Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutX   Type   Machinery gene
Locus tag   EW025_RS03980 Genome accession   NZ_LR130238
Coordinates   762940..763416 (+) Length   158 a.a.
NCBI ID   WP_010922230.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain HKU419 isolate HKU419     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 757940..768416
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EW025_RS03955 - 757981..758769 (+) 789 WP_002984887.1 Nif3-like dinuclear metal center hexameric protein -
  EW025_RS03960 - 758809..759915 (+) 1107 WP_011285493.1 NAD(P)/FAD-dependent oxidoreductase -
  EW025_RS03965 rfbA 759973..760842 (+) 870 WP_136304072.1 glucose-1-phosphate thymidylyltransferase RfbA -
  EW025_RS03970 - 760842..761435 (+) 594 WP_002990099.1 dTDP-4-dehydrorhamnose 3,5-epimerase family protein -
  EW025_RS03975 rfbB 761679..762719 (+) 1041 WP_011285494.1 dTDP-glucose 4,6-dehydratase -
  EW025_RS03980 mutX 762940..763416 (+) 477 WP_010922230.1 NUDIX hydrolase Machinery gene
  EW025_RS03985 - 763474..764655 (+) 1182 WP_002990002.1 AI-2E family transporter -
  EW025_RS03990 - 764645..765892 (+) 1248 WP_010922231.1 tetratricopeptide repeat protein -
  EW025_RS03995 fbp54 765951..767603 (-) 1653 WP_010922232.1 Rqc2 family fibronectin-binding protein Fbp54 -

Sequence

Protein


Download         Length: 158 a.a.        Molecular weight: 18452.64 Da        Isoelectric Point: 4.3268

>NTDB_id=994310 EW025_RS03980 WP_010922230.1 762940..763416(+) (mutX) [Streptococcus pyogenes strain HKU419 isolate HKU419]
MTQLATICYIDNGDSLLLLHRNKKENDVHKGKWISVGGKLEAGETPDECARREILEETHLTVTEMAFKGIITFPEFTPGH
DWYTYVFKVTGFEGDLISDEESREGTLEWVPYDQVLEKPTWEGDYDIFKWILEDRSFFSAKFTYDQNNQLMDKSVTFY

Nucleotide


Download         Length: 477 bp        

>NTDB_id=994310 EW025_RS03980 WP_010922230.1 762940..763416(+) (mutX) [Streptococcus pyogenes strain HKU419 isolate HKU419]
ATGACTCAATTAGCAACCATTTGTTACATTGATAATGGCGATTCTTTGCTATTATTACACCGCAATAAAAAAGAAAATGA
TGTCCACAAAGGCAAGTGGATTTCAGTTGGGGGTAAGCTCGAGGCTGGTGAGACCCCAGATGAGTGTGCCCGTCGTGAGA
TTTTAGAGGAAACCCATTTGACTGTTACAGAGATGGCCTTTAAAGGAATCATTACTTTTCCAGAATTTACCCCTGGTCAT
GACTGGTATACCTATGTTTTTAAAGTAACAGGATTTGAAGGAGACCTCATTTCAGATGAAGAGTCACGAGAAGGAACCTT
GGAATGGGTACCTTACGATCAAGTGTTGGAAAAGCCAACTTGGGAAGGTGATTATGACATTTTTAAATGGATTTTAGAAG
ACCGTTCTTTTTTCTCTGCCAAATTTACCTATGACCAAAACAACCAACTCATGGATAAATCTGTGACCTTTTATTGA

Domains

Predicted by InterProScan.

NUDIX domain (NUDIX)

(2-130)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutX Streptococcus pneumoniae R6

69.62

100

0.696