Detailed information    

insolico Bioinformatically predicted

Overview

Name   xerS   Type   Machinery gene
Locus tag   EW021_RS04740 Genome accession   NZ_LR130236
Coordinates   916230..917300 (-) Length   356 a.a.
NCBI ID   WP_002984598.1    Uniprot ID   P0DH45
Organism   Streptococcus pyogenes strain 5448 isolate 5448     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 911230..922300
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EW021_RS04720 citX 911810..912388 (+) 579 WP_010922331.1 citrate lyase holo-[acyl-carrier protein] synthase -
  EW021_RS04725 - 912403..913797 (+) 1395 WP_011285541.1 oxaloacetate decarboxylase subunit alpha -
  EW021_RS04730 citC 913907..914959 (-) 1053 WP_011017789.1 [citrate (pro-3S)-lyase] ligase -
  EW021_RS04735 - 915048..915530 (-) 483 WP_010922334.1 PASTA domain-containing protein -
  EW021_RS04740 xerS 916230..917300 (-) 1071 WP_002984598.1 tyrosine recombinase XerS Machinery gene
  EW021_RS04745 - 917769..918467 (+) 699 WP_002993300.1 XRE family transcriptional regulator -
  EW021_RS04750 ffh 918584..920146 (-) 1563 WP_011285545.1 signal recognition particle protein -
  EW021_RS04755 - 920161..920493 (-) 333 WP_002989745.1 putative DNA-binding protein -
  EW021_RS04760 - 920591..921289 (-) 699 WP_002989743.1 GntR family transcriptional regulator -

Sequence

Protein


Download         Length: 356 a.a.        Molecular weight: 41471.57 Da        Isoelectric Point: 9.5552

>NTDB_id=994122 EW021_RS04740 WP_002984598.1 916230..917300(-) (xerS) [Streptococcus pyogenes strain 5448 isolate 5448]
MRRELLLEKIETYKAIMPWYVLDYYQSKLAVPYSFTTLYEYLKEYKRFFDWLMDADLTQAPKIADIDLSTLEHLTKKDLE
AFVLYLRERPSLNTYSTKEGLSQTTINRTLSALSSLYKYLTEEVENDQGEPYFYRNVMKKVSTKKKKETLASRAENIKQK
LFLGDETLAFLDYVDKEYEQKLSNRAKSSFRKNKERDLAIIALLLASGVRLSEAVNLDLKDVNLNMMIIEVIRKGGKRDS
VNVAGFAKGYLESYLAVRQRRYKAEKQDLAFFLTEYRGVPNRMDASSIEKMVGKYSEDFKIRVTPHKLRHTLATRLYDAT
KSQVLVSHQLGHSSTQVTDLYTHIVNDEQKNALDNL

Nucleotide


Download         Length: 1071 bp        

>NTDB_id=994122 EW021_RS04740 WP_002984598.1 916230..917300(-) (xerS) [Streptococcus pyogenes strain 5448 isolate 5448]
ATGAGACGCGAATTATTACTAGAAAAAATTGAAACCTACAAGGCTATCATGCCCTGGTATGTTTTAGATTATTACCAATC
CAAATTAGCTGTTCCATACAGCTTTACCACCTTATATGAGTATTTAAAAGAATACAAACGCTTTTTTGATTGGCTGATGG
ATGCTGATTTAACGCAGGCGCCAAAGATTGCTGATATTGACTTGAGCACGCTTGAGCACCTTACCAAGAAGGATTTAGAG
GCCTTTGTGCTTTATTTGCGGGAACGACCTTCTCTCAACACCTATTCCACCAAAGAGGGGCTTTCTCAAACCACTATTAA
TCGGACCTTGTCTGCCTTATCAAGCCTTTACAAGTACTTGACTGAAGAGGTTGAAAATGACCAAGGGGAGCCTTATTTTT
ATCGGAATGTTATGAAAAAAGTGTCAACAAAAAAGAAAAAAGAAACCCTGGCTTCCAGAGCGGAAAATATTAAGCAGAAA
CTGTTTTTAGGTGATGAAACTCTAGCTTTCTTGGATTATGTGGATAAGGAATATGAGCAAAAATTGTCTAATCGTGCCAA
ATCTTCTTTCCGTAAAAATAAGGAGAGGGATTTGGCTATTATTGCTCTACTACTTGCTTCTGGTGTTCGTTTGTCTGAAG
CAGTGAATCTTGATTTAAAAGATGTCAATCTAAATATGATGATTATCGAAGTTATTCGCAAAGGCGGAAAACGTGATTCA
GTCAATGTAGCAGGTTTTGCGAAAGGTTATTTGGAGTCTTATTTAGCTGTTCGTCAGAGACGTTACAAGGCTGAAAAACA
GGATCTTGCTTTCTTTTTAACAGAATACCGTGGCGTTCCAAATCGAATGGATGCTTCTAGTATAGAAAAGATGGTTGGCA
AGTACTCTGAGGATTTTAAAATTCGTGTGACTCCTCACAAATTGCGTCATACGCTAGCGACAAGACTATATGATGCTACT
AAATCTCAGGTGTTAGTTAGTCATCAATTAGGCCATTCCTCTACTCAAGTCACGGATCTTTATACCCATATTGTCAATGA
TGAGCAAAAAAATGCTTTAGATAACCTTTAA

Domains

Predicted by InterProScan.

Phage integrase family (Phage_integrase)

(177-344)

Phage integrase, N-terminal SAM-like domain (Phage_int_SAM_4)

(33-122)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0DH45

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  xerS Streptococcus pneumoniae R6

80.618

100

0.806