Detailed information    

insolico Bioinformatically predicted

Overview

Name   xerS   Type   Machinery gene
Locus tag   EW022_RS04780 Genome accession   NZ_LR130240
Coordinates   933292..934362 (+) Length   356 a.a.
NCBI ID   WP_023079834.1    Uniprot ID   Q48TG2
Organism   Streptococcus pyogenes strain PS006 isolate PS006     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 928292..939362
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EW022_RS04760 - 929284..929982 (+) 699 WP_002989743.1 GntR family transcriptional regulator -
  EW022_RS04765 - 930080..930412 (+) 333 WP_002989745.1 putative DNA-binding protein -
  EW022_RS04770 ffh 930427..931989 (+) 1563 WP_021340793.1 signal recognition particle protein -
  EW022_RS04775 - 932124..932822 (-) 699 WP_002993300.1 XRE family transcriptional regulator -
  EW022_RS04780 xerS 933292..934362 (+) 1071 WP_023079834.1 tyrosine recombinase XerS Machinery gene
  EW022_RS04785 - 935061..935543 (+) 483 WP_002984600.1 PASTA domain-containing protein -
  EW022_RS04790 citC 935632..936684 (+) 1053 WP_011284808.1 [citrate (pro-3S)-lyase] ligase -
  EW022_RS04795 - 936794..938188 (-) 1395 WP_014635474.1 oxaloacetate decarboxylase subunit alpha -
  EW022_RS04800 citX 938203..938781 (-) 579 WP_011054513.1 citrate lyase holo-[acyl-carrier protein] synthase -

Sequence

Protein


Download         Length: 356 a.a.        Molecular weight: 41457.54 Da        Isoelectric Point: 9.5552

>NTDB_id=994524 EW022_RS04780 WP_023079834.1 933292..934362(+) (xerS) [Streptococcus pyogenes strain PS006 isolate PS006]
MRRELLLEKIETYKAVMPWYVLDYYQSKLAVPYSFTTLYEYLKEYKRFFDWLMDADLTQAPKIADIDLSTLEHLTKKDLE
AFVLYLRERPSLNTYSTKEGLSQTTINRTLSALSSLYKYLTEEVENDQGEPYFYRNVMKKVSTKKKKETLASRAENIKQK
LFLGDETLAFLDYVDKEYEQKLSNRAKSSFRKNKERDLAIIALLLASGVRLSEAVNLDLKDVNLNMMIIEVIRKGGKRDS
VNVAGFAKGYLESYLAVRQRRYKAEKQDLAFFLTEYRGVPNRMDASSIEKMVGKYSEDFKIRVTPHKLRHTLATRLYDAT
KSQVLVSHQLGHSSTQVTDLYTHIVNDEQKNALDNL

Nucleotide


Download         Length: 1071 bp        

>NTDB_id=994524 EW022_RS04780 WP_023079834.1 933292..934362(+) (xerS) [Streptococcus pyogenes strain PS006 isolate PS006]
ATGAGACGCGAATTATTACTAGAAAAAATTGAAACCTACAAGGCTGTCATGCCTTGGTATGTTTTAGATTATTACCAATC
CAAATTAGCTGTTCCATACAGCTTTACCACCTTATATGAGTATTTAAAAGAATACAAACGCTTTTTTGATTGGCTGATGG
ATGCTGATTTAACGCAGGCGCCAAAGATTGCTGATATTGACTTGAGCACGCTTGAGCACCTTACCAAGAAGGATTTAGAG
GCCTTTGTGCTTTATTTGCGGGAACGACCTTCTCTCAACACCTATTCCACCAAAGAGGGGCTTTCTCAAACCACTATTAA
TCGGACCTTGTCTGCCTTATCAAGCCTTTACAAGTACTTGACTGAAGAGGTTGAAAATGACCAAGGGGAGCCTTATTTTT
ATCGGAATGTTATGAAAAAAGTGTCAACAAAAAAGAAAAAAGAAACCCTGGCCTCCAGAGCGGAAAATATTAAGCAGAAA
CTGTTTTTAGGTGATGAAACTCTAGCTTTCTTGGATTATGTGGATAAGGAATATGAGCAAAAATTGTCTAATCGTGCCAA
ATCTTCTTTCCGTAAAAATAAGGAGAGGGATTTGGCTATTATTGCTCTACTACTTGCTTCTGGTGTTCGTTTGTCTGAAG
CAGTGAATCTTGATTTAAAAGATGTCAATCTAAATATGATGATTATCGAAGTTATTCGCAAAGGCGGAAAACGTGATTCA
GTCAATGTAGCAGGTTTTGCGAAAGGTTATTTGGAGTCTTATTTAGCTGTTCGTCAGAGACGTTACAAGGCTGAAAAACA
GGATCTTGCTTTCTTTTTAACAGAATACCGTGGCGTTCCAAATCGAATGGATGCTTCTAGTATAGAAAAGATGGTTGGCA
AGTACTCTGAGGATTTTAAAATTCGTGTGACTCCTCACAAATTGCGTCATACGCTAGCGACAAGACTATATGATGCTACT
AAATCTCAGGTGTTAGTTAGTCATCAATTAGGCCATTCCTCTACTCAAGTCACGGATCTTTATACCCATATTGTCAATGA
TGAGCAAAAAAATGCTTTAGATAACCTTTAA

Domains

Predicted by InterProScan.

Phage integrase family (Phage_integrase)

(177-344)

Phage integrase, N-terminal SAM-like domain (Phage_int_SAM_4)

(33-122)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q48TG2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  xerS Streptococcus pneumoniae R6

80.618

100

0.806