Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA/nlmT   Type   Regulator
Locus tag   AAYT23_RS02305 Genome accession   NZ_CP154877
Coordinates   448478..449125 (-) Length   215 a.a.
NCBI ID   WP_078064020.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 20234295     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 443478..454125
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AAYT23_RS02275 (AAYT23_02260) - 443813..444142 (-) 330 WP_000132572.1 hypothetical protein -
  AAYT23_RS02280 (AAYT23_02265) - 444418..444756 (+) 339 WP_000876675.1 LytTR family DNA-binding domain-containing protein -
  AAYT23_RS02285 (AAYT23_02270) comE/blpR 444761..445498 (+) 738 WP_001219122.1 response regulator transcription factor Regulator
  AAYT23_RS02290 (AAYT23_02275) - 445512..446852 (+) 1341 WP_001017622.1 sensor histidine kinase -
  AAYT23_RS02295 (AAYT23_02280) blpC 446894..447049 (-) 156 WP_000358817.1 quorum-sensing system pheromone BlpC -
  AAYT23_RS02300 (AAYT23_02285) - 447106..448467 (-) 1362 WP_001069074.1 bacteriocin secretion accessory protein -
  AAYT23_RS02305 (AAYT23_02290) comA/nlmT 448478..449125 (-) 648 WP_078064020.1 ATP-binding cassette domain-containing protein Regulator
  AAYT23_RS02310 (AAYT23_02295) comA/nlmT 449141..450154 (-) 1014 WP_318528993.1 ABC transporter transmembrane domain-containing protein Regulator
  AAYT23_RS02315 (AAYT23_02300) comA/nlmT 450048..450635 (-) 588 WP_000205166.1 cysteine peptidase family C39 domain-containing protein Regulator
  AAYT23_RS02320 (AAYT23_02305) blpI 450917..451114 (+) 198 WP_001093259.1 bacteriocin-like peptide BlpI -
  AAYT23_RS02325 (AAYT23_02310) blpJ 451581..451850 (+) 270 WP_001093248.1 bacteriocin-like peptide BlpJ -
  AAYT23_RS02330 (AAYT23_02315) blpK 451919..452167 (+) 249 WP_000379965.1 bacteriocin-like peptide BlpK -
  AAYT23_RS02335 (AAYT23_02320) cipB 452411..452560 (+) 150 WP_001836413.1 bacteriocin-like peptide BlpO Regulator
  AAYT23_RS02340 - 452596..452661 (+) 66 Protein_459 ComC/BlpC family peptide pheromone/bacteriocin -
  AAYT23_RS02345 (AAYT23_02325) - 452664..452783 (+) 120 WP_000346296.1 PncF family bacteriocin immunity protein -
  AAYT23_RS02350 (AAYT23_02330) - 453264..453622 (+) 359 Protein_461 immunity protein -

Sequence

Protein


Download         Length: 215 a.a.        Molecular weight: 23976.78 Da        Isoelectric Point: 9.2946

>NTDB_id=994434 AAYT23_RS02305 WP_078064020.1 448478..449125(-) (comA/nlmT) [Streptococcus pneumoniae strain 20234295]
MNLTIKQGDKVSLVGVSGSGKTTLAKMIVNFFEPYKGHISINHQDIKNIDKKVLRRHINYLPQQAYIFNGSILENLTLGG
NHMISQEDILKACEVAEIRQDIERMPMGYQTQLSDGAGLSGGQKQRIALARALLTKSPVLILDEATSGLDVLTEKKVIDN
LMSLTDKTILFVAHRLSIAERTNRVIVLDQGKIIEVGSHQELMQAQGFYHHLFNK

Nucleotide


Download         Length: 648 bp        

>NTDB_id=994434 AAYT23_RS02305 WP_078064020.1 448478..449125(-) (comA/nlmT) [Streptococcus pneumoniae strain 20234295]
ATTAATCTCACGATTAAACAAGGAGATAAGGTTAGCCTAGTTGGAGTTAGTGGTTCTGGTAAAACAACTTTAGCCAAAAT
GATTGTCAATTTCTTTGAACCCTACAAAGGGCATATTTCCATCAATCATCAGGATATTAAAAACATTGATAAAAAAGTCT
TGCGCCGTCATATTAATTACCTACCCCAACAAGCCTATATCTTTAATGGCTCTATTTTGGAAAACTTAACCTTGGGCGGT
AATCATATGATTAGTCAAGAAGATATTCTAAAAGCTTGTGAAGTAGCTGAAATCCGTCAAGACATTGAAAGAATGCCTAT
GGGCTATCAAACTCAGCTCTCTGATGGAGCTGGTCTATCAGGAGGACAGAAGCAACGAATCGCTCTCGCTCGTGCTCTTT
TAACTAAATCTCCTGTTTTAATACTAGATGAAGCTACTAGCGGTCTTGATGTCTTGACTGAGAAAAAGGTTATAGATAAT
CTTATGTCTCTAACTGATAAAACCATTCTCTTTGTAGCCCATCGTCTCAGTATAGCCGAACGAACCAACCGTGTCATTGT
TCTTGACCAGGGGAAAATCATTGAAGTTGGTAGTCACCAAGAGTTAATGCAGGCGCAAGGTTTCTACCATCATCTATTCA
ATAAATAA

Domains

Predicted by InterproScan.

ABC transporter (ABC_tran)

(1-147)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA/nlmT Streptococcus mutans UA159

71.495

99.535

0.712
  comA Streptococcus mitis NCTC 12261

66.977

100

0.67
  comA Streptococcus pneumoniae Rx1

66.512

100

0.665
  comA Streptococcus pneumoniae D39

66.512

100

0.665
  comA Streptococcus pneumoniae R6

66.512

100

0.665
  comA Streptococcus mitis SK321

66.512

100

0.665
  comA Streptococcus pneumoniae TIGR4

66.047

100

0.66
  comA Streptococcus gordonii str. Challis substr. CH1

66.047

100

0.66
  rcrQ Streptococcus mutans UA159

38.679

98.605

0.381

Multiple sequence alignment