Detailed information    

insolico Bioinformatically predicted

Overview

Name   recN   Type   Machinery gene
Locus tag   EW024_RS06215 Genome accession   NZ_LR130237
Coordinates   1202997..1204658 (-) Length   553 a.a.
NCBI ID   WP_002983909.1    Uniprot ID   A0A0H2UW49
Organism   Streptococcus pyogenes strain SP444 isolate SP444     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1197997..1209658
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EW024_RS06180 - 1198167..1198370 (-) 204 Protein_1140 DNA replication protein -
  EW024_RS06185 - 1198367..1198963 (+) 597 Protein_1141 tyrosine-type recombinase/integrase -
  EW024_RS06190 - 1199052..1199327 (-) 276 WP_002983920.1 HU family DNA-binding protein -
  EW024_RS06195 - 1199426..1200013 (-) 588 WP_002989129.1 YpmS family protein -
  EW024_RS06200 - 1199991..1200833 (-) 843 WP_172594861.1 SGNH/GDSL hydrolase family protein -
  EW024_RS06205 - 1200826..1201665 (-) 840 WP_002989125.1 DegV family protein -
  EW024_RS06210 - 1201893..1202825 (-) 933 WP_011528800.1 LPXTG cell wall anchor domain-containing protein -
  EW024_RS06215 recN 1202997..1204658 (-) 1662 WP_002983909.1 DNA repair protein RecN Machinery gene
  EW024_RS06220 - 1204679..1205149 (-) 471 WP_002983907.1 arginine repressor -
  EW024_RS06225 - 1205136..1205963 (-) 828 WP_009880629.1 TlyA family RNA methyltransferase -
  EW024_RS06230 - 1205956..1206828 (-) 873 WP_011284950.1 polyprenyl synthetase family protein -
  EW024_RS06235 - 1206828..1207043 (-) 216 WP_002983901.1 exodeoxyribonuclease VII small subunit -
  EW024_RS06240 xseA 1207021..1208361 (-) 1341 WP_002992349.1 exodeoxyribonuclease VII large subunit -
  EW024_RS06245 - 1208514..1209368 (-) 855 WP_002989114.1 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase -

Sequence

Protein


Download         Length: 553 a.a.        Molecular weight: 62285.44 Da        Isoelectric Point: 4.6120

>NTDB_id=994239 EW024_RS06215 WP_002983909.1 1202997..1204658(-) (recN) [Streptococcus pyogenes strain SP444 isolate SP444]
MLLEISIKNFAIIDEISLNFENGMTVLTGETGAGKSIIIDAMNMMLGARASTEVIRRGANKAEIEGFFSVDATPELVACL
ESSGIAMEEELIIRRDIFANGRSVSRINGQMVNLATLKQVGQFLVDIHGQHDQEELMRPQLHQQILDAFGDKAFEQLKEN
YQLIFDRYKSLRRQVIDKQKNEKEHKDRIDMLAFQIAEIEAAALSRGEDDRLNQERDRLMNHKQIADTLTNAYVMLDNDD
FSSLSNIRSSMNDLLSIEQFDSEYKGMSTSISEAYYILEEVSKQLSDTIDQLDFDGGRLQEIEFRLDTLNSLTRKYGGNV
NDVLDYYDNIIKEYQLLTGDDLSSGDLESELKALEKQLVAAATNLSERRHQLAEQLEAEIKAELKELYMEKADFKVHFTT
SKFNRDGNESLEFYISTNPGEGFKPLVKVASGGELSRLMLAIKAAISRKEDKTSIVFDEVDTGVSGRVAQAIAQKIYKIG
RHGQVLAISHLPQVIAIADYQYFISKESKEESTVSKVRLLTPEERVEEIASMIAGTDMTQAALTQARELLAKH

Nucleotide


Download         Length: 1662 bp        

>NTDB_id=994239 EW024_RS06215 WP_002983909.1 1202997..1204658(-) (recN) [Streptococcus pyogenes strain SP444 isolate SP444]
ATGTTATTAGAAATTTCCATTAAAAATTTTGCTATTATTGATGAAATTTCCCTAAATTTTGAAAATGGTATGACGGTTTT
GACGGGTGAAACTGGAGCAGGAAAGTCTATTATCATTGATGCTATGAATATGATGCTTGGTGCGCGTGCTAGTACAGAAG
TGATTCGTCGTGGAGCTAATAAAGCAGAAATTGAGGGGTTCTTTTCGGTAGATGCTACCCCAGAACTGGTTGCGTGTCTG
GAATCATCAGGTATTGCTATGGAAGAAGAACTGATTATTCGCCGAGATATCTTTGCCAATGGCAGAAGCGTGAGTCGCAT
TAATGGTCAGATGGTTAACCTAGCGACCTTAAAACAGGTCGGACAGTTTTTGGTAGATATTCATGGGCAACATGACCAAG
AAGAATTAATGCGACCACAGCTCCACCAGCAAATTTTGGACGCTTTTGGTGATAAGGCTTTTGAGCAATTGAAAGAGAAC
TATCAGCTTATTTTTGATCGTTATAAAAGCTTGCGTCGCCAGGTTATTGACAAACAAAAAAATGAAAAGGAACACAAAGA
TCGTATTGATATGTTGGCCTTTCAGATAGCAGAAATTGAAGCTGCTGCCTTGAGTCGAGGTGAGGACGACCGGTTAAATC
AAGAACGTGATCGCTTAATGAACCACAAACAAATTGCTGATACCCTGACCAATGCCTACGTCATGCTAGATAATGACGAT
TTTTCAAGTCTATCCAATATTCGCTCTAGCATGAATGACTTACTATCAATTGAGCAGTTTGATTCAGAGTACAAAGGGAT
GTCGACTTCGATTTCTGAAGCCTATTATATTCTTGAAGAAGTGAGCAAGCAATTATCAGATACCATTGACCAACTGGATT
TTGATGGTGGGCGATTACAGGAAATTGAATTTCGCTTGGATACACTCAATAGCTTAACCCGTAAATACGGTGGTAATGTG
AATGATGTGCTTGACTACTACGATAATATTATCAAAGAATACCAGCTATTAACAGGAGACGACTTGTCTTCAGGGGATCT
AGAATCAGAATTGAAAGCCTTAGAAAAACAATTGGTTGCTGCAGCCACTAACTTGAGTGAACGCCGCCATCAATTGGCGG
AGCAATTAGAAGCTGAGATTAAAGCTGAACTTAAGGAACTTTATATGGAAAAAGCAGATTTCAAAGTTCACTTTACCACA
TCAAAATTCAATCGTGATGGTAATGAAAGCTTGGAATTTTACATCTCTACTAATCCAGGCGAAGGATTTAAGCCCCTTGT
CAAGGTGGCTTCTGGAGGAGAGTTATCACGCCTTATGTTAGCCATCAAGGCTGCTATTTCTAGAAAAGAAGATAAGACGA
GTATTGTTTTTGATGAAGTAGATACAGGTGTTTCTGGTCGCGTTGCGCAAGCCATTGCCCAAAAAATTTATAAAATTGGG
CGACATGGGCAAGTTCTCGCTATTTCACACTTACCTCAAGTTATTGCTATTGCTGATTATCAGTATTTTATTTCTAAAGA
AAGTAAAGAAGAGTCCACCGTTTCTAAGGTAAGGTTATTAACTCCTGAAGAACGTGTGGAAGAAATTGCTAGCATGATTG
CAGGAACAGATATGACACAAGCTGCTCTTACGCAGGCTCGTGAACTACTTGCCAAACATTAA

Domains

Predicted by InterProScan.

RecF/RecN/SMC N terminal domain (SMC_N)

(2-511)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2UW49

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  recN Bacillus subtilis subsp. subtilis str. 168

44.014

100

0.452

Multiple sequence alignment