Detailed information NTG0994280

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: V6C35_RS09610
• Genome accession: NZ_CP154863
• Coordinates: 1958322..1959365 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain BSN31-2
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1953322..1964365

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
V6C35_RS09580 (V6C35_009580)	-	1953743..1954999 (-)	1257	WP_001795108.1	aminopeptidase	-
V6C35_RS09585 (V6C35_009585)	-	1955002..1955202 (-)	201	WP_000180460.1	DUF1128 family protein	-
V6C35_RS09590 (V6C35_009590)	-	1955349..1955813 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
V6C35_RS09595 (V6C35_009595)	-	1955820..1956095 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
V6C35_RS09600 (V6C35_009600)	-	1956373..1957590 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
V6C35_RS09605 (V6C35_009605)	vraR	1957703..1958332 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
V6C35_RS09610 (V6C35_009610)	vraS	1958322..1959365 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
V6C35_RS09615 (V6C35_009615)	liaF	1959362..1960063 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
V6C35_RS09620 (V6C35_009620)	-	1960078..1960464 (-)	387	WP_001110179.1	hypothetical protein	-
V6C35_RS09625 (V6C35_009625)	map	1960681..1961439 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
V6C35_RS09630 (V6C35_009630)	-	1961970..1962956 (+)	987	WP_000999717.1	aromatic acid exporter family protein	-
V6C35_RS09635 (V6C35_009635)	-	1963387..1963806 (-)	420	WP_196755330.1	hypothetical protein	-
V6C35_RS09640 (V6C35_009640)	-	1963835..1963945 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=994280 V6C35_RS09610 WP_001017131.1 1958322..1959365(-) (vraS) [Staphylococcus aureus strain BSN31-2]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=994280 V6C35_RS09610 WP_001017131.1 1958322..1959365(-) (vraS) [Staphylococcus aureus strain BSN31-2]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1