Detailed information NTG0994242

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: V6C34_RS13425
• Genome accession: NZ_CP154861
• Coordinates: 2689387..2690274 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143425.1
• Uniprot ID: A0A389PV50
• Organism: Staphylococcus aureus strain BSN31
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2684387..2695274

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
V6C34_RS13395 (V6C34_13395)	-	2684405..2684497 (+)	93	WP_010956583.1	hypothetical protein	-
V6C34_RS13400 (V6C34_13400)	-	2684605..2685102 (-)	498	WP_001065268.1	glutathione peroxidase	-
V6C34_RS13405 (V6C34_13405)	-	2685112..2685372 (-)	261	WP_001791974.1	hypothetical protein	-
V6C34_RS13410 (V6C34_13410)	-	2685754..2685867 (-)	114	Protein_2602	hypothetical protein	-
V6C34_RS13415 (V6C34_13415)	-	2686527..2688527 (-)	2001	WP_000776751.1	ABC transporter permease	-
V6C34_RS13420 (V6C34_13420)	-	2688524..2689279 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
V6C34_RS13425 (V6C34_13425)	braS	2689387..2690274 (-)	888	WP_000143425.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
V6C34_RS13430 (V6C34_13430)	braR	2690285..2690950 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
V6C34_RS13435 (V6C34_13435)	-	2690976..2691176 (-)	201	WP_000604730.1	hypothetical protein	-
V6C34_RS13440 (V6C34_13440)	-	2691374..2692798 (+)	1425	WP_000953755.1	alkaline phosphatase	-
V6C34_RS13445 (V6C34_13445)	-	2692868..2692978 (+)	111	Protein_2609	hypothetical protein	-
V6C34_RS13450 (V6C34_13450)	-	2693081..2693536 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
V6C34_RS13455 (V6C34_13455)	-	2693781..2694542 (-)	762	WP_000323441.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34006.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=994242 V6C34_RS13425 WP_000143425.1 2689387..2690274(-) (braS) [Staphylococcus aureus strain BSN31]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLETALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=994242 V6C34_RS13425 WP_000143425.1 2689387..2690274(-) (braS) [Staphylococcus aureus strain BSN31]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAACTGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A389PV50

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	100	100	1