Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutX   Type   Machinery gene
Locus tag   EW023_RS04165 Genome accession   NZ_LR130239
Coordinates   791412..791888 (+) Length   158 a.a.
NCBI ID   WP_002984880.1    Uniprot ID   A0A0H2UU18
Organism   Streptococcus pyogenes strain PS003 isolate PS003     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 786412..796888
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EW023_RS04130 - 786727..787329 (+) 603 WP_011054796.1 hypothetical protein -
  EW023_RS04135 - 787340..788113 (+) 774 WP_129758826.1 hypothetical protein -
  EW023_RS04140 - 788123..788344 (+) 222 WP_009880241.1 hypothetical protein -
  EW023_RS04145 - 788344..789003 (+) 660 WP_011528570.1 hypothetical protein -
  EW023_RS04150 - 789072..789506 (-) 435 WP_011017966.1 hypothetical protein -
  EW023_RS04155 sda3 789778..790578 (-) 801 WP_011285611.1 streptodornase Sda3 -
  EW023_RS04160 prx 790816..791004 (+) 189 WP_011528571.1 hypothetical protein Regulator
  EW023_RS04165 mutX 791412..791888 (+) 477 WP_002984880.1 NUDIX hydrolase Machinery gene
  EW023_RS04170 - 791946..793127 (+) 1182 WP_011284730.1 AI-2E family transporter -
  EW023_RS04175 - 793117..794364 (+) 1248 WP_050336178.1 tetratricopeptide repeat protein -
  EW023_RS04180 fbp54 794423..796075 (-) 1653 WP_023612033.1 Rqc2 family fibronectin-binding protein Fbp54 -

Sequence

Protein


Download         Length: 158 a.a.        Molecular weight: 18462.68 Da        Isoelectric Point: 4.3268

>NTDB_id=994417 EW023_RS04165 WP_002984880.1 791412..791888(+) (mutX) [Streptococcus pyogenes strain PS003 isolate PS003]
MTQLATICYIDNGDSLLLLHRNKKENDVHKGKWISVGGKLEAGETPDECARREILEETHLTVTEMAFKGIITFPEFTPGH
DWYTYVFKVTGFEGDLISDEESREGTLEWVPYDQVLEKPTWEGDYDIFKWILEDRPFFSAKFTYDQNNQLMDKSVTFY

Nucleotide


Download         Length: 477 bp        

>NTDB_id=994417 EW023_RS04165 WP_002984880.1 791412..791888(+) (mutX) [Streptococcus pyogenes strain PS003 isolate PS003]
ATGACTCAATTAGCAACCATTTGTTACATTGATAATGGCGATTCTTTGCTATTATTACACCGCAATAAAAAAGAAAATGA
TGTCCACAAAGGCAAGTGGATTTCAGTTGGGGGTAAGCTCGAGGCTGGTGAGACCCCAGATGAGTGTGCCCGTCGTGAGA
TTTTAGAGGAAACCCATTTGACTGTTACAGAGATGGCCTTTAAAGGAATCATTACTTTTCCAGAATTTACCCCTGGTCAT
GACTGGTATACCTATGTTTTTAAAGTAACAGGATTTGAAGGAGACCTCATTTCCGATGAAGAGTCACGAGAAGGAACCTT
GGAATGGGTACCTTACGATCAAGTGTTGGAAAAGCCAACTTGGGAAGGTGATTATGACATTTTTAAATGGATTTTAGAAG
ACCGTCCTTTTTTCTCTGCCAAATTTACCTATGACCAAAACAACCAACTCATGGATAAATCTGTGACCTTTTATTGA

Domains

Predicted by InterProScan.

NUDIX domain (NUDIX)

(2-130)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2UU18

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutX Streptococcus pneumoniae R6

70.253

100

0.703

Multiple sequence alignment