protein -

Sequence

Protein


Download         Length: 158 a.a.        Molecular weight: 18462.68 Da        Isoelectric Point: 4.3268

>NTDB_id=994527 EW022_RS05595 WP_002984880.1 1097554..1098030(-) (mutX) [Streptococcus pyogenes strain PS006 isolate PS006]
MTQLATICYIDNGDSLLLLHRNKKENDVHKGKWISVGGKLEAGETPDECARREILEETHLTVTEMAFKGIITFPEFTPGH
DWYTYVFKVTGFEGDLISDEESREGTLEWVPYDQVLEKPTWEGDYDIFKWILEDRPFFSAKFTYDQNNQLMDKSVTFY

Nucleotide


Download         Length: 477 bp        

>NTDB_id=994527 EW022_RS05595 WP_002984880.1 1097554..1098030(-) (mutX) [Streptococcus pyogenes strain PS006 isolate PS006]
ATGACTCAATTAGCAACCATTTGTTACATTGATAATGGCGATTCTTTGCTATTATTACACCGCAATAAAAAAGAAAATGA
TGTCCACAAAGGCAAGTGGATTTCAGTTGGGGGTAAGCTCGAGGCTGGTGAGACCCCAGATGAGTGTGCCCGTCGTGAGA
TTTTAGAGGAAACCCATTTGACTGTTACAGAGATGGCCTTTAAAGGAATCATTACTTTTCCAGAATTTACCCCTGGTCAT
GACTGGTATACCTATGTTTTTAAAGTAACAGGATTTGAAGGAGACCTCATTTCCGATGAAGAGTCACGAGAAGGAACCTT
GGAATGGGTACCTTACGATCAAGTGTTGGAAAAGCCAACTTGGGAAGGTGATTATGACATTTTTAAATGGATTTTAGAAG
ACCGTCCTTTTTTCTCTGCCAAATTTACCTATGACCAAAACAACCAACTCATGGATAAATCTGTGACCTTTTATTGA

Domains

Predicted by InterProScan.

NUDIX domain (NUDIX)

(2-130)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2UU18

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutX Streptococcus pneumoniae R6

70.253

100

0.703

Multiple sequence alignment